BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0258.0001.p (669 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value all4225_2 [T] COG2200 FOG: EAL domain 218 4e-56 RSc0510_3 [T] COG2200 FOG: EAL domain 213 7e-55 alr1230_2 [T] COG2200 FOG: EAL domain 211 2e-54 PA1727_3 [T] COG2200 FOG: EAL domain 210 8e-54 all1175_4 [T] COG2200 FOG: EAL domain 209 1e-53 >all4225_2 [T] COG2200 FOG: EAL domain Length = 260 Score = 218 bits (554), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 108/247 (43%), Positives = 153/247 (61%), Gaps = 1/247 (0%) Query: 415 RMSLEKDLRKALARSEFMVVYQPKWDSLMNVTVGLEALLRWRHPEHGIISPAEFIPIAEE 474 R++LE +L AL R+E +V YQP D +EAL+RW+HP G++SPA+FIPIAE Sbjct: 2 RLALENELHGALERNEIVVYYQPIIDLQTKQITAVEALVRWQHPTRGLVSPAKFIPIAEA 61 Query: 475 TGLIVPITYWMLHDVCGQNKLWHKACVANVAVSINMSARMFEGGSLYDVVEEALVRSGLE 534 GLIV I W+L C QN+ W A + + +S+N+SAR FE +L ++V E + SGL Sbjct: 62 NGLIVEIGEWVLRTACLQNRTWQLAGLPPIRMSVNLSARQFEESNLVELVSEIIQESGLH 121 Query: 535 PHFLELEITESIAMNNMEETVAQLSKLRNLGVRVSLDDFGTGFSSLGNLDEIPVNTLKID 594 P +LELE+TES M +++ +V L +LR LGV ++LDDFGTG+SSL L PVN LKID Sbjct: 122 PSYLELEVTESSLMTDIQRSVTILKQLRELGVWLALDDFGTGYSSLNYLKRFPVNMLKID 181 Query: 595 QVFIRK-SKMHXXXXXXXXXXXXXXXLNMEVVAEGVETPEQIELLQSLGCRVMQGFYYGR 653 + F++ L +++ AEG+ET +Q+ LQ GC+ QG+Y+G Sbjct: 182 RSFVQDVCSNPDSAAVTNAIIALAKSLQLKITAEGIETQQQLSYLQKRGCQEGQGYYFGI 241 Query: 654 PMPVSEL 660 P P E+ Sbjct: 242 PAPAKEI 248 >RSc0510_3 [T] COG2200 FOG: EAL domain Length = 282 Score = 213 bits (543), Expect = 7e-55, Method: Compositional matrix adjust. Identities = 108/256 (42%), Positives = 154/256 (60%), Gaps = 1/256 (0%) Query: 401 FSVFDQEMNRHQLRRMSLEKDLRKALARSEFMVVYQPKWDSLMNVTVGLEALLRWRHPEH 460 + F+ MN + +++ L +DLR AL R E ++ YQPK+ + VG+EAL+RW+HPE Sbjct: 1 YCFFEASMNTNVHQQLQLVQDLRLALERHELVLHYQPKFSAPHGPVVGVEALVRWQHPER 60 Query: 461 GIISPAEFIPIAEETGLIVPITYWMLHDVCGQNKLWHKACVANVAVSINMSARMFEGGSL 520 G++ P FIP+AE+TGLIVP+ W+L + C Q W + A ++++N+SA F +L Sbjct: 61 GLVQPDAFIPLAEKTGLIVPLGAWVLDEACRQMAQWRREGHAQWSIAVNLSAVQFAHAAL 120 Query: 521 YDVVEEALVRSGLEPHFLELEITESIAMNNMEETVAQLSKLRNLGVRVSLDDFGTGFSSL 580 D V + L R LEP L LEITES AM + + ++ L +L +GVR+S+DDFGTG+SSL Sbjct: 121 VDTVRDTLARHALEPQGLTLEITESTAMRDADASLHILQQLHAMGVRISIDDFGTGYSSL 180 Query: 581 GNLDEIPVNTLKIDQVFIRK-SKMHXXXXXXXXXXXXXXXLNMEVVAEGVETPEQIELLQ 639 L +P + LKID+ F+R + LN+ +VAEGVET Q L Sbjct: 181 LYLKRLPASELKIDRGFVRDLAHDSEDAAIVSAVVALGQTLNLRIVAEGVETEAQQAFLT 240 Query: 640 SLGCRVMQGFYYGRPM 655 LGC +QG GRPM Sbjct: 241 RLGCHALQGNLLGRPM 256 >alr1230_2 [T] COG2200 FOG: EAL domain Length = 266 Score = 211 bits (538), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 110/259 (42%), Positives = 156/259 (60%), Gaps = 2/259 (0%) Query: 410 RHQLRRMSLEKDLRKALARSEFMVVYQPKWDSLMNVTVGLEALLRWRHPEHGIISPAEFI 469 + QL MSL K +++ EF V YQP D V E+LLRW PE G +SP+EFI Sbjct: 4 KTQLLEMSLHKVIQQQ-KFPEFEVQYQPIVDIASGKIVAAESLLRWNSPELGFVSPSEFI 62 Query: 470 PIAEETGLIVPITYWMLHDVCGQNKLWHKACVANVAVSINMSARMFEGGSLYDVVEEALV 529 P+AE TGLIVPI W++ +VC Q K WH + V + +S+N+SA F L + EAL Sbjct: 63 PLAESTGLIVPIGQWVIANVCHQIKSWHDSGVDFLTISVNLSAMEFNKPDLIQRITEALK 122 Query: 530 RSGLEPHFLELEITESIAMNNMEETVAQLSKLRNLGVRVSLDDFGTGFSSLGNLDEIPVN 