BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0264.0018.p (302 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Cgl1365 [E] COG0078 Ornithine carbamoyltransferase 82 1e-15 PA3537 [E] COG0078 Ornithine carbamoyltransferase 80 3e-15 SMc02137 [E] COG0078 Ornithine carbamoyltransferase 73 6e-13 L0109 [E] COG0078 Ornithine carbamoyltransferase 70 4e-12 ML0109 [C] COG0277 FAD/FMN-containing dehydrogenases 70 4e-12 >Cgl1365 [E] COG0078 Ornithine carbamoyltransferase Length = 319 Score = 81.6 bits (200), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 82/310 (26%), Positives = 134/310 (43%), Gaps = 29/310 (9%) Query: 10 RSLLGIKELDRTEILQLLNRTAYWDNQAEKLTPVLRSHFVANMFFENSTRTRFSFEMAEK 69 R L +L E ++L A P+ VA +F + STRTRFSF+ Sbjct: 8 RHFLADDDLTPAEQAEVLTLAAKLKAAPFSERPLEGPKSVAVLFDKTSTRTRFSFDAGIA 67 Query: 70 RLGVQVLNFTAAASSVEKGESIYDTVRTLESMGIDAGVVRLKPAGVLQQLAEKVSIPLIN 129 LG + + +S + KGES+ DT L S ++A V R +AE ++PL+N Sbjct: 68 HLGGHAIVVDSGSSQMGKGESLQDTAAVL-SRYVEAIVWRTYAHSNFHAMAETSTVPLVN 126 Query: 130 AGDGNNEHPTQALLDLYTMSKNFGE------LKGLKVSIIGDIMHSRVARSNLWGLTKMG 183 + ++ HP Q L DL T+ +N LKG K +GD + +A S + G G Sbjct: 127 SL-SDDLHPCQILADLQTIVENLSPEEGPAGLKGKKAVYLGD-GDNNMANSYMIGFATAG 184 Query: 184 AKVQFCAPDNMKAPELAEFAPYV---------------TMEEALKADVVMM-LRVQLERH 227 + AP+ + AEF +++E ADVV+ V + Sbjct: 185 MDISIIAPEGFQ--PRAEFVERAEKRGQETGAKVVVTDSLDEVAGADVVITDTWVSMGME 242 Query: 228 ATGILQSADEYRKQFGLTEERAAKLDKNTIIMHPAPVNRNVEIDDAVVESDKSRIFPQMA 287 GI ++ Q + +E AK + I +H P R E+ +V++ S++F + Sbjct: 243 NDGIDRTTPFVPYQ--VNDEVMAKANDGAIFLHCLPAYRGKEVAASVIDGPASKVFDEAE 300 Query: 288 NGVPVRMAVI 297 N + + A++ Sbjct: 301 NRLHAQKALL 310 >PA3537 [E] COG0078 Ornithine carbamoyltransferase Length = 305 Score = 80.5 bits (197), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 78/307 (25%), Positives = 138/307 (44%), Gaps = 32/307 (10%) Query: 10 RSLLGIKELDRTEILQLLNRTAYWDNQAEK--LTPVLRSHFVANMFFENSTRTRFSFEMA 67 R L + E++ L+ R + + + L L+S + +F + STRTR SFE Sbjct: 4 RHFLSFMDYSPEELIGLIRRGSELKDLRNRGVLYEPLKSRVLGMVFEKASTRTRLSFEAG 63 Query: 68 EKRLGVQVLNFTAAASSVEKGESIYDTVRTLESMGIDAGVVRLKPAGVLQQLAEKVSIPL 127 +LG Q + + + + +GE I D+ R + M +D ++R L + A +P+ Sbjct: 64 MIQLGGQAIFLSPRDTQLGRGEPIGDSARVMSRM-LDGVMIRTFAHATLTEFAAHSKVPV 122 Query: 128 INAGDGNNEHPTQALLDLYTMSKNFGELKGLKVSIIGDIMHSRVARSNLWGLTKMGAKVQ 187 IN G ++ HP Q L D+ T ++ G ++G V+ IGD + + S + K +++ Sbjct: 123 IN-GLSDDLHPCQLLADMQTFHEHRGSIQGKTVAWIGD--GNNMCNSYIEAALKFDFQLR 179 Query: 188 FCAPDNMKAPELAEFAPYVTMEEALKADVVMMLRVQLERHATGILQSADEYRKQFGLTEE 247 P+ + AEF AL D + ++R E A L S D + G +E Sbjct: 180 VACPEGYEPK--AEFV-------ALAGDRLRVVRDPREAVAGAHLVSTDVW-ASMGQEDE 229 Query: 248 RAAK-------------LD---KNTIIMHPAPVNRNVEIDDAVVESDKSRIFPQMANGVP 291 AA+ LD + + MH P +R EI + +++ +S + Q N + Sbjct: 230 AAARIALFRPYQVNAALLDGAADDVLFMHCLPAHRGEEISEELLDDPRSVAWDQAENRLH 289 Query: 292 VRMAVIE 298 + A++E Sbjct: 290 AQKALLE 296 >SMc02137 [E] COG0078 Ornithine carbamoyltransferase Length = 303 Score = 72.8 bits (177), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 64/268 (23%), Positives = 122/268 (45%), Gaps = 24/268 (8%) Query: 44 