BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0256.0033.p
         (368 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

alr1924 [E] COG0337 3-dehydroquinate synthetase                       239   5e-63
all0417 [E] COG0337 3-dehydroquinate synthetase                        91   2e-18

>alr1924 [E] COG0337 3-dehydroquinate synthetase
          Length = 346

 Score =  239 bits (610), Expect = 5e-63,   Method: Compositional matrix adjust.
 Identities = 0/366 (0%), Positives = 0/366 (0%), Gaps = 8/366 (2%)

Query: 1   MMRSITVELGERSYPIHIGSGLLRDIGQHCVKAGFPLRSPLLIVSDSEVAPRYLPVVEAA 60
           M              + +G+    +                +    + +    +  V   
Sbjct: 1   MQYHRIPHSSLEVSTLGLGTMTFGEQNSEA--DAHAQLDYAVAQGINLIDVAEMYPVPPR 58

Query: 61  LRGEGYAVVSHVIPAGEASKSLAVYEEVITTAIQAGLDRSSXXXXXXXXXXXXXXXXXXX 120
              +G           +      +      +      D+                     
Sbjct: 59  PETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSL 118

Query: 121 TFMRGIGFIQIPTTILAH-DSSVGGKVAVNHPLAKNMIGAFYQPSLVLYDLDTLSTLPPR 179
             ++                +  G         A  +       +L  Y           
Sbjct: 119 KRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGV 178

Query: 180 QISSGLAEVVKHGLILDRDFAYWCLEHASELLSL---NTEALGYALERGCAIKAQVVSND 236
              +    +    L    D     +   +    L       L    +             
Sbjct: 179 SNETAFGVMRYLHLADKHDL-PRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLG 237

Query: 237 EREHGQRAFLNLGHTIGHAIEAVGGYGVFLHGEAIAIGMAGSALLAAKLG-RERAIYEDT 295
                 +                            A+           L   + A+    
Sbjct: 238 FGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVR 297

Query: 296 IAMLSALSLPVKLPAEYSEDELMEAMMHDKKFKEGKMTFIVPDSIGAVSIVNDVQPSAVR 355
                                                                       
Sbjct: 298                                                              357

Query: 356 EVLAQL 361
                 
Sbjct: 358        363


>all0417 [E] COG0337 3-dehydroquinate synthetase
          Length = 346

 Score = 91.3 bits (225), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 0/299 (0%), Positives = 0/299 (0%), Gaps = 5/299 (1%)

Query: 72  VIPAGEASKSLAVYEEVITTAIQA-GLDRSSXXXXXXXXXXXXXXXXXXXTFMRGIGFIQ 130
                   ++L               L                        +        
Sbjct: 95  NDKGIRPDQALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPA 154

Query: 131 IPTTILA-HDSSVGGKVAVNHPLAKNMIGAFYQPSLVLYDLDTLSTLPPRQISSGLAEVV 189
           +         +       + +    N         L L D   L  +   Q    L    
Sbjct: 155 VSLLDTLDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRS 214

Query: 190 KHGLILDRDFAYWCLEHASELLSLNTEALGYALERGCAIKAQ-VVSNDEREHGQRAFLNL 248
               + +          A   L   T    Y      A     + S   R  G++    +
Sbjct: 215 FEVGLAEVSQYEGVELLAYSCLGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAV 274

Query: 249 GHTIGHAIEAVGGYGVFLHGEAIAIGMAGSALLAAKLGR-ERAIYEDTIAMLSALSLPVK 307
              +  A          +    +      ++ L       +     +++ +  +  +  +
Sbjct: 275 AAYVDIARRHGLDPAQ-MALAFVRRQPFVASTLLGATTMDQLKTNIESLHLELSEDVLAE 333

Query: 308 LPAEYSEDELMEAMMHDKKFKEGKMTFIVPDSIGAVSIVNDVQPSAVREVLAQLKKEGS 366
                                                                      
Sbjct: 334                                                             392


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.319    0.136    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 24,606,056
Number of extensions: 969739
Number of successful extensions: 2566
Number of sequences better than 1.0e-05: 2
Number of HSP's gapped: 2559
Number of HSP's successfully gapped: 2
Length of query: 368
Length of database: 38,378,431
Length adjustment: 108
Effective length of query: 260
Effective length of database: 25,922,359
Effective search space: 6739813340
Effective search space used: 6739813340
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 116 (49.3 bits)