BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0266.0009.p (293 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0023 [K] COG0583 Transcriptional regulator 172 7e-43 mll2048 [K] COG0583 Transcriptional regulator 134 1e-31 sll0998 [K] COG0583 Transcriptional regulator 125 1e-28 all3953 [K] COG0583 Transcriptional regulator 124 1e-28 BH2094 [K] COG0583 Transcriptional regulator 124 3e-28 >CAC0023 [K] COG0583 Transcriptional regulator Length = 299 Score = 172 bits (435), Expect = 7e-43, Method: Compositional matrix adjust. Identities = 96/283 (33%), Positives = 160/283 (56%), Gaps = 2/283 (0%) Query: 1 MRTFREVAKRQSFTRAAEELGYAQSSVTMQIQKIEKEYGVPLIERHGRALRLTPPGEELL 60 + TF V+K QSFT AA L YAQS+VT QI+ +E+E + L ER G+ + LT G++LL Sbjct: 6 LNTFIAVSKYQSFTEAAHSLNYAQSTVTTQIKILEEELQIKLFERIGKKVTLTYEGKKLL 65 Query: 61 KLFVEILDLYDRSKETI--AQQIGGTLTIGTIDSLAAFYLPPFLQQLRTTFPGLNIHLQT 118 +++ L + K+ + ++ GTLTIG +SL LP L++ R +P + + L+ Sbjct: 66 PYAKQMIKLSNEIKKVVLDDEKPSGTLTIGAAESLCVIRLPEILKEYRRLYPDVEVSLKF 125 Query: 119 EQEANLVAKIRDGEVDIGLMLDRSTTDSQLERMIIRDEPLVLVAPKGHPLAKLDGVTLHD 178 A+ ++D +D+ L ++ + DEP++L+A HPL K + + D Sbjct: 126 GSCADFRHFLKDNIIDVAFSLGTKIDSNEFISEVEFDEPMILLAYPDHPLVKKEKIYPED 185 Query: 179 LNQCELIVSEESCIYRSLFENLLREHGINFRIGFELSNLEAIKRCVRNGLGIALLPRIVA 238 + + L+++E C YR+ FEN+LR + I ++ E +++AIK+ + LGI LLP++ Sbjct: 186 IVEEPLVLTEMGCSYRAAFENILRSYNIKPKLVLETGSVQAIKQFTMSRLGITLLPKVAV 245 Query: 239 EEEIERGTLAELAFVHPEIHFDLQLLIHPKKWKSLPLQSLIQM 281 EEEI+ G L L + P+ Q+L H KW S L + +++ Sbjct: 246 EEEIKNGKLIPLNWCGPDFGIISQVLYHKDKWISPALNAFLKL 288 >mll2048 [K] COG0583 Transcriptional regulator Length = 329 Score = 134 bits (338), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 86/261 (32%), Positives = 130/261 (49%), Gaps = 12/261 (4%) Query: 1 MRTFREVAKRQSFTRAAEELGYAQSSVTMQIQKIEKEYGVPLIERHGRALRLTPPGEELL 60 ++TF VA+ ++ TRAAE + AQSSV+ QIQ +E E G L R L LTP G L+ Sbjct: 6 LKTFLAVARSRNITRAAEAVHLAQSSVSDQIQTLEAELGAALFTRSKSGLELTPAGLALM 65 Query: 61 KLFVEILDLYDRSKETIAQQIG---GTLTIGTIDSLAAFYLPPFLQQLRTTFPGLNIHLQ 117 + E+L L ++ + G G LTIG ++++AA L P+L + P + + ++ Sbjct: 66 PIAEELLRLDGEARAAVLAAAGRTSGALTIGALETIAAARLAPWLPGFQAGHPDITVRMK 125 Query: 118 TEQEANLVAKIRDGEVDIGLMLD-----RSTTDSQLERMIIRDEPLVLVAPKGHPLAKLD 172 L + DG++D+ + R D +L R I EPLVLVA G LA Sbjct: 126 VADSGTLRRLLEDGDIDVAFCFERRDGARGAADGRLARRTIGAEPLVLVAAPGQALAP-- 183 Query: 173 GVTLHDLNQCELIVSEESCIYRSLFENLLREHGIN-FRIGFELSNLEAIKRCVRNGLGIA 231 L DL + +E CIYR + + E + + E+ ++ AI R V G G+ Sbjct: 184 -GGLADLAALRFVATEPGCIYRHMLDTAFAEADMAPPKPAAEVGSIGAIARLVATGAGLG 242 Query: 232 LLPRIVAEEEIERGTLAELAF 252 L+PR+ + RG L EL + Sbjct: 243 LIPRLAVSGALARGELVELPW 263 >sll0998 [K] COG0583 Transcriptional regulator Length = 345 Score = 125 bits (313), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 82/291 (28%), Positives = 147/291 (50%), Gaps = 8/291 (2%) Query: 1 MRTFREVAKRQSFTRAAEELGYAQSSVTMQIQKIEKEYGVPLIERHGRALRLTPPGEELL 60 +R + +A SF RAA+ L +Q +V++Q+Q +EK+ VPL +R GR +LT G LL Sbjct: 11 LRILKAIASEGSFKRAADTLYVSQPAVSLQVQNLEKQLSVPLFDRGGRKAQLTEAGHLLL 70 Query: 61 KLFVEILDLYD---RSKETIAQQIGGTLTIGTIDSLAAFYLPPFLQQLRTTFPGLNIHLQ 117 +I+ L R+ E + GGTL +G + + LP + R +P + + LQ Sbjct: 71 NYGEKIITLCQETCRAIEDLQNLQGGTLIVGASQTTGTYLLPRMIGMFRQQYPDVTVQLQ 130 Query: 