BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0294.0001.p (481 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2398 [P] COG4773 Outer membrane receptor for ferric coprogen a... 483 e-136 YGR101w [R] COG0705 Uncharacterized membrane protein (homolog of... 483 e-136 SPBP4H10.10 [R] COG0705 Uncharacterized membrane protein (homolo... 483 e-136 RSc2655 [R] COG0705 Uncharacterized membrane protein (homolog of... 483 e-136 AGl2465 [R] COG0705 Uncharacterized membrane protein (homolog of... 483 e-136 >PA2398 [P] COG4773 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Length = 419 Score = 483 bits (1242), Expect = e-136, Method: Compositional matrix adjust. Identities = 238/413 (57%), Positives = 315/413 (76%), Gaps = 7/413 (1%) Query: 3 LQISDLEEMKLTDLYKLAKKYQIPYYGTLKKRELIFAILRAQAEQSGLMFMEGVLEILPE 62 + +++L+ +++L L + + ++K+++IFAIL+ A+ +F +GVLEIL + Sbjct: 1 MNLTELKNTPVSELITLGENMGLENLARMRKQDIIFAILKQHAKSGEDIFGDGVLEILQD 60 Query: 63 GYGFLRPIN--YLPSAEDIYISASQIRKFDLRSGDLVSGKCRTPKENERYFGLLQVNAVN 120 G+GFLR + YL +DIY+S SQIR+F+LR+GD +SGK R PKE ERYF LL+VN VN Sbjct: 61 GFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPKEGERYFALLKVNEVN 120 Query: 121 GENPASAAERLHFPALTPLYPQDKLPLE---TSPTQLSTRIMDLLAPVGLGQRGLIVAPP 177 + P +A ++ F LTPL+ +L +E S L+ R++DL +P+G GQRGLIVAPP Sbjct: 121 FDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTARVLDLASPIGRGQRGLIVAPP 180 Query: 178 KAGKTLLLKEIANSISTNNPEIALFVLLIDERPEEVTDMQRSVKGEVVASTFDELPENHI 237 KAGKT+LL+ IA SI+ N+P+ L VLLIDERPEEVT+MQR VKGEVVASTFDE H+ Sbjct: 181 KAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHV 240 Query: 238 KVAELVLQRALRLVEHKKDVVILLDSITRLARAYNLVVPPSGRTLSGGIDPAAFHRPKRF 297 +VAE+V+++A RLVEHKKDV+ILLDSITRLARAYN VVP SG+ L+GG+D A HRPKRF Sbjct: 241 QVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRF 300 Query: 298 FGSARNVEEGGSLTILATALIDTGSRMDDIIYEEFKGTGNMELHLDRKLAERRIFPAIDI 357 FG+ARNVEEGGSLTI+ATALIDTGS+MD++IYEEFKGTGNMELHL RK+AE+R+FPAID Sbjct: 301 FGAARNVEEGGSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDY 360 Query: 358 RRSGTRREEVLLSKEELDTIWAIRKNMNE--SYDFVEGFLKKLRDSKTNAEFL 408 RSGTR+EE+L ++EEL +W +RK ++ D +E + KL +KTN +F Sbjct: 361 NRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDDFF 413 >YGR101w [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid) Length = 419 Score = 483 bits (1242), Expect = e-136, Method: Compositional matrix adjust. Identities = 238/413 (57%), Positives = 315/413 (76%), Gaps = 7/413 (1%) Query: 3 LQISDLEEMKLTDLYKLAKKYQIPYYGTLKKRELIFAILRAQAEQSGLMFMEGVLEILPE 62 + +++L+ +++L L + + ++K+++IFAIL+ A+ +F +GVLEIL + Sbjct: 1 MNLTELKNTPVSELITLGENMGLENLARMRKQDIIFAILKQHAKSGEDIFGDGVLEILQD 60 Query: 63 GYGFLRPIN--YLPSAEDIYISASQIRKFDLRSGDLVSGKCRTPKENERYFGLLQVNAVN 120 G+GFLR + YL +DIY+S SQIR+F+LR+GD +SGK R PKE ERYF LL+VN VN Sbjct: 61 GFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPKEGERYFALLKVNEVN 120 Query: 121 GENPASAAERLHFPALTPLYPQDKLPLE---TSPTQLSTRIMDLLAPVGLGQRGLIVAPP 177 + P +A ++ F LTPL+ +L +E S L+ R++DL +P+G GQRGLIVAPP Sbjct: 121 FDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTARVLDLASPIGRGQRGLIVAPP 