BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0254.0026.p (314 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value sll0030 [K] COG0583 Transcriptional regulator 126 4e-29 Cgl0015 [K] COG0583 Transcriptional regulator 115 7e-26 sll1594 [K] COG0583 Transcriptional regulator 114 2e-25 all4986 [K] COG0583 Transcriptional regulator 113 5e-25 MJ0300 [K] COG0583 Transcriptional regulator 108 1e-23 >sll0030 [K] COG0583 Transcriptional regulator Length = 304 Score = 126 bits (317), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 89/289 (30%), Positives = 141/289 (48%), Gaps = 7/289 (2%) Query: 19 IHALRLFYYVAETGSVTKAAARLNISQPAVTSQIKKFEKDLGLPLFNPSGRGVSLTPFGI 78 +H +F +A TGS TKAA L ++QP V+ Q+K+ K +G+PL+ GR + LT G Sbjct: 6 LHQFEVFAAIARTGSFTKAAEELFLTQPTVSQQMKQLTKAIGVPLYEQIGRKIYLTEAGQ 65 Query: 79 ELAKQAGNFFTYEEQIDEFVEDYRHGRKGKLRIAATYLPANFLVPGWAARFKAGYPEIEM 138 + + N + +Q+ E + D + +KG LR+ AT + VP F+ YP I + Sbjct: 66 AVLDASKNITSCLDQLQEVIADLQGLKKGNLRL-ATITTGKYFVPRLLGEFRQQYPGISI 124 Query: 139 EITTTNSQQAFEQLKRHEADVAFYGGGAQDRPEDIDWLELFEDELWFVVSPSHPYAG-RT 197 + N QQ E+L + D+ F G + DI+ E+ L + S HP + Sbjct: 125 SLQIGNRQQILERLANNLDDLYFLGKPPSNL--DINIRHFLENPLVVIASRQHPLVKEKK 182 Query: 198 VSLQEMMLEPFIMREEGSSTRARLVSLCVTYGLKPPQVTLQFSGLGEAIR-SVMAGYGAN 256 +SL+ ++ EP IMRE GS TR + LK V ++ S EAI+ +V G G + Sbjct: 183 ISLERLVNEPLIMRESGSGTRMAVEEFFSENRLK-MNVEMEISS-NEAIKQAVYGGLGIS 240 Query: 257 FISSLAVREYVEQKRLSRVQVEGIQLSNHIAICTRSHESVPPALQQFID 305 +S ++ L+ + VEG L H I + + + Q F+D Sbjct: 241 ILSLYSLALEGINGPLAVLDVEGFPLQKHWYIIYQKSKQLSIVAQTFLD 289 >Cgl0015 [K] COG0583 Transcriptional regulator Length = 298 Score = 115 bits (289), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 77/265 (29%), Positives = 128/265 (48%), Gaps = 8/265 (3%) Query: 18 NIHALRLFYYVAETGSVTKAAARLNISQPAVTSQIKKFEKDLGLPLFNPSGRGVSLTPFG 77 N+ L LF + E GS+ A ++ ++QP + I + E D+ L RG T G Sbjct: 7 NLQTLALFVAIVEEGSLGAGARKVGMAQPNASRAIAELEADMKAELLVRHPRGSHPTAAG 66 Query: 78 IELAKQAGNFFTYEEQIDEFVEDYRHGRKGKLRIAATYLPANFLVPGWAARFKAGYPEIE 137 + L + + + ++ E+V + R + KL + A+ A L+P W A + +P Sbjct: 67 LALVEHSRDLLQSVQEFTEWVTEGRTEQPLKLHVGASMTIAEALLPAWVADMRTRFPACR 126 Query: 138 MEITTTNSQQAFEQLKRHEADVAFYGGGAQDRPEDIDWLELFEDELWFVVSPSHPYAGRT 197 ++++ NS Q E +++ + F P + + ED+L V+SP+H +A RT Sbjct: 127 VDVSVMNSSQVIEAVQKGHLQLGFI--ETPHVPVRLHARVVQEDKLIVVISPNHEWANRT 184 Query: 198 --VSLQEMMLEPFIMREEGSSTRARLVSLCVTYGLKPPQVTLQFSGLGEAIRSVM-AGYG 254 +SL+E+ P I+RE GS TR L L Y + P +Q A+R V+ AG G Sbjct: 185 GRISLRELSETPLIVREVGSGTREALQELLADYDMAEP---IQVLNSNAAVRVVVEAGAG 241 Query: 255 ANFISSLAVREYVEQKRLSRVQVEG 279 + LA+R+++ RL V EG Sbjct: 242 PAVLGELALRDHLALGRLLSVPFEG 266 >sll1594 [K] COG0583 Transcriptional regulator Length = 316 Score = 114 bits (285), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 79/241 (32%), Positives = 128/241 (53%), Gaps = 16/241 (6%) Query: 18 NIHALRLFYYVAETGSVTKAAARLNISQPAVTSQIKKFEKDLGLPLFNPSGRGVSLTPFG 77 +H L++F A GS T+AA L I+QP V+SQIK+ K +GLPLF G+ + LT G Sbjct: 4 TLHQLKVFEATARHGSFTRAAEELYITQPTVSSQIKQLSKTVGLPLFEQIGKRLYLTEAG 63 Query: 78 IELAKQAGNFFTYEEQIDEF---VEDYRHGRKGKLRIAATYLPANFLVPGWAARFKAGYP 134 EL + F +++D F V D + ++G+LR+A A + +P F YP Sbjct: 64 QELLVTCQDIF---QRLDNFAMKVADIKGTKQGRLRLAVIT-TAKYFIPRLLGEFIQKYP 119 Query: 135 EIEMEITTTNSQQAFEQLKRHEADVAFYGGGAQDRPEDID--WLELFEDELWFVVSPSHP 