118 TEQEANLVAKIRDGEVDIGLMLDRSTTDSQ--LERMIIRDEPLVLVAPKGHPLAKLDGVT 175 + +G+VD+ ++ + Q L + ++ L L+ P HPLA+ + + Sbjct: 131 VHSTRRTAWGVANGQVDLAIIGGEVPAELQETLTVLPYAEDELALILPVLHPLAQAETIQ 190 Query: 176 LHDLNQCELIVSEESCIYRSLFENLLREHGIN---FRIGFELSNLEAIKRCVRNGLGIAL 232 DL + + I + R + + +L + I+ +I EL+++EAIK V++GLG A Sbjct: 191 KEDLYKLKFISLDSQSTIRKVIDKVLSQGEIDTKRLKIEMELNSIEAIKNAVQSGLGAAF 250 Query: 233 LPRIVAEEEIERGTLAELAFVHPEIHFDLQLLIHPKKWKSLPLQSLIQMLL 283 + E+E+E L + EI L ++I+P +++S + I+ +L Sbjct: 251 VSTTAIEKELEMNVLHIAPIKNVEIRRVLSVIINPNRYRSKASAAFIREVL 301 >all3953 [K] COG0583 Transcriptional regulator Length = 337 Score = 124 bits (312), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 85/292 (29%), Positives = 144/292 (49%), Gaps = 10/292 (3%) Query: 1 MRTFREVAKRQSFTRAAEELGYAQSSVTMQIQKIEKEYGVPLIERHGRALRLTPPGEELL 60 +R + +A SF RAA+ L +Q +V++Q+Q +E++ VPL +R GR +LT G LL Sbjct: 11 LRILKAIAVEGSFKRAADSLYVSQPAVSLQVQNLERQLDVPLFDRGGRRAQLTEAGHLLL 70 Query: 61 KLFVEILDLYD---RSKETIAQQIGGTLTIGTIDSLAAFYLPPFLQQLRTTFPGLNIHLQ 117 +IL L R+ E + GGTL +G + + LP + R +P + + L Sbjct: 71 SYGEKILSLCQETCRAIEDLQNLQGGTLIVGASQTTGTYLLPKMIGMFRQKYPDVAVQLH 130 Query: 118 TEQEANLVAKIRDGEVD---IGLMLDRSTTDSQLERMIIRDEPLVLVAPKGHPLAKLDGV 174 + +G+VD IG + T+S LE + ++ L L+ P HP KLD + Sbjct: 131 VHSTRRTAWSVANGQVDLAIIGGEIPGELTES-LEIIPYAEDELALILPVFHPFTKLDTI 189 Query: 175 TLHDLNQCELIVSEESCIYRSLFENLLREHGIN---FRIGFELSNLEAIKRCVRNGLGIA 231 DL + + I + R + + +L I+ F+I EL+++EAIK V++GLG A Sbjct: 190 QKEDLYKLQFITLDSQSTIRKVIDQVLSRSEIDTRRFKIEMELNSIEAIKNAVQSGLGAA 249 Query: 232 LLPRIVAEEEIERGTLAELAFVHPEIHFDLQLLIHPKKWKSLPLQSLIQMLL 283 + +E++ G L I L L+ +P +++S ++ Q +L Sbjct: 250 FVSTSAIAKELQMGVLHCTPIDGVVIKRTLWLIFNPNRYRSKAAEAFSQEIL 301 >BH2094 [K] COG0583 Transcriptional regulator Length = 232 Score = 124 bits (310), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 66/220 (30%), Positives = 119/220 (54%), Gaps = 3/220 (1%) Query: 50 LRLTPPGEELLKLFVEILDLYDRSKETIAQQIGGTLTIGTIDSLAAFYLPPFLQQLRTTF 109 ++ TP GE L + +IL L+ S + +Q T++IGTI++L + LP L+Q + + Sbjct: 1 MKPTPSGELLYEYAEKILSLHQESHMALQKQEIKTISIGTIETLVIYCLPRILEQFKEQY 60 Query: 110 PGLNIHLQTEQEANLVAKIRDGEVDIGLMLDRSTTDSQLERMIIRDEPLVLVAPKGHPLA 169 P + I + + E N++ ++ D E+D G +LD ++E + I+ E + +V P H Sbjct: 61 PDVLIRIIPDCEENIIRRVNDKEIDFGFILDSPCIVPEIESLSIQKERMAVVVPFNHLFE 120 Query: 170 KLDGVTLHDLNQCELIVSEESCIYRSLFENLLREHGINFRIGFELSNLEAIKRCVRNGLG 229 + +TL+DL L+++E+ C YR+ L++HG+ + + ELS++E IK+ V+N G Sbjct: 121 NREAITLNDLENQSLLLTEKGCTYRAFLLEKLKKHGVPYNVSMELSSVETIKKAVQNEWG 180 Query: 230 IALLPRIVAEEEIERGTLAELAFVHPEIHFDLQLLIHPKK 269 I LP + + + F + E F QL+ +K Sbjct: 181 IGFLPDYTIAHD---DPVKAIHFANEEFDFYRQLIYKKEK 217 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.139 0.392 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 20,169,221 Number of extensions: 816781 Number of successful extensions: 4779 Number of sequences better than 1.0e-05: 1529 Number of HSP's gapped: 3299 Number of HSP's successfully gapped: 1529 Length of query: 293 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 187 Effective length of database: 26,153,027 Effective search space: 4890616049 Effective search space used: 4890616049 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 115 (48.9 bits)