BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0305.0037.p (530 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH3842 [T] COG4753 Response regulator containing CheY-like recei... 159 9e-39 BH1910 [T] COG4753 Response regulator containing CheY-like recei... 126 8e-29 SPy1587 [T] COG4753 Response regulator containing CheY-like rece... 108 3e-23 BH0793 [T] COG4753 Response regulator containing CheY-like recei... 107 4e-23 BH2109 [T] COG4753 Response regulator containing CheY-like recei... 103 5e-22 >BH3842 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 530 Score = 159 bits (403), Expect = 9e-39, Method: Compositional matrix adjust. Identities = 133/537 (24%), Positives = 258/537 (48%), Gaps = 50/537 (9%) Query: 12 LKMLIVDDEPIICKGLRLTIDWAALGIEVIGEAYDGEEALQVMANTEVDFLLSDIRMEGM 71 + +LIVDDE I +GL+L + I ++GEA +G +A++ T+ D ++ DI+M G+ Sbjct: 2 INVLIVDDEQIEREGLKLFLK-DRPNIHIVGEASNGRQAIEKALETQPDLMMMDIKMPGV 60 Query: 72 DGLQLAEQVGQRYPEVRMVIISGYEDFDYARQAMRLGVNDYLLKPVNVDELTGVVGKLAD 131 DG+Q +++ Q+ PE +++S ++ F+YAR+ MR GV +YLLKP +++ + ++ Sbjct: 61 DGVQAVKEIKQQLPETEFIMVSAFDTFEYAREVMRYGVKEYLLKPTTKEDVLTALDRIVG 120 Query: 132 EIRXXXXXXXXXGGKDEVKLWL------THMARHGIAYRRAVPPSLQGAQFRILATQLGS 185 EI D+ KL + + I Y + +Q ++ L + Sbjct: 121 EIEQAREEK-----NDQYKLQQRLEQISSFVQTESILY--LLMDHIQDYEWMEWNEWLRT 173 Query: 186 FHERYA------ELGQEKYEQLQEQWVSRLHQR--LSLPGLRLVSIFDHENLLITLGVSD 237 E YA + G+E + ++QW +R+ + L LP + H ++ L ++ Sbjct: 174 EQEGYAVVFSFHQQGKEIRKTEKQQWHARIKKEIGLQLPKSTVGPFIGHHLPILMLTENE 233 Query: 238 HWMEPQEWRVLLDRLMEEL---IPEAELHCGVSQVYADATETADRCTEAAELLRYSVLGQ 294 + M QE ++ +L+ ++ + A++ GV +Y R + R ++L Sbjct: 234 NGMTKQEREQVVIQLLHKVKQAVQPAKVKTGVGGIY--------RLHFFSTSYREALLAL 285 Query: 295 AVVLDQEAVRQW-----SGVREPAALDIADMVQKLVAALFKQDAGETGGLVSEMLQ-FFR 348 ++ D + + +R L I + KL+ A+ D + +Q R Sbjct: 286 DIIYDHKQASYYFYDKNVKIRADEQLPI-ERENKLIEAIKSGDGEKALQAFDHYVQAILR 344 Query: 349 RESYLLHEIMTVYEELFALLRQRLRKSGI---TGMDYGRQVPDLYLYNSYEALEELIRKD 405 + LH++ ++LF +L + L + G+ T D+ R +++ + E + + Sbjct: 345 CSKHPLHDMRKYLQQLFIILGRLLNEMGLHWETAQDFAR-------FSTVHQVTEHGKSE 397 Query: 406 MADLLELIEQNGTDRSYWIVEKAKRYIEAQYRTDLKASEVAAWLKITPSYFSYIFKQSTG 465 + ++ +++ T ++ A+ Y+ +R L ++A + ++P Y S +FK+ Sbjct: 398 ILHIVRTLQEWRTTDEQSLMLLARDYVHDHFREPLTLDDLAKHIGLSPYYVSKLFKERFD 457 Query: 466 KGFTEYMNELRIEQAKALLASTHDKVFEIADQVGYKEYKYFVTVFKSYTGMTPKEYR 522 F+EY+ +LR+E AK LL+ T + EI ++GYK+ YF VFK TG +P +YR Sbjct: 458 LTFSEYVTQLRVEHAKQLLSLTQKSLKEITYEIGYKDPNYFSRVFKKLTGKSPSDYR 514 >BH1910 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 506 Score = 126 bits (317), Expect = 8e-29, Method: Compositional matrix adjust. Identities = 126/536 (23%), Positives = 220/536 (41%), Gaps = 71/536 (13%) Query: 14 MLIVDDEPIICKGLRLTIDWAALGIEVIGEAYDGEEALQVMANTEVDFLLSDIRMEGMDG 73 ++IVDDE ++ +GL+ I