BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0290.0039.p (317 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_kdgK [G] COG0524 Sugar kinases, ribokinase family 380 e-105 CAC0395 [G] COG0524 Sugar kinases, ribokinase family 318 1e-86 PA2261 [G] COG0524 Sugar kinases, ribokinase family 296 4e-80 L0021 [G] COG0524 Sugar kinases, ribokinase family 279 4e-75 ML0021 [T] COG1716 FOG: FHA domain 279 4e-75 >BS_kdgK [G] COG0524 Sugar kinases, ribokinase family Length = 324 Score = 380 bits (975), Expect = e-105, Method: Compositional matrix adjust. Identities = 185/311 (59%), Positives = 231/311 (74%), Gaps = 2/311 (0%) Query: 4 QLDAVTFGEPMAMFYANEAGPLHEVTSFSKALAGAESNVATGLSRLGHKTGYVTKLGEDN 63 +LDAVTFGE MAMFYANE G LHEV++FSK LAGAESNVA GL+RLG + G+++K+G D Sbjct: 2 KLDAVTFGESMAMFYANEYGGLHEVSTFSKGLAGAESNVACGLARLGFRMGWMSKVGNDQ 61 Query: 64 FGQFIASALNKEQINTDSITYTK-EFPTGMLIKSKVLTGDPKVEYFRKNSAASKLSLSDF 122 G FI L KE ++ + ++ E PTG+L+KSKV GDP+V Y+RKNSAAS L+ +++ Sbjct: 62 LGTFILQELKKEGVDVSRVIRSQDENPTGLLLKSKVKEGDPQVTYYRKNSAASTLTTAEY 121 Query: 123 DESYFASAGHLHVTSISAALSKTCHEFSLHAMEFMKKNGKTVSLDPNLRPVLWPDTETMV 182 YF AGHLHVT I ALS +F+ H M M+ GKT+S DPN+RP LWPD TMV Sbjct: 122 PRDYFQCAGHLHVTGIPPALSAEMKDFTYHVMNDMRNAGKTISFDPNVRPSLWPDQATMV 181 Query: 183 NTINDLAARCDWFLPGHSEGKTLTGLDTPEEIAGYYLERGVSLVVIKLGPEGAYYKTSSG 242 +TINDLA DWF PG +EG+ LTG TPE IA YYL++G S V IKLG EGAY+KT + Sbjct: 182 HTINDLAGLADWFFPGIAEGELLTGEKTPEGIADYYLKKGASFVAIKLGKEGAYFKTGT- 240 Query: 243 EEGYVSGFKVETVVDTVGAGDGFAVGVISAMLEKLTVAEAVKRGNAIGALAVMSPGDMDG 302 EG++ G +V+ VVDTVGAGDGFAVGVIS +L+ L+ +AV+RGNAIGAL V +PGDMDG Sbjct: 241 SEGFLEGCRVDRVVDTVGAGDGFAVGVISGILDGLSYKDAVQRGNAIGALQVQAPGDMDG 300 Query: 303 LPDRDSLEKFM 313 LP R+ L F+ Sbjct: 301 LPTREKLASFL 311 >CAC0395 [G] COG0524 Sugar kinases, ribokinase family Length = 315 Score = 318 bits (814), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 166/311 (53%), Positives = 210/311 (67%), Gaps = 7/311 (2%) Query: 8 VTFGEPMAMFYANEAGPLH----EVTSFSKALAGAESNVATGLSRLGHKTGYVTKLGEDN 63 +T GEP+A+F A + EV F K LAGAE NV+ G+SRLGH Y+TKLGED Sbjct: 5 ITIGEPLALFAAEGESEIDKRISEVDHFKKFLAGAEVNVSVGVSRLGHSAQYITKLGEDP 64 Query: 64 FGQFIASALNKEQINTDSITYTKEFPTGMLIKSKVLTGDPKVEYFRKNSAASKLSLSDFD 123 FG+FI LN+E + TD I+ T + TG +KSKV GDP + YFRKNSAA+ S+ D + Sbjct: 65 FGEFIRRRLNEENVGTDYISSTNKKFTGFQLKSKVSEGDPSIFYFRKNSAAANFSVEDLN 124 Query: 124 ESYFASAGHLHVTSISAALSKTCHEFSLHAMEFMKKNGKTVSLDPNLRPVLWPDTETMVN 183 + H+H+T I ALS++ E + +E K+ T + D NLRP LW E M++ Sbjct: 125 