BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0272.0007.p (535 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH3842 [T] COG4753 Response regulator containing CheY-like recei... 120 5e-27 BH0793 [T] COG4753 Response regulator containing CheY-like recei... 119 9e-27 BH2109 [T] COG4753 Response regulator containing CheY-like recei... 92 2e-18 BH3679 [T] COG4753 Response regulator containing CheY-like recei... 91 4e-18 SPy1587 [T] COG4753 Response regulator containing CheY-like rece... 84 5e-16 >BH3842 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 530 Score = 120 bits (301), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 125/549 (22%), Positives = 237/549 (43%), Gaps = 52/549 (9%) Query: 1 MYNVLVADDEPRHRRGIADMIKQLRPEYRIF-MVKDGLEALRIIEDNRIDIILTDIRMPN 59 M NVL+ DDE R G+ +K RP I +G +A+ + + D+++ DI+MP Sbjct: 1 MINVLIVDDEQIEREGLKLFLKD-RPNIHIVGEASNGRQAIEKALETQPDLMMMDIKMPG 59 Query: 60 MDGLTLIERMESRRERVKIVILSVYGNFEYARQALQLGAFDYLLKPLAFPELSGILDKLD 119 +DG+ ++ ++ + + +++S + FEYAR+ ++ G +YLLKP ++ LD++ Sbjct: 60 VDGVQAVKEIKQQLPETEFIMVSAFDTFEYAREVMRYGVKEYLLKPTTKEDVLTALDRIV 119 Query: 120 TALEKERLSLQDGAVLRQRLSSAAPVYEQHLLSRWMRSASSEEELQEIRSLFPAVSGGFV 179 +E+ R D L+QRL + + + + + E E G+ Sbjct: 120 GEIEQAREEKNDQYKLQQRLEQISSFVQTESILYLLMDHIQDYEWMEWNEWLRTEQEGYA 179 Query: 180 MLAKF--QKREVAEFYTLEDFEELKTSVINWMKEIYQTVGPSLSFNLEGADPMIGS---I 234 ++ F Q +E+ KT W I + +G L + G P IG I Sbjct: 180 VVFSFHQQGKEIR-----------KTEKQQWHARIKKEIGLQLPKSTVG--PFIGHHLPI 226 Query: 235 VTSAHSLEWLLKRDMEQFR-QFIRQVRDEF--GLTLTLGAGNWVADLYSEAPQSFEQAQK 291 + + + K++ EQ Q + +V+ T G + +S S+ +A Sbjct: 227 LMLTENENGMTKQEREQVVIQLLHKVKQAVQPAKVKTGVGGIYRLHFFS---TSYREALL 283 Query: 292 ALEYTFYTGAGQLVLFD---EIAYNPDKPSLKMVPADTGITDALARLDRDTVAQALKTLI 348 AL+ + +D +I + P + + + +A+ D + QA + Sbjct: 284 ALDIIYDHKQASYYFYDKNVKIRADEQLP----IERENKLIEAIKSGDGEKALQAFDHYV 339 Query: 349 GRLLEGDCPSPAHLKDCVLYALVNEVKGSELFLRQEEVSNFISEMEFQIPACE------S 402 +L C S L D Y +LF+ + ++EM + + Sbjct: 340 QAILR--C-SKHPLHDMRKYL-------QQLFII---LGRLLNEMGLHWETAQDFARFST 386 Query: 403 LDEVEKRAAFYLNRIMDSIGERKENKSGRTISLCKAFLEAHYMEDLSLEYVARQXXXXXX 462 + +V + + I+ ++ E + + L + ++ H+ E L+L+ +A+ Sbjct: 387 VHQVTEHGKSEILHIVRTLQEWRTTDEQSLMLLARDYVHDHFREPLTLDDLAKHIGLSPY 446 Query: 463 XXXXXXKQHTSLTFTEYLLRLRMDKAKELLQNGDLKISAIALSVGFRDAGYFTRVFKRET 522 K+ LTF+EY+ +LR++ AK+LL + I +G++D YF+RVFK+ T Sbjct: 447 YVSKLFKERFDLTFSEYVTQLRVEHAKQLLSLTQKSLKEITYEIGYKDPNYFSRVFKKLT 506 Query: 523 GLSPEEFRK 531 G SP ++RK Sbjct: 507 GKSPSDYRK 515 >BH0793 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 508 Score = 119 bits (299), Expect = 9e-27, Method: Compositional matrix adjust. Identities = 137/557 (24%), Positives = 229/557 (41%), Gaps = 80/557 (14%) Query: 1 MYNVLVADDEPRHRRGIADMIKQLRPEYRIF-MVKDGLEALRIIEDNRIDIILTDIRMPN 59 M V++ DDEP G+ +I + Y I ++G+EAL I + D+++TDI+MP Sbjct: 1 MIRVMLVDDEPLILEGLKHLIDWGQLGYEIVATARNGVEALEIAKYVSFDLLITDIKMPE 60 Query: 60 MDGLTLIERMESRRERVKIVILSVYGNFEYARQALQLGAFDYLLKPLAFPE----LSGIL 