BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0303.0022.p
         (188 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

aq_407 [O] COG0492 Thioredoxin reductase                               70   1e-12
PAE1725 [O] COG0492 Thioredoxin reductase                              56   3e-08
VNG2301G [O] COG0492 Thioredoxin reductase                             50   3e-06
BH1493 [O] COG0492 Thioredoxin reductase                               49   5e-06

>aq_407 [O] COG0492 Thioredoxin reductase
          Length = 346

 Score = 70.5 bits (171), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 4/165 (2%), Positives = 23/165 (13%), Gaps = 6/165 (3%)

Query: 28  LLIDNDKGMTRRGWYENYYGIAEIG--GPELVETGHKQ--AVKFGAELVADQAVNLTAKG 83
             +     +                    E            +    + +  +       
Sbjct: 38  YAVAQGINLIDVAEMYPVPPRP-ETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNND 96

Query: 84  EGFVIESESGAAYEAKHVILATGVMTDLAAKAGVETKDGTEPRIKTVVAVNAEGRTNI-A 142
           +G   +         + +  +   +                      +  +        +
Sbjct: 97  KGIRPDQALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVS 156

Query: 143 GIWAAGTVAGVSVHAIITAGDGAKVAINIISELNGARYVDHDLLK 187
            +     +A       I     +      +               
Sbjct: 157 LLDTLDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRI 201


>PAE1725 [O] COG0492 Thioredoxin reductase
          Length = 346

 Score = 55.8 bits (133), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 7/82 (8%), Positives = 15/82 (18%), Gaps = 2/82 (2%)

Query: 27  TLLIDNDKG--MTRRGWYENYYGIAEIGGPELVETGHKQAVKFGAELVADQAVNLTAKGE 84
                      +     Y         G  E              +L+    V+  ++  
Sbjct: 36  LDYAVAQGINLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNN 95

Query: 85  GFVIESESGAAYEAKHVILATG 106
              I  +     +     L   
Sbjct: 96  DKGIRPDQALDRKNIREALHDS 117


>VNG2301G [O] COG0492 Thioredoxin reductase
          Length = 346

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 10/165 (6%), Positives = 32/165 (19%), Gaps = 13/165 (7%)

Query: 27  TLLIDN-DKGMTRRGWYENYYGIAE-IGGPELVETGHKQAVKFGAELVAD--QAVNLTAK 82
             L     +G+      E Y                     K G+         V+  ++
Sbjct: 34  AQLDYAVAQGINLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSREKLIIASKVSGPSR 93

Query: 83  GE-GFVIESESGAAYEAKHVILAT----GVMTDLAAKAGVETKDG---TEPRIKTVVAVN 134
                +   ++      +  +  +            +     +      +       +  
Sbjct: 94  NNDKGIRPDQALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDS-A 152

Query: 135 AEGRTNIAGIWAAGTVAGVSVHAIITAGDGAKVAINIISELNGAR 179
                       A       +  I  + + A   +  +   +   
Sbjct: 153 PAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHD 197


>BH1493 [O] COG0492 Thioredoxin reductase
          Length = 346

 Score = 48.5 bits (114), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 10/83 (12%), Positives = 15/83 (18%), Gaps = 7/83 (8%)

Query: 29  LIDNDKG---MTRRGWYENYYGIAE-IGGPELVETGHKQAVKFGAELVADQAVNLTAKGE 84
             D          +    N   +AE    P   ET        G  L    +        
Sbjct: 29  EADAHAQLDYAVAQ--GINLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSREKLIIAS 86

Query: 85  GFVIESESGAAYEAKHVILATGV 107
                S +      +        
Sbjct: 87  KVSGPSRN-NDKGIRPDQALDRK 108


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.314    0.132    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 12,355,080
Number of extensions: 447060
Number of successful extensions: 1983
Number of sequences better than 1.0e-05: 6
Number of HSP's gapped: 1998
Number of HSP's successfully gapped: 6
Length of query: 188
Length of database: 38,378,431
Length adjustment: 100
Effective length of query: 88
Effective length of database: 26,845,031
Effective search space: 2362362728
Effective search space used: 2362362728
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 112 (47.8 bits)