BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0311.0012.p (302 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SPy1634 [K] COG0583 Transcriptional regulator 209 4e-54 HI0775 [K] COG0583 Transcriptional regulator 207 2e-53 SA2330 [K] COG0583 Transcriptional regulator 95 2e-19 cynR [K] COG0583 Transcriptional regulator 79 7e-15 BS_gltC [K] COG0583 Transcriptional regulator 77 3e-14 >SPy1634 [K] COG0583 Transcriptional regulator Length = 298 Score = 209 bits (533), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 103/293 (35%), Positives = 175/293 (59%), Gaps = 1/293 (0%) Query: 5 KHLEYFIEIVNSSCNLSVAAKKLCVTQPSLSLLIKNFEDEENVNLFERYKGRLQNLTPAG 64 K + YFI IV + NLS AA+ L V+QP+LS++I +FE ENV LF+R +GR+ LT G Sbjct: 4 KQIRYFIAIVENHFNLSQAAELLYVSQPTLSMMINDFEKRENVKLFKRKRGRIIGLTYLG 63 Query: 65 ERFFENAKILVKTYQNMLAELREDSFQFKGKXXXXXXXXXXXXXFADILSGMLSTNPDIK 124 + ++++A+ ++ Y +M +L + S KG F++++ ++ NP I+ Sbjct: 64 DNYYKDAQKVLSLYDDMFLKLHDHSKGLKGSINIGIPPLILSVVFSEVMPKLILENPGIQ 123 Query: 125 FEIIEAGAYELRRMLTLKELDFAILLQPTNIDPTTINEYLLQEDELTAFMSSSNPLANHE 184 F + E GAY+L+ L + +D A+LL PT I + Y +Q EL+ +S + LA+ + Sbjct: 124 FNVKEIGAYQLKNELLVGNVDVAVLLSPTGIADNLVETYEIQRSELSVCLSPRHRLASKK 183 Query: 185 KIHWKQLNNEPLAIFNHTFMIHHKLLEQFKKENIQPQISILSASWDFLLQVTK-RSKFIT 243 I W+ L +E LA+F+ +FM+HH +LE ++ ++P I + S+SWDF+L TK +T Sbjct: 184 VIQWEDLTDEQLALFDPSFMVHHLVLEACERHQVRPNIILTSSSWDFMLNSTKINHNVLT 243 Query: 244 ILPSPVHDFFNISDIIEVPFHQPITWKVILCQPAKDRYSHVERHVKKIIIDHF 296 I P P+ + + + DI +P +PI+W+V+L + K YS +E ++ ++ F Sbjct: 244 ICPKPITELYQLKDIKCIPMERPISWRVVLTRLRKKSYSEIEAYIMDDLLQSF 296 >HI0775 [K] COG0583 Transcriptional regulator Length = 315 Score = 207 bits (527), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 107/293 (36%), Positives = 169/293 (57%), Gaps = 1/293 (0%) Query: 5 KHLEYFIEIVNSSCNLSVAAKKLCVTQPSLSLLIKNFEDEENVNLFERYKGRLQNLTPAG 64 +HL YF+ IV++ NLS A++ L V+QP+LS++I FE+ EN+ +F+R G++ LT AG Sbjct: 19 RHLRYFVSIVDNDFNLSRASQNLYVSQPALSMMITEFENRENIQIFKRASGKIIGLTFAG 78 Query: 65 ERFFENAKILVKTYQNMLAELREDSFQFKGKXXXXXXXXXXXXXFADILSGMLSTNPDIK 124 E ++ +AK ++K Y +M L + KG F+ +L ++ NPDI Sbjct: 79 ENYYRDAKEVIKRYNDMRTNLYKSKDCKKGTITIGIPPLVLSAVFSSVLPHLILKNPDIN 138 Query: 125 FEIIEAGAYELRRMLTLKELDFAILLQPTNIDPTTINEYLLQEDELTAFMSSSNPLANHE 184 F I E GAY L+ L L ++D A+LL P I I+ + EL F+S + LA + Sbjct: 139 FIIKEIGAYALKSELLLDKVDLAVLLYPERISKNIIDSIEIHSSELALFLSPKHVLAKKQ 198 Query: 185 KIHWKQLNNEPLAIFNHTFMIHHKLLEQFKKENIQPQISILSASWDFLLQVTKRSK-FIT 243 +I W L+ + +AIF+ TFMIHH L E F++ N P I + S+ WDFLL K +K +T Sbjct: 199 QITWADLHQQKMAIFDQTFMIHHHLKEAFERNNCYPDIVLDSSCWDFLLSAVKTNKELLT 258 Query: 244 ILPSPVHDFFNISDIIEVPFHQPITWKVILCQPAKDRYSHVERHVKKIIIDHF 296 ILP P+ + ++ + + P+ WKV LC+ K Y+H+E ++ +++ F Sbjct: 259 ILPLPMAELYHSKEFLCRKIESPVPWKVTLCRQRKTVYTHLEEYIFDKLLEAF 311 >SA2330 [K] COG0583 Transcriptional regulator Length = 295 Score = 94.7 bits (234), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 64/250 (25%), Positives = 116/250 (46%), Gaps = 4/250 (1%) Query: 5 KHLEYFIEIVNSSCNLSVAAKKLCVTQPSLSLLIKNFEDEENVNLFERYKGRLQNLTPAG 64 KH++YFIE+V ++ A+K L + QP++S IK+ E+E LF+R K L LT AG Sbjct: 7 KHMKYFIEVVKQG-GMTNASKSLYIAQPTISKAIKDIENEMGTPLFDRSKRHLI-LTDAG 64 Query: 65 