KVNLDGVKHVHITGIFPALSESTKEATYKLLELAKERNITTTFDTNLRPQLWNSKEDMIS 184 Query: 184 TINDLAARCDWFLPGHSEGKTLTGLDTPEEIAGYYLERGVSLVVIKLGPEGAYYKTSSGE 243 TIND+A + D LPG +EG L G D PEEIA +YL +GV LV+IKLG +GAY KT + Sbjct: 185 TINDIAFKSDILLPGINEGLVLMGSDKPEEIADFYLNKGVKLVIIKLGSKGAYVKTK--D 242 Query: 244 EGY-VSGFKVETVVDTVGAGDGFAVGVISAMLEKLTVAEAVKRGNAIGALAVMSPGDMDG 302 E Y V GFKV+ VVDTVGAGDGFAVGVISA+LE ++V EAV+RGNA+GALAVMS GD DG Sbjct: 243 EAYTVEGFKVKHVVDTVGAGDGFAVGVISAILEGISVKEAVRRGNAVGALAVMSEGDNDG 302 Query: 303 LPDRDSLEKFM 313 P + LEKF+ Sbjct: 303 YPTHEELEKFL 313 >PA2261 [G] COG0524 Sugar kinases, ribokinase family Length = 316 Score = 296 bits (757), Expect = 4e-80, Method: Compositional matrix adjust. Identities = 150/303 (49%), Positives = 195/303 (64%), Gaps = 3/303 (0%) Query: 8 VTFGEPMAMFYANEAGPLHEVTSFSKALAGAESNVATGLSRLGHKTGYVTKLGEDNFGQF 67 + FGE MAMF A + G L V F K +AGA+SNVA GL+RLG +++++G+D+ G+F Sbjct: 7 LCFGETMAMFVAEQPGELDRVEQFGKRIAGADSNVAIGLARLGFAVAWLSRVGDDSLGRF 66 Query: 68 IASALNKEQINTDSITYTKEFPTGMLIKSKVLTG-DPKVEYFRKNSAASKLSLSDFDESY 126 + +L +E ++ + + PTG +KS+ + G DP+VEYFR+ SAAS+L L+ E Sbjct: 67 VLDSLTREGLDCRFVEVDAQAPTGFQMKSREVDGADPRVEYFRRGSAASRLGLAHIREEM 126 Query: 127 FASAGHLHVTSISAALSKTCHEFSLHAMEFMKKNGKTVSLDPNLRPVLWPDTETMVNTIN 186 A HLH T I ALS + E S M M+ G ++S DPNLRP LWP M+ IN Sbjct: 127 LG-ARHLHATGIPPALSASACELSHELMRRMRGKGASLSFDPNLRPSLWPSERRMIAEIN 185 Query: 187 DLAARCDWFLPGHSEGKTLTGLDTPEEIAGYYLERGVSLVVIKLGPEGAYYKTSSGEEGY 246 LAA W LPG EG+ L+G P +IA +YL+ GV V IKLGP GAYY+ + G EG Sbjct: 186 ALAAHAHWVLPGLEEGRLLSGWQEPADIAAFYLDMGVDAVAIKLGPSGAYYRDAHG-EGL 244 Query: 247 VSGFKVETVVDTVGAGDGFAVGVISAMLEKLTVAEAVKRGNAIGALAVMSPGDMDGLPDR 306 V G V TVVDTVGAGDGFAVGV+SA+LE L + +AV RGN IG+ AV GDM+GLP R Sbjct: 245 VPGVPVATVVDTVGAGDGFAVGVVSALLEGLPLPDAVARGNWIGSRAVQVRGDMEGLPKR 304 Query: 307 DSL 309 L Sbjct: 305 SQL 307 >L0021 [G] COG0524 Sugar kinases, ribokinase family Length = 316 Score = 279 bits (714), Expect = 4e-75, Method: Compositional matrix adjust. Identities = 152/311 (48%), Positives = 204/311 (65%), Gaps = 5/311 (1%) Query: 8 VTFGEPMAMFYA-NEAGPLHEVTSFSKALAGAESNVATGLSRLGHKTGYVTKLGEDNFGQ 66 +T GEP+ + + N+ L FSK LAGAE NVA GLSRLGHK Y++K+GED+FG Sbjct: 5 ITLGEPLVVLASENQDISLDVAEHFSKYLAGAELNVAIGLSRLGHKGIYLSKVGEDSFGN 64 Query: 67 FIASALNKEQINTDSITYTKEFPTGMLIKSKVLTGDPKVEYFRKNSAASKLSLSDFDESY 126 FI ++ K +I T +T K + TG +K KV GDPKV+Y+RKNSAA+ LS+++ Sbjct: 65 FIIESVKKAEIETTYLTKDKNYSTGFYLKQKVSEGDPKVDYYRKNSAAANLSIAELKALD 124 Query: 127 FASAGHLHVTSISAALSKT-CHEFSLHAMEFMKKNGKTVSLDPNLRPVLWPDTETMVNTI 