BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0303.0020.p (228 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Cgl2556 [TK] COG0745 Response regulators consisting of a CheY-li... 202 4e-52 Rv0757 [TK] COG0745 Response regulators consisting of a CheY-lik... 192 4e-49 MT0782 [TK] COG0745 Response regulators consisting of a CheY-lik... 192 5e-49 sll0396 [TK] COG0745 Response regulators consisting of a CheY-li... 181 1e-45 FN0585 [TK] COG0745 Response regulators consisting of a CheY-lik... 173 2e-43 >Cgl2556 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 235 Score = 202 bits (513), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 104/222 (46%), Positives = 150/222 (67%), Gaps = 7/222 (3%) Query: 7 VKLLLVDDEPHILQFLELGLINEGFEVRTAPDGASAIAVAADFKPHVAILDVMMPGMDGF 66 +++L+VDDEP+I++ L + L +GF V TA DG A+ +A +F+P ILDVMMPGMDGF Sbjct: 9 IRVLVVDDEPNIVELLTVSLKFQGFAVMTANDGNEALKIAREFRPDAYILDVMMPGMDGF 68 Query: 67 ELCRYLRSEESELAVIMLTAKDEVDDRVKGLSIGADDYMVKPFSFDELLARIQARLRNQF 126 EL LR E + V+ LTAKD V+ R+ GL+IGADDY+ KPFS +E++ R++ LR Sbjct: 69 ELLTKLRGEGLDSPVLYLTAKDAVEHRIHGLTIGADDYVTKPFSLEEVITRLRVILRRG- 127 Query: 127 PGLLGE-----VRCGPFRIDGRRKEIRHKDEVLELSPTEYELLQYLVINHGLVLSKPMIL 181 G + E ++ ++ E+ E+++LSPTE+ LL+YL++N +VLSK IL Sbjct: 128 -GAVEEDTSTSLQYADLTLNDETHEVTKAGELIDLSPTEFNLLRYLMLNAEVVLSKAKIL 186 Query: 182 DKVWGYDFGGEENIVEVYIRSLREKLGDKDHRIIRTLRGAGY 223 D VW YDFGG+ N+VE YI LR K+ +D ++I+T+RG GY Sbjct: 187 DNVWHYDFGGDGNVVESYISYLRRKVDTQDPQLIQTVRGVGY 228 >Rv0757 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 247 Score = 192 bits (487), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 99/221 (44%), Positives = 144/221 (65%), Gaps = 6/221 (2%) Query: 8 KLLLVDDEPHILQFLELGLINEGFEVRTAPDGASAIAVAADFKPHVAILDVMMPGMDGFE 67 ++L+VDDE +I++ L + L +GFEV TA +GA A+ A + +P ILDVMMPGMDGF Sbjct: 22 RVLVVDDEANIVELLSVSLKFQGFEVYTATNGAQALDRARETRPDAVILDVMMPGMDGFG 81 Query: 68 LCRYLRSEESELAVIMLTAKDEVDDRVKGLSIGADDYMVKPFSFDELLARIQARLR---- 123 + R LR++ + + LTA+D + D++ GL++G DDY+ KPFS +E++AR++ LR Sbjct: 82 VLRRLRADGIDAPALFLTARDSLQDKIAGLTLGGDDYVTKPFSLEEVVARLRVILRRAGK 141 Query: 124 -NQFPGLLGEVRCGPFRIDGRRKEIRHKDEVLELSPTEYELLQYLVINHGLVLSKPMILD 182 N+ P + + +D E+ + + LSPTE+ LL+Y VIN G VLSKP ILD Sbjct: 142 GNKEPRNV-RLTFADIELDEETHEVWKAGQPVSLSPTEFTLLRYFVINAGTVLSKPKILD 200 Query: 183 KVWGYDFGGEENIVEVYIRSLREKLGDKDHRIIRTLRGAGY 223 VW YDFGG+ N+VE Y+ LR K+ + R++ TLRG GY Sbjct: 201 HVWRYDFGGDVNVVESYVSYLRRKIDTGEKRLLHTLRGVGY 241 >MT0782 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 240 Score = 192 bits (487), Expect = 5e-49, Method: Compositional matrix adjust. Identities = 99/221 (44%), Positives = 144/221 (65%), Gaps = 6/221 (2%) Query: 8 KLLLVDDEPHILQFLELGLINEGFEVRTAPDGASAIAVAADFKPHVAILDVMMPGMDGFE 67 ++L+VDDE +I++ L + L +GFEV TA +GA A+ A + +P ILDVMMPGMDGF Sbjct: 15 RVLVVDDEANIVELLSVSLKFQGFEVYTATNGAQALDRARETRPDAVILDVMMPGMDGFG 74 Query: 68 LCRYLRSEESELAVIMLTAKDEVDDRVKGLSIGADDYMVKPFSFDELLARIQARLR---- 123 + R LR++ + + LTA+D + D++ GL++G DDY+ KPFS +E++AR++ LR Sbjct: 75 VLRRLRADGIDAPALFLTARDSLQDKIAGLTLGGDDYVTKPFSLEEVVARLRVILRRAGK 134 Query: 124 -NQFPGLLGEVRCGPFRIDGRRKEIRHKDEVLELSPTEYELLQYLVINHGLVLSKPMILD 182 N+ P + + +D E+ + + LSPTE+ LL+Y VIN G VLSKP ILD Sbjct: 135 GNKEPRNV-RLTFADIELDEETHEVWKAGQPVSLSPTEFTLLRYFVINAGTVLSKPKILD 193 Query: 183 KVWGYDFGGEENIVEVYIRSLREKLGDKDHRIIRTLRGAGY 223 VW YDFGG+ N+VE Y+ LR K+ + R++ TLRG GY Sbjct: 194 HVWRYDFGGDVNVVESYVSYLRRKIDTGEKRLLHTLRGVGY 234 >sll0396 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 224 Score = 181 bits (458), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 94/217 (43%), Positives = 142/217 (65%), Gaps = 1/217 (0%) Query: 8 KLLLVDDEPHILQFLELGLINEGFEVRTAPDGASAIAVAADFKPHVAILDVMMPGMDGFE 67 ++L+V++E + +F+EL L EG++V A DG A +F P + I++ +PGM G E Sbjct: 4 RVLVVEEEEKLARFMELELKYEGYDVSVARDGLKGFTQAQEFPPDLIIVNGALPGMSGLE 63 Query: 68 LCRYLRSEESELAVIMLTAKDEVDDRVKGLSIGADDYMVKPFSFDELLARIQARLRNQFP 127 LCR LR S + +I++TAKD+V++RV GL GADDY+VKPF+ DE ARI+ +LR Sbjct: 64 LCRRLREMGSRIPIILITAKDDVEERVMGLDAGADDYIVKPFNSDEFFARIRVQLRRTHT 123 Query: 128 GLLGEVRCGPFRIDGRRKEIRHKDEVLELSPTEYELLQYLVINHGLVLSKPMILDKVWGY 187 ++ R + +EI+ D +++L+ E+ELL YL+ + VL++ IL++VWGY Sbjct: 124 TSDEVLQFADLRFNRSTREIQRGDRLIDLTAKEFELLDYLLSHARQVLTREQILERVWGY 183 Query: 188 DFGGEENIVEVYIRSLREKL-GDKDHRIIRTLRGAGY 223 DF G+ NI+EVYIR LR KL + R+I+T+RG GY Sbjct: 184 DFMGDSNIIEVYIRYLRLKLEAAGEPRLIQTVRGVGY 220 >FN0585 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 224 Score = 173 bits (439), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 89/218 (40%), Positives = 141/218 (64%), Gaps = 1/218 (0%) Query: 7 VKLLLVDDEPHILQFLELGLINEGFEVRTAPDGASAIAVAADFKPHVAILDVMMPGMDGF 66 +K+L+V+DE + + L F V + DG A+ + V ILDVMMP M+G+ Sbjct: 1 MKILVVEDEKDLNNIISKHLKKNNFSVDSVFDGEEALEYLSYGDYDVIILDVMMPKMNGY 60 Query: 67 ELCRYLRSEESELAVIMLTAKDEVDDRVKGLSIGADDYMVKPFSFDELLARIQARLRNQF 126 E+ + LR+ ++E AV+MLTA+D +D+++KGL +GADDY+VKPF F EL+ARI+A +R ++ Sbjct: 61 EVVKNLRANKNETAVLMLTARDGIDEKIKGLDLGADDYLVKPFDFRELIARIRALVRRKY 120 Query: 127 PGLLGEVRCGPFRIDGRRKEIRHKDEVLELSPTEYELLQYLVINHGLVLSKPMILDKVWG 186 + E++ +D +K + + +EL+ EYE+L+YL+ N G VLS+ I D VW Sbjct: 121 GNISNELQIDDLIVDTSKKSVTRAGKNIELTGKEYEVLEYLIQNKGRVLSRDKIRDGVWD 180 Query: 187 YDFGGEENIVEVYIRSLREKLGDKDHR-IIRTLRGAGY 223 Y + GE NI++V I+++R+K+ D + +I T RG GY Sbjct: 181 YAYEGESNIIDVLIKNIRKKIDLGDSKPLIHTKRGLGY 218 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.323 0.144 0.416 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 17,975,414 Number of extensions: 730888 Number of successful extensions: 2522 Number of sequences better than 1.0e-05: 518 Number of HSP's gapped: 2089 Number of HSP's successfully gapped: 518 Length of query: 228 Length of database: 38,378,431 Length adjustment: 103 Effective length of query: 125 Effective length of database: 26,499,029 Effective search space: 3312378625 Effective search space used: 3312378625 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 114 (48.5 bits)