BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0273.0010.p (247 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0321 [TK] COG0745 Response regulators consisting of a CheY-li... 216 3e-56 BH0820 [TK] COG0745 Response regulators consisting of a CheY-lik... 200 2e-51 SA0017 [TK] COG0745 Response regulators consisting of a CheY-lik... 195 5e-50 BS_yclJ [TK] COG0745 Response regulators consisting of a CheY-li... 193 2e-49 lin0315 [TK] COG0745 Response regulators consisting of a CheY-li... 193 2e-49 >CAC0321 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 230 Score = 216 bits (550), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 104/211 (49%), Positives = 146/211 (69%), Gaps = 2/211 (0%) Query: 36 KDYIRLQGYDVHIADNGIDGLRLVETLFPDFIILDIMLPDANGIELCRQIRDKTRIPILI 95 KDY+ L + V I +G GL + + IILD+MLP+ +G E+C+QIR PIL+ Sbjct: 18 KDYLELSNFKVDIEVSGKTGLEAAKEKNYELIILDLMLPEIDGFEICKQIRKIKNTPILM 77 Query: 96 LSARGSDTDKVLGLGFGADDYMTKPFSLSELVARIQAHLRRMEGMGNIPGHG--DLISLG 153 +SA+ D DK+ GLG GADDYMTKPFS SELVAR++AH+ R E + N D I + Sbjct: 78 VSAKKEDIDKIRGLGLGADDYMTKPFSPSELVARVKAHISRYERLVNSSNKNLDDEIEIR 137 Query: 154 ALTIDKKAYKTTLNGQELALSAKEFELLYFLAEHKNQVFSKSQLLDQIWGYTSHGDESTI 213 L I+K + K +NG+E +AKEF+LL FLA++ ++VFSK +L D+IWG S G+ +T+ Sbjct: 138 GLNINKASRKVFVNGKESQFTAKEFDLLVFLAQNPDRVFSKEELFDKIWGMDSFGEIATV 197 Query: 214 TVYIRRLREKLEADPSSPSYIKTVWGVGYKF 244 TV+I+++REK+E D S+P YI+TVWG GY+F Sbjct: 198 TVHIKKIREKIEKDTSNPEYIETVWGAGYRF 228 >BH0820 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 234 Score = 200 bits (509), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 94/215 (43%), Positives = 140/215 (65%), Gaps = 2/215 (0%) Query: 32 SRILKDYIRLQGYDVHIADNGIDGLRLVETLFPDFIILDIMLPDANGIELCRQIRDKTRI 91 S ++K++++L+GY V A +G + RL E D ++LD+MLP NGI+ + IR K+ + Sbjct: 16 SEMVKEHLQLEGYHVCCAFDGEEATRLFEQNTYDLVLLDLMLPRRNGIDCLQWIRTKSVV 75 Query: 92 PILILSARGSDTDKVLGLGFGADDYMTKPFSLSELVARIQAHLRRM--EGMGNIPGHGDL 149 P+LI+SA+ SD DK LGLGFGADDY+TKPFS+ EL AR++A +RR + + Sbjct: 76 PVLIMSAKDSDVDKALGLGFGADDYITKPFSMIELTARVKAAIRRTVNYAQASQSAENER 135 Query: 150 ISLGALTIDKKAYKTTLNGQELALSAKEFELLYFLAEHKNQVFSKSQLLDQIWGYTSHGD 209 I + L ++ ++ G+E+ L+AKEF++L H +VF+K QL +W + D Sbjct: 136 IKIHELVVELSSFTVKKKGEEIKLTAKEFQILKLFVTHPKKVFTKEQLYRSVWNDDYYSD 195 Query: 210 ESTITVYIRRLREKLEADPSSPSYIKTVWGVGYKF 244 E+ I V+IRRLREK+E PS P YIKT+WG+GY+ Sbjct: 196 ENVINVHIRRLREKIEDTPSKPQYIKTIWGIGYRM 230 >SA0017 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 235 Score = 195 bits (496), Expect = 5e-50, Method: Compositional matrix adjust. Identities = 97/214 (45%), Positives = 142/214 (66%), Gaps = 8/214 (3%) Query: 34 ILKDYIRLQGYDVHIADNGIDGLRLVETLFPDFIILDIMLPDANGIELCRQIRDKTRIPI 93 IL+ ++ +GYDV+ A +G D + L+ PD ++LDIMLP +G+E+CR++R K +PI Sbjct: 19 ILEFNLKKEGYDVYCAYDGNDAVDLIYEEEPDIVLLDIMLPGRDGMEVCREVRKKYEMPI 78 Query: 94 LILSARGSDTDKVLGLGFGADDYMTKPFSLSELVARIQAHLRR-----MEGMGNIPGHGD 148 ++L+A+ S+ DKVLGL