BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0284.0002.p (539 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH1123 [T] COG4753 Response regulator containing CheY-like recei... 365 e-100 BH2109 [T] COG4753 Response regulator containing CheY-like recei... 144 4e-34 BH3842 [T] COG4753 Response regulator containing CheY-like recei... 115 1e-25 BS_yesS [K] COG2207 AraC-type DNA-binding domain-containing prot... 106 1e-22 BH2728 [T] COG4753 Response regulator containing CheY-like recei... 98 3e-20 >BH1123 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 526 Score = 365 bits (936), Expect = e-100, Method: Compositional matrix adjust. Identities = 197/545 (36%), Positives = 323/545 (59%), Gaps = 28/545 (5%) Query: 1 MWKIAIIDDERQVLKGMKGAIPWDELGAEWVGEAMNGEDGLEVIRRTQPDIVITDLYMPV 60 MWK+ IIDDE V++G+K I W LG E VGEA NG GL+++R T P IV+TD+YMP+ Sbjct: 1 MWKVVIIDDEEHVVRGLKKIISWKALGCECVGEAANGRRGLDIVRETSPHIVLTDIYMPI 60 Query: 61 MSGLDMMEQLRKEGFQGKIIILSGYSDFEHARAALRFHVTDYVSKPISLPTLKSILSNVV 120 M GLDM++ LR++GF G+++ILSGYS+FEHAR A++ ++TDY+SKP S+ T++++L V+ Sbjct: 61 MYGLDMIQILREDGFDGEVVILSGYSEFEHARKAMQLNITDYLSKPASVDTIETVLKRVI 120 Query: 121 XXXXXXXXXXXXXXXXXFKITLYEPFVEKEWVRSAAVGTLDHAYKDSTRLPPSYLY---- 176 K+ YEP VE EW++S G L + +P +L Sbjct: 121 NKLEEKQRQQGYLQELTNKVKRYEPLVETEWMKSLLTGRLRNG-----EIPEEFLAKITK 175 Query: 177 WQERKHVTVGIELIRDERARCLSVSDWNLFRFAVSNIACEVARKLFPEMEYTELHSTRAL 236 W++++H+ + + + L +DW LFR++V + EV + Y E+ + R+ Sbjct: 176 WKDQQHIACSLTY-DGPQNKELKPADWYLFRYSVHKMIREVLNGYPIDFRYLEMDAYRSA 234 Query: 237 LIIHPGSGHPEQ-LEGKLEELGIRLNESIGGYLKLVTRIGIGGVKDTWTKLSDSTEEAFR 295 L +H E L L E+ ++ + I + T + G VK+ WT LS+S EA Sbjct: 235 LCLHVNKSVSEPVLSCMLMEIKDQVEQGIYSSFNVKTTVHYGRVKEDWTDLSESFHEA-- 292 Query: 296 AMDQRALRVASAHEVYMYRENSSSEPGNVALFPVKFSYKLATAMKASQEAEAHQLVLDYI 355 M+ ++ + + + E G A FP++ S KL A++ + A +++ + + Sbjct: 293 CMESQSFPLGNPY-----------EDGTRATFPMESSQKLYDAIRYADATRAKEVLEEAV 341 Query: 356 TEMNK-QEGLSQGYVQMLGSELWGIITYSLYESGLVLDDLFTND-QIAKEISSLIVPDQL 413 + + GY +G E+W IITYSLY+ G+++ ++F D +A+ ++ + Sbjct: 342 GVLGEVPYSTLVGY--KVGIEIWTIITYSLYDIGILIQEMFDEDFDLAQHLTKQGNWQEW 399 Query: 414 ARWLMDKITRICSSRQWKGSSKHRQVVDFMTSYIHEHYAEELTLAELSDKVFISRNHLSI 473 R+L ++I IC +QW + KH+Q+++ + YI +H AE +TL +++D+++ISRN+L Sbjct: 400 