180 Query: 178 KAGKTLLLKEIANSISTNNPEIALFVLLIDERPEEVTDMQRSVKGEVVASTFDELPENHI 237 KAGKT+LL+ IA SI+ N+P+ L VLLIDERPEEVT+MQR VKGEVVASTFDE H+ Sbjct: 181 KAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHV 240 Query: 238 KVAELVLQRALRLVEHKKDVVILLDSITRLARAYNLVVPPSGRTLSGGIDPAAFHRPKRF 297 +VAE+V+++A RLVEHKKDV+ILLDSITRLARAYN VVP SG+ L+GG+D A HRPKRF Sbjct: 241 QVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRF 300 Query: 298 FGSARNVEEGGSLTILATALIDTGSRMDDIIYEEFKGTGNMELHLDRKLAERRIFPAIDI 357 FG+ARNVEEGGSLTI+ATALIDTGS+MD++IYEEFKGTGNMELHL RK+AE+R+FPAID Sbjct: 301 FGAARNVEEGGSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDY 360 Query: 358 RRSGTRREEVLLSKEELDTIWAIRKNMNE--SYDFVEGFLKKLRDSKTNAEFL 408 RSGTR+EE+L ++EEL +W +RK ++ D +E + KL +KTN +F Sbjct: 361 NRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDDFF 413 >SPBP4H10.10 [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid) Length = 419 Score = 483 bits (1242), Expect = e-136, Method: Compositional matrix adjust. Identities = 238/413 (57%), Positives = 315/413 (76%), Gaps = 7/413 (1%) Query: 3 LQISDLEEMKLTDLYKLAKKYQIPYYGTLKKRELIFAILRAQAEQSGLMFMEGVLEILPE 62 + +++L+ +++L L + + ++K+++IFAIL+ A+ +F +GVLEIL + Sbjct: 1 MNLTELKNTPVSELITLGENMGLENLARMRKQDIIFAILKQHAKSGEDIFGDGVLEILQD 60 Query: 63 GYGFLRPIN--YLPSAEDIYISASQIRKFDLRSGDLVSGKCRTPKENERYFGLLQVNAVN 120 G+GFLR + YL +DIY+S SQIR+F+LR+GD +SGK R PKE ERYF LL+VN VN Sbjct: 61 GFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPKEGERYFALLKVNEVN 120 Query: 121 GENPASAAERLHFPALTPLYPQDKLPLE---TSPTQLSTRIMDLLAPVGLGQRGLIVAPP 177 + P +A ++ F LTPL+ +L +E S L+ R++DL +P+G GQRGLIVAPP Sbjct: 121 FDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTARVLDLASPIGRGQRGLIVAPP 180 Query: 178 KAGKTLLLKEIANSISTNNPEIALFVLLIDERPEEVTDMQRSVKGEVVASTFDELPENHI 237 KAGKT+LL+ IA SI+ N+P+ L VLLIDERPEEVT+MQR VKGEVVASTFDE H+ Sbjct: 181 KAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHV 240 Query: 238 KVAELVLQRALRLVEHKKDVVILLDSITRLARAYNLVVPPSGRTLSGGIDPAAFHRPKRF 297 +VAE+V+++A RLVEHKKDV+ILLDSITRLARAYN VVP SG+ L+GG+D A HRPKRF Sbjct: 241 QVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRF 300 Query: 298 FGSARNVEEGGSLTILATALIDTGSRMDDIIYEEFKGTGNMELHLDRKLAERRIFPAIDI 357 FG+ARNVEEGGSLTI+ATALIDTGS+MD++IYEEFKGTGNMELHL RK+AE+R+FPAID Sbjct: 301 FGAARNVEEGGSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDY 360 Query: 358 RRSGTRREEVLLSKEELDTIWAIRKNMNE--SYDFVEGFLKKLRDSKTNAEFL 408 RSGTR+EE+L ++EEL +W +RK ++ D +E + KL +KTN +F Sbjct: 361 NRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDDFF 413 >RSc2655 [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid) Length = 419 Score = 483 bits (1242), Expect = e-136, Method: Compositional matrix adjust. Identities = 238/413 (57%), Positives = 315/413 (76%), Gaps = 7/413 (1%) Query: 3 LQISDLEEMKLTDLYKLAKKYQIPYYGTLKKRELIFAILRAQAEQSGLMFMEGVLEILPE 62 + +++L+ +++L L + + ++K+++IFAIL+ A+ +F +GVLEIL + Sbjct: 1 MNLTELKNTPVSELITLGENMGLENLARMRKQDIIFAILKQHAKSGEDIFGDGVLEILQD 60 Query: 63 GYGFLRPIN--YLPSAEDIYISASQIRKFDLRSGDLVSGKCRTPKENERYFGLLQVNAVN 