BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0251.0013.p (296 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value all2672 [V] COG1131 ABC-type multidrug transport system, ATPase ... 186 4e-47 BH0290 [V] COG1131 ABC-type multidrug transport system, ATPase c... 180 2e-45 sll0489 [V] COG1131 ABC-type multidrug transport system, ATPase ... 168 8e-42 MTH1370 [V] COG1131 ABC-type multidrug transport system, ATPase ... 157 2e-38 PA4037 [V] COG1131 ABC-type multidrug transport system, ATPase c... 155 5e-38 >all2672 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 293 Score = 186 bits (472), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 100/282 (35%), Positives = 167/282 (59%), Gaps = 6/282 (2%) Query: 3 LVLNKLTKQFGRK-TAVDQMTITMKPGVYGLLGANGAGKTTLMRMVCGVLNPTAGDVYLD 61 L++ +L K++ A+ +++ + G++GLLG NGAGK++LMR + + + +G + LD Sbjct: 2 LIIKQLNKKYPNGIQALRDISLKIDYGIFGLLGPNGAGKSSLMRTLATLQDADSGSIELD 61 Query: 62 GKRAADLGEEYRSLLGYLPQDFGYYPDFTAGEFMLYVAALKG-ISPEKARIRSKELLALV 120 G + RS+LGYLPQDFG YP +A + + +A KG I ++ R + L LV Sbjct: 62 GVNFLKNPQSARSILGYLPQDFGVYPSVSAEDLLDQLAVFKGFIHHQQRREIVAQQLQLV 121 Query: 121 GLTEVSAKKIRTFSGGMKQRLGIAQAVLNDPRILVLDEPTAGLDPKERVHFRNLIANFSK 180 L E +K+ TFSGGM+QR GIAQA+L P+++++DEPTAGLDP ER+ F NL++ S+ Sbjct: 122 NLYEQRQQKLGTFSGGMRQRFGIAQALLGSPKLVIVDEPTAGLDPAERIRFHNLLSEISQ 181 Query: 181 DKIVILSTHIVSDIEYISDTVLMIKDGKLIINRPADNIAHEMDGKVWRCVVAKEAAPAIS 240 D++++LSTHIV D+ + + ++ G+++ + + + ++G+VW + E + Sbjct: 182 DRVLLLSTHIVEDVAELCPNMAIMNRGEILRSGSPQALINALNGRVW-TALHSETSNVEE 240 Query: 241 SSFCVANLHHGDDDTVILRVLSDELPMDGAMNEIPTLEDLYL 282 + + + G+ +RVLSD P P L D+Y Sbjct: 241 LTVITSRMSRGER---WVRVLSDSQPGKDFQPVEPDLNDVYF 279 >BH0290 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 301 Score = 180 bits (457), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 107/249 (42%), Positives = 153/249 (61%), Gaps = 24/249 (9%) Query: 1 MELVLNKLTKQFGRKTAVDQMTITMKPG-VYGLLGANGAGKTTLMRMVCGVLNPTAGDVY 59 M+L + +TK++ KTAV ++ + G GL+G NGAGKTTL++M+ +L+PT GD+ Sbjct: 1 MKLEIKSVTKKYKEKTAVHDFSMDLLSGECVGLIGPNGAGKTTLIKMITNILDPTRGDIL 60 Query: 60 LDGKRAADLGEEYRSLLGYLPQDFGYYPDF----TAGEFMLYVAALKGISPEKARIRSKE 115 L+GKR +++ E +GYLPQ YPDF TA E +L++ L GIS +K E Sbjct: 61 LNGKRISEMKRE----IGYLPQ----YPDFYQWMTASETLLFMGQLSGISKKKLTKSIPE 112 Query: 116 LLALVGLTEVSAKKIRTFSGGMKQRLGIAQAVLNDPRILVLDEPTAGLDPKERVHFRNLI 175 +L+ VGL K+ TFSGGMKQRLGIAQA+L+ P +V+DEP + LDP R N+I Sbjct: 113 ILSKVGLRGEENSKVSTFSGGMKQRLGIAQALLHKPSFIVMDEPVSALDPIGRREVLNII 172 Query: 176 ANFSKDKIVILSTHIVSDIEYISDTVLMIKDGKLI--------INRPADN-IAHEM--DG 224 KD ++LSTHI++D E I + ++MIK+G+ I +NR + N I E+ + Sbjct: 173 EEIKKDSTILLSTHILADAEEICERLVMIKNGEKIEDTTMMELLNRNSKNKIRVEITDES 232 Query: 225 KVWRCVVAK 233 K W VV K Sbjct: 233 KDWIEVVKK 241 >sll0489 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 342 Score = 168 bits (426), Expect = 8e-42, Method: Compositional matrix adjust. Identities = 90/243 (37%), Positives = 142/243 (58%), Gaps = 4/243 (1%) Query: 8 LTKQFGRKTAVDQMTITMKPG-VYGLLGANGAGKTTLMRMVCGVLNPTAGDVYLDGKRAA 66 L+K +G TA+ + +++ G + G LG NGAGKTT