IRFLCEQIEHICYHQQWDENIKHKQLIEQVMIYIEKHLAENITLQDIADELYISRNYLGQ 459 Query: 474 IFKNITGETFNNYLTRVRIEKARELLMERNMLVYEVAERVGYKNIPYFSTLFKKITGMNP 533 IFK + GE+F NY+TR+R+EKA++++ E N L+YEV+E+VGY N YF+T+FKK TG P Sbjct: 460 IFKKVVGESFKNYVTRLRMEKAKKMIQEGNFLIYEVSEKVGYVNPAYFTTMFKKYTGYTP 519 Query: 534 TELIK 538 +LI+ Sbjct: 520 RDLIQ 524 >BH2109 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 525 Score = 144 bits (363), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 142/577 (24%), Positives = 259/577 (44%), Gaps = 101/577 (17%) Query: 1 MWKIAIIDDERQVLKGMKGAIPWDELGAEWVGEAMNGEDGLEVIRRTQPDIVITDLYMPV 60 M+K+ + DDE V G+K I W++ G E EA NGED ++++ +PD+VITD+ MPV Sbjct: 1 MYKVLLADDEFFVRHGLKSLIEWEKCGYEVAAEADNGEDAFKLVQEIKPDLVITDIRMPV 60 Query: 61 MSGLDMMEQLRKE-GFQGKIIILSGYSDFEHARAALRFHVTDYVSKPISLPTLKSILSNV 119 GL +++++ + F K II+SGY+DF +A+ A+RF D+V KPI L++ L + Sbjct: 61 FDGLQLIQKVNETLSFNTKFIIISGYNDFSYAQKAVRFGAVDFVLKPIDQDELEAALIKL 120 Query: 120 VXXXXXXXXXXXXXXXXXFKITLYEPFV--------EKEWVRSAAVGTLD--HAYK---- 165 K+ L + F+ E E R AA ++ H Y Sbjct: 121 AATLDQEKATNSDQE----KVLLDQIFIHSLGENKKENEVRRWAAKLNINNRHFYYYLLL 176 Query: 166 --DSTRLPPSYLYWQERKHVTVGIELIRDERARCLSVSDWNLFRFAVSNIACEVARKLFP 223 ++ L ++ Q ++ + ++IR+ AR + ++ Sbjct: 177 EVNNLSLDKGFINEQYKEPIR---KVIRETVARQAATEEYTAI----------------- 216 Query: 224 EMEYTELHSTRALLIIHPGSGHPEQLEGKLEELGIRLNESIGGYLKLVTRIGIGGVKDTW 283 Y +L LLI S H ++ G++E L +L + I + + + +G D Sbjct: 217 ---YEQLDHAYGLLI---TSEHLKKFNGQIEPLAEKLRKDIQDFTNIPLTVYVGAKTDDL 270 Query: 284 TKLSDSTEEAFRAMDQRALR----VASAHEVYMYRENSSSEPGNVALFPVKFSYKLATAM 339 + + S E A +LR + + V+++ + S + L ++ T M Sbjct: 271 STIKKSYETA------NSLRNYKYIFNEKNVFIHEQTESVDTTYDEL----NNHLFVTLM 320 Query: 340 KASQEAEAHQLV--LDYI---------------TEMNKQEGLSQGYVQMLGSELWGIIT- 381 + +E + ++V +D I T +N+ VQ + + II+ Sbjct: 321 EQMEENNSDRIVNIIDKIFSEFQTKKFVPSAVKTSVNRCVHKVMQTVQAMEGDTGKIISA 380 Query: 382 --YSLYES-GLVLDDLFTNDQIAKEISSLIVPDQLARWLMDKITRICSSRQWKGSSKHRQ 438 + +ES L D L K++ +++++ I R+ S + Sbjct: 381 QAMTNWESYNLTFDQL-------KQV--------FTKFVLEAAVIIQELRKENMKSDIYK 425 Query: 439 VVDFMTSYIHEHYAEELTLAELSDKVFISRNHLSIIFKNITGETFNNYLTRVRIEKAREL 498 V ++ ++ HE+ ++L ++ +++ ++ +FK G F YL ++R+ +A++L Sbjct: 426 VKTYIENHYHEN----ISLKSIASLFYMNPVYMGQLFKKTFGVYFKEYLLKLRMNEAKKL 481 Query: 499 LMERNMLVYEVAERVGYKNIPYFSTLFKKITGMNPTE 535 L + +M VYEVAERVG+ + YF T F+KI M PTE Sbjct: 482 LRQTDMRVYEVAERVGFGSTDYFVTQFEKINKMTPTE 518 >BH3842 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 530 Score = 115 bits (289), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 121/542 (22%), Positives = 244/542 (45%), Gaps = 29/542 (5%) Query: 1 MWKIAIIDDERQVLKGMKGAIPWDELGAEWVGEAMNGEDGLEVIRRTQPDIVITDLYMPV 60 M + I+DDE+ +G+K + D VGEA NG +E TQPD+++ D+ MP Sbjct: 1 MINVLIVDDEQIEREGLKLFLK-DRPNIHIVGEASNGRQAIEKALETQPDLMMMDIKMPG 59 Query: 61 MSGLDMMEQLRKEGFQGKIIILSGYSDFEHARAALRFHVTDYVSKPISLPTLKSILSNVV 120 + G+ +++++++ + + I++S + FE+AR +R+ V +Y+ KP + + + L +V Sbjct: 60 VDGVQAVKEIKQQLPETEFIMVSAFDTFEYAREVMRYGVKEYLLKPTTKEDVLTALDRIV 119 Query: 121 XXXXXXXXXXXXXXXXXFKITLYEPFVEKEWVRSAAVGTLDHAYKDSTRLPPSYLYWQER 180 ++ FV+ E S +DH +L ++ Sbjct: 120 GEIEQAREEKNDQYKLQQRLEQISSFVQTE---SILYLLMDHIQDYEWMEWNEWLRTEQE 176 Query: 181 KHVTVGIELIRDERARCLSVSDWNLFRFAVSNIACEVARKLFPEMEYTEL--HSTRALLI 238 + V + + R W+ + I E+ +L P+ H L++ Sbjct: 177 GYAVVFSFHQQGKEIRKTEKQQWH------ARIKKEIGLQL-PKSTVGPFIGHHLPILML 229 Query: 239 IHPGSGHPEQLEGKLEELGIRLNESIGGYLKLV-TRIGIGGVKDTWTKLSDSTEEAFRAM 297 +G +Q + E++ I+L + ++ + G+GG+ S S EA A+ Sbjct: 230 TENENGMTKQ---EREQVVIQLLHKVKQAVQPAKVKTGVGGIYRLHF-FSTSYREALLAL 285 Query: 298 DQRALRVASAHEVYMYRENSSSEPGNVALFPVKFSYKLATAMKASQEAEAHQLVLDYITE 357 D + Y Y +N P++ KL A+K+ +A Q Y+ Sbjct: 286 D--IIYDHKQASYYFYDKNVKIRADEQ--LPIERENKLIEAIKSGDGEKALQAFDHYVQA 341 Query: 358 MNKQEGLSQGYVQMLGSELWGIITYSLYESGLVLDDLFTNDQIAKEISSLIVPDQLARWL 417 + + ++ +L+ I+ G +L+++ + + A++ + Q+ Sbjct: 342 ILRCSKHPLHDMRKYLQQLFIIL-------GRLLNEMGLHWETAQDFARFSTVHQVTEHG 394 Query: 418 MDKITRICSSRQWKGSSKHRQVVDFMTSYIHEHYAEELTLAELSDKVFISRNHLSIIFKN 477 +I I + Q ++ + ++ Y+H+H+ E LTL +L+ + +S ++S +FK Sbjct: 395 KSEILHIVRTLQEWRTTDEQSLMLLARDYVHDHFREPLTLDDLAKHIGLSPYYVSKLFKE 454 Query: 478 ITGETFNNYLTRVRIEKARELLMERNMLVYEVAERVGYKNIPYFSTLFKKITGMNPTELI 537 TF+ Y+T++R+E A++LL + E+ +GYK+ YFS +FKK+TG +P++ Sbjct: 455 RFDLTFSEYVTQLRVEHAKQLLSLTQKSLKEITYEIGYKDPNYFSRVFKKLTGKSPSDYR 514 Query: 538 KN 539 K+ Sbjct: 515 KS 516 >BS_yesS [K] COG2207 AraC-type DNA-binding domain-containing proteins Length = 761 Score = 106 bits (264), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 62/208 (29%), Positives = 120/208 (57%), Gaps = 3/208 (1%) Query: 327 