192 IE+ + TN +Q +++ +E D+ + PE+ID + ++ L + HP Sbjct: 120 GIEVSLKVTNHEQIRHRMQNNEDDLYI----VSEPPEEIDLNYQPFLDNPLVVIARRDHP 175 Query: 193 YAGRT-VSLQEMMLEPFIMREEGSSTRARLVSLCVTYGLKPPQVTLQFSGLGEAIRSVMA 251 AG++ + + + E FIMRE+GS TR + +L + + +V L+ G EAI+ +A Sbjct: 176 LAGKSNIPITALNDEAFIMREKGSGTRLAVQNLFHRHYVD-VRVRLEL-GSNEAIKQAIA 233 Query: 252 G 252 G Sbjct: 234 G 234 >all4986 [K] COG0583 Transcriptional regulator Length = 313 Score = 113 bits (282), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 89/309 (28%), Positives = 151/309 (48%), Gaps = 18/309 (5%) Query: 6 TYIYVMKEGILIN---IHALRLFYYVAETGSVTKAAARLNISQPAVTSQIKKFEKDLGLP 62 +Y+ ++ L+N + LR+F A S T+AA L +QP+V+ IK+ + +GLP Sbjct: 3 SYLDLIHRDSLLNSLSLEHLRIFEATARHKSFTRAAEELFTTQPSVSRHIKQLTETIGLP 62 Query: 63 LFNPSGRGVSLTPFGIELAKQAGNFFTYEEQIDEFVEDYRHGRKGKLRIAAT----YLPA 118 LF + LTP G EL F Y E D + D + +G L+++A Y+ Sbjct: 63 LFKYVDNCIQLTPTGEELLIIYKEIFQYLENFDTKLVDLKDINQGYLKVSAVTTSKYVIT 122 Query: 119 NFLVPGWAARFKAGYPEIEMEITTTNSQQAFEQLKRHEADVAFYGGGAQDRPEDIDWLEL 178 N L P F YP+I + + TN + +++ + D FY G + EDI+ ++ Sbjct: 123 NLLQP-----FCKLYPDIRIALEFTNHEAILTRIQDNADD--FYILGYPPKKEDIE-IKP 174 Query: 179 FEDELWFVVSPS-HPYAGR-TVSLQEMMLEPFIMREEGSSTRARLVSLCVTYGLKPPQVT 236 F D VV+PS HP+ + ++SL+ + E IMRE GS TR + L G++ P V Sbjct: 175 FLDNPLVVVAPSNHPFVNQSSISLERLAKEQLIMRERGSETRMAVEMLFAERGIRMP-VK 233 Query: 237 LQFSGLGEAIRSVMAGYGANFISSLAVREYVEQKRLSRVQVEGIQLSNHIAICTRSHESV 296 L+ S ++V+ G G +S + +++ +LS + V+G + I + + Sbjct: 234 LEVSSNNATKQAVLEGLGLAVLSIHTLYPELQRNQLSILNVKGFPILQQWQIAYPKKKWL 293 Query: 297 PPALQQFID 305 P + F++ Sbjct: 294 SPIVSTFLE 302 >MJ0300 [K] COG0583 Transcriptional regulator Length = 296 Score = 108 bits (270), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 74/288 (25%), Positives = 134/288 (46%), Gaps = 6/288 (2%) Query: 19 IHALRLFYYVAETGSVTKAAARLNISQPAVTSQIKKFEKDLGLPLFNPSGRGVSLTPFGI 78 I + F ++T S +KAA RL I+Q V++ I EK LF + GV LTP G Sbjct: 5 ISYFQTFIVASKTKSFSKAAKRLGITQGTVSNHISALEKYFDAQLFLRTPEGVDLTPEGK 64 Query: 79 ELAKQAGNFFTYEEQIDEFVEDYRHGRKGKLRIAATYLPANFLVPGWAARFKAGYPEIEM 138 ++A + + +G +RI A+ P ++P +K+ Y ++ Sbjct: 65 IFYERAEKILDLLNEAKLLMRAIHENPEGIIRIYASTTPGEHILPSIIKEYKSSYKNVDF 124 Query: 139 EITTTNSQQAFEQLKRHEADVAFYGGGAQDRPEDIDWLELFEDELWFVVSPSHPYAGR-T 197 EIT T+S++ F+ L AD+A G + ++ ++ + +D L +V P+HP A + T Sbjct: 125 EITITDSERCFKALDEGLADIAAVG---YLKNKNYEYTIIGKDRLVLIVPPNHPLAEKGT 181 Query: 198 VSLQEMMLEPFIMREEGSSTRARLVSLCVT--YGLKPPQVTLQFSGLGEAIRSVMAGYGA 255 L++++ E +I REEGS TR + Y + V ++ I +V GYG Sbjct: 182 AKLEDILKEDYIDREEGSGTREAFIKALNDKGYSIMDLNVVMRLGSHSAVITAVSEGYGV 241 Query: 256 NFISSLAVREYVEQKRLSRVQVEGIQLSNHIAICTRSHESVPPALQQF 303 + +S + ++ + + V V + + ++ + P A++ F Sbjct: 242 SVVSEIPAKKAEDAGLIKIVPVVDLDVVRYLYLVKSRRPKNPSAVKSF 289 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.137 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 22,912,906 Number of extensions: 901529 Number of successful extensions: 3698 Number of sequences better than 1.0e-05: 1490 Number of HSP's gapped: 3641 Number of HSP's successfully gapped: 1490 Length of query: 314 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 208 Effective length of database: 26,153,027 Effective search space: 5439829616 Effective search space used: 5439829616 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 116 (49.3 bits)