BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0260.0031.p (178 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_ywhH [S] COG2606 Uncharacterized conserved protein 224 4e-59 SMc02318 [S] COG2606 Uncharacterized conserved protein 149 3e-36 STM4549 [S] COG2606 Uncharacterized conserved protein 144 8e-35 PA1357 [S] COG2606 Uncharacterized conserved protein 141 4e-34 FN0673 [S] COG2606 Uncharacterized conserved protein 140 1e-33 >BS_ywhH [S] COG2606 Uncharacterized conserved protein Length = 157 Score = 224 bits (572), Expect = 4e-59, Method: Compositional matrix adjust. Identities = 107/156 (68%), Positives = 126/156 (80%) Query: 11 LSIANVKEHFRRVGREQDILEFATSSATVEMAAATIGVIPARIAKTLSFRGTDESAILVV 70 +S+ +V+ HF + RE D+ EF TSSATVE AA TIGV +RIAK+LSFRG + IL+V Sbjct: 1 MSLKSVRTHFTQWNRENDVTEFETSSATVEQAAETIGVSLSRIAKSLSFRGEGDQVILIV 60 Query: 71 AAGDAKVDNKKFRESFGLKARMLSPEEVLEQTGHEIGGVCPFGLARDLEVYLDVSMKRFT 130 AAGDAK+DNKK R++FG KARMLSP EVLEQTGHEIGGVCPFGLA D EVYLDVS+KRF Sbjct: 61 AAGDAKIDNKKSRQTFGFKARMLSPNEVLEQTGHEIGGVCPFGLAHDPEVYLDVSLKRFQ 120 Query: 131 TLFPACGSTNSAIELNCDELAVYSGAKDWVDVCKGW 166 T+FPACGS NSAIEL EL+ +S +K W+DVCK W Sbjct: 121 TVFPACGSRNSAIELTPKELSEFSFSKVWIDVCKDW 156 >SMc02318 [S] COG2606 Uncharacterized conserved protein Length = 153 Score = 149 bits (375), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 76/152 (50%), Positives = 107/152 (70%), Gaps = 2/152 (1%) Query: 11 LSIANVKEHFRRVGREQDILEFATSSATVEMAAATIGVIPARIAKTLSFRGTDESAILVV 70 +S+A+VK+ F R + D++E S+ATV +AA GV PA+IAKTL+ R DE IL+V Sbjct: 1 MSLASVKQFFSRHAPDIDVIELEQSTATVALAAEGHGVEPAQIAKTLALRVGDE-IILIV 59 Query: 71 AAGDAKVDNKKFRESFGLKARMLSPEEVLEQTGHEIGGVCPFGLARDLEVYLDVSMKRFT 130 GDA++DNKK++ FG KARML +EV +TGH +GGVCPFGLA+ VY D S+K F Sbjct: 60 TRGDARLDNKKYKARFGTKARMLGFDEVEAETGHPVGGVCPFGLAKPHSVYCDESLKSFD 119 Query: 131 TLFPACGSTNSAIELNCDELAVYSGAKDWVDV 162 + PA G+TN+A+ ++ + +A +GAK W+DV Sbjct: 120 IVVPAAGATNAAVHISPERMAELTGAK-WIDV 150 >STM4549 [S] COG2606 Uncharacterized conserved protein Length = 152 Score = 144 bits (362), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 72/154 (46%), Positives = 104/154 (67%), Gaps = 2/154 (1%) Query: 11 LSIANVKEHFRRVGREQDILEFATSSATVEMAAATIGVIPARIAKTLSFRGTDESAILVV 70 +S+ +V++ + +I+E S+ATVE+AA V P +IAKTLS + D + ILVV Sbjct: 1 MSLQSVRQFLADHAPDIEIIELNQSTATVELAAKAHNVEPGQIAKTLSLKVKD-TIILVV 59 Query: 71 AAGDAKVDNKKFRESFGLKARMLSPEEVLEQTGHEIGGVCPFGLARDLEVYLDVSMKRFT 130 A GDA++DNKK + +FG KARMLS +EV+ TGH +GGVCPFGL L VY D+S+K + Sbjct: 60 AKGDARLDNKKLKTTFGAKARMLSSDEVVNATGHPVGGVCPFGLEHPLPVYCDISLKGYN 119 Query: 131 TLFPACGSTNSAIELNCDELAVYSGAKDWVDVCK 164 + PA G+T+SA+ + + +A + A WVDVC+ Sbjct: 120 EVLPAAGATHSAVRITPERMAELTSAT-WVDVCQ 152 >PA1357 [S] COG2606 Uncharacterized conserved protein Length = 158 Score = 141 bits (356), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 74/154 (48%), Positives = 102/154 (66%), Gaps = 2/154 (1%) Query: 11 LSIANVKEHFRRVGREQDILEFATSSATVEMAAATIGVIPARIAKTLSFRGTDESAILVV 70 +S+ +V+ F + I+E TS+ATV +AA GV P RIAKTLS R E +LVV Sbjct: 1 MSLESVRRFFAEKAPDLRIIELETSTATVALAAEAHGVEPGRIAKTLSLR-VGERTVLVV 59 Query: 71 AAGDAKVDNKKFRESFGLKARMLSPEEVLEQTGHEIGGVCPFGLARDLEVYLDVSMKRFT 130 A GDA++DN+K + +FG KA+ML E+V+E TGH +GGVCPFGLA L VY DVS++ F Sbjct: 60 ARGDARLDNRKIKAAFGGKAKMLGAEDVVELTGHPVGGVCPFGLATPLAVYCDVSLQAFD 119 Query: 131 TLFPACGSTNSAIELNCDELAVYSGAKDWVDVCK 164 + PA G+ +SA+ + +A A+ WVDVC+ Sbjct: 120 EVLPAAGAVHSAVRIAPQRMAELVDAQ-WVDVCQ 152 >FN0673 [S] COG2606 Uncharacterized conserved protein Length = 154 Score = 140 bits (353), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 77/154 (50%), Positives = 104/154 (67%), Gaps = 1/154 (0%) Query: 11 LSIANVKEHFRRVGREQDILEFATSSATVEMAAATIGVIPARIAKTLSFRGTDESAILVV 70 +SI ++H + G + I EF S+ATVE AA PARIAK+LSF D AI+VV Sbjct: 1 MSIEAARKHLEKYGLDNKIREFKESTATVEKAAKVNSCEPARIAKSLSFIINDIPAIIVV 60 Query: 71 AAGDAKVDNKKFRESFGLKARMLSPEEVLEQTGHEIGGVCPFGLARDLEVYLDVSMKRFT 130 A GDAK++N+KF+ F KA+M++ +V GH +GGVCPFG+ +++VYLD SMKRF Sbjct: 61 A-GDAKINNQKFKAKFKTKAKMIAGNDVENLIGHPVGGVCPFGIKDNVKVYLDESMKRFE 119 Query: 131 TLFPACGSTNSAIELNCDELAVYSGAKDWVDVCK 164 T+ PACG+ NSAIEL +EL S +W+DVC+ Sbjct: 120 TMLPACGTANSAIELTLEELEKASNYIEWIDVCQ 153 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.133 0.385 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 12,226,413 Number of extensions: 472846 Number of successful extensions: 6962 Number of sequences better than 1.0e-05: 21 Number of HSP's gapped: 6955 Number of HSP's successfully gapped: 21 Length of query: 178 Length of database: 38,378,431 Length adjustment: 99 Effective length of query: 79 Effective length of database: 26,960,365 Effective search space: 2129868835 Effective search space used: 2129868835 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 112 (47.8 bits)