589 + + PH+LE+E+TES+ M ++ + +++L++LGVR+++DDFGTG+SSL L +PVN Sbjct: 123 SNNIAPHYLEIELTESMIMQDLNSAIFTMNELQSLGVRLAIDDFGTGYSSLIYLKNLPVN 182 Query: 590 TLKIDQVFIRK-SKMHXXXXXXXXXXXXXXXLNMEVVAEGVETPEQIELLQSLGCRVMQG 648 TLKID+ FI +K +NM+VVAEGVET ++ L+ C MQG Sbjct: 183 TLKIDRYFIHNVAKDKQKSAITKALIEMAHNMNMQVVAEGVETESELYFLKQNKCDAMQG 242 Query: 649 FYYGRPMPVSELGQWFIEN 667 F + RP+P E + N Sbjct: 243 FLFSRPLPAVEFENFLWNN 261 >PA1727_3 [T] COG2200 FOG: EAL domain Length = 254 Score = 210 bits (534), Expect = 8e-54, Method: Compositional matrix adjust. Identities = 108/247 (43%), Positives = 153/247 (61%), Gaps = 1/247 (0%) Query: 415 RMSLEKDLRKALARSEFMVVYQPKWDSLMNVTVGLEALLRWRHPEHGIISPAEFIPIAEE 474 ++ L DLR+AL R + ++ YQPK + +G+EALLRW HP+HG+I+P +F+P+AE+ Sbjct: 3 QLQLLHDLRQALERRQLVLHYQPKVLAPNGPMIGVEALLRWEHPQHGLITPGQFLPLAEK 62 Query: 475 TGLIVPITYWMLHDVCGQNKLWHKACVANVAVSINMSARMFEGGSLYDVVEEALVRSGLE 534 TGLIV I W+L + C Q +LW A+ +++N+SA F L D V AL+R LE Sbjct: 63 TGLIVQIGEWVLDEACRQMRLWLDGGHADWNIAVNLSALQFAHAGLVDSVRNALLRHSLE 122 Query: 535 PHFLELEITESIAMNNMEETVAQLSKLRNLGVRVSLDDFGTGFSSLGNLDEIPVNTLKID 594 P L LE+TES AM + + ++ L +L +GV +S+DDFGTG+SSL L +P + LKID Sbjct: 123 PSHLILEVTESTAMRDADASLVILEQLSAMGVGISIDDFGTGYSSLLYLKRLPASELKID 182 Query: 595 QVFIRK-SKMHXXXXXXXXXXXXXXXLNMEVVAEGVETPEQIELLQSLGCRVMQGFYYGR 653 + FI + + LN+++VAEGVET Q E L LGC +QGF GR Sbjct: 183 RGFINELAHDSDDAAIVSAIVALGRTLNLKIVAEGVETEAQQEFLTRLGCNSLQGFLLGR 242 Query: 654 PMPVSEL 660 PMP +L Sbjct: 243 PMPAEQL 249 >all1175_4 [T] COG2200 FOG: EAL domain Length = 261 Score = 209 bits (531), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 102/241 (42%), Positives = 153/241 (63%), Gaps = 1/241 (0%) Query: 416 MSLEKDLRKALARSEFMVVYQPKWDSLMNVTVGLEALLRWRHPEHGIISPAEFIPIAEET 475 ++LEK LR AL + E V YQP+ + L G+EALLRW+HPE GI++P+ FIPIAEET Sbjct: 3 LTLEKSLRYALEKQELKVYYQPRVNILTGQITGMEALLRWQHPEMGIVAPSIFIPIAEET 62 Query: 476 GLIVPITYWMLHDVCGQNKLWHKACVANVAVSINMSARMFEGGSLYDVVEEALVRSGLEP 535 GLI+PI W+L C QN+ W +A + V +++N+S + F +L ++V L +GL P Sbjct: 63 GLIIPIGEWVLRTACMQNRAWQEAGLPPVQMAVNLSPKQFRQPTLLELVSAILAETGLAP 122 Query: 536 HFLELEITESIAMNNMEETVAQLSKLRNLGVRVSLDDFGTGFSSLGNLDEIPVNTLKIDQ 595 FLELEITES A+ +++ T + L L+ +GV +++DDFGTG SSL L +P++ LKID Sbjct: 123 EFLELEITESTAIEDIDFTRSVLENLQQMGVDIAIDDFGTGHSSLSRLQLLPLHNLKIDG 182 Query: 596 VFIRK-SKMHXXXXXXXXXXXXXXXLNMEVVAEGVETPEQIELLQSLGCRVMQGFYYGRP 654 FI+ + L + + AEGVE E+++ L+S+ C+ +QGF + +P Sbjct: 183 SFIKALTTDSKVAHIVKAIVTLGRSLGLRLTAEGVEKQEELDFLKSINCQDVQGFLFHKP 242 Query: 655 M 655 + Sbjct: 243 L 243 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.324 0.138 0.421 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 43,496,461 Number of extensions: 1689469 Number of successful extensions: 6109 Number of sequences better than 1.0e-05: 267 Number of HSP's gapped: 5684 Number of HSP's successfully gapped: 268 Length of query: 669 Length of database: 38,378,431 Length adjustment: 113 Effective length of query: 556 Effective length of database: 25,345,689 Effective search space: 14092203084 Effective search space used: 14092203084 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.5 bits) S2: 119 (50.4 bits)