BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0301.0011.p (345 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0856 [K] COG1609 Transcriptional regulators 223 4e-58 SP2112 [K] COG1609 Transcriptional regulators 203 4e-52 PA1949 [K] COG1609 Transcriptional regulators 189 5e-48 BS_ccpA [K] COG1609 Transcriptional regulators 182 1e-45 RSc1014 [K] COG1609 Transcriptional regulators 180 2e-45 >CAC0856 [K] COG1609 Transcriptional regulators Length = 346 Score = 223 bits (568), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 127/338 (37%), Positives = 199/338 (58%), Gaps = 9/338 (2%) Query: 1 MTVTIKDVAKKAGVSPSTVSRVLSGHPRISLETSRKVKEIMEEMGYTPNMMAKSLVSKTT 60 M TI+DVAK A VSPSTVSRVL+ +IS ET +V + ++++ Y N +A+SL + +T Sbjct: 12 MAATIRDVAKLANVSPSTVSRVLNDSNKISCETKERVIKAIKKLDYHANAIARSLANNST 71 Query: 61 NSICIILPKPAEELFSNLFFMELIRGIVTQSSRSGYDVLISSGANEKEELESVSRLLKGR 120 + +I+P A+ LF N FF++ +RGI + + Y ++ G++EKEE+ + + ++ + Sbjct: 72 KILGLIVPNEAKNLFRNPFFIKAMRGISLCAHENEYYIMYDFGSSEKEEVSLIKKYVQSK 131 Query: 121 RVDGVILLYSRKDDAVIDFLESGGYPFVLVGRSDRYEDILSVDNDNIMASFDATNHLISM 180 VDG+ILL RK+D IDFL+ YPFV++GR + + ++ VDNDN A +D + LI Sbjct: 132 LVDGIILLTVRKNDKCIDFLKRLKYPFVVIGRPEESKGVMWVDNDNFKAMYDLVDGLIKR 191 Query: 181 GHERIGFVSGPPNLIVSRDRLEGYRKAMANSGLEMRAEWIVEGE-FLQDSGYRAMSFFMN 239 G E I F+ + +SRDRL+GY++A+ G E+ E IVE + F ++ GY AM + Sbjct: 192 GAESIAFIGAAKEMNMSRDRLDGYKRALLAHGREVDEEIIVEQKSFTEEEGYTAMKKILE 251 Query: 240 LPNRPTALVAVDDMVSFGVLRGLNELNYKVPEDLAIVSFNNXXXXXXXXXXXXXXXXXXY 299 + P+ +V DD+++FGVL+ L E+ E +++V FNN Sbjct: 252 VKT-PSLVVTTDDLLAFGVLKLLREIG---EESISVVGFNNIPLGEYQNPPLASVDINAE 307 Query: 300 HLGYTASQVLIQSIQKPDNHDGYTNRFVIPHRLIVRES 337 LGY A+++LI S+ N + N F+I L RES Sbjct: 308 KLGYHAAKLLIDSV----NKEIEKNHFIIDTFLKERES 341 >SP2112 [K] COG1609 Transcriptional regulators Length = 328 Score = 203 bits (516), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 115/334 (34%), Positives = 189/334 (56%), Gaps = 9/334 (2%) Query: 1 MTVTIKDVAKKAGVSPSTVSRVLSGHPRISLETSRKVKEIMEEMGYTPNMMAKSLVSKTT 60 M VTIKDVAK AGVSPSTV+RV+ IS ET ++V++ M+E+ Y PN+ A+SLVS T Sbjct: 1 MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKELNYHPNLNARSLVSSYT 60 Query: 61 NSICIILPKPAEELFSNLFFMELIRGIVTQSSRSGYDVLISSGANEKEELESVSRLLKGR 120 I ++LP ++ + N FF ++RGI +S + Y + I++G +EKE L ++S+++ G+ Sbjct: 61 QVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIATGKDEKERLNAISQMVYGK 120 Query: 121 RVDGVILLYSRKDDAVIDFLESGGYPFVLVGRSDRYEDILSVDNDNIMASFDATNHLISM 180 RVDG+I LY++++D ++ + +PF+++G+S I VDNDN+ A FDAT + I Sbjct: 121 RVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKS-LSPFIPLVDNDNVQAGFDATEYFIKK 