LRSHFVANMFFENSTRTRFSFEMAEKRLGVQVLNFTAAASSVEKGESIYDTVRTLESMGI 103 L +A +F + STRTR SF++ ++LG + L + + + E+I DT + L S + Sbjct: 39 LAGKMLAMIFEKPSTRTRVSFDVGMRQLGGETLFLSGTEMQLGRAETIGDTAKVL-SRYV 97 Query: 104 DAGVVRLKPAGVLQQLAEKVSIPLINAGDGNNEHPTQALLDLYTMSKNFGELKGLKVSII 163 DA ++R L ++AE ++P+IN G ++ HP Q + D+ T ++ G +KG ++ Sbjct: 98 DAIMIRTTDHRRLLEMAEHATVPVIN-GLTDDTHPCQIMADILTFEEHRGPVKGKTIAWT 156 Query: 164 GD---IMHSRVARSNLWGLTKMGAKVQFCAPDNMKAPELA-----------EFAPYVTME 209 GD ++HS + S +G +M V + + K A E V Sbjct: 157 GDGNNVLHSLIEGSARFGY-RMNMAVPLGSEPHDKFLNWARNNGAEVLLSHEAEQAVAGA 215 Query: 210 EALKADVVMMLRVQLERHATGILQSADEYRKQFGLTEERAAKLDKNTIIMHPAPVNRNVE 269 + D + + + + Q Y+ L + A + + MH P +R E Sbjct: 216 HCVVTDTWISMNQEHRARGHNVFQP---YQVNGALMKHAA----PDALFMHCLPAHRGEE 268 Query: 270 IDDAVVESDKSRIFPQMANGVPVRMAVI 297 + D V++ +S +F + N + + +++ Sbjct: 269 VTDEVIDGPQSVVFDEAENRLHAQKSIL 296 >L0109 [E] COG0078 Ornithine carbamoyltransferase Length = 354 Score = 70.1 bits (170), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 60/187 (32%), Positives = 90/187 (48%), Gaps = 5/187 (2%) Query: 10 RSLLGIKELDRTEILQLLNRTAYWDNQAEKLTP--VLRSHFVANMFFENSTRTRFSFEMA 67 RSLL K+ EI L++ + ++ P L +A +F + STRTR +F A Sbjct: 18 RSLLAEKDFTPAEINYLVDFGLHLKALKQQNIPHHYLEGKNIALLFAKTSTRTRAAFTTA 77 Query: 68 EKRLGVQVLNFTAAASSVEKGESIYDTVRTLESMGIDAGVVRLKPAGVLQQLAEKVSIPL 127 LG A + ES DT R L SM DA R ++ LA+ +P+ Sbjct: 78 AIDLGAHPEYLGANDIQLGIKESTEDTARVLGSM-FDAIERRGFSQKEVEDLAKYSGVPV 136 Query: 128 INAGDGNNEHPTQALLDLYTMSKNFGELKGLKVSIIGDIMHSRVARSNLWGLTKMGAKVQ 187 N G ++ HPTQ + D T+ +NFG LKGL + +GD + +A S + + +G V Sbjct: 137 WN-GLTDDWHPTQMIADFMTVKENFGHLKGLTLVYVGD-GRNNMANSLIVTGSMLGVNVH 194 Query: 188 FCAPDNM 194 APD++ Sbjct: 195 IVAPDSL 201 >ML0109 [C] COG0277 FAD/FMN-containing dehydrogenases Length = 354 Score = 70.1 bits (170), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 60/187 (32%), Positives = 90/187 (48%), Gaps = 5/187 (2%) Query: 10 RSLLGIKELDRTEILQLLNRTAYWDNQAEKLTP--VLRSHFVANMFFENSTRTRFSFEMA 67 RSLL K+ EI L++ + ++ P L +A +F + STRTR +F A Sbjct: 18 RSLLAEKDFTPAEINYLVDFGLHLKALKQQNIPHHYLEGKNIALLFAKTSTRTRAAFTTA 77 Query: 68 EKRLGVQVLNFTAAASSVEKGESIYDTVRTLESMGIDAGVVRLKPAGVLQQLAEKVSIPL 127 LG A + ES DT R L SM DA R ++ LA+ +P+ Sbjct: 78 AIDLGAHPEYLGANDIQLGIKESTEDTARVLGSM-FDAIERRGFSQKEVEDLAKYSGVPV 136 Query: 128 INAGDGNNEHPTQALLDLYTMSKNFGELKGLKVSIIGDIMHSRVARSNLWGLTKMGAKVQ 187 N G ++ HPTQ + D T+ +NFG LKGL + +GD + +A S + + +G V Sbjct: 137 WN-GLTDDWHPTQMIADFMTVKENFGHLKGLTLVYVGD-GRNNMANSLIVTGSMLGVNVH 194 Query: 188 FCAPDNM 194 APD++ Sbjct: 195 IVAPDSL 201 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.132 0.366 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 20,108,632 Number of extensions: 740872 Number of successful extensions: 1577 Number of sequences better than 1.0e-05: 24 Number of HSP's gapped: 1574 Number of HSP's successfully gapped: 24 Length of query: 302 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 196 Effective length of database: 26,153,027 Effective search space: 5125993292 Effective search space used: 5125993292 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 115 (48.9 bits)