GADDY+TKPFS EL+AR++A+LRR + GN+ Sbjct: 79 IMLTAKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLRRHYSQPAQDTGNVTNE-- 136 Query: 149 LISLGALTIDKKAYKTTLNGQELALSAKEFELLYFLAEHKNQVFSKSQLLDQIWGYTSHG 208 I++ + I AY G+++ L+ +EFEL ++L++H QV ++ LL +WGY G Sbjct: 137 -ITIKDIVIYPDAYSIKKRGEDIELTHREFELFHYLSKHMGQVMTREHLLQTVWGYDYFG 195 Query: 209 DESTITVYIRRLREKLEADPSSPSYIKTVWGVGY 242 D T+ V IRRLREK+E DPS P YI T GVGY Sbjct: 196 DVRTVDVTIRRLREKIEDDPSHPEYIVTRRGVGY 229 >BS_yclJ [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 227 Score = 193 bits (491), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 94/207 (45%), Positives = 142/207 (68%), Gaps = 3/207 (1%) Query: 42 QGYDVHIADNGIDGLRLVETLFPDFIILDIMLPDANGIELCRQIRDKTRIPILILSARGS 101 +G++ +G++G + D IILDIMLP +G+ +CR+IR+ + +PI++L+A+ + Sbjct: 23 EGFEAEFVHDGLEGYQRFTEENWDLIILDIMLPSMDGVTICRKIRETSTVPIIMLTAKDT 82 Query: 102 DTDKVLGLGFGADDYMTKPFSLSELVARIQAHLRRMEGMGNIPGHGDLISLGALTIDKKA 161 ++D+V+G GADDY+TKPFS LVARI+A +RR + G D+I TI+KK Sbjct: 83 ESDQVIGFEMGADDYVTKPFSPLTLVARIKAVIRRYKATGKAVIDEDMIETECFTINKKT 142 Query: 162 YKTTLNGQELA-LSAKEFELLYFLAEHKNQVFSKSQLLDQIWGYTSHGDESTITVYIRRL 220 + LNG+ + L+ KEF+LLY+L ++ QVFS+ QLL+Q+WGY +GDE T+ V+I+RL Sbjct: 143 REVLLNGEPVENLTPKEFDLLYYLVQNPRQVFSREQLLEQVWGYQFYGDERTVDVHIKRL 202 Query: 221 REKLEADPSSPSYIKTVWGVGYKFNLD 247 R+KL A P ++ TVWGVGYKF+ D Sbjct: 203 RKKL-ASEDKP-FLYTVWGVGYKFDED 227 >lin0315 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 237 Score = 193 bits (490), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 95/212 (44%), Positives = 143/212 (67%), Gaps = 3/212 (1%) Query: 34 ILKDYIRLQGYDVHIADNGIDGLRLVETLFPDFIILDIMLPDANGIELCRQIRDKTRIPI 93 I+K + +G+DV+ A +G + L LVE + PD I+LDIMLP +GIE+CR++R K +PI Sbjct: 18 IVKFNLNKEGFDVYCAYDGDEALELVEEVQPDLILLDIMLPGRDGIEVCREVRKKYDMPI 77 Query: 94 LILSARGSDTDKVLGLGFGADDYMTKPFSLSELVARIQAHLRR---MEGMGNIPGHGDLI 150 ++++A+ S+ DKV+GL GADDY+TKPFS EL+AR++A+LRR + + Sbjct: 78 IMVTAKDSEIDKVIGLELGADDYVTKPFSNRELIARVKANLRRHSQVSSNAAEEEENSEL 137 Query: 151 SLGALTIDKKAYKTTLNGQELALSAKEFELLYFLAEHKNQVFSKSQLLDQIWGYTSHGDE 210 +G+L I AY + G+ + L+ +EFELL++LA+H QV ++ LL +WGY GD Sbjct: 138 EIGSLIIHPDAYVASKRGETIELTHREFELLHYLAKHMGQVMTREHLLQTVWGYDYFGDV 197 Query: 211 STITVYIRRLREKLEADPSSPSYIKTVWGVGY 242 T+ V +RRLREK+E +PS P+++ T GVGY Sbjct: 198 RTVDVTVRRLREKIEDNPSHPAWLVTRRGVGY 229 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.139 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 17,619,700 Number of extensions: 653729 Number of successful extensions: 2335 Number of sequences better than 1.0e-05: 376 Number of HSP's gapped: 2028 Number of HSP's successfully gapped: 377 Length of query: 247 Length of database: 38,378,431 Length adjustment: 104 Effective length of query: 143 Effective length of database: 26,383,695 Effective search space: 3772868385 Effective search space used: 3772868385 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 114 (48.5 bits)