BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0327.0023.p (240 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH3628 [TK] COG2197 Response regulator containing a CheY-like re... 258 6e-69 BS_degU [TK] COG2197 Response regulator containing a CheY-like r... 246 3e-65 lin2659 [TK] COG2197 Response regulator containing a CheY-like r... 244 1e-64 all4635 [TK] COG2197 Response regulator containing a CheY-like r... 180 2e-45 BS_yfiK [TK] COG2197 Response regulator containing a CheY-like r... 176 4e-44 >BH3628 [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Length = 236 Score = 258 bits (659), Expect = 6e-69, Method: Compositional matrix adjust. Identities = 131/241 (54%), Positives = 175/241 (72%), Gaps = 10/241 (4%) Query: 3 NQSIGKSPIKVLLADDHQLFREGLKRILNMEEDIEVIGECGDGIQVLEFCNENKPDIVLM 62 N+ + ++ I++++ DDHQLFREG+KRIL ME + EV+ + DG +E PD++LM Sbjct: 2 NEQVNENKIQIVIIDDHQLFREGVKRILAMEPEFEVVADGEDGENAVELVETYNPDVILM 61 Query: 63 DINMPIENGVEATQKLREMFPDVKVIILSIHDDESYVFETLRKGANGYLLKDMEAESLIN 122 DINMP NGVEAT+ L + +PDVKV++LSIHDDESYV L+ GA+GYLLK+M+A++LI Sbjct: 62 DINMPKVNGVEATRDLIQRYPDVKVLVLSIHDDESYVTHVLKTGASGYLLKEMDADALIE 121 Query: 123 AIRSVCEGHAFIHPKVTGKLINQLRRMTYLNETGAIAETAVKEAGVKFVAGDNNP---LT 179 A++ V +G A+IHPKVT LI + RR+ +E + +E KE + P LT Sbjct: 122 AVKVVAQGGAYIHPKVTHNLIKEYRRLVNEDEQES-SEIGFKEVEYR------KPLHILT 174 Query: 180 RREAEVLRLMAEGKSNKMIGEYLFISEKTVKNHVSSILQKMEVDDRTQAVINSIKYGWVT 239 RRE EVL+LM +G SN+MIGE L+ISEKTVKNHVS+ILQKM V+DRTQAV+ SIK GWV Sbjct: 175 RRECEVLQLMTDGYSNRMIGEALYISEKTVKNHVSNILQKMNVNDRTQAVVESIKNGWVK 234 Query: 240 L 240 + Sbjct: 235 V 235 >BS_degU [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Length = 229 Score = 246 bits (627), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 123/232 (53%), Positives = 168/232 (72%), Gaps = 5/232 (2%) Query: 9 SPIKVLLADDHQLFREGLKRILNMEEDIEVIGECGDGIQVLEFCNENKPDIVLMDINMPI 68 + + +++ DDHQLFREG+KRIL+ E EV+ E DG + PD+V+MDINMP Sbjct: 2 TKVNIVIIDDHQLFREGVKRILDFEPTFEVVAEGDDGDEAARIVEHYHPDVVIMDINMPN 61 Query: 69 ENGVEATQKLREMFPDVKVIILSIHDDESYVFETLRKGANGYLLKDMEAESLINAIRSVC 128 NGVEAT++L E++P+ KVIILSIHDDE+YV L+ GA GYLLK+M+A++LI A++ V Sbjct: 62 VNGVEATKQLVELYPESKVIILSIHDDENYVTHALKTGARGYLLKEMDADTLIEAVKVVA 121 Query: 129 EGHAFIHPKVTGKLINQLRRMTYLNETGAIAETAVKEAGVKFVAGDNNPLTRREAEVLRL 188 EG +++HPKVT L+N+ RR+ T ++ E + + + LTRRE EVL++ Sbjct: 122 EGGSYLHPKVTHNLVNEFRRLA----TSGVSAHPQHEVYPE-IRRPLHILTRRECEVLQM 176 Query: 189 MAEGKSNKMIGEYLFISEKTVKNHVSSILQKMEVDDRTQAVINSIKYGWVTL 240 +A+GKSN+ IGE LFISEKTVKNHVS+ILQKM V+DRTQAV+ +IK GWV + Sbjct: 177 LADGKSNRGIGESLFISEKTVKNHVSNILQKMNVNDRTQAVVVAIKNGWVEM 228 >lin2659 [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Length = 228 Score = 244 bits (622), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 121/230 (52%), Positives = 162/230 (70%), Gaps = 5/230 (2%) Query: 11 IKVLLADDHQLFREGLKRILNMEEDIEVIGECGDGIQVLEFCNENKPDIVLMDINMPIEN 70 +K+++ DDHQLFREG+KRIL +E+ EV+ E +G ++ E KPDIVLMDINMP N Sbjct: 3 LKIMIVDDHQLFREGIKRILELEDSFEVVAEAENGKNIVAKVREYKPDIVLMDINMPTVN 