BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0290.0038.p (359 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA1949 [K] COG1609 Transcriptional regulators 179 6e-45 CAC0393 [K] COG1609 Transcriptional regulators 177 2e-44 VC2677 [K] COG1609 Transcriptional regulators 168 1e-41 SPy0627 [K] COG1609 Transcriptional regulators 167 2e-41 BS_kdgR [K] COG1609 Transcriptional regulators 167 3e-41 >PA1949 [K] COG1609 Transcriptional regulators Length = 337 Score = 179 bits (454), Expect = 6e-45, Method: Compositional matrix adjust. Identities = 120/339 (35%), Positives = 190/339 (56%), Gaps = 13/339 (3%) Query: 23 TIEDVAQKAGVSKSTVSQFLNKRFKYMSEATKNRIAEVIEELNYQPNGLARSLKQNRTHM 82 T++DVA AGVS +TVS +N R + +S+A + ++ + I +L+Y P+ +ARSLK T + Sbjct: 3 TMKDVAAMAGVSFTTVSHVVN-RTRPVSDAVRKKVEDAIAQLHYVPSAVARSLKVRTTSI 61 Query: 83 VGIIVANIDYSLSVQCIRAIENELQRHGIQVIICNSDENADKENTHVEALVARQVDGLII 142 +G++V N + R IE+ +R+G VI+CNSD+N K+ ++ L +++DGL++ Sbjct: 62 IGLLVPNSTNPYFAELSRGIEDCCERNGYCVILCNSDDNPQKQANYLRVLQEKRIDGLVL 121 Query: 143 FPAGDNPSPYSRLIEAEYPLVFMDRLVEGITTQSLLLDNEMAVKTAIKELTGKGHEAIAI 202 AG + + L P V +DR VEG+ + +D+EM A + L GH IA Sbjct: 122 ASAGGDGALAKGLANMRTPTVIVDREVEGVEADRVQIDHEMGAYLATRHLLELGHRDIAC 181 Query: 203 LSLPLGEHAITPRKERMSGYKKAMEEAGLAMNDRYVR----SVPREAIASALDELLILPQ 258 + PL T R E GY++AM +AGL + +++ S P +AL L + Sbjct: 182 IGGPLSTKVSTLRVE---GYRRAMAKAGLEVRPQWLLESEFSSP-GGYHAALGLLGGEGE 237 Query: 259 PPTALLAANDLVLGEILKYANRHSITIPGQLSVIGIDDAEFARIYNPAITTIRQPAYEMG 318 PTA++A ND++ +L+ A +I +P +LSVIG DD E +R PA+TT+ Q +G Sbjct: 238 RPTAIVAGNDMIGIGVLRAAAELNIRVPHELSVIGFDDIELSRFVFPALTTVGQSIRLLG 297 Query: 319 MQAAKIMLSLIEAQEAAVPITYR-FPPALQQGQSVQAPP 356 AA+++L I +E P+ R PAL +S APP Sbjct: 298 EIAAQLLLQRIAEREE--PMQRRVVAPALVLREST-APP 333 >CAC0393 [K] COG1609 Transcriptional regulators Length = 344 Score = 177 bits (449), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 108/317 (34%), Positives = 174/317 (54%), Gaps = 8/317 (2%) Query: 20 KKLTIEDVAQKAGVSKSTVSQFLNKRFKYMSEATKNRIAEVIEELNYQPNGLARSLKQNR 79 KK+ I+DVA+ AGVSK+T+S++LN +F+YMSE TK+RI E IEELNY+PN +ARSLK N+ Sbjct: 5 KKVVIDDVAKLAGVSKATISRYLNGKFEYMSEKTKDRIKESIEELNYRPNNIARSLKSNK 64 Query: 80 THMVGIIVANIDYSLSVQCIRAIENELQRHGIQVIICNSDENADKENTHVEALVARQVDG 139 + ++G+++A++ S I+ I +E + G ++I NSD + +E ++++L+ ++V+G Sbjct: 65 SKLIGVVIADLTNPFSSIIIKGIGDECKARGYNMVIANSDNDVKQEEEYIKSLLDQRVEG 124 Query: 140 LIIFPAGDNPSPYSRLIEAEYPLVFMDRLVEGITTQSLLLDNEMAVKTAIKELTGKGHEA 199 +I+ G N + E P+ +DR S+ +N I L G + Sbjct: 125 