MR++ G + T G V + G Sbjct: 7 LSKVYGSTTAIQNVDFSVQKGEILGFLGPNGAGKTTTMRILAGYIPATTGTVRVAGFDVH 66 Query: 67 DLGEEYRSLLGYLPQDFGYYPDFTAGEFMLYVAALKGISPEKARIRSKELLALVGLTEVS 126 + R +GYLP++ Y D T F+ +VA++KG+ P R R + LTE Sbjct: 67 EQSLAVRKRIGYLPENPPLYGDMTVASFLNFVASIKGVKPGDRRQRVIWAMERCQLTEKR 126 Query: 127 AKKIRTFSGGMKQRLGIAQAVLNDPRILVLDEPTAGLDPKERVHFRNLIANFSKDKIVIL 186 IR S G KQR+GIAQA+++DP +++LDEPT GLDPK+ + RNLI + ++D +IL Sbjct: 127 KVLIRKLSKGFKQRVGIAQAIVHDPAVIILDEPTVGLDPKQIIEVRNLIKSLAEDHTIIL 186 Query: 187 STHIVSDIEYISDTVLMIKDGKLIINRPADNIAHEMDGKV-WRCVVAKEAAPAISSSFCV 245 STHI+ ++ D V +I G+++ DN+ E+ G + ++ VA A ++ + C+ Sbjct: 187 STHILPEVSMTCDRVTIINQGRVVATNTPDNLLAELKGNLSYQLEVA--GAEGMAIAHCL 244 Query: 246 ANL 248 +L Sbjct: 245 QSL 247 >MTH1370 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 268 Score = 157 bits (398), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 10/207 (4%), Positives = 32/207 (15%), Gaps = 1/207 (0%) Query: 5 LNKLTKQFGRKTAVDQMTITMKPG-VYGLLGANGAGKTTLMRMVCGVLNPTAGDVYLDGK 63 L T + + + + ++ + + + Sbjct: 21 LKIKTYKVVLIARAASIFGVKRIVIYHDDADGEARFIRDILTYMDTPQYLRRKVFPIMRE 80 Query: 64 RAADLGEEYRSLLGYLPQDFGYYPDFTAGEFMLYVAALKGISPEKARIRSKELLALVGLT 123 + +E L + + Sbjct: 81 LKHVGILPPLRTPHHPTGKPVTGEYRQGLTVKRVKKGTLVDIGADKLALCREKLTVNRIM 140 Query: 124 EVSAKKIRTFSGGMKQRLGIAQAVLNDPRILVLDEPTAGLDPKERVHFRNLIANFSKDKI 183 ++ + + V + A+ + Sbjct: 141 SFRVVRLGKEILIEPDEPEDRYWGYEVLDTRRNLAESLKTVGADVVVATSRNASPITSIL 200 Query: 184 VILSTHIVSDIEYISDTVLMIKDGKLI 210 + T + E K I Sbjct: 201 DEVKTRMRGAREAAILFGGPYKGLPEI 227 >PA4037 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 308 Score = 155 bits (393), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 80/219 (36%), Positives = 134/219 (61%), Gaps = 5/219 (2%) Query: 5 LNKLTKQFGRKTAVDQMTITMKPG-VYGLLGANGAGKTTLMRMVCGVLNPTAGDVYLDGK 63 +++L+K+F +T V+ ++ + G + GLLG NGAGK+T ++M+ G L P+AG V + G Sbjct: 4 IDRLSKRFSGRTVVNDLSFRIDRGEIVGLLGPNGAGKSTTLKMLSGFLAPSAGSVRIFGF 63 Query: 64 RAADLGEEYRSLLGYLPQDFGYYPDFTAGEFMLYVAALKGISPEKARIRSKELLALVGLT 123 D + + L+GYLP++ Y + T F+ +VA+++ S + R R + + L Sbjct: 64 DMQDKARQAQKLIGYLPENAPSYGEMTVEGFLAFVASIRDYSGREKRRRIDSAMDCMELR 123 Query: 124 EVSAKKIRTFSGGMKQRLGIAQAVLNDPRILVLDEPTAGLDPKERVHFRNLIANFSKDKI 183 + I T S G K+R+ +AQA+L+DP +L+LDEPT GLDP ++ R L+ N S+ KI Sbjct: 124 DERRSIIETLSKGFKRRVALAQAILHDPELLLLDEPTDGLDPNQKHQVRQLVKNLSESKI 183 Query: 184 VILSTHIVSDIEYISDTVLMIKDGKLIINRPADNIAHEM 222 V++STHI+ ++ ++ L+I G+L+ ADN E+ Sbjct: 184 VVISTHILEEVSFMCSRALVINGGRLL----ADNTPGEL 218 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.138 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 22,726,914 Number of extensions: 1017341 Number of successful extensions: 7882 Number of sequences better than 1.0e-05: 2104 Number of HSP's gapped: 5323 Number of HSP's successfully gapped: 2294 Length of query: 296 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 190 Effective length of database: 26,153,027 Effective search space: 4969075130 Effective search space used: 4969075130 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 115 (48.9 bits)