BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0267.0019.p (256 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC2989 [L] COG0084 Mg-dependent DNase 215 6e-56 PM1675 [L] COG0084 Mg-dependent DNase 205 6e-53 AGc2756 [L] COG0084 Mg-dependent DNase 203 3e-52 VC2014 [L] COG0084 Mg-dependent DNase 196 3e-50 RSc1787 [L] COG0084 Mg-dependent DNase 195 8e-50 >CAC2989 [L] COG0084 Mg-dependent DNase Length = 253 Score = 215 bits (547), Expect = 6e-56, Method: Compositional matrix adjust. Identities = 113/248 (45%), Positives = 158/248 (63%), Gaps = 3/248 (1%) Query: 3 LFDTHTHLDAPQFDEDRAGVIARALEAGVSKMINIGFNRETIPTTMKLAETYDYIYAAVG 62 +FD H H D +F+EDR VI GV ++N G + E +++LAE YD+ YAAVG Sbjct: 2 IFDAHAHYDDDEFNEDRDKVINELKSNGVIGVLNCGSSMEGTLKSVELAEKYDFFYAAVG 61 Query: 63 WHPVDAIDMKEGDMDWIASLCSHKKVVAIGEIGLDYYWDTSP-KEVQHEVFRKQIGLARE 121 HP A E + I +L KV AIGEIGLDYY+D +P +EVQ +VF KQ+ LA + Sbjct: 62 IHPEYADKFDENTLKEIEALTKSSKVKAIGEIGLDYYYDENPPREVQKKVFIKQMELAEK 121 Query: 122 LKMPICIHNRDAHEDVVRILREEKANEIGGVMHSFSGSWETAKMCLDLGFHLSFGGPVTF 181 L +P+ IH+RDAH D + I+++ ++ G +H FSGS E AK CL LG++L F G VTF Sbjct: 122 LNLPVIIHDRDAHGDTLDIIKQ--FPKVKGEIHCFSGSVEFAKECLKLGYYLGFTGVVTF 179 Query: 182 KNARVPKEVLAQTPMDRLLIETDSPYLTPHPFRGKRNESAYVKLVAEAAAEIKGIDLQEL 241 KNA+ +V+ + P+D++L+ETD PY+ P P RGKRN S Y++ + E A+IK I + Sbjct: 180 KNAKKVVKVVREIPLDKILVETDCPYMAPVPNRGKRNRSEYIEYIVEKIADIKSILPINV 239 Query: 242 AEITYANA 249 E T +N Sbjct: 240 KEQTASNV 247 >PM1675 [L] COG0084 Mg-dependent DNase Length = 260 Score = 205 bits (521), Expect = 6e-53, Method: Compositional matrix adjust. Identities = 103/258 (39%), Positives = 150/258 (58%), Gaps = 4/258 (1%) Query: 1 MRLFDTHTHLDAPQFDEDRAGV---IARALEAGVSKMINIGFNRETIPTTMKLAETYDYI 57 M + D+H HLDA ++ + V + +A+E V ++ +G + + Sbjct: 1 MFIVDSHCHLDALDYENLHSSVDDVVNKAMEREVKHLLAVGVTLTRFEQIYATLAKFKNV 60 Query: 58 YAAVGWHPVDAIDMKEGDMDWIASLCSHKKVVAIGEIGLDYYWDTSPKEVQHEVFRKQIG 117 A G HP+D +D + D D + L KVVAIGE GLDYY+ K Q +F QI Sbjct: 61 SLACGVHPLD-LDDEPFDADRLLKLADDPKVVAIGETGLDYYYSAENKTTQQAIFANQIQ 119 Query: 118 LARELKMPICIHNRDAHEDVVRILREEKANEIGGVMHSFSGSWETAKMCLDLGFHLSFGG 177 +A +L P+ +H R A ED +R+L E A++ GGV+H F+ +W+ AK LDLG ++S G Sbjct: 120 IANQLNKPVIVHTRSAREDTIRLLAENHADKCGGVLHCFTENWDMAKKGLDLGLYISLSG 179 Query: 178 PVTFKNARVPKEVLAQTPMDRLLIETDSPYLTPHPFRGKRNESAYVKLVAEAAAEIKGID 237 +TFKNA ++V + P+DRLLIETDSPYL P P+RGK+N+ AYV+ V E A +KG+ Sbjct: 180 IITFKNAEEIRDVARRVPLDRLLIETDSPYLAPVPYRGKQNQPAYVREVCEYVATLKGVS 239 Query: 238 LQELAEITYANALERFGI 255 +E A++T N F I Sbjct: 240 FEEFAQLTTQNFERLFKI 257 >AGc2756 [L] COG0084 Mg-dependent DNase Length = 218 Score = 203 bits (516), Expect = 3e-52, Method: Compositional matrix adjust. Identities = 0/254 (0%), Positives = 0/254 (0%), Gaps = 2/254 (0%) Query: 3 LFDTHTHLDAPQFDEDRAGVIARALEAGVSKMINIGFNRETIPTTMKLAETYDYIYAAVG 62 + Q + +R + + + + + D Sbjct: 11 NRIIRSRQSMKQELILASSSASRQMLMRNAGLTFSAIPADIDERALDEQLERDGASPEEV 70 Query: 63 WHPVDAIDMKEGDMDWIASLC-SHKKVVAIGEIGLDYYWDTSPKEVQHEVFRKQIGLARE 121 + +L + +A+G + + ++ Sbjct: 71 ALELARAKALAVSALHPEALVLGCDQTMALGTRVYHKPKNMAEAATHLLSLSGKVHRLNS 