115 GL LI + R + ++ ++LS + F + +Q L LG +YLLKP+ E LS + Sbjct: 61 KTGLELIAALNEREKTIRSIVLSGFQEFHFVKQGLTLGIENYLLKPINEKELISTLSHVK 120 Query: 116 DKLDTALEKERLSLQDGAVLRQRLSSAAPVYEQHLLSRWMRSASSEEELQEIRSLFPAVS 175 +K++ A KE +L VLR H + RW+ E ++ + +P V Sbjct: 121 EKINHAFLKEESTL----VLR-----------DHSIWRWLVGKMGHTEFKQRMAFYPEVQ 165 Query: 176 GGF-----VMLAKFQKREVAEFYTLEDFEELKTSVINWMKEIYQTVGPSLSFNLEGADPM 230 F ++ ++ + E Y L+ E +TS + V PS Sbjct: 166 WKFPLRIGLLKMEWDQHTEEELYRLQRTLEQETSAMT-------VVTPS----------- 207 Query: 231 IGSIVTSAHSLEWLLKRDMEQFRQFIRQVRDEFGLTLTLGAGNWVADLYSEAPQSFEQAQ 290 G ++ E + D Q R + V E + G ++SE + Sbjct: 208 -GDLLFIWCGFE--RESDWGQERSRFQSVVTEAPI------GQPFVFVHSEPISEIQCLY 258 Query: 291 KALEYTFYTGAGQLVLFDEIAYNPDKPSLK----MVPADTGIT---DALARLDRDTVAQA 343 + +L+L + + D+ + K ++P IT D L + Sbjct: 259 EVYREMEMKCELKLLLPERDHHMADQLTFKRESELIPPQMNITLEQDIFEHLANRHYQKV 318 Query: 344 LKTLIGRLLEGDCP-SPAHLKDCVLYALVNEVKGSELFLRQEEVSNFISEMEF------- 395 K L L E C +P LK ++ E F R + S FI ++ F Sbjct: 319 RKDLEHMLSESHCERNPIFLKSVLM----------EFFYRLK--SQFIVQLPFDQYVQIV 366 Query: 396 -QIPACESLDEVEKRAAFYLNRIMDSIGERKENKSGRTISLCKAFLEAHYMEDLSLEYVA 454 QI E+ E K ++ + D + E I + H+ +DLSL+ + Sbjct: 367 QQIVHVETTSEAMKMIDRCIDLLEDDHLQENEKNYSPIIQTVLQHIHQHFSQDLSLKTLG 426 Query: 455 RQXXXXXXXXXXXXKQHTSLTFTEYLLRLRMDKAKELLQNGDLKISAIALSVGFRDAGYF 514 ++ +FT+YL +LR+D+AK+LL N + I VG+ DA YF Sbjct: 427 HSFHINPIYLGQLFQREVGCSFTKYLNQLRIDRAKKLLLNSYDRAGQIGKKVGYGDATYF 486 Query: 515 TRVFKRETGLSPEEFRK 531 + FK+ ++P E+RK Sbjct: 487 YKQFKKYEAMTPTEWRK 503 >BH2109 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 525 Score = 92.0 bits (227), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 50/133 (37%), Positives = 84/133 (63%), Gaps = 2/133 (1%) Query: 1 MYNVLVADDEPRHRRGIADMIKQLRPEYRIFMVKD-GLEALRIIEDNRIDIILTDIRMPN 59 MY VL+ADDE R G+ +I+ + Y + D G +A +++++ + D+++TDIRMP Sbjct: 1 MYKVLLADDEFFVRHGLKSLIEWEKCGYEVAAEADNGEDAFKLVQEIKPDLVITDIRMPV 60 Query: 60 MDGLTLIERM-ESRRERVKIVILSVYGNFEYARQALQLGAFDYLLKPLAFPELSGILDKL 118 DGL LI+++ E+ K +I+S Y +F YA++A++ GA D++LKP+ EL L KL Sbjct: 61 FDGLQLIQKVNETLSFNTKFIIISGYNDFSYAQKAVRFGAVDFVLKPIDQDELEAALIKL 120 Query: 119 DTALEKERLSLQD 131 L++E+ + D Sbjct: 121 AATLDQEKATNSD 133 Score = 69.7 bits (169), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 38/109 (34%), Positives = 60/109 (55%), Gaps = 1/109 (0%) Query: 424 RKENKSGRTISLCKAFLEAHYMEDLSLEYVARQXXXXXXXXXXXXKQHTSLTFTEYLLRL 483 RKEN I K ++E HY E++SL+ +A K+ + F EYLL+L Sbjct: 415 RKENMKS-DIYKVKTYIENHYHENISLKSIASLFYMNPVYMGQLFKKTFGVYFKEYLLKL 473 Query: 484 RMDKAKELLQNGDLKISAIALSVGFRDAGYFTRVFKRETGLSPEEFRKK 532 RM++AK+LL+ D+++ +A VGF YF F++ ++P E+R K Sbjct: 474 RMNEAKKLLRQTDMRVYEVAERVGFGSTDYFVTQFEKINKMTPTEYRNK 522 >BH3679 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 257 Score = 90.9 bits (224), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 51/151 (33%), Positives = 78/151 (51%), Gaps = 21/151 (13%) Query: 3 NVLVADDEPRHRRGIADMIKQLRPEY-RIFMVKDGLEALRIIEDNRIDIILTDIRMPNMD 