BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0256.0030.p (362 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGc3100 [E] COG0547 Anthranilate phosphoribosyltransferase 253 3e-67 PA0650 [E] COG0547 Anthranilate phosphoribosyltransferase 251 1e-66 ML0052 [D] COG1674 DNA segregation ATPase FtsK/SpoIIIE and relat... 242 6e-64 RSp0681 [E] COG0547 Anthranilate phosphoribosyltransferase 240 2e-63 RSc2884 [E] COG0547 Anthranilate phosphoribosyltransferase 239 4e-63 >AGc3100 [E] COG0547 Anthranilate phosphoribosyltransferase Length = 301 Score = 253 bits (646), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 0/331 (0%), Positives = 0/331 (0%), Gaps = 2/331 (0%) Query: 27 IASIIEGRDLSRLQAREIMGSIMEGSASAAQIGSLLTALRIKGETVEEITGFAEAMRGFS 86 I + ++ + + + + ++ + T G Sbjct: 8 CGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGAYQAIYVDTPGLH 67 Query: 87 THVATERSQLLDTCGTGGSGIHKFNXXXXXXXXXXXXXVRVAKHGNRSASGRAGSADVLE 146 L S + + R A Sbjct: 68 MEEKRA-INRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLREGKAPVILAVNKV 126 Query: 147 ALGVNIHLNAEQARQCLDSIGICFLFAQIYHPSMKHAAAPRKELGFRTVFNMLGPLTNPA 206 + + + + P Sbjct: 127 DNVQEKADLLPHLQFLASQMNFLDIVPISAETGLNVDTIAAIVRKHLPEATHHFPEDYIT 186 Query: 207 GADRQLMGIYDRDKTQTIAHVLKELGSKRAMIVSSLDGLDEISISAPTQVSELKNGMVTT 266 ++ M + + S I + + + G Sbjct: 187 DRSQRFMASEIIREKLMRFLGAELPYSVTVEIERF-VSNERGGYDINGLILVEREGQKKM 245 Query: 267 YEITPQELGLSTHPLENVLGGDAAVNAAIITGVLQGDVNPYRDIVLANAGACIYVAGLAD 326 Sbjct: 246 305 Query: 327 TLQEGVEQAKAVVDSGAALLKLEQLKAMTKE 357 Sbjct: 306 336 >PA0650 [E] COG0547 Anthranilate phosphoribosyltransferase Length = 211 Score = 251 bits (641), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 0/338 (0%), Positives = 0/338 (0%), Gaps = 5/338 (1%) Query: 23 IQSGIASIIEGRDLSRLQAREIMGSIMEGSASAAQIGSLLTALRIKGETVEEITGFAEAM 82 + + R+ + E+ S A + + T + + T + Sbjct: 3 KAKRLEILTRLRENNPHPTTELNFSSPFELLIAVLLSAQATDVSVNKATAKLYPVANTPA 62 Query: 83 RGFSTHVATER-SQLLDTCGTGGSGIHKFNXXXXXXXXXXXXXVRVAKHGNRSASGRAGS 141 V + + A GR + Sbjct: 63 AMLELGVEGVKTYIKTIGLYNSKAENIIKTCRILLEQHNGEVPEDRAALEALPGVGRKTA 122 Query: 142 ADVLEALGVNIHLNAEQARQCLDSIGICFLFAQIYHPSMKHAAAPRKELGFRTVFNMLGP 201 VL + + + + + K E ++ Sbjct: 123 NVVLNTAFGWPTIAVDTHIFRVCNRTQFAPGKNVEQVEEKLLKVVPAEFKVDCHHWLILH 182 Query: 202 LTNPAGADRQLMGIYDRDKTQTIAHVLKELGSKRAMIVSSLDGLDEISISAPTQVSELKN 261 Sbjct: 183 242 Query: 262 GMVTTYEITPQELGLSTHPLENVLGGDAAVNAAIITGVLQGDVN----PYRDIVLANAGA 