BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0303.0021.p (519 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value DR0744 [T] COG0642 Signal transduction histidine kinase 180 5e-45 Cgl2555 [T] COG0642 Signal transduction histidine kinase 180 6e-45 Rv0758 [T] COG0642 Signal transduction histidine kinase 173 7e-43 MT0783 [T] COG0642 Signal transduction histidine kinase 173 7e-43 BS_phoR_3 [T] COG0642 Signal transduction histidine kinase 170 6e-42 >DR0744 [T] COG0642 Signal transduction histidine kinase Length = 566 Score = 180 bits (456), Expect = 5e-45, Method: Compositional matrix adjust. Identities = 124/287 (43%), Positives = 160/287 (55%), Gaps = 24/287 (8%) Query: 236 KTLVPLSNMGEAAEIIDAGNLSERFPVHQGQTEIDKLSRSFNGMLERLEISFHNEREAKE 295 + L PL + +AAE I L+ER P Q E+ L+RS N ML RLE SF E Sbjct: 282 RALRPLQEVRQAAERIGGQTLTERVPEPQTGDEVQALARSLNAMLGRLEASF-------E 334 Query: 296 QMRRFAADASHELRTPLTSIHGFLEVLLR---GAADNREQLMGALTSMHGESKRINKLVE 352 RRF +DASHELRTP+T+I G LLR RE +L + ES+R+ L+ Sbjct: 335 AQRRFTSDASHELRTPVTAISGHASYLLRRTNPGGQERE----SLNIIRSESERLTNLIT 390 Query: 353 DLLLLARMD-GAPQLN----IKGMMLGEIIAEMQPQLLMLAGDRRVTFDISPGIRGMYDP 407 LL LAR D GA LN + L ++ E+ P L + RV+ P I DP Sbjct: 391 SLLQLARSDSGALTLNPAPIFSRLFLDDVSRELAP-LATGGSELRVS---GPDIPFEGDP 446 Query: 408 DKLKQVILNLFQNAVQHTDAHKGTIHISLTARGTEAELAVQDNGSGIAAEHIPHVFERFY 467 D+L+QVI+NL NA++ A T+ S G E L+V+D+G GI AEH+ +F+RFY Sbjct: 447 DRLRQVIINLVGNALK-AGAKTVTLESSSQEEGREVRLSVRDDGPGIPAEHLSRLFDRFY 505 Query: 468 RSDSSRTRKYGGSGLGLSITKSIVDAHHGGIRVESRPGEGTTFRVTL 514 R + SR+R GG+GLGLSI SIVDAH G I +ES G GT V L Sbjct: 506 RVEDSRSRDQGGAGLGLSIAHSIVDAHGGRIWLESEVGRGTVAHVQL 552 >Cgl2555 [T] COG0642 Signal transduction histidine kinase Length = 485 Score = 180 bits (456), Expect = 6e-45, Method: Compositional matrix adjust. Identities = 131/367 (35%), Positives = 195/367 (53%), Gaps = 32/367 (8%) Query: 158 HTTDKANGG-----YRLMAAPDGSEHLAVFMNLGKPQEARMLLQMSVSTGPLKDVIMQQX 212 HT D A+G +R+MA +G V ++G+ E +L ++ + + +I+ Sbjct: 139 HTVDAASGSASNTPWRVMAEKNGDIITVVGKSMGR--ETNLLYRLVMVQMIIGALIL--- 193 Query: 213 XXXXXXXXXXXXXXXXXXXXXXRKTLVPLSNMGEAAEIIDAGNLSERFPVHQGQTEIDKL 272 R++L PL + E A I G+L R P TE+ +L Sbjct: 194 -----------VAILITSLFLVRRSLRPLREVEETATRIAGGDLDRRVPQWPMTTEVGQL 242 Query: 273 SRSFNGMLERLEISFHNEREAKEQMRRFAADASHELRTPLTSIHGFLEVLLRGAADNREQ 332 S + N MLE+L+ S ++ + QMRRF DASHELRTPLTS+ GF E+ GA