BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0264.0043.p (368 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2566 [D] COG0772 Bacterial cell division membrane protein 290 2e-78 BS_spoVE [D] COG0772 Bacterial cell division membrane protein 270 4e-72 BH3276 [D] COG0772 Bacterial cell division membrane protein 189 5e-48 STM0127 [D] COG0772 Bacterial cell division membrane protein 164 2e-40 ftsW [D] COG0772 Bacterial cell division membrane protein 162 6e-40 >BH2566 [D] COG0772 Bacterial cell division membrane protein Length = 366 Score = 290 bits (743), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 154/365 (42%), Positives = 199/365 (54%) Query: 4 MNKSRHAPDIWILMVILSLLAIGMVMVYSAGSVLGFRNYGDSFYFVKRQXXXXXXXXXXM 63 M + + APD +++ ++LL IG++MVYSA + D F+F KRQ M Sbjct: 1 MPRQKAAPDYLLVVATVALLIIGLIMVYSASEAWATYRFDDGFFFAKRQLFFASVGFIAM 60 Query: 64 FVTANTDYLVLKKLARPAXXXXXXXXXXXXXXXXXXXXXXARSWLGISSFGIQPSEFMKM 123 +Y + A+ ARSWLG+ +F IQPSEFMKM Sbjct: 61 LFMMRVEYWTWRVWAKLMVIVCFVLLIIVLIPGVGLVRGGARSWLGVGAFSIQPSEFMKM 120 Query: 124 GMILYLANWLGKEDYDISTFTRGLLPPLALIGSAFALIMMQPDLGTGTVMFGAALMMVFT 183 MI++LA +L + I++F +GLLP L+L+ AF +IM+QPDLGTG VM G ++M+F Sbjct: 121 AMIVFLAKFLAENQKLITSFKKGLLPSLSLVMLAFGMIMLQPDLGTGAVMVGTCVVMIFV 180 Query: 184 AGARMKHXXXXXXXXXXXXXXXXXXXPYRLQRITAFLDPWSDPLGAGYQIIQSLYAIXXX 243 AGAR+ H PYR++RIT+FLDPWSDPLG+G+QIIQSLYAI Sbjct: 181 AGARILHFVMLGIVGMAGFAALIISAPYRIKRITSFLDPWSDPLGSGFQIIQSLYAIGPG 240 Query: 244 XXXXXXXXMSRQKYSYVPEPQTDFIFSILAEEXXXXXXXXXXXXXXXXXWRGMKVAMSLP 303 SRQKY Y+PEPQTDFIF+IL+EE WRG+++A+ P Sbjct: 241 GLLGLGLGESRQKYYYLPEPQTDFIFAILSEELGFLGGCFVIALFGIVLWRGIRIALGAP 300 Query: 304 DRFGSYLAVGIVCMXXXXXXXXXXXXXGLMPVTGITLPLISYGGSSXXXXXXXXXXXXXX 363 D FGS+LA GIV M GLMPVTGITLPL+SYGGSS Sbjct: 301 DLFGSFLATGIVAMVAIQVMINIGVVTGLMPVTGITLPLLSYGGSSLTLMLVSLGVLLNV 360 Query: 364 SRYAR 368 SRY R Sbjct: 361 SRYTR 365 >BS_spoVE [D] COG0772 Bacterial cell division membrane protein Length = 366 Score = 270 bits (689), Expect = 4e-72, Method: Compositional matrix adjust. Identities = 146/365 (40%), Positives = 204/365 (55%) Query: 4 MNKSRHAPDIWILMVILSLLAIGMVMVYSAGSVLGFRNYGDSFYFVKRQXXXXXXXXXXM 63 M + +PD+ ++++ L LL IG++MVYSA +V + DSF+F KRQ M Sbjct: 1 MTTKKTSPDLLLVIITLLLLTIGLIMVYSASAVWADYKFDDSFFFAKRQLLFAGIGVIAM 60 Query: 64 FVTANTDYLVLKKLARPAXXXXXXXXXXXXXXXXXXXXXXARSWLGISSFGIQPSEFMKM 123 F N DY + ++ +RSW+G+ +F IQPSEFMK+ Sbjct: 61 FFIMNVDYWTWRTWSKLLMVICFFLLVLVLIPGVGMVRNGSRSWIGVGAFSIQPSEFMKL 120 Query: 124 GMILYLANWLGKEDYDISTFTRGLLPPLALIGSAFALIMMQPDLGTGTVMFGAALMMVFT 183 MI +LA +L ++ +I++F