BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0263.0015.p
         (396 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

all1641 [GEPR] COG0477 Permeases of the major facilitator superf...   192   7e-49
BH0884 [GEPR] COG0477 Permeases of the major facilitator superfa...    79   1e-14

>all1641 [GEPR] COG0477 Permeases of the major facilitator superfamily
          Length = 388

 Score =  192 bits (488), Expect = 7e-49,   Method: Compositional matrix adjust.
 Identities = 118/357 (33%), Positives = 195/357 (54%), Gaps = 2/357 (0%)

Query: 6   THKTGKLGDLFGGGKAVIYGIALLVGTSVGVINPLSTTHMTANHGEEIWIGVISSSYFFF 65
           T+KT  +   F  G   +Y +A L G S+G+ NP  +T M  N+  +I IG  S+ YFF 
Sbjct: 2   TNKT--IDSPFAPGLPALYIVAFLSGISLGLFNPFISTLMKQNNINDIVIGANSTLYFFI 59

Query: 66  MALGSMAADRTMRGTDMKRVITSGLLLTAVCSALFPLFTVNAVWLLLMSLMGIGISCNMM 125
           +A+G+    + +R   +++ +  G LL  + + LFP  T  + W L+ ++MG+     ++
Sbjct: 60  IAIGTPLVTKILRQIGLRKTMMLGFLLMGITAPLFPFTTQLSAWFLIRAVMGLACCLYLI 119

Query: 126 GLQTALHSLTGEKSLGMVSGMYSLCFALGLIASSALAPMVYDQVAWLPFAFSSFCLVLAS 185
             QTA++    +K+ G+V+G+ +LCF+LG      +    Y+      F   S  ++   
Sbjct: 120 SGQTAINYFCNDKNRGIVNGLDALCFSLGFGIGPVMGAAFYNASPKTTFLLGSGLILSGI 179

Query: 186 AVIYFKLPGTLVIPGHAGKKVLSKINLPLFGAFVYGFGETIVVALYPLYLIREHVAVAQT 245
            V+Y  LP   +       +++ K+ LPL G+F YGF    +V+LYPLYL+ ++  V + 
Sbjct: 180 IVVYLGLPEKEIKFQIPRFQIIKKLRLPLHGSFAYGFSVATLVSLYPLYLLEQNYGVERI 239

Query: 246 GYGLSIFAVGSILGLLPVTYLADRIGCKRCLILCVAISIFTLLGIVNSGSMPLRLLFSFA 305
           GY   +F +G ++  +PVT+LADRIG  + L   V + I +++G+       +   F+F 
Sbjct: 240 GYIFGLFILGGLISTIPVTHLADRIGKVKALRCSVIVVIVSVIGLSFIDDPNITPFFAFI 299

Query: 306 SGFIIGPLYPLAMALTAQVLTPAERSSGNALFTTFYGFGSAAGPFLSSVAMNAWGNQ 362
           SG  + P++PL++AL    L   E SSG+ALFT+ Y  G  AGP LS++ M   G Q
Sbjct: 300 SGVGMSPVFPLSLALIGSRLAVDELSSGSALFTSIYSAGCTAGPILSAIVMTLLGTQ 356


>BH0884 [GEPR] COG0477 Permeases of the major facilitator superfamily
          Length = 401

 Score = 79.3 bits (194), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 80/303 (26%), Positives = 131/303 (43%), Gaps = 17/303 (5%)

Query: 68  LGSMAADRTMRGTDMKRVITSGLLLTAVCSALFPLFTVNAVWLLLMSLMGIGISCNMMGL 127
           L S   ++ +R    K +IT GL+   V   + PL+     W +L  ++GI  +      
Sbjct: 62  LASPFIEKPLRRYGYKPIITIGLMAMIVSLLVLPLWQAFWFWFVLRMIIGIADNMVHFAT 121

Query: 128 QTALHSLTGEKSLGMVSGMYSLCFALGLIASSALAPMVYDQV---AWLPF---AFSSFCL 181
           Q  + + +  K  G     Y   F LG      L P +   +    +LPF   A +SF  
Sbjct: 122 QVWITTTSPMKKRGRNISFYGFAFGLGF----GLGPFMTRLLQINEFLPFILSAITSFAA 177

Query: 182 VLASAVIYFKLPGTLVIPGHAG------KKVLSKINLPLFGAFVYGFGETIVVALYPLYL 235
            L    +  + P   V  G         K V+      L  AF YG+ E+ +   +P+Y 
Sbjct: 178 WLLILRLRNEYPAQDVETGSQSGTWTRYKAVVKLGWFALLPAFCYGYLESSLHGNFPVYG 237

Query: 236 IREHVAVAQTGYGLSIFAVGSILGLLPVTYLADRIGCKRCLILCVAISIFTLLGIVNSGS 295
           +R  + V Q    L  F VG ++  +P+ +L+DR+G K  L++ +     T + +V    
Sbjct: 238 LRSGLTVEQVSILLPAFVVGGLITQMPLGFLSDRMGRKPLLLMVLFFGGATFMSMVYLEH 297

Query: 296 MPLRLLFSFA-SGFIIGPLYPLAMALTAQVLTPAERSSGNALFTTFYGFGSAAGPFLSSV 354
             + L  SFA +G  +G LY L +   A +L P    +GN +    +G GS  GP +  V
Sbjct: 298 TFIGLFLSFALAGAFVGSLYSLGVMYMADLLPPHLLPTGNVMMAVSFGLGSMIGPMVGGV 357

Query: 355 AMN 357
            ++
Sbjct: 358 FID 360


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.326    0.140    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 26,316,662
Number of extensions: 1070177
Number of successful extensions: 4599
Number of sequences better than 1.0e-05: 7
Number of HSP's gapped: 4610
Number of HSP's successfully gapped: 7
Length of query: 396
Length of database: 38,378,431
Length adjustment: 108
Effective length of query: 288
Effective length of database: 25,922,359
Effective search space: 7465639392
Effective search space used: 7465639392
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 117 (49.7 bits)