IIVNSTGYNEEFLLSIKERGIPVSMVDRTFCEDKVDSVKSNNYDITVETINYLIDAGFNS 184 Query: 200 IAILSLPLGEHAITPRKERMSGYKKAMEEAGLAMNDRYVRSVPREAIASALD----ELLI 255 + + L I PR ER + + + Y SV + A L+ + L Sbjct: 185 LCFFTERLDN--IKPRIERERAFIDVCSKR--LKKENYNISVVDYSKAGNLEVNIYKFLN 240 Query: 256 LPQPPTALLAANDLVLGEILKYANRHSITIPGQLSVIGIDDAEFARIYNPAITTIRQPAY 315 A+ A N +VL L N+ +I +P L + G D+ +A + P ITTI QP+Y Sbjct: 241 NYSGKKAIFAVNGVVLLHTLSAINKLNINVPKDLGICGYDNWGWAALIPPGITTISQPSY 300 Query: 316 EMGMQAAKIMLSLIEAQ 332 EMG +AAK++L IE + Sbjct: 301 EMGSEAAKLVLDRIEGK 317 >VC2677 [K] COG1609 Transcriptional regulators Length = 335 Score = 168 bits (426), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 109/314 (34%), Positives = 172/314 (54%), Gaps = 8/314 (2%) Query: 23 TIEDVAQKAGVSKSTVSQFLNKRFKYMSEATKNRIAEVIEELNYQPNGLARSLKQNRTHM 82 T++DVAQ AGVS +TVS+ L K +S +T+ R+ E + E Y PN LAR+L++N + Sbjct: 3 TMKDVAQLAGVSTATVSRALMNPEK-VSSSTRKRVEEAVLEAGYSPNSLARNLRRNESKT 61 Query: 83 VGIIVANIDYSLSVQCIRAIENELQRHGIQVIICNSDENADKENTHVEALVARQVDGLII 142 + IV +I + IR IE+ HG V++ +S + +EN+ V + +Q DG+++ Sbjct: 62 IVAIVPDICDPYFSEIIRGIEDAAMEHGYLVLLGDSGQQKRRENSFVNLVFTKQADGMLL 121 Query: 143 FPAGDNPSPYSRLIEAEYP-LVFMDRLVEGITTQSLLLDNEMAVKTAIKELTGKGHEAIA 201 D P S+ + P +V + ++ +DN + A+ LT GH+ IA Sbjct: 122 L-GTDLPFDVSKPEQKNLPPMVMACEFAPELELPTVHIDNLTSAFEAVNYLTQLGHKRIA 180 Query: 202 ILSLPLGEHAITPRKERMSGYKKAMEEAGLAMNDRYVR--SVPREAIASALDELLILPQP 259 +S P +HA + R GY++A+ AG+ MN Y EA A A+ +LL LP+ Sbjct: 181 QISGP--QHAALC-QFRHQGYQQALRRAGITMNPTYCTFGDFTFEAGAKAVRQLLALPEQ 237 Query: 260 PTALLAANDLVLGEILKYANRHSITIPGQLSVIGIDDAEFARIYNPAITTIRQPAYEMGM 319 PTA+ ND + ++ A R + +P LSV+G DD +FA+ +P +TTI QP YE+G Sbjct: 238 PTAIFCHNDTMAIGAIQEAKRLGLRVPQDLSVVGFDDIQFAQYCDPPLTTISQPRYEIGR 297 Query: 320 QAAKIMLSLIEAQE 333 QA +ML L+ + Sbjct: 298 QAMLMMLELLRGHD 311 >SPy0627 [K] COG1609 Transcriptional regulators Length = 331 Score = 167 bits (423), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 114/325 (35%), Positives = 176/325 (54%), Gaps = 14/325 (4%) Query: 20 KKLTIEDVAQKAGVSKSTVSQFLNKRFKYMSEATKNRIAEVIEELNYQPNGLARSLKQNR 79 +K+TI+D+A+ A SK+TVS +LN RF MSE TKNRI+E I+ NY+P+ ARSL Sbjct: 3 RKVTIKDIAELAKTSKTTVSFYLNGRFDKMSEETKNRISESIKATNYKPSIAARSLNAKS 62 Query: 80 THMVGIIVANIDYSLSVQCIRAIENELQRHGIQVIICNSDENADKENTHVEALVARQVDG 139 T ++G+++ +I S S Q ++ IE++ Q G Q+II NS+ + +E+ +E ++ VDG Sbjct: 63 TKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSNYDPSREDELIEKMLNLGVDG 122 Query: 140 LIIFPAGDNPSPYSRLIE-AEYPLVFMDRLVEGITTQSLLLDNEMAVKTAIKELTGKGHE 