BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0264.0030.p
         (230 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NMA0493 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins       149   4e-36
RSc2683 [R] COG0325 Predicted enzyme with a TIM-barrel fold           119   5e-27
RSp0683 [R] COG0325 Predicted enzyme with a TIM-barrel fold           114   2e-25

>NMA0493 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins
          Length = 216

 Score =  149 bits (376), Expect = 4e-36,   Method: Compositional matrix adjust.
 Identities = 79/205 (38%), Positives = 119/205 (58%), Gaps = 2/205 (0%)

Query: 24  DVADVKVIAVTKYVSLETVSAVLEAGLEDIAESRWQDAEPKWNALGHKGTWHFIGHLQTN 83
           ++    ++ VTK +  E ++  + AG   I E+R Q+ E K + +    T H IGHLQTN
Sbjct: 13  EIGSTTLVCVTKTIEPERINEAIRAGAPIIGENRVQEYEDKRDDILPCET-HLIGHLQTN 71

Query: 84  KVKDVIGKFQYIHSLDRLSLARELHKKADAAGITVNVFLQVNISGEDTKFGLAPGDVPGF 143
           KVK  +  F  I S+D + + R++ ++A   G    V+LQVNI  E  K+G  P ++   
Sbjct: 72  KVKKAVHLFDVIQSIDSMKIIRDIDRRARDIGKVQKVYLQVNIGNEPQKYGFGPDEIKNA 131

Query: 144 LHEIASLHRIKVIGLMTMAPYEAEPEQTRPVFRGLRELRDKLNLLALTPEPIQELSMGMS 203
           + EI SL  ++V GLM + P+   PEQTRP F+ ++ L D++         I+ LSMGMS
Sbjct: 132 ITEIRSLRNVRVEGLMCIPPF-VPPEQTRPYFKKMKALFDEMKQENRDNIDIRTLSMGMS 190

Query: 204 NDFEVAIEEGATWVRLGTVLVGHEE 228
            D+ +AIEEGAT VR+G+ + G  E
Sbjct: 191 GDYRIAIEEGATMVRVGSAIFGKRE 215


>RSc2683 [R] COG0325 Predicted enzyme with a TIM-barrel fold
          Length = 240

 Score =  119 bits (297), Expect = 5e-27,   Method: Compositional matrix adjust.
 Identities = 84/232 (36%), Positives = 124/232 (53%), Gaps = 11/232 (4%)

Query: 7   IAGVEERVARACAASGRDVADVKVIAVTKYVSLETVSAVLEAGLEDIAESRWQDAEPKWN 66
           +  V +R+  AC  + RD A V ++AV+K    + V A   AG     E+  Q+   K +
Sbjct: 8   LQAVRQRITTACTLASRDPASVTLLAVSKTFDADAVRAAHAAGQRLFGENYVQEGTAKTS 67

Query: 67  AL-----GHKG-TWHFIGHLQTNKVKDVIGKFQYIHSLDRLSLARELHKKADAAGITVNV 120
           AL     G +   WHFIG LQ+NK + V   F ++HS+DRL +A  L  +  A    + V
Sbjct: 68  ALTDLRNGPEAIAWHFIGPLQSNKTRAVAEHFDWVHSIDRLKIAERLSAQRPATLPPLQV 127

Query: 121 FLQVNISGEDTKFGLAP--GDVPGFLHEIASLHRIKVIGLMTMAPYEAEPEQTRPVFRGL 178
            L++NIS + +K G+ P   +V      +A+L R+++ GLM +     +P   R  F  L
Sbjct: 128 CLEINISRQASKHGVPPDLDEVLPLARAVAALPRLRLRGLMAVPEPADDPAARRAPFAAL 187

Query: 179 RELRDKLNLLALTPEPIQELSMGMSNDFEVAIEEGATWVRLGTVLVGHEEGA 230
           R+L D+L    L   P+  LSMGMS D E AI EGAT VR+G+ + G  + A
Sbjct: 188 RDLADRLCAAGL---PVDTLSMGMSADLEDAIAEGATIVRVGSAIFGARQYA 236


>RSp0683 [R] COG0325 Predicted enzyme with a TIM-barrel fold
          Length = 226

 Score =  114 bits (284), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 72/228 (31%), Positives = 113/228 (49%), Gaps = 14/228 (6%)

Query: 1   LTLQERIAGVEERVARACAASGRDVADVKVIAVTKYVSLETVSAVLEAGLEDIAESRWQD 60
             L++ I  + + +  A   +GR    V ++A +K V    +   ++ GL    E+R Q+
Sbjct: 3   CNLEDNIGRIRKAIQHAAIDNGRRADAVTLVAASKTVESHRIQKAIDLGLTVFGENRVQE 62

Query: 61  AEPKWNALGHKGT---WHFIGHLQTNKVKDVIGKFQYIHSLDRLSLARELHKKADAAGIT 117
           A  KW  L  +      H IG LQ+NKV+  +  F  I S+DR  LAR + ++A+  G  
Sbjct: 63  AVSKWPELRSRNPGIELHLIGPLQSNKVRQAVDLFDVIESVDRSRLARAIAEEAERQGHA 122

Query: 118 VNVFLQVNISGEDTKFGLAPGDVPGFLHEIASLHRIKVIGLMTMAPYEAEPEQTRPVFRG 177
             +++QVN+  E  K G+ P +    + E   ++++ V GLM + P   +P      F G
Sbjct: 123 PAIYIQVNVGKEPQKGGVLPAEASALIGECRDVYQLNVQGLMCIPPAGLDPSGH---FAG 179

Query: 178 LRELRDKLNLLALTPEPIQELSMGMSNDFEVAIEEGATWVRLGTVLVG 225
           LR +     L          LSMGMS D+  AI +GAT VR+G+ L G
Sbjct: 180 LRSIAADHGL--------HVLSMGMSADYPQAIAQGATHVRVGSALFG 219


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.318    0.135    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 17,276,157
Number of extensions: 772930
Number of successful extensions: 1332
Number of sequences better than 1.0e-05: 3
Number of HSP's gapped: 1324
Number of HSP's successfully gapped: 3
Length of query: 230
Length of database: 38,378,431
Length adjustment: 103
Effective length of query: 127
Effective length of database: 26,499,029
Effective search space: 3365376683
Effective search space used: 3365376683
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 114 (48.5 bits)