BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0290.0052.p (390 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH1343 [H] COG0635 Coproporphyrinogen III oxidase and related Fe... 340 2e-93 BS_hemN [H] COG0635 Coproporphyrinogen III oxidase and related F... 338 7e-93 CAC1279 [H] COG0635 Coproporphyrinogen III oxidase and related F... 265 1e-70 ECs3831 [H] COG0635 Coproporphyrinogen III oxidase and related F... 236 6e-62 ZyggW [H] COG0635 Coproporphyrinogen III oxidase and related Fe-... 235 7e-62 >BH1343 [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Length = 228 Score = 340 bits (873), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 0/381 (0%), Positives = 0/381 (0%), Gaps = 2/381 (0%) Query: 10 PEAVYIHIPFCTNKCFYCDFNSYVLKDQPVMDYLRALDREMEMTVKHTTPGVIKTIFVGG 69 A + + L ++ Sbjct: 2 RPAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITA 61 Query: 70 GTPTVLKPEEMAYFLKSVRTHFPQWDENIEFSMEANPGTTDKDKLAVMKEGGVNRVSFGV 129 + + ++ + + A D A+ + Sbjct: 62 EYGMLPRSTHTRNAREAAKGKQGGRTME-IQRLIARALRAAVDLKALGEFTITLDCDVLQ 120 Query: 130 QAFQNELLSGIGRIHNVDDVYRSLENARSVGLHNLSVDLMFGLPNQTVDMLRESVSKALE 189 S G + D + L + + + + + + Sbjct: 121 ADGGTRTASITGACVALVDALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAVCDLEYVED 180 Query: 190 LNLPHYSIYSLKVEENTLFHTLFNKNKLPLPSXXXXXXXXXXXXSTMEAAGYGQYEISNF 249 Sbjct: 181 240 Query: 250 AKPGMESRHNITYWRNEDYYGLGAGAHGYVKRQRHMNIKGVNPYIEASHSG-LPRLDTFR 308 Sbjct: 241 300 Query: 309 ISEQEAMEDFMMVGLRMREGVSDQAFRAQFGKSLQDIFAGSLKKMLAAGLIEQNGDAYRL 368 Sbjct: 301 360 Query: 369 SKQGILFGNDVFGEFVGVLTE 389 Sbjct: 361 381 >BS_hemN [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Length = 228 Score = 338 bits (868), Expect = 7e-93, Method: Compositional matrix adjust. Identities = 0/363 (0%), Positives = 0/363 (0%), Gaps = 1/363 (0%) Query: 11 EAVYIHIPFCTNKCFYCDFNSYVLKDQPVMDYLRALDREMEMTVKHTTPGVIKTIFVGGG 70 ++ + V + + + Sbjct: 2 RPAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITA 61 Query: 71 TPTVLKPEEMAYFLKSVRTHFPQWDENIEFSMEANPGTTDKDKLAVMKEGGVNRVSFGVQ 130 +L + + A D A+ + Sbjct: 62 EYGMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQA 121 Query: 131 AFQNELLSGIGRIHNVDDVYRSLENARSVGLHNLSVDLMFGLPNQTVDMLRESVSKALEL 190 S G + D + L + + + + + + Sbjct: 122 DGGTRTASITGACVALVDALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAVCDLEYVEDS 181 Query: 191 NLPHYSIYSLKVEENTLFHTLFNKNKLPLPSXXXXXXXXXXXXSTMEAAGYGQYEISNFA 250 Sbjct: 182 241 Query: 251 KPGMESRHNITYWRNEDYYGLGAGAHGYVKRQRHMNIKGVNPYIE-ASHSGLPRLDTFRI 309 Sbjct: 242 301 Query: 310 SEQEAMEDFMMVGLRMREGVSDQAFRAQFGKSLQDIFAGSLKKMLAAGLIEQNGDAYRLS 369 Sbjct: 302 361 Query: 370 KQG 372 Sbjct: 362 364 >CAC1279 [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Length = 228 Score = 265 bits (676), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 0/377 (0%), Positives = 0/377 (0%), Gaps = 12/377 (3%) Query: 12 AVYIHIPFCTNKCFYCDFNSYVLKDQPVMDYLRALDREMEMTVKHTTPGVIKTIFVGGGT 71 + ++ D +E + + Sbjct: 5 GRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIE---EGVPRFLKGQGQGWITA 61 Query: 72 PTVLKPEEMAYF---LKSVRTHFPQWDENIEFSMEANPGTTDKDKLAVMKEGGVNRVSFG 128 + P + ++ + + + G Sbjct: 62 EYGMLPRSTHTRNAREAAKGK-----QGGRTMEIQRLIARALRAAVDLKALGEFTITLDC 116 Query: 129 VQAFQNELLSGIGRIHNVDDVYRSLENARSVGLHNLSVDLMFGLPNQTVDMLRESVSKAL 188 + + +L+ G + + E+V Sbjct: 117 DVLQADGGTRTASITGACVALVDALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAVCDLE 176 Query: 189 ELNLPHYSIYSLKVEENTLFHTLFNKNKLPLPSXXXXXXXXXXXXSTMEAAGYGQYEISN 248 Sbjct: 177 236 Query: 249 FAKPGMESRHNITYWRNEDYYGLGAGAHGYVKRQRHMNIKGVNPYIEASHSGLPRL-DTF 307 Sbjct: 237 296 Query: 308 RISEQEAMEDFMMVGLRMREGVSDQAFRAQFGKSLQDIFAGSLKKMLAAGLIEQNGDAYR 367 Sbjct: 297 356 Query: 368 LSKQGILFGNDVFGEFV 384 Sbjct: 357 373 >ECs3831 [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Length = 228 Score = 236 bits (601), Expect = 6e-62, Method: Compositional matrix adjust. Identities = 0/389 (0%), Positives = 0/389 (0%), Gaps = 28/389 (7%) Query: 9 PPEAVYIHIPFCTNKCFYCDFNSYVLKDQ-PVMDYLRALDREMEMTVKHTTPGVIKTIFV 67 + T S +++ + +++ + +K G I + Sbjct: 5 GRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAEYG 64 Query: 68 GGGTPTVLKPEEMAYFLKSVRTHFPQWDENIEFSMEANPGTTDKDKLAVMKEGGVNRVSF 127 T + A K I ++ A + + + V + Sbjct: 65 MLPRSTHTRNAREAAKGKQGGRTME-IQRLIARALRAAVDLKALGEFTITLDCDVLQADG 123 Query: 128 GVQAFQNELLSGIGRIHNVDDVYRSLENARSVGLHNLSVDLMFGLPNQTVDMLRESVSKA 187 G + V + +V + D+ S A Sbjct: 124 GTRTASITGACVALVDALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAVCDLEYVEDSAA 183 Query: 188 LELNLPHYSIYSLKVEENTLFHTLFNKNKLP-LPSXXXXXXXXXXXXSTMEAAGYGQYEI 246 + +E + + Sbjct: 184 ETDMNVVMTEDGRIIEVQGTA-----EGEPFT 238 Query: 247 SNFAKPGMESRHNITYWRNEDYYGLGAGAHGYV----------KRQRHMNIKGVNPYIEA 296 Sbjct: 239 298 Query: 297 SHSGLPRLDTFRISEQEAMEDFMMVGLRMREGVSDQAFRAQFGKSLQDIFAGSLKKMLAA 356 Sbjct: 299 ---------- 348 Query: 357 GLIEQNGDAYRLSKQGILFGNDVFGEFVG 385 Sbjct: 349 377 >ZyggW [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Length = 228 Score = 235 bits (600), Expect = 7e-62, Method: Compositional matrix adjust. Identities = 0/389 (0%), Positives = 0/389 (0%), Gaps = 28/389 (7%) Query: 9 PPEAVYIHIPFCTNKCFYCDFNSYVLKDQ-PVMDYLRALDREMEMTVKHTTPGVIKTIFV 67 + T S +++ + +++ + +K G I + Sbjct: 5 GRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAEYG 64 Query: 68 GGGTPTVLKPEEMAYFLKSVRTHFPQWDENIEFSMEANPGTTDKDKLAVMKEGGVNRVSF 127 T + A K I ++ A + + + V + Sbjct: 65 MLPRSTHTRNAREAAKGKQGGRTME-IQRLIARALRAAVDLKALGEFTITLDCDVLQADG 123 Query: 128 GVQAFQNELLSGIGRIHNVDDVYRSLENARSVGLHNLSVDLMFGLPNQTVDMLRESVSKA 187 G + V + +V + D+ S A Sbjct: 124 GTRTASITGACVALVDALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAVCDLEYVEDSAA 183 Query: 188 LELNLPHYSIYSLKVEENTLFHTLFNKNKLP-LPSXXXXXXXXXXXXSTMEAAGYGQYEI 246 + +E + + Sbjct: 184 ETDMNVVMTEDGRIIEVQGTA-----EGEPFT 238 Query: 247 SNFAKPGMESRHNITYWRNEDYYGLGAGAHGYV----------KRQRHMNIKGVNPYIEA 296 Sbjct: 239 298 Query: 297 SHSGLPRLDTFRISEQEAMEDFMMVGLRMREGVSDQAFRAQFGKSLQDIFAGSLKKMLAA 356 Sbjct: 299 ---------- 348 Query: 357 GLIEQNGDAYRLSKQGILFGNDVFGEFVG 385 Sbjct: 349 377 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.137 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 29,274,531 Number of extensions: 1223600 Number of successful extensions: 2300 Number of sequences better than 1.0e-05: 72 Number of HSP's gapped: 2118 Number of HSP's successfully gapped: 72 Length of query: 390 Length of database: 38,378,431 Length adjustment: 108 Effective length of query: 282 Effective length of database: 25,922,359 Effective search space: 7310105238 Effective search space used: 7310105238 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 117 (49.7 bits)