61 VL+ DDEPR RRG+ ++ P+ + EA+ + + ID+I+TDIRMP M Sbjct: 5 TVLIVDDEPRSRRGLKRTLEAWSPKLLNVQTAASAKEAITRLNEETIDLIITDIRMPEMS 64 Query: 62 GLTLIERMESRRERVKIVILSVYGNFEYARQALQLGAFDYLLKPLA-------------- 107 GL L++ ++ + + +++S Y FEYA AL+LG YLLKP+ Sbjct: 65 GLHLVKALQEQNPKPVCIVISAYSEFEYAHTALELGVRHYLLKPVKKEKLIEAVESALQM 124 Query: 108 ------FPELSGILDKLDTALEKERLSLQDG 132 F ++ + D+ A+EKERLS D Sbjct: 125 KKEQDRFGQVEKVWDEKIDAIEKERLSSSDS 155 Score = 69.7 bits (169), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 38/114 (33%), Positives = 64/114 (56%), Gaps = 1/114 (0%) Query: 418 MDSIGERKENKSGRTISLCKAFLEAHYMEDLSLEYVARQXXXXXXXXXXXXKQHTSLTFT 477 +D+I E++ S +I +++AH + + L+ VA+ K+ T++TF+ Sbjct: 142 IDAI-EKERLSSSDSIHEALHYIDAHLDQKIGLKDVAKSVHLNPSYLSALFKEKTNMTFS 200 Query: 478 EYLLRLRMDKAKELLQNGDLKISAIALSVGFRDAGYFTRVFKRETGLSPEEFRK 531 EYL R R+ AK LL + D IS IA G++ A YF ++FK G++P ++RK Sbjct: 201 EYLTRKRLQHAKHLLVSTDRPISDIAEKCGYQTAKYFIKIFKEHEGMTPTQYRK 254 >SPy1587 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 494 Score = 84.3 bits (207), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 56/183 (30%), Positives = 92/183 (50%), Gaps = 13/183 (7%) Query: 1 MYNVLVADDEPRHRRGIADMIKQLRPEYRIFMV-KDGLEALRIIEDNRIDIILTDIRMPN 59 MY VL+ DDE +G+ +I + + + G EAL + +D++++D+ MP Sbjct: 1 MYKVLLVDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALAYLTQYPVDVMISDVTMPG 60 Query: 60 MDGLTLIERMESRRERVKIVILSVYGNFEYARQALQLGAFDYLLKPLAFPELSGILDKLD 119 M GL LIE ++ +++ +ILS Y F Y ++A++L YLLKP+ EL + + Sbjct: 61 MTGLDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGYLLKPVDKAELQAKMKQF- 119 Query: 120 TALEKERLSLQDGAVLRQRLSSAAPVYEQHLLSRWMRSASSEEELQEIRSLFPAVS-GGF 178 K+ L Q +RQ Y LL+ W+ SE+E Q++ PA + GF Sbjct: 120 ----KDWLDAQQAESIRQE------AYHDSLLTLWLTDELSEKEFQQLSQGLPAAALTGF 169 Query: 179 VML 181 +L Sbjct: 170 TVL 172 Score = 59.3 bits (142), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 34/121 (28%), Positives = 61/121 (50%), Gaps = 2/121 (1%) Query: 414 LNRIMDSIGERK--ENKSGRTISLCKAFLEAHYMEDLSLEYVARQXXXXXXXXXXXXKQH 471 L +++D + E + +S + Y ++L+L+ +A + K Sbjct: 362 LKKVLDVTNQNNSPEKRYSDLVSETIDCIRKEYHQELTLKAIADRLHVNGVYLGQCFKNE 421 Query: 472 TSLTFTEYLLRLRMDKAKELLQNGDLKISAIALSVGFRDAGYFTRVFKRETGLSPEEFRK 531 T +FT+YL +R+ KA++LL + I+ IA G+ YF ++FK+ GLSP+EFR Sbjct: 422 TERSFTQYLNHVRIQKAQQLLLYTNQSINEIAYETGYNTNHYFIKMFKKLNGLSPKEFRD 481 Query: 532 K 532 + Sbjct: 482 R 482 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.137 0.385 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 36,483,853 Number of extensions: 1436568 Number of successful extensions: 4688 Number of sequences better than 1.0e-05: 348 Number of HSP's gapped: 4785 Number of HSP's successfully gapped: 359 Length of query: 535 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 424 Effective length of database: 25,576,357 Effective search space: 10844375368 Effective search space used: 10844375368 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 118 (50.1 bits)