BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0311.0005.p (227 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ML0125 [GC] COG1819 Glycosyl transferases, related to UDP-glucur... 157 2e-38 L0125 [TK] COG0745 Response regulators consisting of a CheY-like... 157 2e-38 MT0510 [TK] COG0745 Response regulators consisting of a CheY-lik... 154 9e-38 Rv0491 [TK] COG0745 Response regulators consisting of a CheY-lik... 154 2e-37 lin2644 [TK] COG0745 Response regulators consisting of a CheY-li... 152 5e-37 >ML0125 [GC] COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase Length = 233 Score = 157 bits (396), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 85/228 (37%), Positives = 134/228 (58%), Gaps = 5/228 (2%) Query: 2 MKSILIVEDEEAIARVLAAYLKKAGFQVTLAADGRTALEAFETAPPSLILLDINLPNMDG 61 MK IL+V+DE+ I+ ++ L K GF+V A DG ALEAF+ P LILLD+ LP +DG Sbjct: 1 MKKILVVDDEKPISDIVKFNLTKEGFEVFTAFDGEEALEAFKEVQPDLILLDLMLPKLDG 60 Query: 62 FELLGLIREKSSCPVIMLTARDSIXXXXXXXXXXXXXYMSKPFIPEEVVARVNAVLRR-- 119 ++ IR+ S P+IM++A+DS Y++KPF E++AR+ A LRR Sbjct: 61 LDVAREIRKTSDTPIIMVSAKDSEFDKVIGLELGADDYVTKPFSNRELLARIKANLRRIN 120 Query: 120 --PSQWSDGSRKRH-YGSLFIDFGARSVFLNGAEVSLSPRDLSVLLFLAERPNQICTRDQ 176 P++ +D +K G+L I+ + + N ++ L+ R+ +L +LA+ ++ TR+ Sbjct: 121 VAPAESTDNVKKELIIGNLRINPAHYAAYKNDKQLDLTHREFELLYYLAQHLGEVITREN 180 Query: 177 LLEHVWEMDYDGSDRAVDLSIKRLRQALSHWPAEEGEIRTLRGTGYQL 224 LLE VW DY G R VD++++RLR+ + P+ + T RG GY + Sbjct: 181 LLETVWGYDYFGDVRTVDVTVRRLREKVEDTPSRPQYVSTRRGVGYYM 228 >L0125 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 233 Score = 157 bits (396), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 85/228 (37%), Positives = 134/228 (58%), Gaps = 5/228 (2%) Query: 2 MKSILIVEDEEAIARVLAAYLKKAGFQVTLAADGRTALEAFETAPPSLILLDINLPNMDG 61 MK IL+V+DE+ I+ ++ L K GF+V A DG ALEAF+ P LILLD+ LP +DG Sbjct: 1 MKKILVVDDEKPISDIVKFNLTKEGFEVFTAFDGEEALEAFKEVQPDLILLDLMLPKLDG 60 Query: 62 FELLGLIREKSSCPVIMLTARDSIXXXXXXXXXXXXXYMSKPFIPEEVVARVNAVLRR-- 119 ++ IR+ S P+IM++A+DS Y++KPF E++AR+ A LRR Sbjct: 61 LDVAREIRKTSDTPIIMVSAKDSEFDKVIGLELGADDYVTKPFSNRELLARIKANLRRIN 120 Query: 120 --PSQWSDGSRKRH-YGSLFIDFGARSVFLNGAEVSLSPRDLSVLLFLAERPNQICTRDQ 176 P++ +D +K G+L I+ + + N ++ L+ R+ +L +LA+ ++ TR+ Sbjct: 121 VAPAESTDNVKKELIIGNLRINPAHYAAYKNDKQLDLTHREFELLYYLAQHLGEVITREN 180 Query: 177 LLEHVWEMDYDGSDRAVDLSIKRLRQALSHWPAEEGEIRTLRGTGYQL 224 LLE VW DY G R VD++++RLR+ + P+ + T RG GY + Sbjct: 181 LLETVWGYDYFGDVRTVDVTVRRLREKVEDTPSRPQYVSTRRGVGYYM 228 >MT0510 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 230 Score = 154 bits (390), Expect = 9e-38, Method: Compositional matrix adjust. Identities = 87/228 (38%), Positives = 132/228 (57%), Gaps = 6/228 (2%) Query: 1 MMKSILIVEDEEAIARVLAAYLKKAGFQVTLAADGRTALEAFETAPPSLILLDINLPNMD 60 +M S+LIVEDEE++A LA L+K GF+ T+ DG AL F+ A ++LLD+ LP M Sbjct: 3 LMTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMS 62 Query: 61 GFELLGLIREKSSCPVIMLTARDSIXXXXXXXXXXXXXYMSKPFIPEEVVARVNAVLRR- 119 G ++ +R +SS PVIM+TARDS Y++KP+ E++AR+ AVLRR