BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0307.0001.p (386 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM0644 [E] COG0079 Histidinol-phosphate/aromatic aminotransfera... 181 1e-45 BH1589 [E] COG0079 Histidinol-phosphate/aromatic aminotransferas... 146 7e-35 lin1133 [E] COG0079 Histidinol-phosphate/aromatic aminotransfera... 145 1e-34 CAC1369 [E] COG0079 Histidinol-phosphate/aromatic aminotransfera... 138 2e-32 sll1713 [E] COG0079 Histidinol-phosphate/aromatic aminotransfera... 120 4e-27 >STM0644 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Length = 364 Score = 181 bits (460), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 126/355 (35%), Positives = 171/355 (48%), Gaps = 22/355 (6%) Query: 6 GHGGDLLTAAELYGNGSGGAFVDFSANINXXXXXXXXXXXXRDAVSAVTAYPDPGHRRLK 65 HGG++ AA + G S +DFSANIN D + + YPD + L Sbjct: 7 AHGGNIREAATVLG-ISPDQLLDFSANINPLGMPVSVKRALIDNLDCIERYPDADYFHLH 65 Query: 66 SLLAESLGVDREWITVGNGAAESMXXXXXXXXPRRVGIVEPCFSEYRQLAGQFGAEVLPV 125 LA V WI GNG ES+ PRR IV P F+EY + Q G E+ Sbjct: 66 QALARHHQVPASWILAGNGETESIFTVASGLKPRRAMIVTPGFAEYGRALAQSGCEIRRW 125 Query: 126 RGTKEQGYRAGVQSIAGLLEQVDLLFLGQPNNPNGVQYXXXXXXXXXXXXERCGTV---L 182 + G++ + L +D LFL PNNP G+ +RC ++ L Sbjct: 126 SLREADGWQLTDAILEALTPDLDCLFLCTPNNPTGL---LPERPLLQAIADRCKSLNINL 182 Query: 183 AVDEAFIDFIPEERRQSLLPELKSYRHTVLIRSMTKFYAIPGLRLGFTIAAPELAAA-MS 241 +DEAFIDFIP E +P LK H ++RS+TKFYAIPGLRLG+ + + + A A M Sbjct: 183 ILDEAFIDFIPHE--TGFIPALKDNPHIWVLRSLTKFYAIPGLRLGYLVNSDDAAMARMR 240 Query: 242 GKQVTWSVNGLALLAGEACLRSGRGYEERTXXXXXXXXXXXXXXXXXXXCEVPL-----G 296 +Q+ WSVN LA LAGE L+ +++ T C++PL G Sbjct: 241 RQQMPWSVNALAALAGEVALQDS-AWQQAT----WHWLREEGARFYQALCQLPLLTVYPG 295 Query: 297 EANFLLLGLPAPWSAAALQEKLGRRGLLVRSCAMYPGLAPGHIRVAVKSREDNAR 351 AN+LLL LQ +L + +L+RSCA YPGL + RVA++S N R Sbjct: 296 RANYLLLRCER--EDIDLQRRLLTQRILIRSCANYPGLDSRYYRVAIRSAAQNER 348 >BH1589 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Length = 370 Score = 146 bits (368), Expect = 7e-35, Method: Compositional matrix adjust. Identities = 106/351 (30%), Positives = 153/351 (43%), Gaps = 12/351 (3%) Query: 6 GHGGDLLTAAELYGNGSGGAFVDFSANINXXXXXXXXXXXXRDAVSA--VTAYPDPGHRR 63 HG + T A G G +DFS N N R + T YPD Sbjct: 5 NHGANPKTLATQMGTSLTGEAIDFSVNTNPFGPPPQLLAYLRKQLDQGLFTQYPDQEASE 64 Query: 64 LKSLLAESLGVDREWITVGNGAAESMXXXXXXXXPRRVGIVEPCFSEYRQ--LAGQFGAE 121 L +A V + V NGAA+ + +RV IVEP FSEY + LA E Sbjct: 65 LARAIAIKEHVPPSSVLVANGAAQIIYTIAQLWHKQRVAIVEPTFSEYEEACLANDCSVE 124 Query: 122 VLPVRGTKEQGYRAGVQSIAGLLEQVDLLFLGQPNNPNGVQYXXXXXXXXXXXXERCGTV 