BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0307.0023.p
         (235 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

CPn0479 [R] COG1235 Metal-dependent hydrolases of the beta-lacta...    59   4e-09
SMc01194 [R] COG1235 Metal-dependent hydrolases of the beta-lact...    59   6e-09
AGc2754 [R] COG1235 Metal-dependent hydrolases of the beta-lacta...    52   6e-07
CT380 [R] COG1235 Metal-dependent hydrolases of the beta-lactama...    51   1e-06

>CPn0479 [R] COG1235 Metal-dependent hydrolases of the beta-lactamase
          superfamily I
          Length = 252

 Score = 59.3 bits (142), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 5/51 (9%), Positives = 11/51 (21%)

Query: 11 RLRSSVLIDNGSDFWVIDCGPDWRRQMELQGRRGMHRLLVTHPHFDHIGGL 61
             +S  +           G D    M  + R  +           +   +
Sbjct: 41 GPGNSTALLQQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIRNWQPV 91


>SMc01194 [R] COG1235 Metal-dependent hydrolases of the beta-lactamase
           superfamily I
          Length = 252

 Score = 58.9 bits (141), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 9/240 (3%), Positives = 30/240 (12%), Gaps = 61/240 (25%)

Query: 5   SSGDNARLRSSVLI-----DNGSDFWVIDCGPDWRRQMELQGRRGMHRLLVTHPHFDHIG 59
           +    A L                   I         +            V     +   
Sbjct: 31  NVEYVADLGCGPGNSTALLQQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIRNWQP 90

Query: 60  GL--------------PEWADSCRWM----GYR-------GELYAPAEVIPVIQRQYPWL 94
                           P+  +    +      +        + +     + + +  +   
Sbjct: 91  VQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMPDNWLEPTHVLMREVAWEQN 150

Query: 95  -----GGQIDMIPCDDGLELDGWQIRTWRVNHGKNGYSYAYRLEKDGYTWVYCPDSISLG 149
                   +  +                      +       + +      Y     S  
Sbjct: 151 YPDRGREPLAGVHA---YYDIL------------SEAGCEVDIWR----TTYYHQMPSHQ 191

Query: 150 PEETKHMHGADLLVLGT-SFYYESAELSTRSVYDMTEAAELLDIVQPVRAVYTHMSHDVD 208
                         L   +   +   L                               + 
Sbjct: 192 AIIDWVTATGLRPWLQDLTESEQQLFLK------RYHQMLEEQYPLQENGQILLAFPRLF 245


>AGc2754 [R] COG1235 Metal-dependent hydrolases of the beta-lactamase
           superfamily I
          Length = 252

 Score = 52.4 bits (124), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 0/245 (0%), Positives = 0/245 (0%), Gaps = 55/245 (22%)

Query: 9   NARLRSSVLI-----DNGSDFWVIDCGPDWRRQMELQGRRGMHRLLVTHPHFDHIGG--- 60
            A L+           + S   + +          ++      + +              
Sbjct: 46  TALLQQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIRNWQPVQALDLIFANASLQW 105

Query: 61  -----------LPEWADSCRW------MGYRGELYAPAEVIPVIQRQYPWLGGQIDMIPC 103
                      +                          EV            G+      
Sbjct: 106 LPDHYELFPHLVSLLNPQGVLAVQMPDNWLEPTHVLMREVAWEQN---YPDRGRE----- 157

Query: 104 DDGLELDG----WQIRTWRVNHGKNGYSYAYRLEKDGYTWVYCPDSISLGPEETKHMHGA 159
                        +            Y +     +     +    + +      + +  +
Sbjct: 158 PLAGVHAYYDILSEAGCEVDIWR-TTYYHQMPSHQ----AIIDWVTATGLRPWLQDLTES 212

Query: 160 DLLVL-GTSFYYESAELSTRSVYDMTEAAELLDIVQPVRAVYTHM----SHDVDMRK--D 212
           +  +           +        + E  ++L     +  V   M               
Sbjct: 213 EQQLFLKRYHQMLEEQYP------LQENGQILLAFPRLFIVARRM                266

Query: 213 YILPG 217
                
Sbjct: 267       271


>CT380 [R] COG1235 Metal-dependent hydrolases of the beta-lactamase
          superfamily I
          Length = 252

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 2/60 (3%), Positives = 2/60 (3%)

Query: 2  EARSSGDNARLRSSVLIDNGSDFWVIDCGPDWRRQMELQGRRGMHRLLVTHPHFDHIGGL 61
                                                        L         I   
Sbjct: 29 LENVEYVADLGCGPGNSTALLQQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIRNW 88


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.321    0.139    0.455 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 19,102,850
Number of extensions: 833076
Number of successful extensions: 2919
Number of sequences better than 1.0e-05: 4
Number of HSP's gapped: 2924
Number of HSP's successfully gapped: 4
Length of query: 235
Length of database: 38,378,431
Length adjustment: 103
Effective length of query: 132
Effective length of database: 26,499,029
Effective search space: 3497871828
Effective search space used: 3497871828
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 114 (48.5 bits)