W G VI A +G+E D ++ DIRM +DG Sbjct: 4 VMIVDDEAMVREGLKALISWEEYGFRVIDTARNGKEGFTKYRQLSPDLMIVDIRMPEVDG 63 Query: 74 LQLAEQVGQRYPEVRMVIISGYEDFDYARQAMRLGVNDYLLKPVNVDELTGVVGKLADEI 133 L L E + + +I+SG+ DF+YA++A+ +DYLLKP++ DEL + K+ I Sbjct: 64 LSLIESIRAEDSAIHFIILSGHSDFNYAKKALGCQCDDYLLKPLDEDELIDSLKKVYGRI 123 Query: 134 --RXXXXXXXXXGGKDEVKLWLTHMARHGIAYRRAVPPS--LQGAQFRILAT--QLGSFH 187 + +V++ LT + P S G + AT Q+ Sbjct: 124 TRHHQVHELVERVQEKQVEMVLTELL-------EGTPLSEIPIGKEHNFFATDYQVALVE 176 Query: 188 ERYAELGQEKYEQLQEQWVSRLHQRLSLPGLRLVSIFDHENLLITLGVSDHWMEPQEWRV 247 R L ++ ++EQ + +P + I L G + +W Sbjct: 177 NRQDRLTKQLKRLIEEQ-----EEGYVIPFPEYIVIVCKNRFLQKRGKDHRYHLFAKW-- 229 Query: 248 LLDRLMEELIPEAELH-CGVSQVY--ADATETADRCTEAAELLRYSVLGQAVVLDQEAVR 304 + E ELH C S+V AD E+ E + G+ DQ R Sbjct: 230 ---------LEEEELHACAGSKVVNLADIYESYQSAKRLYEKKFFVEKGRLFTADQLVDR 280 Query: 305 QWSGVREPAALDIADMVQKLVAALFKQDAGETGGLVSEM------------------LQF 346 E + AD + + D G G V+ + + Sbjct: 281 SKPEAPEFSLESYADRL------YYSIDIGNMEGCVAIIEELKNVVIVHLQEEKEIKVAL 334 Query: 347 FRRESYLLHEIMTVYEELFALLRQRLRKSGITGMDYGRQVPDLYLYNSYEALEELIRKDM 406 F+ S +LH+++ + + +L + +G D+Y + + + K + Sbjct: 335 FQLYSNILHQLVRSHPNMEGVLEPLVMNAG-----------DIYQFEHLPGIMAFLTKQL 383 Query: 407 ADLLELIEQNGTDRSYWIVEKAKRYIEAQYRTDLKASEVAAWLKITPSYFSYIFKQSTGK 466 +++ ++ D ++ K I Y +L+ +A+ +Y +FK TG+ Sbjct: 384 KYVIDCMDNGQPD---LLLRKMIALIHKDYAKNLRLETLASVFNYNRAYLGKLFKNYTGE 440 Query: 467 GFTEYMNELRIEQAKALLASTHDKVFEIADQVGYKEYKYFVTVFKSYTGMTPKEYR 522 F Y++++RIE K LL + KV+E+A+++GY YF FK Y G++P +R Sbjct: 441 YFNTYLDKVRIENGKRLLQKGY-KVYEVAEKIGYANVDYFHRKFKKYVGVSPSTFR 495 >SPy1587 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 494 Score = 108 bits (269), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 52/119 (43%), Positives = 76/119 (63%) Query: 13 KMLIVDDEPIICKGLRLTIDWAALGIEVIGEAYDGEEALQVMANTEVDFLLSDIRMEGMD 72 K+L+VDDE +I +GL + IDW ALG EV+ A G+EAL + VD ++SD+ M GM Sbjct: 3 KVLLVDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALAYLTQYPVDVMISDVTMPGMT 62 Query: 73 GLQLAEQVGQRYPEVRMVIISGYEDFDYARQAMRLGVNDYLLKPVNVDELTGVVGKLAD 131 GL L E +P+++ +I+SGY++F Y ++AM L YLLKPV+ EL + + D Sbjct: 63 GLDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGYLLKPVDKAELQAKMKQFKD 121 Score = 75.9 bits (185), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 38/125 (30%), Positives = 68/125 (54%), Gaps = 2/125 (1%) Query: 400 ELIRKDMADLLELIEQNGTDRSYW--IVEKAKRYIEAQYRTDLKASEVAAWLKITPSYFS 457 + I +++ +L++ QN + + +V + I +Y +L +A L + Y Sbjct: 356 DCILRELKKVLDVTNQNNSPEKRYSDLVSETIDCIRKEYHQELTLKAIADRLHVNGVYLG 415 Query: 458 YIFKQSTGKGFTEYMNELRIEQAKALLASTHDKVFEIADQVGYKEYKYFVTVFKSYTGMT 517 FK T + FT+Y+N +RI++A+ LL T+ + EIA + GY YF+ +FK G++ Sbjct: 416 QCFKNETERSFTQYLNHVRIQKAQQLLLYTNQSINEIAYETGYNTNHYFIKMFKKLNGLS 475 Query: 518 PKEYR 522 PKE+R Sbjct: 476 