181 R + + + +L++ DLLF+ PNNP GV Y ++ GT Sbjct: 125 ----RIMLPPPWSLDLDRMTAVLKRTDLLFICHPNNPTGVAYRKEQLIELLELAKQFGTT 180 Query: 182 LAVDEAFIDFIPEERRQSLLPELKSYRHTVLIRSMTKFYAIPGLRLGFTIAAPELAAAMS 241 L +DEAF DF+ E + + + +++RSMTK + IPGLRLG+ I+AP + + Sbjct: 181 LVIDEAFYDFM--EVPITFTAQAAANEGIIVVRSMTKMFTIPGLRLGYAISAPSVIEKLK 238 Query: 242 GKQVTWSVNGLALLAGEACLRSGRGYEERTXXXXXXXXXXXXXXXXXXXCEVPLGEANFL 301 K WSVNGLA AG+ CLR + + +V NF Sbjct: 239 SKIPPWSVNGLADKAGQFCLRETM-FVRDSAQRIAAARAEMQAGFRHLGFDVSPSVVNFF 297 Query: 302 LLGLP-APWSAAALQEKLGRRGLLVRSCAMYPGLAPGHIRVAVKSREDNAR 351 ++ P A+ + L RG ++R +PGL ++RVAVK ++ N + Sbjct: 298 VISDPRESIGMLAMLKGLLDRGFVLRHTENFPGLDGRYLRVAVKDQDTNRK 348 >lin1133 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Length = 301 Score = 145 bits (366), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 0/348 (0%), Positives = 0/348 (0%), Gaps = 9/348 (2%) Query: 7 HGGDLLTAAELYGNGSGGAFVDFSANINXXXXXXXXXXXXRDAVSAVTAYPDPGHRRLKS 66 G + G S I+ + AY Sbjct: 8 CGFIAIVGRPNVG-KSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGAYQAIYVDTPGL 66 Query: 67 LLAESLGVDREWITVGNGAAESMXXXXXXXXPRRVGIVEPCFSEYRQLAGQFGAEVLPVR 126 + E ++R + + + R + + +L V Sbjct: 67 HMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLR--EGKAPVILAVN 124 Query: 127 GTKEQGYRAGVQSIAGLLEQVDL--LFLGQPNNPNGVQYXXXXXXXXXXXXERCGTVLAV 184 +A + L + Sbjct: 125 KVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGLNVDTIAAIVRKHLPEATHHFPEDY 184 Query: 185 DEAFIDFIPEERRQSLLPELKSYRHTVLIRSMTKFYAIPGLRLGFTIAAPE-LAAAMSGK 243 ++ + R G+ I + K Sbjct: 185 ITDRSQRFMASEIIREKLMRFLGAELPYSVTVEIERFVSNERGGYDINGLILVEREGQKK 244 Query: 244 QVTWSVNGLALLAGEACLRSGRGYEERTXXXXXXXXXXXXXXXXXXXCEVPLGEANFLLL 303 Sbjct: 245 304 Query: 304 GLPAPWSAAALQEKLGRRGLLVRSCAMYPGLAPGHIRVAVKSREDNAR 351 Sbjct: 305 --- 349 >CAC1369 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Length = 361 Score = 138 bits (347), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 95/347 (27%), Positives = 152/347 (43%), Gaps = 12/347 (3%) Query: 7 HGGDLLTAAELYGNGSGGAFVDFSANINXXXXXXXXXXXXRDAVSAVTAYPDPGHRRLKS 66 HGGD+ T G G +D+S+NIN + + + YPD +RRL Sbjct: 13 HGGDIYTE----GVFKGRELLDYSSNINPLGIPKSFLNNIDEGIKNLGVYPDVNYRRLNK 68 Query: 67 LLAESLGVDREWITVGNGAAESMXXXXXXXXPRRVGIVEPCFSEYRQLAGQFGAEVLPVR 126 + L + I +GNGA+E + ++ I+ P ++EY A + G V V Sbjct: 69 SIENYLKLKDIGIVLGNGASEIIELSISLF--EKILIIVPSYAEYEINAKKHGVSV--VF 124 Query: 127 GTKEQGYRAGVQSIAGLLEQVDLLFLGQPNNPNGVQYXXXXXXXXXXXXERCGTVLAVDE 186 ++ + I ++ VD + +G PNNPNG E + +DE Sbjct: 