179 Query: 181 GHERIGFVSGPPNLIVSRDRLEGYRKAMANSGLEMRAEWI-VEGEFLQDSGYRAMSFFMN 239 G +RI F+ G L V++DRL GY +A+ + L I EFL++ GY+ Sbjct: 180 GCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNRIYFADEFLEEKGYKFSKRLFK 239 Query: 240 LPNRPTALVAVDDMVSFGVLRGLNELNYKVPEDLAIVSFNNXXXXXXXXXXXXXXXXXXY 299 + A++ D +++ GV + + VP ++SF++ Sbjct: 240 HDPQIDAIITTDSLLAEGVCNYIAKHQLDVP----VLSFDSVNPKLNLAAYVDINSL--- 292 Query: 300 HLGYTASQVLIQSIQKPDNHDGYTNRFVIPHRLI 333 LG + + ++Q I N+ R +I H++I Sbjct: 293 ELGRVSLETILQIINDNKNNKQICYRQLIAHKII 326 >PA1949 [K] COG1609 Transcriptional regulators Length = 337 Score = 189 bits (480), Expect = 5e-48, Method: Compositional matrix adjust. Identities = 115/336 (34%), Positives = 188/336 (55%), Gaps = 9/336 (2%) Query: 4 TIKDVAKKAGVSPSTVSRVLSGHPRISLETSRKVKEIMEEMGYTPNMMAKSLVSKTTNSI 63 T+KDVA AGVS +TVS V++ +S +KV++ + ++ Y P+ +A+SL +TT+ I Sbjct: 3 TMKDVAAMAGVSFTTVSHVVNRTRPVSDAVRKKVEDAIAQLHYVPSAVARSLKVRTTSII 62 Query: 64 CIILPKPAEELFSNLFFMELIRGIVTQSSRSGYDVLISSGANEKEELESVSRLLKGRRVD 123 +++P +N +F EL RGI R+GY V++ + + ++ + R+L+ +R+D Sbjct: 63 GLLVPNS-----TNPYFAELSRGIEDCCERNGYCVILCNSDDNPQKQANYLRVLQEKRID 117 Query: 124 GVILLYSRKDDAVIDFLESGGYPFVLVGRSDRYEDILSVDNDNIMASFDATNHLISMGHE 183 G++L + D A+ L + P V+V R + V D+ M ++ AT HL+ +GH Sbjct: 118 GLVLASAGGDGALAKGLANMRTPTVIVDREVEGVEADRVQIDHEMGAYLATRHLLELGHR 177 Query: 184 RIGFVSGPPNLIVSRDRLEGYRKAMANSGLEMRAEWIVEGEFLQDSGYR-AMSFFMNLPN 242 I + GP + VS R+EGYR+AMA +GLE+R +W++E EF GY A+ Sbjct: 178 DIACIGGPLSTKVSTLRVEGYRRAMAKAGLEVRPQWLLESEFSSPGGYHAALGLLGGEGE 237 Query: 243 RPTALVAVDDMVSFGVLRGLNELNYKVPEDLAIVSFNNXXXXXXXXXXXXXXXXXXYHLG 302 RPTA+VA +DM+ GVLR ELN +VP +L+++ F++ LG Sbjct: 238 RPTAIVAGNDMIGIGVLRAAAELNIRVPHELSVIGFDDIELSRFVFPALTTVGQSIRLLG 297 Query: 303 YTASQVLIQSIQKPDNHDGYTNRFVIPHRLIVRESS 338 A+Q+L+Q I + + R V P L++RES+ Sbjct: 298 EIAAQLLLQRIA--EREEPMQRRVVAPA-LVLREST 330 >BS_ccpA [K] COG1609 Transcriptional regulators Length = 334 Score = 182 bits (461), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 105/338 (31%), Positives = 185/338 (54%), Gaps = 11/338 (3%) Query: 3 VTIKDVAKKAGVSPSTVSRVLSGHPRISLETSRKVKEIMEEMGYTPNMMAKSLVSKTTNS 62 +TI DVA++A VS +TVSRV++G+P + T +KV E +E +GY PN +A+ L SK T + Sbjct: 4 ITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTTT 63 Query: 63 ICIILPKPAEELFSNLFFMELIRGIVTQSSRSGYDVLIS-SGANEKEELESVSRLLKGRR 121 + +I+P S++F+ EL RGI ++ Y++++S S N ++EL ++ +L G++ Sbjct: 64 VGVIIPD-----ISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTML-GKQ 117 Query: 122 VDGVILLYSRKDDAVIDFLESGGYPFVLVGRSDRYEDILSVDNDNIMASFDATNHLISMG 