D+ Sbjct: 243 SNALNIMLEQLQASILTAQQKEAQMRRFVGDASHELRTPLTSVKGFTELYSSGATDDANW 302 Query: 333 LMGALTSMHGESKRINKLVEDLLLLARMDGAPQLNIKGMMLGEIIAEMQPQLLMLAGDRR 392 +M + + GE++R++ LVEDLL L R +G Q+ + + E+ ++ + DR Sbjct: 303 VM---SKIGGEAQRMSVLVEDLLSLTRAEGQ-QMEKHRVDVLELALAVRGSMRAAWPDRT 358 Query: 393 VTF----DISPGIRGMYDPDKLKQVILNLFQNAVQHTDAHKGTIHISLTARGTEAELAVQ 448 V + P ++G DP +L QV+ NL N + H + I + G + V Sbjct: 359 VNVSNKAESIPVVKG--DPTRLHQVLTNLVANGLNH-GGPDAEVSIEINTDGQNVRILVA 415 Query: 449 DNGSGIAAEHIPHVFERFYRSDSSRTRKYGGSGLGLSITKSIVDAHHGGIRVESRPGEGT 508 DNG G++ E H+FERFYR+DSSR+R GGSGLGL+ITKS+V+ H G + V+S GEGT Sbjct: 416 DNGVGMSEEDAQHIFERFYRADSSRSRASGGSGLGLAITKSLVEGHGGTVTVDSVQGEGT 475 Query: 509 TFRVTLP 515 F +TLP Sbjct: 476 VFTITLP 482 >Rv0758 [T] COG0642 Signal transduction histidine kinase Length = 485 Score = 173 bits (438), Expect = 7e-43, Method: Compositional matrix adjust. Identities = 118/294 (40%), Positives = 172/294 (58%), Gaps = 18/294 (6%) Query: 235 RKTLVPLSNMGEAAEIIDAGNLSERFPVHQGQTEIDKLSRSFNGMLERL-------EISF 287 R++L PL+ + A I AG L R P +TE+ +LS + NGML ++ E S Sbjct: 181 RRSLRPLAEFEQTAAAIGAGQLDRRVPQWHPRTEVGRLSLALNGMLAQIQRAVASAESSA 240 Query: 288 HNEREAKEQMRRFAADASHELRTPLTSIHGFLEVLLRGAADNREQLMGALTSMHGESKRI 347 R+++++MR+F DASHELRTPLT+I GF E+ +GAA + L L+ + E+ R+ Sbjct: 241 EKARDSEDRMRQFITDASHELRTPLTTIRGFAELYRQGAARDVGML---LSRIESEASRM 297 Query: 348 NKLVEDLLLLARMDGAPQLNIKGMMLGEIIAEMQPQLLMLAGDRRVTFDI-----SPGIR 402 LV+DLLLLAR+D L + + L + ++ + RR+T ++ +P + Sbjct: 298 GLLVDDLLLLARLDAHRPLELCRVDLLALASDAAHDARAMDPKRRITLEVLDGPGTPEVL 357 Query: 403 GMYDPDKLKQVILNLFQNAVQHTDAHKGTIHISLTARGTEAELAVQDNGSGIAAEHIPHV 462 G D +L+QV+ NL NA+QHT + + + G +A L V D+G G++ E V Sbjct: 358 G--DESRLRQVLRNLVANAIQHT-PESADVTVRVGTEGDDAILEVADDGPGMSQEDALRV 414 Query: 463 FERFYRSDSSRTRKYGGSGLGLSITKSIVDAHHGGIRVESRPGEGTTFRVTLPR 516 FERFYR+DSSR R GG+GLGLSI S+V AH G + V + GEG FRV+LPR Sbjct: 415 FERFYRADSSRARASGGTGLGLSIVDSLVAAHGGAVTVTTALGEGCCFRVSLPR 468 >MT0783 [T] COG0642 Signal transduction histidine kinase Length = 485 Score = 173 bits (438), Expect = 7e-43, Method: Compositional matrix adjust. Identities = 118/294 (40%), Positives = 172/294 (58%), Gaps = 18/294 (6%) Query: 235 RKTLVPLSNMGEAAEIIDAGNLSERFPVHQGQTEIDKLSRSFNGMLERL-------EISF 287 R++L PL+ + A I AG L R P +TE+ +LS + NGML ++ E S Sbjct: 181 RRSLRPLAEFEQTAAAIGAGQLDRRVPQWHPRTEVGRLSLALNGMLAQIQRAVASAESSA 240 Query: 