120 G+GFLR + YL +DIY+S SQIR+F+LR+GD +SGK R PKE ERYF LL+VN VN Sbjct: 61 GFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPKEGERYFALLKVNEVN 120 Query: 121 GENPASAAERLHFPALTPLYPQDKLPLE---TSPTQLSTRIMDLLAPVGLGQRGLIVAPP 177 + P +A ++ F LTPL+ +L +E S L+ R++DL +P+G GQRGLIVAPP Sbjct: 121 FDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTARVLDLASPIGRGQRGLIVAPP 180 Query: 178 KAGKTLLLKEIANSISTNNPEIALFVLLIDERPEEVTDMQRSVKGEVVASTFDELPENHI 237 KAGKT+LL+ IA SI+ N+P+ L VLLIDERPEEVT+MQR VKGEVVASTFDE H+ Sbjct: 181 KAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHV 240 Query: 238 KVAELVLQRALRLVEHKKDVVILLDSITRLARAYNLVVPPSGRTLSGGIDPAAFHRPKRF 297 +VAE+V+++A RLVEHKKDV+ILLDSITRLARAYN VVP SG+ L+GG+D A HRPKRF Sbjct: 241 QVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRF 300 Query: 298 FGSARNVEEGGSLTILATALIDTGSRMDDIIYEEFKGTGNMELHLDRKLAERRIFPAIDI 357 FG+ARNVEEGGSLTI+ATALIDTGS+MD++IYEEFKGTGNMELHL RK+AE+R+FPAID Sbjct: 301 FGAARNVEEGGSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDY 360 Query: 358 RRSGTRREEVLLSKEELDTIWAIRKNMNE--SYDFVEGFLKKLRDSKTNAEFL 408 RSGTR+EE+L ++EEL +W +RK ++ D +E + KL +KTN +F Sbjct: 361 NRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDDFF 413 >AGl2465 [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid) Length = 320 Score = 483 bits (1242), Expect = e-136, Method: Compositional matrix adjust. Identities = 0/413 (0%), Positives = 0/413 (0%), Gaps = 7/413 (1%) Query: 3 LQISDLEEMKLTDLYKLAKKYQIPYYGTLKKRELIFAILRAQAEQSGLMFMEGVLEILPE 62 + + + ++ + F + + ++ E Sbjct: 1 MLRLSVGKKAWHKSIMKSEHTIEATIARHAPHDGTFETQLPGLKLIRCSETTLPMPVVYE 60 Query: 63 GYGFLRPIN--YLPSAEDIYISASQIRKFDLRSGDLVSGKCRTPKENERYFGLLQVNAVN 120 L + ++ ++ K+ L ++ V Sbjct: 61 PTLCLVAQGRKQAVLGQTSFVYDPSSYLVASVDLPVMGSVIEASKDKPYLSMQLDLDTVE 120 Query: 121 GENPASAAERLHFPALTPLYPQDKLPLE---TSPTQLSTRIMDLLAPVGLGQRGLIVAPP 177 + A + ++ ++D + Sbjct: 121 LADLAIRYPSEQHAPINGPIGLLLNKVDEGIIDAASRLLALLDTPRDIDALSPLAKREIL 180 Query: 178 KAGKTLLLKEIANSISTNNPEIALFVLLIDERPEEVTDMQRSVKGEVVASTFDELPENHI 237 T + I + I + + G VA H Sbjct: 181 YRLITGVGGAALRQIVQAGAHVNQIARSIVWIRKHFRETCSVEAGAEVAGMSRSTFHAHF 240 Query: 238 KVAELVLQRALRLVEHKKDVVILLDSITRLARAYNLVVPPSGRTLSGGIDPAAFHRPKRF 297 K + R ++ L+ S A V + + F Sbjct: 241 KAVTNMSPLEFRTQLRLQEARRLMLSEGLDAATAGFQVGYASPSQFSREYGRVFGMSPAK 300 Query: 298 FGSARNVEEGGSLTILATALIDTGSRMDDIIYEEFKGTGNMELHLDRKLAERRIFPAIDI 357 Sbjct: 301 360 Query: 358 RRSGTRREEVLLSKEELDTIWAIRKNMNE--SYDFVEGFLKKLRDSKTNAEFL 408 Sbjct: 361 413 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.137 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 31,825,400 Number of extensions: 1316500 Number of successful extensions: 5292 Number of sequences better than 1.0e-05: 80 Number of HSP's gapped: 5153 Number of HSP's successfully gapped: 80 Length of query: 481 Length of database: 38,378,431 Length adjustment: 110 Effective length of query: 371 Effective length of database: 25,691,691 Effective search space: 9531617361 Effective search space used: 9531617361 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 118 (50.1 bits)