ERFFENAKILVKTYQNMLAELREDSFQFKGKXXXXXXXXXXXXXFADILSGMLSTNPDIK 124 + F+E +K +V Y + +E+ + G +IL P++ Sbjct: 65 QIFYEKSKEIVALYDYLPSEMERLNGLETGHINMGMSAVMNMKILINILGAFHQQYPNVT 124 Query: 125 FEIIEAGAYELRRMLTLKELDFAILLQPTNIDPTTINEYLLQEDELTAFMSSSNPLANHE 184 + +IE G + + + E+D + P +D + L +++L +S + LA +E Sbjct: 125 YNLIENGGKTIEQQIINDEVDIGVTTLP--VDHHIFDYTTLDKEDLRLIVSREHRLAKYE 182 Query: 185 KIHWKQLNNEPLAIFNHTFMIHHKLLEQFKKENIQPQISILSASWDFLLQVTKRSKFITI 244 + + L E +FN F ++ K++E K P + W + + I+I Sbjct: 183 TVKLEDLAGEDFILFNKDFYLNDKIIENAKNVGFVPNTVAQISQWHVIEDLVTNELGISI 242 Query: 245 LPSPVHDFFN 254 LP+ + + N Sbjct: 243 LPTSISEQLN 252 >cynR [K] COG0583 Transcriptional regulator Length = 299 Score = 79.3 bits (194), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 62/250 (24%), Positives = 114/250 (45%), Gaps = 7/250 (2%) Query: 5 KHLEYFIEIVNSSCNLSVAAKKLCVTQPSLSLLIKNFEDEENVNLFERYKGRLQNLTPAG 64 +H+ YF+ + + + AA L V+QP+LS I+ E+ V LF+R GR LT AG Sbjct: 4 RHINYFLAVAEHG-SFTRAASALHVSQPALSQQIRQLEESLGVPLFDR-SGRTIRLTDAG 61 Query: 65 ERFFENAKILVKTYQNMLAELREDSFQFKGKXXXXXXXXXXXXXFADILSGMLSTNPDIK 124 E + + A ++ + + + +G +++ + P I Sbjct: 62 EVWRQYASRALQELGAGKRAIHDVADLTRGSLRIAVTPTFTSYFIGPLMADFYARYPSIT 121 Query: 125 FEIIEAGAYELRRMLTLKELDFAILLQPTNIDPTTINEYLLQEDELTAFMSSSNPLANHE 184 ++ E ++ ML ELD I P + P LL E L ++ +PLA HE Sbjct: 122 LQLQEMSQEKIEDMLCRDELDVGIAFAPVH-SPELEAIPLLTES-LALVVAQHHPLAVHE 179 Query: 185 KIHWKQLNNEPLAIFNHTFMIHHKLLEQFKKENIQPQISILSASWDFLLQVTKRSKFITI 244 ++ +L++E L + + F ++ +K + PQ+ I + S +L++ +R+ T+ Sbjct: 180 QVALSRLHDEKLVLLSAEFATREQIDHYCEKAGLHPQVVIEANSISAVLELIRRTSLSTL 239 Query: 245 LPSPV---HD 251 LP+ + HD Sbjct: 240 LPAAIATQHD 249 >BS_gltC [K] COG0583 Transcriptional regulator Length = 300 Score = 77.0 bits (188), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 61/243 (25%), Positives = 111/243 (45%), Gaps = 5/243 (2%) Query: 5 KHLEYFIEIVNSSCNLSVAAKKLCVTQPSLSLLIKNFEDEENVNLFERYKGRLQNLTPAG 64 + L YF+E+ ++S AA L V Q ++S I N E+E NV LFER +GR LTP G Sbjct: 4 RQLRYFMEVAERE-HVSEAADHLHVAQSAISRQIANLEEELNVTLFER-EGRNIKLTPIG 61 Query: 65 ERFFENAKILVKTYQNMLAELREDSFQFKGKXXXXXXXXXXXXXFADILSGMLSTNPDIK 124 + F + K +K ++ E +G ++S P ++ Sbjct: 62 KEFLIHVKTAMKAIDYAKEQIDEYLDPHRGTVKIGFPTSLASQLLPTVISAFKEEYPHVE 121 Query: 125 FEIIEAGAYE-LRRMLTLKELDFAILLQPTNIDPTTINEYLLQEDELTAFMSSSNPLANH 183 F ++ G+Y+ L + +++D A LL P + + I +L +++ A + ++PLA Sbjct: 122 F-LLRQGSYKFLIEAVRNRDIDLA-LLGPVPTNFSDITGKILFTEKIYALVPLNHPLAKQ 179 Query: 184 EKIHWKQLNNEPLAIFNHTFMIHHKLLEQFKKENIQPQISILSASWDFLLQVTKRSKFIT 243 + +H L N+ +F F++ ++ K+ P +S D + + +T Sbjct: 180 KTVHLIDLRNDQFVLFPEGFVLREMAIDTCKQAGFAPLVSTEGEDLDAIKGLVSAGMGVT 239 Query: 244 ILP 246 +LP Sbjct: 240 LLP 242 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.136 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 19,851,650 Number of extensions: 783486 Number of successful extensions: 1887 Number of sequences better than 1.0e-05: 37 Number of HSP's gapped: 1894 Number of HSP's successfully gapped: 37 Length of query: 302 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 196 Effective length of database: 26,153,027 Effective search space: 5125993292 Effective search space used: 5125993292 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 115 (48.9 bits)