198 II P N YSR+I+ + +VF D + T + +N AV I++ KG+E Sbjct: 123 FIIQPTS-NFRKYSRIIDIKKKKVVFFDSQLYEHRTNWVKTNNYDAVYDTIQQCIDKGYE 181 Query: 199 A-IAILSLPLGEHAITPRKERMSGYKKAMEEAGLAMNDRYV--RSVPREAIASALDELLI 255 I I P + ++ R ER SG+ +E L + + EAIA L L Sbjct: 182 HFIMITGNP---NLLSTRIERASGFIDVLEANHLTHQEMIIDENQTSSEAIAQFLQGSLT 238 Query: 256 LPQPPTALLAANDLVLGEILKYANRHSITIPGQLSVIGIDDAEFARIYNPAITTIRQPAY 315 + + N L ++ IP ++ ++G D+ E+ + +P +TTI QPAY Sbjct: 239 ---KKSLVFVPNCWALPKVFTAMKSLKFNIP-EIGLVGFDNIEWTKFSSPTLTTIIQPAY 294 Query: 316 EMGMQAAKIMLSLIE--AQEAAVPI 338 E G QA KI++ IE +QEA I Sbjct: 295 EEGEQATKILIDDIEGHSQEAKQQI 319 >BS_kdgR [K] COG1609 Transcriptional regulators Length = 339 Score = 167 bits (422), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 94/316 (29%), Positives = 173/316 (54%), Gaps = 5/316 (1%) Query: 23 TIEDVAQKAGVSKSTVSQFLNKRFKYMSEATKNRIAEVIEELNYQPNGLARSLKQNRTHM 82 TI+DVA+ AGVSKSTVS+++N + +S I + I ELNY+P+ +A+ LK ++ + Sbjct: 10 TIKDVAECAGVSKSTVSRYINGKIDAISPEKVKNIKKAIAELNYRPSKMAQGLKIKKSKL 69 Query: 83 VGIIVANIDYSLSVQCIRAIENELQRHGIQVIICNSDENADKENTHVEALVARQVDGLII 142 +G +VA+I SV R +E ++G +++CN+D + +KE + L A V+GLI+ Sbjct: 70 IGFVVADITNPFSVAAFRGVEEVCDQYGYSIMVCNTDNSPEKEREMLLKLEAHSVEGLIL 129 Query: 143 FPAGDNPSPYSRLIEAEYPLVFMDRLVEGITTQSLLLDNEMAVKTAIKELTGKGHEAIAI 202 G+N E + P + +DR + + ++ DN K ++++ KG+ +A+ Sbjct: 130 NATGENKDVLRAFAEQQIPTILIDRKLPDLKLDTVTTDNRWITKEILQKVYSKGYTDVAL 189 Query: 203 LSLPLGEHAITPRKERMSGYKK--AMEEAGLAMNDRYVRSVPREAIASALDELLI-LPQP 259 + P+ +I+PR ER + Y++ +++ + + +E + + L +P+ Sbjct: 190 FTEPIS--SISPRAERAAVYQEMASVQNVNGLVRLHEIDVKDKEQLKAELRSFHKEMPEQ 247 Query: 260 PTALLAANDLVLGEILKYANRHSITIPGQLSVIGIDDAEFARIYNPAITTIRQPAYEMGM 319 A+LA N L++ +I+ + IP + + G DD E+ ++ P ITTI QP+++MG Sbjct: 248 KKAILALNGLIMLKIISCMEELGLRIPQDIGIAGFDDTEWYKLIGPGITTIAQPSHDMGR 307 Query: 320 QAAKIMLSLIEAQEAA 335 A + +L IE + A Sbjct: 308 TAMERVLKRIEGDKGA 323 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.133 0.371 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 25,368,501 Number of extensions: 1002274 Number of successful extensions: 12640 Number of sequences better than 1.0e-05: 169 Number of HSP's gapped: 12269 Number of HSP's successfully gapped: 169 Length of query: 359 Length of database: 38,378,431 Length adjustment: 108 Effective length of query: 251 Effective length of database: 25,922,359 Effective search space: 6506512109 Effective search space used: 6506512109 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 116 (49.3 bits)