FPVKFSYKLATAMKASQEAEAHQLVLDYITEMNKQEGLSQGYVQMLGSELWGIITYSLYE 386 +P + ++ ++ ++ EA +L+ + E++++ + + +V +L+ I + Sbjct: 545 YPFELEKQIVQTIRLERKQEAKELIDGCMKELSEKAAIDR-HVHSALIQLFSRIQEDILH 603 Query: 387 SGLVLDDLFTNDQIAKEISSLIVPDQLARWLMDKI-TRICSSRQWKGSSKHRQVVDFMTS 445 SGL +LF + +IS L P++ A WLMD + T S + + + + +Q+ + + + Sbjct: 604 SGLNPSELFQHRNPFLDISELREPNEAAAWLMDVVVTPYLSKLEGRKNRQQKQLAERVIA 663 Query: 446 YIHEHYAEELTLAELSDKVFISRNHLSIIFKNITGETFNNYLTRVRIEKARELLMERNML 505 IHE Y +++L +D + ++ LS FK +TG F +Y+T++RIEKA+ELL+ N Sbjct: 664 MIHEQYMADISLESCADALGMNSYTLSKAFKQVTGINFIDYVTQIRIEKAKELLVNTNKK 723 Query: 506 VYEVAERVGYKNIPYFSTLFKKITGMNP 533 +++V+E VGY++ YF+ +FKK GM P Sbjct: 724 IHDVSEEVGYRH-NYFNRIFKKQVGMPP 750 >BH2728 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 510 Score = 98.2 bits (243), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 41/106 (38%), Positives = 73/106 (68%) Query: 1 MWKIAIIDDERQVLKGMKGAIPWDELGAEWVGEAMNGEDGLEVIRRTQPDIVITDLYMPV 60 M + I+DDE+ + +G+ W++ G + VGEA NG+D LE+I + +P IV+TD+ MPV Sbjct: 1 MCNVLIVDDEKLIRQGIINFFDWEKEGFQIVGEAANGKDALELISKNEPHIVMTDIVMPV 60 Query: 61 MSGLDMMEQLRKEGFQGKIIILSGYSDFEHARAALRFHVTDYVSKP 106 M G+D++++++++ + +II+LS + +FE+ R+ V DY+ KP Sbjct: 61 MDGIDLVKRVKRDFPEVEIIVLSSFEEFEYVRSTFHSGVADYILKP 106 Score = 72.8 bits (177), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 36/92 (39%), Positives = 57/92 (61%) Query: 443 MTSYIHEHYAEELTLAELSDKVFISRNHLSIIFKNITGETFNNYLTRVRIEKARELLMER 502 M +YI EH++E L+L++L++ + ++LS F+ E F+ YL +VRI KA+E L Sbjct: 405 MLAYIEEHHSEPLSLSQLANYFHFNPSYLSAYFRQHHDEGFSEYLNKVRIRKAKEWLKSS 464 Query: 503 NMLVYEVAERVGYKNIPYFSTLFKKITGMNPT 534 + + E+ VGY + YF +FKK TGM P+ Sbjct: 465 TIPISEIYALVGYSDHSYFCKVFKKRTGMPPS 496 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.135 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 37,704,341 Number of extensions: 1499861 Number of successful extensions: 7354 Number of sequences better than 1.0e-05: 225 Number of HSP's gapped: 7446 Number of HSP's successfully gapped: 236 Length of query: 539 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 428 Effective length of database: 25,576,357 Effective search space: 10946680796 Effective search space used: 10946680796 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 118 (50.1 bits)