125 SYLDENMCIDYEDIISKIDDVDSVIIGNPNNPNGGLINKEKFIHVLKLAEEKKKTIIIDE 184 Query: 187 AFIDFIPEERRQSLLPELKSYRHTVLIRSMTKFYAIPGLRLGFTIA-APELAAAMSGKQV 245 AFI+F + S + E+K+Y +IR+MTKF+A+PG+R G+ I E+AA + KQ Sbjct: 185 AFIEFTGDPS-SSFVGEIKNYSCLFIIRAMTKFFAMPGIRFGYGITNNKEIAAKIKAKQN 243 Query: 246 TWSVNGLALLAGEACLRSGRGYEERTXXXXXXXXXXXXXXXXXXXCEVPLG-EANFLLLG 304 W++N A +A CL+ EE + ANF+L Sbjct: 244 PWNINCFAEMAAINCLKDTNYIEESLLWIKKERKRFIEELNKIGFIKRVFSPHANFVLCR 303 Query: 305 LPAPWSAAALQEKLGRRGLLVRSCAMYPGLAPGHIRVAVKSREDNAR 351 L S L + L + +++R C + GL +R A+K + N + Sbjct: 304 LEN-ISGEKLYDSLLKEDIVIRRCCNFIGLDDSFVRFAIKDEKKNTK 349 >sll1713 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Length = 352 Score = 120 bits (301), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 93/337 (27%), Positives = 154/337 (45%), Gaps = 17/337 (5%) Query: 25 AFVDFSANINXXXXXXXXXXXXRDAVSAVTAYPDPGHRRLKSLLAESLGVDREWITVGNG 84 + +DFSA+IN A+ A+ YPDP + L+ +A+ + +W+ GNG Sbjct: 8 SLLDFSASINPLGPPASVLAAIESALPALRHYPDPQYIHLRQAIADHHQLSMDWVLPGNG 67 Query: 85 AAESMXXXXXXXXPRRVG-IVEPCFSEYRQLAGQFGAEV--LPVRGTKEQGYR-----AG 136 +AE + +V P F +Y + GAE+ +P + + +R + Sbjct: 68 SAELLTLAGRTFASLDCTYVVGPAFGDYGRSWRGAGAELKTIPWQVDQPWPWRKLRSPSE 127 Query: 137 VQSIAGLLEQVDLLFLGQPNNPNGVQYXXXXXXXXXXXXERCGTVLAVDEAFIDFIPEER 196 + + + + L L P+NP+G + + +DEAF+DF+P Sbjct: 128 IANTSAVQSSHHGLILNNPHNPSGTLLAREEILALLPHYQW----VLLDEAFMDFLPPGE 183 Query: 197 RQSLLPELKSYRHTVLIRSMTKFYAIPGLRLGFTIAAPELAAAMSGKQVTWSVNGLALLA 256 QSL+ +L+ + + +++RS+TKFY +PGLRLG+ +A P+L A + W VN LA A Sbjct: 184 EQSLVGDLEKHPNLIILRSLTKFYRLPGLRLGYALAHPDLLAQWQAWRDPWPVNVLAEAA 243 Query: 257 GEACLRSGRGYEERTXXXXXXXXXXXXXXXXXXXCEVPL-GEANFLLLGLPAPWSAAALQ 315 A L + + + PL + NFLL+ P A LQ Sbjct: 244 AIASLEA-EEFRQLVWQWLPPARSALQQDLASLPGLFPLPSQTNFLLVKTTIP--APELQ 300 Query: 316 EKLGRR-GLLVRSCAMYPGLAPGHIRVAVKSREDNAR 351 E+L + +L+R C +P L RVAV++ DN + Sbjct: 301 EELLTKCQILIRDCLSFPELGEDFFRVAVRTMADNQK 337 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.137 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 23,030,798 Number of extensions: 726350 Number of successful extensions: 1769 Number of sequences better than 1.0e-05: 66 Number of HSP's gapped: 1740 Number of HSP's successfully gapped: 66 Length of query: 386 Length of database: 38,378,431 Length adjustment: 108 Effective length of query: 278 Effective length of database: 25,922,359 Effective search space: 7206415802 Effective search space used: 7206415802 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 117 (49.7 bits)