62 Query: 71 GVEATQKLREMFPDVKVIILSIHDDESYVFETLRKGANGYLLKDMEAESLINAIRSVCEG 130 G++AT+ L FP +KVI+L+IHD + YV E LR GA GYLLK+M+A L+ A++ V G Sbjct: 63 GLDATEMLVRQFPSIKVIVLTIHDTDEYVTEALRAGAVGYLLKEMDAHELVEAVKIVDNG 122 Query: 131 HAFIHPKVTGKLINQLRRMTYLNETGAIAETAVKEAGVKFVAGDNNPLTRREAEVLRLMA 190 A+IHP+V KLI + R + N + + E + + LT RE EVL+L+ Sbjct: 123 GAYIHPRVAIKLIREYRHLASTNTSQGVYGYQQPEVKMPL-----HILTHRECEVLQLLT 177 Query: 191 EGKSNKMIGEYLFISEKTVKNHVSSILQKMEVDDRTQAVINSIKYGWVTL 240 +GKSN+ IGE LFISEKTVKNHVSSILQKM+V+DRTQAV+ +IK+GWV + Sbjct: 178 DGKSNRGIGETLFISEKTVKNHVSSILQKMKVNDRTQAVVTAIKHGWVYI 227 >all4635 [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Length = 219 Score = 180 bits (456), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 99/225 (44%), Positives = 143/225 (63%), Gaps = 15/225 (6%) Query: 11 IKVLLADDHQLFREGLKRILNMEEDIEVIGECGDGIQVLEFCNENKPDIVLMDINMPIEN 70 IKVLL DD L R+GL+ +L +E DIE++GE +G ++ + PD+VLMD+ MPI + Sbjct: 2 IKVLLVDDQNLIRQGLRALLELEPDIEIVGEAENGKIAIDLIPQFHPDVVLMDMRMPIMD 61 Query: 71 GVEATQKLREMFPDVKVIILSIHDDESYVFETLRKGANGYLLKDMEAESLINAIRSVCEG 130 GV ATQ++++ FP+VKV++L+ DD+ YV L+ GA GYLLKD +E L AIR+V +G Sbjct: 62 GVAATQEIQQNFPNVKVLVLTTFDDDEYVKAALQHGAMGYLLKDTPSEELAVAIRAVEKG 121 Query: 131 HAFIHPKVTGKLINQLRRMTYLNETGAIAETAVKEAGVKFVAGDNNPLTRREAEVLRLMA 190 + + P + KL+ Q + N T A T + + LT RE EVLRL+A Sbjct: 122 YTQLGPGIVKKLLVQFQSTP--NHTPP-APTHLAD------------LTPREKEVLRLIA 166 Query: 191 EGKSNKMIGEYLFISEKTVKNHVSSILQKMEVDDRTQAVINSIKY 235 G +N+ I + L+ISE TVKNHV++IL ++ + DRTQA I + Y Sbjct: 167 AGANNREIAQQLYISEGTVKNHVTNILNRLNLRDRTQAAIIANTY 211 >BS_yfiK [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Length = 195 Score = 176 bits (445), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 0/228 (0%), Positives = 0/228 (0%), Gaps = 15/228 (6%) Query: 11 IKVLLADDHQLFREGLKRILNMEEDIEVIGECGDGIQVLEFCNENKPDIVLMDINMPIEN 70 LL+ Q +++ + + Sbjct: 2 TPTLLSAFWTYTLITAMTPGPNNILALSSATSHGFRQSTRVLAGMSLGFLIVMLLCAGIS 61 Query: 71 GVEATQKLREMFPDVKVIILSIHDDESYVFETLRKGANGYLLKDMEAESLINAIRSVCEG 130 A + I + + K S +V Sbjct: 62 FSLAVIDPAAVHLLSWAGAAYIVWLAWKIATSPTKEDGLQAKPISFWASFALQFVNVKII 121 Query: 131 HAFIHPKVTGKLINQLRRMTYLNETGAIAETAVKEAGVKFVAGDNN--PLTRREAEVLRL 188 + T L + +A + A L Sbjct: 122 LYGVTALSTFVLPQTQALSWVVG-------------VSVLLAMIGTFGNVCWALAGHLFQ 168 Query: 189 MAEGKSNKMIGEYLFISEKTVKNHVSSILQKMEVDDRTQAVINSIKYG 236 Sbjct: 169 216 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.136 0.378 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 17,051,134 Number of extensions: 693923 Number of successful extensions: 2962 Number of sequences better than 1.0e-05: 351 Number of HSP's gapped: 2891 Number of HSP's successfully gapped: 355 Length of query: 240 Length of database: 38,378,431 Length adjustment: 103 Effective length of query: 137 Effective length of database: 26,499,029 Effective search space: 3630366973 Effective search space used: 3630366973 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 114 (48.5 bits)