317 Sbjct: 243 302 Query: 318 CIYVAGLADTLQEGVEQAKAVVDSGAALLKLEQLKAMT 355 Sbjct: 303 340 >ML0052 [D] COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins Length = 342 Score = 242 bits (618), Expect = 6e-64, Method: Compositional matrix adjust. Identities = 131/353 (37%), Positives = 199/353 (56%), Gaps = 15/353 (4%) Query: 1 MNSRSLRWHNEQEETRMDANQRIQSGIASIIEGRDLSRLQAREIMGSIMEGSASAAQIGS 60 M +RS + NE E+ ++ GRD++ + + SI++G S QI S Sbjct: 1 MKTRSHQMKNELEK---------------VMSGRDMTENEMNMLANSIIQGELSEVQIAS 45 Query: 61 LLTALRIKGETVEEITGFAEAMRGFSTHVATERSQLLDTCGTGGSGIHKFNXXXXXXXXX 120 L AL++KGE E+TG A A++ + + T + +D CGTGG FN Sbjct: 46 FLVALKMKGEAASELTGLARALQKAAIPIPTNLTNAMDNCGTGGDRSFSFNISTTAAFVL 105 Query: 121 XXXXVRVAKHGNRSASGRAGSADVLEALGVNIHLNAEQARQCLDSIGICFLFAQIYHPSM 180 V +AKHGNRS + ++GSADVLEALG+N++L AE+ Q D +G+ FLFAQ HP+M Sbjct: 106 AAGGVNMAKHGNRSITSKSGSADVLEALGINLYLPAEKLAQVFDKVGLVFLFAQNLHPAM 165 Query: 181 KHAAAPRKELGFRTVFNMLGPLTNPAGADRQLMGIYDRDKTQTIAHVLKELGSKRAMIVS 240 K+ R++L T+ N+ GPL NP D QL+G D + A+VLK LG KRA++++ Sbjct: 166 KYFTPVRRQLEIPTIMNLTGPLINPIPLDTQLLGTSRPDLLELTANVLKGLGRKRALVIT 225 Query: 241 SLDGLDEISISAPTQVSELKNGMVTTYEITPQELGLSTHPLENVLGGDAAVNAAIITGVL 300 G+DE + + L+N VT +E E+G+S L ++ GG+A NA I+ VL Sbjct: 226 GEGGMDEATPFGLNHYALLENDKVTLHEFRASEVGISEVQLNDIRGGEAPENAEILKNVL 285 Query: 301 QGDVNPYRDIVLANAGACIYVAGLADTLQEGVEQAKAVVDSGAALLKLEQLKA 353 + + + + + NAG Y G D+++ GV+ A+ V+ +GAAL KL +L+A Sbjct: 286 ENQPSAFLETTVLNAGLGFYANGKVDSIKSGVDLAREVISTGAALTKLHELQA 338 >RSp0681 [E] COG0547 Anthranilate phosphoribosyltransferase Length = 344 Score = 240 bits (613), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 135/329 (41%), Positives = 187/329 (56%), Gaps = 1/329 (0%) Query: 23 IQSGIASIIEGRDLSRLQAREIMGSIMEGSASAAQIGSLLTALRIKGETVEEITGFAEAM 82 +++ I + +G+ L R A + + G AS AQ+G+LL ALR++GETVEEI G A AM Sbjct: 4 LKATIGRLAQGQTLGRQDAWMLFEQMAFGHASHAQLGALLMALRVRGETVEEIVGAALAM 63 Query: 83 RGFSTHVATERSQLLDTCGTGGSGIHKFNXXXXXXXXXXXXXVRVAKHGNRSASGRAGSA 142 R V + +D GTGG +N V VAKHGNR+ S ++G+A Sbjct: 64 RARMVPVKAP-ADAVDIVGTGGDNAGTYNISTCAAFIVAGAGVPVAKHGNRALSSKSGAA 122 Query: 143 DVLEALGVNIHLNAEQARQCLDSIGICFLFAQIYHPSMKHAAAPRKELGFRTVFNMLGPL 202 DVL ALGVN+ +C+ GI F+FA +HP++K R +L RT+FN+LGPL Sbjct: 123 DVLSALGVNLDQTPADIERCIAEAGIGFMFAPTHHPALKQLMPVRVDLATRTIFNLLGPL 182 Query: 203 TNPAGADRQLMGIYDRDKTQTIAHVLKELGSKRAMIVSSLDGLDEISISAPTQVSELKNG 262 NPAG