PKEFR 480 >BH0793 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 508 Score = 107 bits (268), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 44/122 (36%), Positives = 80/122 (65%) Query: 12 LKMLIVDDEPIICKGLRLTIDWAALGIEVIGEAYDGEEALQVMANTEVDFLLSDIRMEGM 71 +++++VDDEP+I +GL+ IDW LG E++ A +G EAL++ D L++DI+M Sbjct: 2 IRVMLVDDEPLILEGLKHLIDWGQLGYEIVATARNGVEALEIAKYVSFDLLITDIKMPEK 61 Query: 72 DGLQLAEQVGQRYPEVRMVIISGYEDFDYARQAMRLGVNDYLLKPVNVDELTGVVGKLAD 131 GL+L + +R +R +++SG+++F + +Q + LG+ +YLLKP+N EL + + + Sbjct: 62 TGLELIAALNEREKTIRSIVLSGFQEFHFVKQGLTLGIENYLLKPINEKELISTLSHVKE 121 Query: 132 EI 133 +I Sbjct: 122 KI 123 Score = 79.3 bits (194), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 40/119 (33%), Positives = 66/119 (55%), Gaps = 1/119 (0%) Query: 408 DLLELIEQNGTDRSYW-IVEKAKRYIEAQYRTDLKASEVAAWLKITPSYFSYIFKQSTGK 466 DLLE +++Y I++ ++I + DL + I P Y +F++ G Sbjct: 387 DLLEDDHLQENEKNYSPIIQTVLQHIHQHFSQDLSLKTLGHSFHINPIYLGQLFQREVGC 446 Query: 467 GFTEYMNELRIEQAKALLASTHDKVFEIADQVGYKEYKYFVTVFKSYTGMTPKEYRGLR 525 FT+Y+N+LRI++AK LL +++D+ +I +VGY + YF FK Y MTP E+R + Sbjct: 447 SFTKYLNQLRIDRAKKLLLNSYDRAGQIGKKVGYGDATYFYKQFKKYEAMTPTEWRKVH 505 >BH2109 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 525 Score = 103 bits (258), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 50/119 (42%), Positives = 77/119 (64%), Gaps = 1/119 (0%) Query: 13 KMLIVDDEPIICKGLRLTIDWAALGIEVIGEAYDGEEALQVMANTEVDFLLSDIRMEGMD 72 K+L+ DDE + GL+ I+W G EV EA +GE+A +++ + D +++DIRM D Sbjct: 3 KVLLADDEFFVRHGLKSLIEWEKCGYEVAAEADNGEDAFKLVQEIKPDLVITDIRMPVFD 62 Query: 73 GLQLAEQVGQRYP-EVRMVIISGYEDFDYARQAMRLGVNDYLLKPVNVDELTGVVGKLA 130 GLQL ++V + + +IISGY DF YA++A+R G D++LKP++ DEL + KLA Sbjct: 63 GLQLIQKVNETLSFNTKFIIISGYNDFSYAQKAVRFGAVDFVLKPIDQDELEAALIKLA 121 Score = 79.3 bits (194), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 38/97 (39%), Positives = 57/97 (58%) Query: 427 KAKRYIEAQYRTDLKASEVAAWLKITPSYFSYIFKQSTGKGFTEYMNELRIEQAKALLAS 486 K K YIE Y ++ +A+ + P Y +FK++ G F EY+ +LR+ +AK LL Sbjct: 425 KVKTYIENHYHENISLKSIASLFYMNPVYMGQLFKKTFGVYFKEYLLKLRMNEAKKLLRQ 484 Query: 487 THDKVFEIADQVGYKEYKYFVTVFKSYTGMTPKEYRG 523 T +V+E+A++VG+ YFVT F+ MTP EYR Sbjct: 485 TDMRVYEVAERVGFGSTDYFVTQFEKINKMTPTEYRN 521 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.136 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 39,545,612 Number of extensions: 1624413 Number of successful extensions: 5022 Number of sequences better than 1.0e-05: 299 Number of HSP's gapped: 5120 Number of HSP's successfully gapped: 311 Length of query: 530 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 419 Effective length of database: 25,576,357 Effective search space: 10716493583 Effective search space used: 10716493583 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 118 (50.1 bits)