BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0290.0013.p (535 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SPy1587 [T] COG4753 Response regulator containing CheY-like rece... 105 2e-22 BH0793 [T] COG4753 Response regulator containing CheY-like recei... 104 4e-22 BH1910 [T] COG4753 Response regulator containing CheY-like recei... 91 5e-18 BH2109 [T] COG4753 Response regulator containing CheY-like recei... 88 3e-17 SPy1556 [T] COG4753 Response regulator containing CheY-like rece... 87 1e-16 >SPy1587 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 494 Score = 105 bits (263), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 47/126 (37%), Positives = 85/126 (67%) Query: 1 MHQILLVDDEPYVVDDLSISLPWAELGFEQVHKAYSGYEALELLQRHPIDIVVTDINMPE 60 M+++LLVDDE ++ L++ + W LGFE V A SG EAL L ++P+D++++D+ MP Sbjct: 1 MYKVLLVDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALAYLTQYPVDVMISDVTMPG 60 Query: 61 ISGIELIAAIRSRWKHIRVVMLTGYAEFEYARKAIEEQASAYLLKPIANDQLIAVIVKLR 120 ++G++LI A ++ ++ ++L+GY EF Y +KA+E + YLLKP+ +L A + + + Sbjct: 61 MTGLDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGYLLKPVDKAELQAKMKQFK 120 Query: 121 EELRSE 126 + L ++ Sbjct: 121 DWLDAQ 126 Score = 83.2 bits (204), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 36/85 (42%), Positives = 61/85 (71%) Query: 449 VSLQAIADHVQMHPVYLSKMYKLETGKRISDYISQAKMEKAAYLLIHTPLKIYEVSAELG 508 ++L+AIAD + ++ VYL + +K ET + + Y++ +++KA LL++T I E++ E G Sbjct: 398 LTLKAIADRLHVNGVYLGQCFKNETERSFTQYLNHVRIQKAQQLLLYTNQSINEIAYETG 457 Query: 509 YSNAHYFIKLFKEYSGMTPHEFRDR 533 Y+ HYFIK+FK+ +G++P EFRDR Sbjct: 458 YNTNHYFIKMFKKLNGLSPKEFRDR 482 >BH0793 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 508 Score = 104 bits (259), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 49/123 (39%), Positives = 82/123 (66%) Query: 1 MHQILLVDDEPYVVDDLSISLPWAELGFEQVHKAYSGYEALELLQRHPIDIVVTDINMPE 60 M +++LVDDEP +++ L + W +LG+E V A +G EALE+ + D+++TDI MPE Sbjct: 1 MIRVMLVDDEPLILEGLKHLIDWGQLGYEIVATARNGVEALEIAKYVSFDLLITDIKMPE 60 Query: 61 ISGIELIAAIRSRWKHIRVVMLTGYAEFEYARKAIEEQASAYLLKPIANDQLIAVIVKLR 120 +G+ELIAA+ R K IR ++L+G+ EF + ++ + YLLKPI +LI+ + ++ Sbjct: 61 KTGLELIAALNEREKTIRSIVLSGFQEFHFVKQGLTLGIENYLLKPINEKELISTLSHVK 120 Query: 121 EEL 123 E++ Sbjct: 121 EKI 123 Score = 67.0 bits (162), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 29/99 (29%), Positives = 63/99 (63%), Gaps = 3/99 (3%) Query: 433 VLIRSIHEYINSNLHYVSLQAIADHVQMHPVYLSKMYKLETGKRISDYISQAKMEKAAYL 492 +++ IH++ + +L SL+ + ++P+YL ++++ E G + Y++Q ++++A L Sbjct: 407 TVLQHIHQHFSQDL---SLKTLGHSFHINPIYLGQLFQREVGCSFTKYLNQLRIDRAKKL 463 Query: 493 LIHTPLKIYEVSAELGYSNAHYFIKLFKEYSGMTPHEFR 531 L+++ + ++ ++GY +A YF K FK+Y MTP E+R Sbjct: 464 LLNSYDRAGQIGKKVGYGDATYFYKQFKKYEAMTPTEWR 502 >BH1910 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 506 Score = 90.9 bits (224), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 43/119 (36%), Positives = 72/119 (60%) Query: 1 MHQILLVDDEPYVVDDLSISLPWAELGFEQVHKAYSGYEALELLQRHPIDIVVTDINMPE 60 M+ +++VDDE V + L + W E GF + A +G E ++ D+++ DI MPE Sbjct: 1 MYDVMIVDDEAMVREGLKALISWEEYGFRVIDTARNGKEGFTKYRQLSPDLMIVDIRMPE 60 Query: 61 ISGIELIAAIRSRWKHIRVVMLTGYAEFEYARKAIEEQASAYLLKPIANDQLIAVIVKL 119 + G+ LI +IR+ I ++L+G+++F YA+KA+ Q YLLKP+ D+LI + K+ Sbjct: 61 VDGLSLIESIRAEDSAIHFIILSGHSDFNYAKKALGCQCDDYLLKPLDEDELIDSLKKV 119 Score = 61.2 bits (147), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 34/100 (34%), Positives = 56/100 (56%), Gaps = 4/100 (4%) Query: 434 LIRSIHEYINSNLHYVSLQAIADHVQMHPVYLSKMYKLETGKRISDYISQAKMEKAAYLL 493 +I IH+ NL L+ +A + YL K++K TG+ + Y+ + ++E LL Sbjct: 402 MIALIHKDYAKNLR---LETLASVFNYNRAYLGKLFKNYTGEYFNTYLDKVRIENGKRLL 458 Query: 494 IHTPLKIYEVSAELGYSNAHYFIKLFKEYSGMTPHEFRDR 533 K+YEV+ ++GY+N YF + FK+Y G++P FR R Sbjct: 459 -QKGYKVYEVAEKIGYANVDYFHRKFKKYVGVSPSTFRKR 497 >BH2109 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 525 Score = 88.2 bits (217), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 46/138 (33%), Positives = 80/138 (57%), Gaps = 1/138 (0%) Query: 1 MHQILLVDDEPYVVDDLSISLPWAELGFEQVHKAYSGYEALELLQRHPIDIVVTDINMPE 60 M+++LL DDE +V L + W + G+E +A +G +A +L+Q D+V+TDI MP Sbjct: 1 MYKVLLADDEFFVRHGLKSLIEWEKCGYEVAAEADNGEDAFKLVQEIKPDLVITDIRMPV 60 Query: 61 ISGIELIAAIRSRWK-HIRVVMLTGYAEFEYARKAIEEQASAYLLKPIANDQLIAVIVKL 119 G++LI + + + ++++GY +F YA+KA+ A ++LKPI D+L A ++KL Sbjct: 61 FDGLQLIQKVNETLSFNTKFIIISGYNDFSYAQKAVRFGAVDFVLKPIDQDELEAALIKL 120 Query: 120 REELRSEWEAWSSYQRTM 137 L E S ++ + Sbjct: 121 AATLDQEKATNSDQEKVL 138 Score = 73.2 bits (178), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 39/134 (29%), Positives = 77/134 (57%), Gaps = 5/134 (3%) Query: 403 QTPDMLRDWALEVIVLLREHFESERRDSRTVLIRSIHEYINSNLH-YVSLQAIADHVQMH 461 Q + + LE V+++E R+++ I + YI ++ H +SL++IA M+ Sbjct: 395 QLKQVFTKFVLEAAVIIQEL----RKENMKSDIYKVKTYIENHYHENISLKSIASLFYMN 450 Query: 462 PVYLSKMYKLETGKRISDYISQAKMEKAAYLLIHTPLKIYEVSAELGYSNAHYFIKLFKE 521 PVY+ +++K G +Y+ + +M +A LL T +++YEV+ +G+ + YF+ F++ Sbjct: 451 PVYMGQLFKKTFGVYFKEYLLKLRMNEAKKLLRQTDMRVYEVAERVGFGSTDYFVTQFEK 510 Query: 522 YSGMTPHEFRDRSL 535 + MTP E+R++ L Sbjct: 511 INKMTPTEYRNKLL 524 >SPy1556 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 246 Score = 86.7 bits (213), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 45/123 (36%), Positives = 77/123 (62%) Query: 1 MHQILLVDDEPYVVDDLSISLPWAELGFEQVHKAYSGYEALELLQRHPIDIVVTDINMPE 60 M+ +L+V+DE V + + +++ ++V++A +G A +L Q+ P DIV+TDINMP+ Sbjct: 1 MYSLLIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLFQKEPYDIVLTDINMPK 60 Query: 61 ISGIELIAAIRSRWKHIRVVMLTGYAEFEYARKAIEEQASAYLLKPIANDQLIAVIVKLR 120 ++GI+L I+ +V LTGY +F YA A++ A YLLKP + + ++ KLR Sbjct: 61 LNGIQLAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKADVEDMLGKLR 120 Query: 121 EEL 123 ++L Sbjct: 121 KKL 123 Score = 57.4 bits (137), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 34/101 (33%), Positives = 65/101 (64%), Gaps = 4/101 (3%) Query: 432 TVLIRSIHEYI-NSNLHYVSLQAIADHVQMHPVYLSKMYKLETGKRISDYISQAKMEKAA 490 + + +IHE + +S+L +L+++A + P YLS + K E G DY+ Q +++KA Sbjct: 144 SAIAMAIHERLADSDL---TLKSLAQQLGFSPNYLSVLIKKELGMPFQDYLVQERLKKAK 200 Query: 491 YLLIHTPLKIYEVSAELGYSNAHYFIKLFKEYSGMTPHEFR 531 LL+ + LKIYE++ ++G+ + +YF + FK+ G+TP +++ Sbjct: 201 LLLLTSNLKIYEIAEQVGFEDMNYFSQRFKQLVGVTPSQYK 241 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.137 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 39,087,267 Number of extensions: 1565779 Number of successful extensions: 5460 Number of sequences better than 1.0e-05: 281 Number of HSP's gapped: 5544 Number of HSP's successfully gapped: 292 Length of query: 535 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 424 Effective length of database: 25,576,357 Effective search space: 10844375368 Effective search space used: 10844375368 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 118 (50.1 bits)