185 + H++ I ALS+T F + + + T+ DPNLRPVLW + E M+ TI Sbjct: 125 LSGIKIAHLSGIFPALSETSLKTFQAFNQKLNEADILTI-FDPNLRPVLWDNQEKMIRTI 183 Query: 186 NDLAARCDWFLPGHSEGKTLTGLDTPEEIAGYYLERG--VSLVVIKLGPEGAYYKTSSGE 243 NDLA + LPG +EG+ LTG PE+IA +YLE+ +VV+KLG +GA+ K +GE Sbjct: 184 NDLAKQSQIILPGINEGEILTGSSEPEKIANFYLEQSPLTKIVVVKLGADGAFVKLKNGE 243 Query: 244 EGYVSGFKVETVVDTVGAGDGFAVGVISAMLEKLTVAEAVKRGNAIGALAVMSPGDMDGL 303 + +VSGFKV VVDTVGAGDGFAVG+ SA+LE T+ EAVKR A+GALAV S GD +G Sbjct: 244 QYFVSGFKVAKVVDTVGAGDGFAVGLESALLEGKTLKEAVKRACAVGALAVQSSGDSEGY 303 Query: 304 PDRDSLEKFMK 314 P ++ L+ F K Sbjct: 304 PTKEELKAFYK 314 >ML0021 [T] COG1716 FOG: FHA domain Length = 316 Score = 279 bits (714), Expect = 4e-75, Method: Compositional matrix adjust. Identities = 152/311 (48%), Positives = 204/311 (65%), Gaps = 5/311 (1%) Query: 8 VTFGEPMAMFYA-NEAGPLHEVTSFSKALAGAESNVATGLSRLGHKTGYVTKLGEDNFGQ 66 +T GEP+ + + N+ L FSK LAGAE NVA GLSRLGHK Y++K+GED+FG Sbjct: 5 ITLGEPLVVLASENQDISLDVAEHFSKYLAGAELNVAIGLSRLGHKGIYLSKVGEDSFGN 64 Query: 67 FIASALNKEQINTDSITYTKEFPTGMLIKSKVLTGDPKVEYFRKNSAASKLSLSDFDESY 126 FI ++ K +I T +T K + TG +K KV GDPKV+Y+RKNSAA+ LS+++ Sbjct: 65 FIIESVKKAEIETTYLTKDKNYSTGFYLKQKVSEGDPKVDYYRKNSAAANLSIAELKALD 124 Query: 127 FASAGHLHVTSISAALSKT-CHEFSLHAMEFMKKNGKTVSLDPNLRPVLWPDTETMVNTI 185 + H++ I ALS+T F + + + T+ DPNLRPVLW + E M+ TI Sbjct: 125 LSGIKIAHLSGIFPALSETSLKTFQAFNQKLNEADILTI-FDPNLRPVLWDNQEKMIRTI 183 Query: 186 NDLAARCDWFLPGHSEGKTLTGLDTPEEIAGYYLERG--VSLVVIKLGPEGAYYKTSSGE 243 NDLA + LPG +EG+ LTG PE+IA +YLE+ +VV+KLG +GA+ K +GE Sbjct: 184 NDLAKQSQIILPGINEGEILTGSSEPEKIANFYLEQSPLTKIVVVKLGADGAFVKLKNGE 243 Query: 244 EGYVSGFKVETVVDTVGAGDGFAVGVISAMLEKLTVAEAVKRGNAIGALAVMSPGDMDGL 303 + +VSGFKV VVDTVGAGDGFAVG+ SA+LE T+ EAVKR A+GALAV S GD +G Sbjct: 244 QYFVSGFKVAKVVDTVGAGDGFAVGLESALLEGKTLKEAVKRACAVGALAVQSSGDSEGY 303 Query: 304 PDRDSLEKFMK 314 P ++ L+ F K Sbjct: 304 PTKEELKAFYK 314 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.314 0.131 0.373 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 23,019,521 Number of extensions: 936477 Number of successful extensions: 2057 Number of sequences better than 1.0e-05: 107 Number of HSP's gapped: 1915 Number of HSP's successfully gapped: 107 Length of query: 317 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 211 Effective length of database: 26,153,027 Effective search space: 5518288697 Effective search space used: 5518288697 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 116 (49.3 bits)