RG +P L ++ SAF +IM QPDLGTGTVM G ++M+F Sbjct: 121 AMIAFLAKFLSEKQKNITSFRRGFVPALGIVFSAFLIIMCQPDLGTGTVMVGTCIVMIFV 180 Query: 184 AGARMKHXXXXXXXXXXXXXXXXXXXPYRLQRITAFLDPWSDPLGAGYQIIQSLYAIXXX 243 AGAR+ H PYR++RIT++L+PW DPLG+G+QIIQSLYA+ Sbjct: 181 AGARIAHFVFLGLIGLSGFVGLVLSAPYRIKRITSYLNPWEDPLGSGFQIIQSLYAVGPG 240 Query: 244 XXXXXXXXMSRQKYSYVPEPQTDFIFSILAEEXXXXXXXXXXXXXXXXXWRGMKVAMSLP 303 SRQK+ Y+PEPQTDFIF+IL+EE WRG+++A+ P Sbjct: 241 GLFGMGLGQSRQKFFYLPEPQTDFIFAILSEELGFIGGTLILLLFSVLLWRGIRIALGAP 300 Query: 304 DRFGSYLAVGIVCMXXXXXXXXXXXXXGLMPVTGITLPLISYGGSSXXXXXXXXXXXXXX 363 D +GS++AVGI+ M GL+PVTGITLP +SYGGSS Sbjct: 301 DLYGSFVAVGIISMIAIQVMINIGVVTGLIPVTGITLPFLSYGGSSLTLMLMAVGVLLNV 360 Query: 364 SRYAR 368 SRY+R Sbjct: 361 SRYSR 365 >BH3276 [D] COG0772 Bacterial cell division membrane protein Length = 381 Score = 189 bits (481), Expect = 5e-48, Method: Compositional matrix adjust. Identities = 124/347 (35%), Positives = 167/347 (48%), Gaps = 3/347 (0%) Query: 4 MNKSRHAPDIWILMVILSLLA-IGMVMVYSAGSVLGFRNYGDSFYFVKRQXXXXXXXXXX 62 M S + W+L++ LLA G+VM++SA L R YGD +YF+KRQ Sbjct: 1 MKYSFTKDNDWVLIITTFLLAAFGLVMIFSASYALALREYGDFYYFLKRQSMWLGIGTVA 60 Query: 63 MFVTANTDYLVLKKLARPAXXXXXXXXXXXXXXXXXXXXXXARSWLGISSFGIQPSEFMK 122 + Y KKL P A+ WL I F +QPSEF+K Sbjct: 61 FLFLMHFPYRFYKKLMIP--ILIVSFALLVLVIYFGVEGNGAQRWLIIGPFTLQPSEFVK 118 Query: 123 MGMILYLANWLGKEDYDISTFTRGLLPPLALIGSAFALIMMQPDLGTGTVMFGAALMMVF 182 +G+I+YLA K+ I+ F G++PPL ++G F LIM QPDLGT T + ++VF Sbjct: 119 LGVIVYLAAVYSKKQAYINKFITGVMPPLVVVGLVFVLIMRQPDLGTATSILIVTALIVF 178 Query: 183 TAGARMKHXXXXXXXXXXXXXXXXXXXPYRLQRITAFLDPWSDPLGAGYQIIQSLYAIXX 242 +GA+ +H YRL R+TAF++P+SD G GYQ+IQS AI Sbjct: 179 FSGAKWRHLIALGVVGVTLFVQYATSEQYRLARLTAFVNPFSDQSGTGYQLIQSYLAIAN 238 Query: 243 XXXXXXXXXMSRQKYSYVPEPQTDFIFSILAEEXXXXXXXXXXXXXXXXXWRGMKVAMSL 302 S QK +Y+PE TDFI +I+AEE +RG+ + Sbjct: 239 GGLTGTGLGQSIQKLAYLPEAHTDFILAIIAEELGFFGVAFVFLCYGMILFRGVVIGTRC 298 Query: 303 PDRFGSYLAVGIVCMXXXXXXXXXXXXXGLMPVTGITLPLISYGGSS 349 FGS LA GIV GL+P+TGI LPL+S GGSS Sbjct: 299 KSPFGSLLAFGIVFQLAVQVVFNIGAVTGLLPITGIPLPLVSNGGSS 345 >STM0127 [D] COG0772 Bacterial cell division membrane protein Length = 414 Score = 164 bits (416), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 108/341 (31%), Positives = 149/341 (43%), Gaps = 5/341 (1%) Query: 12 DIWILMVILSLLAIGMVMVYSAGSVLGFRNYGDSFYFVKRQXXXXXXXXXXMFVTANTDY 71 D +L + L AIG VMV SA +G R D F F KR VT Sbjct: 45 DRTLLWLTFGLAAIGFVMVTSASMPVGQRLANDPFLFAKRDALYIFLAFCLAMVTLRLPM 104 Query: 72 LVLKKLARPAXXXXXXXXXXXXXXXXXXXXXXARSWLGISSFGIQPSEFMKMGMILYLAN 131 +K + A