BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0251.0015.p (482 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_phoR_2 [T] COG2202 FOG: PAS/PAC domain 100 1e-20 BS_phoR_3 [T] COG0642 Signal transduction histidine kinase 100 1e-20 ECs0450 [T] COG0642 Signal transduction histidine kinase 99 2e-20 STM0398 [T] COG0642 Signal transduction histidine kinase 92 3e-18 sll0474_2 [T] COG0642 Signal transduction histidine kinase 88 3e-17 >BS_phoR_2 [T] COG2202 FOG: PAS/PAC domain Length = 431 Score = 99.8 bits (247), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 72/233 (30%), Positives = 106/233 (45%), Gaps = 7/233 (3%) Query: 227 TALKSRDEARSNWVAGISHDIRTPLSMILGYASNLEEQVNLTXXXXXXXXXXXXXXXXLR 286 T + + AR N+ A +SH++RTPL+++ GY + EQ + Sbjct: 195 TQMHQLEGARRNFFANVSHELRTPLTVLQGYLEMMNEQPLEGAVREKALHTMREQTQRME 254 Query: 287 SLVSDLNLVSMLEYDMQPLQLKPVRLSTLARTVASDIINNGLDERYPIDLSITDESLQVM 346 LV L +S +E L + V + + R V + L ++ D L+V Sbjct: 255 GLVKQLLTLSKIEAAPTHLLNEKVDVPMMLRVVEREA--QTLSQKKQTFTFEIDNGLKVS 312 Query: 347 GDEKLLYRAVSNLVQNSVQHNPDGCRIVLRSSRGPEDCCYSLSVSDTGAGIAPEHLPELV 406 G+E L A+SNLV N+V H P+G I +R R P + SV D G GIAPEH+P L Sbjct: 313 GNEDQLRSAISNLVYNAVNHTPEGTHITVRWQRVPHGAEF--SVEDNGPGIAPEHIPRLT 370 Query: 407 LLPYSAGRVHPVRQ--GHGLGLPMVARIAEAHKGKLILESGTAQGLHATLQFP 457 Y + RQ G GLGL +V H+ +L +ES +G + P Sbjct: 371 ERFYRVDKARS-RQTGGSGLGLAIVKHAVNHHESRLNIESTVGKGTRFSFVIP 422 >BS_phoR_3 [T] COG0642 Signal transduction histidine kinase Length = 431 Score = 99.8 bits (247), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 72/233 (30%), Positives = 106/233 (45%), Gaps = 7/233 (3%) Query: 227 TALKSRDEARSNWVAGISHDIRTPLSMILGYASNLEEQVNLTXXXXXXXXXXXXXXXXLR 286 T + + AR N+ A +SH++RTPL+++ GY + EQ + Sbjct: 195 TQMHQLEGARRNFFANVSHELRTPLTVLQGYLEMMNEQPLEGAVREKALHTMREQTQRME 254 Query: 287 SLVSDLNLVSMLEYDMQPLQLKPVRLSTLARTVASDIINNGLDERYPIDLSITDESLQVM 346 LV L +S +E L + V + + R V + L ++ D L+V Sbjct: 255 GLVKQLLTLSKIEAAPTHLLNEKVDVPMMLRVVEREA--QTLSQKKQTFTFEIDNGLKVS 312 Query: 347 GDEKLLYRAVSNLVQNSVQHNPDGCRIVLRSSRGPEDCCYSLSVSDTGAGIAPEHLPELV 406 G+E L A+SNLV N+V H P+G I +R R P + SV D G GIAPEH+P L Sbjct: 313 GNEDQLRSAISNLVYNAVNHTPEGTHITVRWQRVPHGAEF--SVEDNGPGIAPEHIPRLT 370 Query: 407 LLPYSAGRVHPVRQ--GHGLGLPMVARIAEAHKGKLILESGTAQGLHATLQFP 457 Y + RQ G GLGL +V H+ +L +ES +G + P Sbjct: 371 ERFYRVDKARS-RQTGGSGLGLAIVKHAVNHHESRLNIESTVGKGTRFSFVIP 422 >ECs0450 [T] COG0642 Signal transduction histidine kinase Length = 431 Score = 99.0 bits (245), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 71/233 (30%), Positives = 106/233 (45%), Gaps = 7/233 (3%) Query: 227 TALKSRDEARSNWVAGISHDIRTPLSMILGYASNLEEQVNLTXXXXXXXXXXXXXXXXLR 286 T + + AR N+ A +SH++RTPL+++ GY ++EQ + Sbjct: 195 TQMHQLEGARRNFFANVSHELRTPLTVLQGYLEMMDEQPLEGAVREKALHTMREQTQRME 254 Query: 287 SLVSDLNLVSMLEYDMQPLQLKPVRLSTLARTVASDIINNGLDERYPIDLSITDESLQVM 346 LV L +S +E L + V + + R V + L ++ D L+V Sbjct: 255 GLVKQLLTLSKIEAAPTQLLNEKVDVPMMLRVVEREA--QTLSQKKQTFTFEIDNGLKVS 312 Query: 347 GDEKLLYRAVSNLVQNSVQHNPDGCRIVLRSSRGPEDCCYSLSVSDTGAGIAPEHLPELV 