L+G+Y R + +AH L +LGS+RA++V DGLDEI+ PT VS L G Sbjct: 183 LNPAGVRHHLIGVYSRAWVEPLAHALGDLGSERALVVHGSDGLDEITTVGPTFVSMLARG 242 Query: 263 MVTTYEITPQELGLSTHPLENVLGGDAAVNAAIITGVLQGDVNPYRDIVLANAGACIYVA 322 V ++EITP+ +GL + G D NA + VL+G YRDI L NA + A Sbjct: 243 RVRSFEITPEMVGLVRANPAELKGADGKWNAVALRRVLEGQPGAYRDIALFNAAGGLIAA 302 Query: 323 GLADTLQEGVEQAKAVVDSGAALLKLEQL 351 G+ + + + A+A VD GAAL L +L Sbjct: 303 GVVENWPDAMALARASVDGGAALATLNRL 331 >RSc2884 [E] COG0547 Anthranilate phosphoribosyltransferase Length = 345 Score = 239 bits (611), Expect = 4e-63, Method: Compositional matrix adjust. Identities = 138/338 (40%), Positives = 195/338 (57%), Gaps = 3/338 (0%) Query: 24 QSGIASIIEGRDLSRLQAREIMGSIMEGSASAAQIGSLLTALRIKGETVEEITGFAEAMR 83 Q + IE R++ + +M IM G S +L+ LR+K ET+ EI A MR Sbjct: 6 QDALTRCIEHREIFHDEMLHLMRLIMRGEMSPVIASALIMGLRVKKETIGEIAAAATVMR 65 Query: 84 GFSTHV---ATERSQLLDTCGTGGSGIHKFNXXXXXXXXXXXXXVRVAKHGNRSASGRAG 140 F+T V A +D GTGG G + FN R+AKHG R S ++G Sbjct: 66 EFATTVDVPAAILDHFVDIVGTGGDGANTFNISTASMFVAAAAGARIAKHGGRGVSSKSG 125 Query: 141 SADVLEALGVNIHLNAEQARQCLDSIGICFLFAQIYHPSMKHAAAPRKELGFRTVFNMLG 200 SADVLEALGVNI L EQ Q ++++GI F+FA +HP+MK+ A RKELG RT+FN+LG Sbjct: 126 SADVLEALGVNIMLTPEQVAQSIEAVGIGFMFAPNHHPAMKNVAPIRKELGVRTLFNILG 185 Query: 201 PLTNPAGADRQLMGIYDRDKTQTIAHVLKELGSKRAMIVSSLDGLDEISISAPTQVSELK 260 PLTNPAGA LMG++ D V++ LG++ A++V DG+DE+S+ A T V ELK Sbjct: 186 PLTNPAGAPNILMGVFHPDLVGIQVRVMQRLGARHAVVVYGKDGMDEVSLGAATVVGELK 245 Query: 261 NGMVTTYEITPQELGLSTHPLENVLGGDAAVNAAIITGVLQGDVNPYRDIVLANAGACIY 320 +G V YEI P++ GL + DA + A++ G L+ R+IV NAGA +Y Sbjct: 246 DGEVREYEIHPEDYGLQMVSNRGLKVADAEESKAMLLGALENVPGTPREIVTLNAGAALY 305 Query: 321 VAGLADTLQEGVEQAKAVVDSGAALLKLEQLKAMTKEL 358 A LA ++ +G+ A+ + SGAA K+++L +T + Sbjct: 306 AANLAGSIGDGITLAREAIASGAARAKVDELVRVTNQF 343 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.316 0.131 0.364 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 23,754,785 Number of extensions: 981058 Number of successful extensions: 2626 Number of sequences better than 1.0e-05: 34 Number of HSP's gapped: 2590 Number of HSP's successfully gapped: 34 Length of query: 362 Length of database: 38,378,431 Length adjustment: 108 Effective length of query: 254 Effective length of database: 25,922,359 Effective search space: 6584279186 Effective search space used: 6584279186 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 116 (49.3 bits)