W+ + IQP+EF K+ + YLAN Sbjct: 105 TFWQKYS--TTMLIASIIMLLIVLVVGSSVNGASRWIALGPLRIQPAEFTKLSLFCYLAN 162 Query: 132 WLGKEDYDISTFTRGLLPPLALIGSAFALIMMQPDLGTGTVMFGAALMMVFTAGARMKHX 191 +L ++ ++ RG L P+ +I L++ QPDLGT V+F L M+F AGA++ Sbjct: 163 YLVRKVDEVRNNLRGFLKPMGVILVLAVLLLAQPDLGTVVVLFVTTLAMLFLAGAKLWQF 222 Query: 192 XXXXXXXXXXXXXXXXXXPYRLQRITAFLDPWSDPLGAGYQIIQSLYAIXXXXXXXXXXX 251 PYR++R+T+F +PW DP G+GYQ+ QSL A Sbjct: 223 IAIIGMGISAVILLILAEPYRIRRVTSFWNPWEDPFGSGYQLTQSLMAFGRGEIWGQGLG 282 Query: 252 MSRQKYSYVPEPQTDFIFSILAEEXXXXXXXXXXXXXXXXXWRGMKV---AMSLPDRFGS 308 S QK Y+PE TDFIF+I+ EE +R M + A+ + RF Sbjct: 283 NSVQKLEYLPEAHTDFIFAIIGEELGYIGVVLALLMVFFVAFRAMSIGRKALEIDHRFSG 342 Query: 309 YLAVGIVCMXXXXXXXXXXXXXGLMPVTGITLPLISYGGSS 349 +LA I G++P G+TLPLISYGGSS Sbjct: 343 FLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSS 383 >ftsW [D] COG0772 Bacterial cell division membrane protein Length = 331 Score = 162 bits (411), Expect = 6e-40, Method: Compositional matrix adjust. Identities = 0/341 (0%), Positives = 0/341 (0%), Gaps = 5/341 (1%) Query: 12 DIWILMVILSLLAIGMVMVYSAGSVLGFRNYGDSFYFVKRQXXXXXXXXXXMFVTANTDY 71 L A + +G + + Q Sbjct: 45 TSLTQQQRAELWAGIRHDIGLSGDSPLLSRHFPAAEHNLAQRLLAAQKSHSARQLLAQLG 104 Query: 72 LVLKKLARPAXXXXXXXXXXXXXXXXXXXXXXARSWLGISSFGIQPSEFMKMGMILYLAN 131 L+ + ++ + Sbjct: 105 EYLRLGN--NRQAVTDYIRHNFGQTPLNQLSPEQLKTILTLLQEGKMVIPQPQQREATDR 162 Query: 132 WLGKEDYDISTFTRGLLPPLALIGSAFALIMMQPDLGTGTVMFGAALMMVFTAGARMKHX 191 L +++ L S M G A + Sbjct: 163 PLLPAEHNALKQLVTKLAAATGEPSKQIWQSMLELSGVKDGELIPAKLFNHLVTWLQARQ 222 Query: 192 XXXXXXXXXXXXXXXXXXPYRLQRITAFLDPWSDPLGAGYQIIQSLYAIXXXXXXXXXXX 251 A L + A Sbjct: 223 TLSQQNTPTLESLQMTLKQPLDASELAALSAYIQQKYGLSAQSSLSSAQAEDILNQLYQR 282 Query: 252 MSRQKYSYVPEPQTDFIFSILAEEXXXXXXXXXXXXXXXXXWRGMKV---AMSLPDRFGS 308 + V +P + ++ + + Sbjct: 283 RVKGIDPRVMQPLLNPFPPMMDTLQNMATRPALWILLVAIILMLVWL 342 Query: 309 YLAVGIVCMXXXXXXXXXXXXXGLMPVTGITLPLISYGGSS 349 Sbjct: 343 383 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.327 0.140 0.429 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 18,075,053 Number of extensions: 478524 Number of successful extensions: 1363 Number of sequences better than 1.0e-05: 78 Number of HSP's gapped: 1167 Number of HSP's successfully gapped: 83 Length of query: 368 Length of database: 38,378,431 Length adjustment: 108 Effective length of query: 260 Effective length of database: 25,922,359 Effective search space: 6739813340 Effective search space used: 6739813340 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 116 (49.3 bits)