288 HNEREAKEQMRRFAADASHELRTPLTSIHGFLEVLLRGAADNREQLMGALTSMHGESKRI 347 R+++++MR+F DASHELRTPLT+I GF E+ +GAA + L L+ + E+ R+ Sbjct: 241 EKARDSEDRMRQFITDASHELRTPLTTIRGFAELYRQGAARDVGML---LSRIESEASRM 297 Query: 348 NKLVEDLLLLARMDGAPQLNIKGMMLGEIIAEMQPQLLMLAGDRRVTFDI-----SPGIR 402 LV+DLLLLAR+D L + + L + ++ + RR+T ++ +P + Sbjct: 298 GLLVDDLLLLARLDAHRPLELCRVDLLALASDAAHDARAMDPKRRITLEVLDGPGTPEVL 357 Query: 403 GMYDPDKLKQVILNLFQNAVQHTDAHKGTIHISLTARGTEAELAVQDNGSGIAAEHIPHV 462 G D +L+QV+ NL NA+QHT + + + G +A L V D+G G++ E V Sbjct: 358 G--DESRLRQVLRNLVANAIQHT-PESADVTVRVGTEGDDAILEVADDGPGMSQEDALRV 414 Query: 463 FERFYRSDSSRTRKYGGSGLGLSITKSIVDAHHGGIRVESRPGEGTTFRVTLPR 516 FERFYR+DSSR R GG+GLGLSI S+V AH G + V + GEG FRV+LPR Sbjct: 415 FERFYRADSSRARASGGTGLGLSIVDSLVAAHGGAVTVTTALGEGCCFRVSLPR 468 >BS_phoR_3 [T] COG0642 Signal transduction histidine kinase Length = 431 Score = 170 bits (430), Expect = 6e-42, Method: Compositional matrix adjust. Identities = 13/242 (5%), Positives = 50/242 (20%), Gaps = 8/242 (3%) Query: 285 ISFHNEREAK--EQMRR-FAADASHELRTPLTSIHGFLEVLLRGAADNREQLMGALTSMH 341 ++ + R TP + +L + Sbjct: 36 LASVTGLLIWHFWNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQLRNKKRRRELGN 95 Query: 342 GESKRINKLVEDLLLLARMDGAP-QLNIKGMMLGEIIAEMQPQLLMLAGDRRVTFDISPG 400 + + + G+ + + + + Sbjct: 96 LIKRFRSGAESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPEDNGQNILNLLRYPEFTQY 155 Query: 401 IRGMY---DPDKLKQVILNLFQNAVQHTDAHKGTIHISLTARGTEAELAVQDNGSGIAAE 457 ++ + + +L + +T + + + + E A ++ + ++ E Sbjct: 156 LKTRDFSRPLNLVLNTGRHLEIRVMPYT-HKQLLMVARDVTQMHQLEGARRNFFANVSHE 214 Query: 458 HIPHVFERFYRSDSSRTRKYGGSGLGLSITKSIVDAHHGGIRVESRPGEGTTFRVTLPRS 517 + + + G+ ++ V+ Sbjct: 215 LRTPLTVLQGYLEMMNEQPLEGAVREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTHLL 274 Query: 518 VE 519 E Sbjct: 275 NE 276 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.134 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 34,853,817 Number of extensions: 1426319 Number of successful extensions: 4600 Number of sequences better than 1.0e-05: 278 Number of HSP's gapped: 4150 Number of HSP's successfully gapped: 278 Length of query: 519 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 408 Effective length of database: 25,576,357 Effective search space: 10435153656 Effective search space used: 10435153656 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 118 (50.1 bits)