BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0269.0011.p (387 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SP0662 [T] COG2972 Predicted signal transduction protein with a ... 207 3e-53 BS_yesM [T] COG2972 Predicted signal transduction protein with a... 176 5e-44 BH2110 [T] COG2972 Predicted signal transduction protein with a ... 167 2e-41 BH1909 [T] COG2972 Predicted signal transduction protein with a ... 155 1e-37 BH1122 [T] COG2972 Predicted signal transduction protein with a ... 148 1e-35 >SP0662 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 563 Score = 207 bits (526), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 119/387 (30%), Positives = 207/387 (53%), Gaps = 30/387 (7%) Query: 3 IGTTGFFYLLDEQNNPLYVPPVQAGELALVQDNLIPAGEKGRSGSFVLQTGGPPRFIVHT 62 +G GF ++++E + +Y P + + + P + G+ T G ++ Sbjct: 197 LGQQGFAFIINENHEFVYHPQHTVYSSSSKMEAMKPYIDTGQG-----YTPGHKSYVSQE 251 Query: 63 SSLATGWTIIGIAPLQEIVAEANRIRQLIIISVGLSIIFAIXXXXXXXXXXXXPIQLLQH 122 T WT++G++ L+++ +++ ++ + S++ + P++ L+ Sbjct: 252 KIAGTDWTVLGVSSLEKLDQVRSQLLWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRE 311 Query: 123 KMRLTASGYLEAKVKPDGTDEIADLGQSFNIMVEQIKELLAQSIRKQQQLQKA-ELRTLQ 181 M ASG + K G E+ ++ + FN M++QI +L+ +IR Q++ + +L+ L Sbjct: 312 TMLEIASGAQNLRAKEVGAYELREVTRQFNAMLDQIDQLMV-AIRSQEETTRQYQLQALS 370 Query: 182 AQINPHFLYNTLDSIVWMAEAGNHDGVIRLVKALSAFFRLSLNNGRDWIQIRSELAHVQS 241 +QINPHFLYNTLD+I+WMAE + V+++ K+L+ +FRL+LN G+D I + E+ HV+ Sbjct: 371 SQINPHFLYNTLDTIIWMAEFHDSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQ 430 Query: 242 YLIIQQMRYHDILEFKLEVAEELQEYPILNMTLQPLVENALYHGIKNKRGMGLIRIGGYT 301 YL IQ+ RY D LE+++ + + LQPLVENALYHGIK K G G I++ Sbjct: 431 YLFIQKQRYGDKLEYEINENVAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQK 490 Query: 302 DGGSIMLTVSDNGIGIPAGRLEILRESIEHPIQSEDTEDTGQ-----GGFGLQNVHQRLR 356 +++ + D+G+G +D D+ Q GG GLQNV QRL+ Sbjct: 491 QDSGLVIRIEDDGVGF------------------QDAGDSSQSQLKRGGVGLQNVDQRLK 532 Query: 357 LYFGPEYGIRLDSSEGYGTQITVRIPK 383 L+FG Y +++DS GT++ + I + Sbjct: 533 LHFGANYHMKIDSRPQKGTKVEIYINR 559 >BS_yesM [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 577 Score = 176 bits (447), Expect = 5e-44, Method: Compositional matrix adjust. Identities = 107/341 (31%), Positives = 178/341 (52%), Gaps = 20/341 (5%) Query: 46 GSFVLQTGGPPRFIVHTSSLATGWTIIGIAPLQEIVAEANRIRQLIIISVGLSIIFAIXX 105 G +++ G FI + S W+ + P ++ A+ + ++ +I L + Sbjct: 247 GYDLIKKNGKRYFISYLQSSYQNWSYYNVIPFDQMFAKISFMKTVIGTCFLLFFCVVLLF 306 Query: 106 XXXXXXXXXXPIQLLQHKMRLTASGYLEAKVK---PDGT-DEIADLGQSFNIMVEQIKEL 161 PI+ L M+ +EA V P+ T DE L + F +M+++I EL Sbjct: 307 GRKIANSITEPIEQLVTAMKSVQHSGIEAGVSLSLPEHTQDEAGMLNRHFTVMMKRINEL 