130 Query: 122 LKMPICIHNRDAHEDVVRILREEKAN-EIGGVMHSFSGSWETAKMCLDLGFHLSFGGPVT 180 + + L + E G + + + Sbjct: 131 AAVLVHNGKVVWQTVSSAELAVRTLSAEFVSRHLQRVGEKALSSVGAYQLEREGIQLFTS 190 Query: 181 FKNARVPKEVLAQTPMDRLLIETDSPYLTPHPFRGKRNESAYVKLVAEAAAEIKGIDLQE 240 Sbjct: 191 250 Query: 241 LAEITYANALERFG 254 Sbjct: 251 264 >VC2014 [L] COG0084 Mg-dependent DNase Length = 255 Score = 196 bits (498), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 99/247 (40%), Positives = 148/247 (59%), Gaps = 5/247 (2%) Query: 5 DTHTHLDAPQFDE---DRAGVIARALEAGVSKMINIGFNRETIPTTMKLAETYDYIYAAV 61 D+H HLD + + D + V+ +A +A V ++++G ++ P + + E + +YA+ Sbjct: 4 DSHCHLDKLDYQDLHADVSDVLDKAHQAKVEYLLSVGVTLDSFPKMLAMIEPFSQVYASC 63 Query: 62 GWHPVDAIDMKEGDMDWIASLCSHKKVVAIGEIGLDYYWDTSPKEVQHEVFRKQIGLARE 121 G HP+D + +D H +VVAIGE GLDY++ ++Q FR+QI A Sbjct: 64 GVHPLDV--QSDFSLDLFHQYAQHPRVVAIGETGLDYHYQPETADLQKLRFRQQIETAVA 121 Query: 122 LKMPICIHNRDAHEDVVRILREEKANEIGGVMHSFSGSWETAKMCLDLGFHLSFGGPVTF 181 L P+ IH R+A +D +++LRE KA + GGV+H F+ A+ ++LGF++S G VTF Sbjct: 122 LNKPLIIHTRNAQQDTLQLLREGKAQQCGGVIHCFTEDLAFAQAAMELGFYISISGIVTF 181 Query: 182 KNARVPKEVLAQTPMDRLLIETDSPYLTPHPFRGKRNESAYVKLVAEAAAEIKGIDLQEL 241 + A KEV+ P+DRLLIETDSPYL P P RGK N+ AYV VA A +KG+ L E+ Sbjct: 182 RQATDLKEVVKALPLDRLLIETDSPYLAPVPHRGKENQPAYVVEVAAYIAALKGVSLTEV 241 Query: 242 AEITYAN 248 A+ T N Sbjct: 242 AQKTTQN 248 >RSc1787 [L] COG0084 Mg-dependent DNase Length = 267 Score = 195 bits (495), Expect = 8e-50, Method: Compositional matrix adjust. Identities = 106/262 (40%), Positives = 147/262 (56%), Gaps = 10/262 (3%) Query: 5 DTHTHLDAPQFDEDRAGVIARALEAGVSKMINIGFNRETIPTTMKLAETYDYIYAAVGWH 64 D+H H++ P ++A E V+ + I E P+ +++AE IYA VG H Sbjct: 4 DSHCHINFPDLRARLPELLAHMRENRVTHALCISVTLEDFPSVLEIAEQEPNIYATVGVH 63 Query: 65 PVDAIDMKEGD------MDWIASLCSHKKVVAIGEIGLDYYW----DTSPKEVQHEVFRK 114 P D++EG ++ + +L H +VV IGE GLDYY + E Q E FR Sbjct: 64 PDAEADLEEGTRIEEPTLERLLALADHPRVVGIGETGLDYYRLNGRSVADMEWQRERFRT 123 Query: 115 QIGLARELKMPICIHNRDAHEDVVRILREEKANEIGGVMHSFSGSWETAKMCLDLGFHLS 174 I +R+ P+ IH R A +D + I+REE A GVMH F+ +W+ AK LDLGF++S Sbjct: 124 HIRASRQTGKPLVIHTRSAADDTLAIMREEGAEAARGVMHCFTETWDVAKAALDLGFYIS 183 Query: 175 FGGPVTFKNARVPKEVLAQTPMDRLLIETDSPYLTPHPFRGKRNESAYVKLVAEAAAEIK 234 F G VTFK+A +E + P+DR+LIETDSPYL P PFRGK NE AYV+ V E A ++ Sbjct: 184 FSGIVTFKSAADLQETARKVPLDRMLIETDSPYLAPVPFRGKTNEPAYVRHVGECLATLR 243 Query: 235 GIDLQELAEITYANALERFGIV 256 G L+ +A T N F + Sbjct: 244 GEPLEHIASATTENFFRLFNAI 265 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.137 0.412 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 19,435,545 Number of extensions: 817601 Number of successful extensions: 1393 Number of sequences better than 1.0e-05: 50 Number of HSP's gapped: 1308 Number of HSP's successfully gapped: 50 Length of query: 256 Length of database: 38,378,431 Length adjustment: 104 Effective length of query: 152 Effective length of database: 26,383,695 Effective search space: 4010321640 Effective search space used: 4010321640 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 114 (48.5 bits)