181 VDG++ + D + + P VL + E+ SV D A +DA L+ G Sbjct: 118 VDGIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKG 177 Query: 182 HERIGFVSGPPNLIVSRD-RLEGYRKAMANSGLEMRAEWIVEGEFLQDSGYRAMSFFMNL 240 H I FVSGP ++R +L+GY++A+ + L +++ EG++ DSG A+ M+L Sbjct: 178 HTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSL 237 Query: 241 PNRPTALVAVDDMVSFGVLRGLNELNYKVPEDLAIVSFNNXXXXXXXXXXXXXXXXXXYH 300 +PTA+++ D ++ G++ + +PEDL I+ F+N Y Sbjct: 238 DKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYD 297 Query: 301 LGYTASQVLIQSIQKPDNHDGYTNRFVIPHRLIVRESS 338 +G A ++L + + K + +PHR+ +R+S+ Sbjct: 298 IGAVAMRLLTKLMNKEPVEEHIVE---LPHRIELRKST 332 >RSc1014 [K] COG1609 Transcriptional regulators Length = 347 Score = 180 bits (457), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 112/347 (32%), Positives = 182/347 (52%), Gaps = 22/347 (6%) Query: 3 VTIKDVAKKAGVSPSTVSRVLSGHPRISLETSRKVKEIMEEMGYTPNMMAKSLVSKTTNS 62 TIKDVA AGVS +TVS V++ ++ ET ++V+E + Y P+ +A+SL +TT + Sbjct: 2 ATIKDVAALAGVSFTTVSHVINNTRPVNSETRKRVEEAIRATRYVPSAVARSLKHRTTRT 61 Query: 63 ICIILPKPAEELFSNLFFMELIRGIVTQSSRSGYDVLISSGANEKEELESVSRLLKGRRV 122 I +++P +N +F EL RGI + +GY V++ + ++ + R+L +RV Sbjct: 62 IGVLVPT-----ATNPYFAELARGIEDVCAAAGYSVILCNSDDDPRKQRDYLRVLMEKRV 116 Query: 123 DGVILLYSRKDDAVIDFLESGGYPFVLVGRSDRYEDILS--VDNDNIMASFDATNHLISM 180 DG+I+ + D+A++D L P V+V R E IL+ V D+ ++ AT HL+ + Sbjct: 117 DGLIVSSAGPDNALLDALGESALPVVMVDRPT--EGILADQVQIDHEEGAYLATRHLLEL 174 Query: 181 GHERIGFVSGPPNLIVSRDRLEGYRKAMANSGLEMRAEWIVEGEFLQDSGYRAMSFFMNL 240 GH RI +SGP L V+ RL G+ +A+ +G+ A + EG+F GYRA + Sbjct: 175 GHRRIACISGPSTLSVTAGRLAGFHRALREAGVPEHAARVAEGDFTSPGGYRAARELLTT 234 Query: 241 PNRPTALVAVDDMVSFGVLRGLNELNYKVPEDLAIVSFNNXXXXXXXXXXXXXXXXXXYH 300 PTA+ A +D++ G LR EL VP++L+I+ F++ Sbjct: 235 GETPTAIFASNDLMGIGALRAAAELGIAVPKELSIIGFDDIELSRYVYPALSTVGQSIRQ 294 Query: 301 LGYTASQVLIQSI---------QKPDNHDGYTNRFVIPHRLIVRESS 338 LG T + L++ + + PD R V+P RL +RES+ Sbjct: 295 LGETTASTLLEHLTDHAARHHHEIPDA----PRRIVLPPRLSLREST 337 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.135 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 23,306,819 Number of extensions: 877062 Number of successful extensions: 4028 Number of sequences better than 1.0e-05: 175 Number of HSP's gapped: 3692 Number of HSP's successfully gapped: 175 Length of query: 345 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 238 Effective length of database: 26,037,693 Effective search space: 6196970934 Effective search space used: 6196970934 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 116 (49.3 bits)