366 Query: 162 LAQSIRKQQQLQKAELRTLQAQINPHFLYNTLDSIVWMAEAGNHDGVIRLVKALSAFFRL 221 + +++ KQ +++ EL+ LQAQINPHFLYNTL+SI W+A+A + ++V++L R Sbjct: 367 MEENVEKQLIIKETELKALQAQINPHFLYNTLESINWLAKANQQKQISKMVESLGFLLRN 426 Query: 222 SLNNGRDWIQIRSELAHVQSYLIIQQMRYHDILEFKLEVAEELQEYPILNMTLQPLVENA 281 S++ +D + I+ E V+ Y+ IQ+ R+ + L+F L++ +E++ I +TLQPL ENA Sbjct: 427 SIHMKKDIVTIQEEADIVRHYMTIQRFRFEERLKFTLDIDDEVKHCLIPKLTLQPLAENA 486 Query: 282 LYHGIKNKRGMGLIRIGGYTDGGSIMLTVSDNGIGIPAGRLEILRESIEHPIQSEDTEDT 341 + + ++ IRI G + +TV DNG G+ GR+ E T Sbjct: 487 IQYALEPFTRPCAIRIQAKKAKGCVCITVEDNGPGMD-GRI---------------LEST 530 Query: 342 GQGGFGLQNVHQRLRLYFGPEYGIRLDSSEGYGTQITVRIP 382 G G GL N+ +R+ L FG YG+R+ S GT+I + IP Sbjct: 531 GGRGIGLWNIRERISLTFGEPYGLRIHSEHEKGTRIVITIP 571 >BH2110 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 585 Score = 167 bits (424), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 99/327 (30%), Positives = 177/327 (54%), Gaps = 16/327 (4%) Query: 68 GWTIIGIAPLQEIVAEANRIRQLIIISVGLSIIF-AIXXXXXXXXXXXXPIQLLQHKMRL 126 GW + G EI+ E + R+ I+I ++++F + +++L+H R+ Sbjct: 263 GWRVAGTISENEILEELYKSREFIVILASINLLFPTLLIVLISKSIHSRLLRVLKHMKRM 322 Query: 127 TASGYLEAKVKPDGTDEIADLGQSFNIMVEQIKELL----AQSIRK---QQQLQKAELRT 179 + + P DEI +L FN M + I L+ A +I K Q + ++A+L Sbjct: 323 KKQKF-DIINFPGDKDEIGELTNEFNKMSQTINRLINEVYASNIEKKDLQLREKQAQLSA 381 Query: 180 LQAQINPHFLYNTLDSIVWMAEAGNHDGVIRLVKALSAFFRLSLNNGRDWIQIRSELAHV 239 LQ+QINPHFL+N L++I + ++++ ++ FR SL G+DW+ +R EL + Sbjct: 382 LQSQINPHFLFNALETIRMRSMIKGEKETAKIIQNMAKIFRNSLTWGKDWVTVRDELCLI 441 Query: 240 QSYLIIQQMRYHDILEFKLEVAEELQEYPILNMTLQPLVENALYHGIKNKRGMGLIRIGG 299 +L IQ+ R+ D +E++L++ EE +Y I NM P VENA HGI++ + G+I+I Sbjct: 442 ICFLEIQKYRFGDKMEYELDIDEEAYDYIIPNMVFLPFVENASIHGIESVKEKGIIQIRV 501 Query: 300 YTDGGSIMLTVSDNGIGIPAGRLEILRESIEHPIQSEDTEDTGQGGFGLQNVHQRLRLYF 359 + G I+ +SDNG G+ +L L E++ ++ E+ G+ G++NV+ RL+L++ Sbjct: 502 EKNDGEIVYEISDNGAGMDEEKLASLIETL------KNEENMGE-NVGIKNVYYRLKLHY 554 Query: 360 GPEYGIRLDSSEGYGTQITVRIPKNKG 386 + ++S G GT + +++P K Sbjct: 555 KNHFDFSINSRPGQGTTVQIKLPAEKN 581 >BH1909 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 597 Score = 155 bits (392), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 106/345 (30%), Positives = 179/345 (51%), Gaps = 18/345 (5%) Query: 53 GGPPRFIVHTSSLATGWT---IIGIAPLQEIVAEANRIRQL-IIISVGLSIIFAIXXXXX 108 G P + IV +L + II I + I+ +A R+ + +++G + A+ Sbjct: 256 GEPSQIIVDYLTLQMSQSELKIISIVTKEHIMKDAKRLSIMGATVTMG-GMAVAVLLIVH 314 Query: 109 XXXXXXXPIQLLQHKMRLTASGYLEAKVKPDGTDEIADLGQSFNIMVEQIKELLAQ---S 165 + L ++ ASG L+ K+ DG DEI L FN MV ++ L+ Q + Sbjct: 315 FSWLISKRLSHLSERINQVASGDLKTKIVVDGKDEIGQLSVQFNQMVANLRSLIHQVHET 