406 G+E L +SNLV N+V H P+G I +R R P + SV D G GIAPEH+P L Sbjct: 313 GNEDQLRSVISNLVYNAVNHTPEGTHITVRWQRVPHGAEF--SVEDNGPGIAPEHIPRLT 370 Query: 407 LLPYSAGRVHPVRQ--GHGLGLPMVARIAEAHKGKLILESGTAQGLHATLQFP 457 Y + RQ G GLGL +V H+ +L +ES +G + P Sbjct: 371 ERFYRVDKARS-RQTGGSGLGLAIVKHAVNHHESRLNIESTVGKGTRFSFVIP 422 >STM0398 [T] COG0642 Signal transduction histidine kinase Length = 431 Score = 91.7 bits (226), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 70/236 (29%), Positives = 108/236 (45%), Gaps = 13/236 (5%) Query: 227 TALKSRDEARSNWVAGISHDIRTPLSMILGYASNLEEQVNLTXXXXXXXXXXXXXXXXLR 286 T + + AR N+ A +SH++RTPL+++ GY ++EQ + Sbjct: 195 TQMHQLEGARRNFFANVSHELRTPLTVLQGYLEMMQEQALEGATREKALHTMREQTYRME 254 Query: 287 SLVSDLNLVSMLEYDMQPLQLKPVRLSTLARTVASDIINNGLDERYPIDLSITDESLQVM 346 LV L +S +E L + V + + R V + L ++ D+SL V+ Sbjct: 255 GLVKQLLTLSKIEAAPALLLNEKVDVPMMLRVVEREA--QTLSQQKHTFTFEVDDSLSVL 312 Query: 347 GDEKLLYRAVSNLVQNSVQHNPDGCRIVL---RSSRGPEDCCYSLSVSDTGAGIAPEHLP 403 G+E+ L A+SNLV N+V H P G I + R + G E C + D G GIA EH+P Sbjct: 313 GNEEQLRSAISNLVYNAVNHTPAGTHITVSWRRVAHGAEFC-----IQDNGPGIAAEHIP 367 Query: 404 ELVLLPYSAGRVHPVRQ--GHGLGLPMVARIAEAHKGKLILESGTAQGLHATLQFP 457 L Y + RQ G GLGL +V H+ +L ++S +G + P Sbjct: 368 RLTERFYRVDKARS-RQTGGSGLGLAIVKHALNHHESRLEIDSSPGKGTRFSFVLP 422 >sll0474_2 [T] COG0642 Signal transduction histidine kinase Length = 540 Score = 88.2 bits (217), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 71/277 (25%), Positives = 126/277 (45%), Gaps = 14/277 (5%) Query: 202 VETGGIFSDLSESINLASATLQAKNTALKSRDEARSNWVAGISHDIRTPLSMILGYASNL 261 V+ G +D++E I A L+ N L + + ++A +SH++RTPL+ ILG L Sbjct: 265 VKIIGTIADITE-IKKAEEQLKLSNKILAKATQLKDEFLANMSHELRTPLNSILGMIETL 323 Query: 262 EEQVN--LTXXXXXXXXXXXXXXXXLRSLVSDLNLVSMLEYDMQPLQLKPVRLSTLARTV 319 + QV L L SL++D+ +S +E L L P +S L Sbjct: 324 QNQVYGPLNGKQVQSLEIVENSGRHLLSLINDILDLSKIEAGRMDLDLNPTSVSALVNHS 383 Query: 320 ASDIINNGLDERYPIDLSITDESLQVMGDEKLLYRAVSNLVQNSVQHNPDGCRIVLRSS- 378 + + + ++ + I V+ D++ L + + NL+ N+++ P+G ++V+++ Sbjct: 384 LTFVQQFAIQKQINLSSEIIPNLPDVLVDKRRLCQVLINLLNNAIKFTPEGGKVVVQADL 443 Query: 379 ---RGPEDC----CYSLSVSDTGAGIAPEHLPELVLLPYSA--GRVHPVRQGHGLGLPMV 429 +G E+ S +V DTG GI + L + P+ ++ G GLGL +V Sbjct: 444 IKEQGKENSQSPPQLSFTVFDTGIGIEADRLNN-IFEPFVQIDSALNRRYDGTGLGLSLV 502 Query: 430 ARIAEAHKGKLILESGTAQGLHATLQFPAWPADSSGP 466 +I E H G + + S +G + P D GP Sbjct: 503 KKIVELHGGSVTVTSKLNEGSRFKITIPCVFQDKDGP 539 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.316 0.135 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 30,380,412 Number of extensions: 1130213 Number of successful extensions: 12021 Number of sequences better than 1.0e-05: 127 Number of HSP's gapped: 11920 Number of HSP's successfully gapped: 127 Length of query: 482 Length of database: 38,378,431 Length adjustment: 110 Effective length of query: 372 Effective length of database: 25,691,691 Effective search space: 9557309052 Effective search space used: 9557309052 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 118 (50.1 bits)