BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0270.0006.p
         (135 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

PA1344 [IQR] COG1028 Dehydrogenases with different specificities...    69   3e-12
TVN1344 [IQR] COG1028 Dehydrogenases with different specificitie...    58   4e-09
PAB1085 [IQR] COG1028 Dehydrogenases with different specificitie...    57   6e-09
AGc1817 [IQR] COG1028 Dehydrogenases with different specificitie...    51   4e-07
L0185 [IQR] COG1028 Dehydrogenases with different specificities ...    50   1e-06

>PA1344 [IQR] COG1028 Dehydrogenases with different specificities (related
           to short-chain alcohol dehydrogenases)
          Length = 264

 Score = 68.6 bits (166), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 38/110 (34%), Positives = 56/110 (50%), Gaps = 3/110 (2%)

Query: 1   MDMGLNNKTALXXXXXXSTKGIGKAIAVELAKEGVNVLINGRSYEEAERTVNEMKSNFPA 60
           M + L++K A+      ST GIG AIA  LA  G  V++NGRS    +R +  +++  P 
Sbjct: 1   MQIDLSDKLAIVSG---STAGIGFAIASGLAAAGATVVVNGRSQAAVDRAIAAIRNGQPD 57

Query: 61  TSPQNAAADIVDTRQREALFEKYPDIDILVNNTGIYEIMQYEDVDDEIWE 110
              +  A D+       A     P  DILVNN GI+E+  + D++D  W 
Sbjct: 58  ARVRGVAGDLGTAEGCAAFVAAEPKADILVNNLGIFELKDFFDIEDAEWS 107


>TVN1344 [IQR] COG1028 Dehydrogenases with different specificities (related
           to short-chain alcohol dehydrogenases)
          Length = 255

 Score = 58.2 bits (139), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 43/111 (38%), Positives = 60/111 (54%), Gaps = 13/111 (11%)

Query: 1   MDMGLNNKTALXXXXXXSTKGIGKAIAVELAKEGVNVLINGRSYEEAERTVNEMKSNFPA 60
           M   L  KTAL      ++KG+G+AIA E AKEG  V IN   Y   E++  E+K     
Sbjct: 1   MSGKLEGKTALITG---ASKGLGRAIAEEFAKEGARVAIN---YAHDEKSALEVK---KI 51

Query: 61  TSPQNAAADIVDTRQ----REALFEKYPDIDILVNNTGIYEIMQYEDVDDE 107
           T  +   AD+ +  Q       + EK   IDILVNN+GI+ +M +E+ D+E
Sbjct: 52  TGGEIFKADVSNRDQVKEMARQIHEKLGKIDILVNNSGIWYLMPFENYDEE 102


>PAB1085 [IQR] COG1028 Dehydrogenases with different specificities (related
           to short-chain alcohol dehydrogenases)
          Length = 240

 Score = 57.4 bits (137), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 44/116 (37%), Positives = 60/116 (51%), Gaps = 15/116 (12%)

Query: 3   MGLNNKTALXXXXXXSTKGIGKAIAVELAKEGVNVLINGRSYEEAERTVNEMKSNFPATS 62
           M L  K AL      +++GIG+AIA+ELAK GVNV+IN RS EE  +   E+   +   +
Sbjct: 1   MELKGKVALITG---ASRGIGRAIAIELAKRGVNVVINYRSNEEEAKKTEELCRQYGVET 57

Query: 63  PQNAAADIVDTRQREALFE-------KYPDIDILVNNTGIY-EIMQYEDVDDEIWE 110
               A    D   RE + E       K+  IDIL+NN GI  +     +V DE W+
Sbjct: 58  LLVKA----DVSNREEVREMVKKVIDKFGRIDILINNAGILGKTKDPLEVTDEEWD 109


>AGc1817 [IQR] COG1028 Dehydrogenases with different specificities (related
           to short-chain alcohol dehydrogenases)
          Length = 121

 Score = 51.2 bits (121), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 0/97 (0%), Positives = 0/97 (0%), Gaps = 6/97 (6%)

Query: 1   MDMGLNNKTALXXXXXXSTKGIGKAIAVELAKEGVNVLINGRSYE---EAERTVNEMKSN 57
               L +                 A    +  +    L              TV      
Sbjct: 32  YLSALEHGKRGKPS---FDLLQRIAGYFNIIWDEAEELFFLAGSSDPKVVIDTVGLPPQY 88

Query: 58  FPATSPQNAAADIVDTRQREALFEKYPDIDILVNNTG 94
                                                
Sbjct: 89                                        125


>L0185 [IQR] COG1028 Dehydrogenases with different specificities
          (related to short-chain alcohol dehydrogenases)
          Length = 243

 Score = 49.7 bits (117), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 32/79 (40%), Positives = 40/79 (50%), Gaps = 1/79 (1%)

Query: 18 STKGIGKAIAVELAKEGVNVLINGRSYEEAERTVNEMKSNFPATSPQNAAADIVDTRQRE 77
          ST+GIGKAIA++ AK G N++INGRS    E           A       +   D +Q  
Sbjct: 13 STRGIGKAIALQFAKAGSNLIINGRSAISEELLAEFTAYGVKAVGISGDISKSEDAKQMV 72

Query: 78 A-LFEKYPDIDILVNNTGI 95
          A   E    +DILVNN GI
Sbjct: 73 AEAIETLGSVDILVNNAGI 91


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.316    0.134    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 9,016,847
Number of extensions: 327369
Number of successful extensions: 1039
Number of sequences better than 1.0e-05: 17
Number of HSP's gapped: 1148
Number of HSP's successfully gapped: 17
Length of query: 135
Length of database: 38,378,431
Length adjustment: 95
Effective length of query: 40
Effective length of database: 27,421,701
Effective search space: 1096868040
Effective search space used: 1096868040
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 110 (47.0 bits)