374 Query: 166 IRKQQQLQKAE----LRTLQAQINPHFLYNTLDSIVWMAEAGNHDGVIRLVKALSAFFRL 221 R+++ L+K++ L+ L +QINPHFL+NTL+SI + + ++VK L R Sbjct: 375 NRQKRLLEKSQNEIKLKMLASQINPHFLFNTLESIRMKSHMKGETEIAKVVKQLGKLMRK 434 Query: 222 SLNNGRDWIQIRSELAHVQSYLIIQQMRYHDILEFKLEVAEELQEYPILNMTLQPLVENA 281 SL I +R+EL V+ YL IQ RY D L ++L + + + IL + +QPLVENA Sbjct: 435 SLEVTGHHIPLRNELDMVRCYLEIQTFRYGDRLHYELYIDPQSEMVEILPLIIQPLVENA 494 Query: 282 LYHGIKNKRGMGLIRIGGYTDGGSIMLTVSDNGIGIPAGRLEILRESIEHPIQSEDTEDT 341 + HG++ G + I +G + + V+D+G G+ +LE ++ + HP ++ Sbjct: 495 VIHGLERTEDGGTVTISTIVNGNDLTVIVNDDGCGMDEEKLEAIQNMLHHP------QEV 548 Query: 342 GQGGFGLQNVHQRLRLYFGPEYGIRLDSSEGYGTQITVRIPKNKG 386 GL NVH+RL+L +G G+ ++S++G GT + I + +G Sbjct: 549 DGNKIGLLNVHKRLQLTYGKTSGLIIESAKGKGTCVRFTISQIRG 593 >BH1122 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 586 Score = 148 bits (374), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 89/317 (28%), Positives = 160/317 (50%), Gaps = 15/317 (4%) Query: 67 TGWTIIGIAPLQEIVAEANRIRQLIIISVGLSIIFAIXXXXXXXXXXXXPIQLLQHKMRL 126 T WT+ + P E+ + R+ +++I + I+ A+ PI L++ + Sbjct: 268 TEWTLKQVTPYSELTEGSRRMAAILVIIGAIMIVVALLVTYSLTKKFTTPIYELKNVLSK 327 Query: 127 TASGYLEAKVKPDGTDEIADLGQSFNIMVEQIKELLAQSIRKQQQLQKAELRTLQAQINP 186 L ++ D +E +L + + ++ + EL R+ ++ ++AE++ LQA INP Sbjct: 328 YPDQDLSGELPSDYRNEFGELFEGYKGLIRRNNELYRSLHRQYKRQREAEIKALQANINP 387 Query: 187 HFLYNTLDSIVWMAEAGNHDGVIRLVKALSAFFRLSLNNGRDWIQIRSELAHVQSYLIIQ 246 HFLYNTLD + WMA + +++ L R+ L+NG + + E+ +++ YL IQ Sbjct: 388 HFLYNTLDQLNWMAIEKGDRTMSHMLENLGQMLRIGLSNGESILPLEKEVEYLKYYLKIQ 447 Query: 247 QMRYHDILEFKLEVAEELQEYPILNMTLQPLVENALYHGIKNKRGMGLIRIGGYTDGGSI 306 +++ + L + ++V L Y I +TLQP VEN HG ++ R G + I D I Sbjct: 448 KLKMGERLTYTVDVPVMLYRYLIPKLTLQPFVENCFIHGFQDGRD-GEVVIRAMEDQNHI 506 Query: 307 MLTVSDNGIGIPAGRLEILRESIEHPIQSEDTEDTGQGGFGLQNVHQRLRLYFGPEYGIR 366 ++T+ DNGIG P+ ++ ++ GG+G++NV +RL +YF + Sbjct: 507 VMTIQDNGIGF-------------QPVTTKRSK-LDMGGYGIRNVMERLDVYFDRYASVH 552 Query: 367 LDSSEGYGTQITVRIPK 383 + E GT + + IPK Sbjct: 553 VTGDEQGGTLVKIIIPK 569 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.139 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 27,735,348 Number of extensions: 1123317 Number of successful extensions: 2278 Number of sequences better than 1.0e-05: 26 Number of HSP's gapped: 2248 Number of HSP's successfully gapped: 26 Length of query: 387 Length of database: 38,378,431 Length adjustment: 108 Effective length of query: 279 Effective length of database: 25,922,359 Effective search space: 7232338161 Effective search space used: 7232338161 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 117 (49.7 bits)