Sbjct: 63 GTDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRG 122 Query: 120 ---PSQWSDGSRKRHYGSLFIDFGARSVFLNGAEVSLSPRDLSVLLFLAERPNQICTRDQ 176 S+ SDG + G + +D V +NG ++L ++ +L +L ++ TR Q Sbjct: 123 GDDDSEMSDGVLES--GPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQ 180 Query: 177 LLEHVWEMDYDGSDRAVDLSIKRLRQALSHWPAEEGEIRTLRGTGYQL 224 L++ VW DY G + +D+ +KRLR + PA + T+RG GY+L Sbjct: 181 LIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKL 228 >Rv0491 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 227 Score = 154 bits (388), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 87/227 (38%), Positives = 131/227 (57%), Gaps = 6/227 (2%) Query: 2 MKSILIVEDEEAIARVLAAYLKKAGFQVTLAADGRTALEAFETAPPSLILLDINLPNMDG 61 M S+LIVEDEE++A LA L+K GF+ T+ DG AL F+ A ++LLD+ LP M G Sbjct: 1 MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG 60 Query: 62 FELLGLIREKSSCPVIMLTARDSIXXXXXXXXXXXXXYMSKPFIPEEVVARVNAVLRR-- 119 ++ +R +SS PVIM+TARDS Y++KP+ E++AR+ AVLRR Sbjct: 61 TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG 120 Query: 120 --PSQWSDGSRKRHYGSLFIDFGARSVFLNGAEVSLSPRDLSVLLFLAERPNQICTRDQL 177 S+ SDG + G + +D V +NG ++L ++ +L +L ++ TR QL Sbjct: 121 DDDSEMSDGVLES--GPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQL 178 Query: 178 LEHVWEMDYDGSDRAVDLSIKRLRQALSHWPAEEGEIRTLRGTGYQL 224 ++ VW DY G + +D+ +KRLR + PA + T+RG GY+L Sbjct: 179 IDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKL 225 >lin2644 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 236 Score = 152 bits (383), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 86/232 (37%), Positives = 128/232 (55%), Gaps = 9/232 (3%) Query: 2 MKSILIVEDEEAIARVLAAYLKKAGFQVTLAADGRTALEAFETAPPSLILLDINLPNMDG 61 M IL+V+DE +I +L ++KAGF V A DGRT E + P LI+LD+ LP MDG Sbjct: 1 MVKILVVDDEASIVTLLQFNIEKAGFDVVTAEDGRTGYELALSEKPDLIVLDLMLPEMDG 60 Query: 62 FELLGLIRE-KSSCPVIMLTARDSIXXXXXXXXXXXXXYMSKPFIPEEVVARVNAVLRRP 120 E+ +R+ K P++MLTA+D YM+KPF P EVVAR+ A+LRR Sbjct: 61 IEVTKKLRQDKVGVPILMLTAKDEELDKIIGLELGADDYMTKPFSPREVVARIKAILRRT 120 Query: 121 SQWSDGSRKRH--------YGSLFIDFGARSVFLNGAEVSLSPRDLSVLLFLAERPNQIC 172 ++ + ++ G L I + V+L + L+P++ +LLFLA ++ Sbjct: 121 EGKAEVTEEKTEDTEATILIGDLKILPDSYEVYLQDDLLDLTPKEFELLLFLANHRGKVF 180 Query: 173 TRDQLLEHVWEMDYDGSDRAVDLSIKRLRQALSHWPAEEGEIRTLRGTGYQL 224 +RDQLL+ VW DY G R VD+ + LR + + I+T+RG GY++ Sbjct: 181 SRDQLLDTVWNYDYVGETRIVDVHVSHLRDKIELDTKQPKYIKTIRGFGYKM 232 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.136 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 15,580,019 Number of extensions: 604078 Number of successful extensions: 2230 Number of sequences better than 1.0e-05: 419 Number of HSP's gapped: 1823 Number of HSP's successfully gapped: 419 Length of query: 227 Length of database: 38,378,431 Length adjustment: 103 Effective length of query: 124 Effective length of database: 26,499,029 Effective search space: 3285879596 Effective search space used: 3285879596 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 114 (48.5 bits)