BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0250.0011.p (99 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0224 [TK] COG0745 Response regulators consisting of a CheY-li... 86 1e-17 CAC0371 [TK] COG0745 Response regulators consisting of a CheY-li... 86 2e-17 BH0755 [TK] COG0745 Response regulators consisting of a CheY-lik... 83 1e-16 SP2082 [TK] COG0745 Response regulators consisting of a CheY-lik... 77 7e-15 Rv0491 [TK] COG0745 Response regulators consisting of a CheY-lik... 76 1e-14 >CAC0224 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 223 Score = 85.9 bits (211), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 37/89 (41%), Positives = 62/89 (69%), Gaps = 1/89 (1%) Query: 1 LILLDINLGQTSGFELCKRLRKTMKAPILFISARSSDDDILIALNIGGDDYTHKPYTLSV 60 L+L+DINL GF C ++R K P++F+S+RSS+ D+++A+N+GGDDY KP+++ + Sbjct: 48 LVLMDINLPVCDGFYWCSKIRNISKVPVIFLSSRSSNMDVVMAVNMGGDDYITKPFSIEI 107 Query: 61 LLAKVRAVLKRYGGQYTVEAPEILEFGKV 89 L+AK+ A+L+R Y+ + +EF V Sbjct: 108 LMAKINAILRR-TYSYSETEMDTIEFKDV 135 >CAC0371 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 228 Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 39/84 (46%), Positives = 59/84 (70%) Query: 1 LILLDINLGQTSGFELCKRLRKTMKAPILFISARSSDDDILIALNIGGDDYTHKPYTLSV 60 L+LLD+NL GF LC+ R+ KAPI+F+SARSS+ + + L +G DDY KP++ + Sbjct: 48 LVLLDVNLPYYDGFNLCRIFRRKSKAPIIFMSARSSEIEQIRGLEMGADDYITKPFSFEL 107 Query: 61 LLAKVRAVLKRYGGQYTVEAPEIL 84 LLAKV+A ++R G+Y+ + E+L Sbjct: 108 LLAKVQASIRRTYGEYSEDNSEVL 131 >BH0755 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 232 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 40/78 (51%), Positives = 54/78 (69%) Query: 1 LILLDINLGQTSGFELCKRLRKTMKAPILFISARSSDDDILIALNIGGDDYTHKPYTLSV 60 L+LLDINL GF C++LR+ PI+F+SAR+S+ D + A+ GGDDY KP+ L V Sbjct: 48 LVLLDINLPAFDGFYWCRQLRRLSNLPIIFLSARASEMDQVYAIENGGDDYITKPFHLEV 107 Query: 61 LLAKVRAVLKRYGGQYTV 78 LLAKV+ VL+R G Y + Sbjct: 108 LLAKVKGVLRRSYGDYAI 125 >SP2082 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 235 Score = 77.0 bits (188), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 39/76 (51%), Positives = 54/76 (71%), Gaps = 1/76 (1%) Query: 1 LILLDINLGQTSGFELCKRLR-KTMKAPILFISARSSDDDILIALNIGGDDYTHKPYTLS 59 ILLDI L Q G E+CKRLR K +K PI+ +SA+S + D ++AL +G DDY KP++ Sbjct: 49 FILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLTKPFSPR 108 Query: 60 VLLAKVRAVLKRYGGQ 75 LLA+V+AVL+R G+ Sbjct: 109 ELLARVKAVLRRTKGE 124 >Rv0491 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 227 Score = 76.3 bits (186), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 36/90 (40%), Positives = 58/90 (64%) Query: 1 LILLDINLGQTSGFELCKRLRKTMKAPILFISARSSDDDILIALNIGGDDYTHKPYTLSV 60 ++LLD+ L SG ++CK+LR P++ ++AR S+ D ++ L +G DDY KPY+ Sbjct: 48 IVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARE 107 Query: 61 LLAKVRAVLKRYGGQYTVEAPEILEFGKVR 90 L+A++RAVL+R G + + +LE G VR Sbjct: 108 LIARIRAVLRRGGDDDSEMSDGVLESGPVR 137 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.324 0.142 0.412 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 7,161,257 Number of extensions: 268733 Number of successful extensions: 1089 Number of sequences better than 1.0e-05: 229 Number of HSP's gapped: 1091 Number of HSP's successfully gapped: 229 Length of query: 99 Length of database: 38,378,431 Length adjustment: 68 Effective length of query: 31 Effective length of database: 30,535,719 Effective search space: 946607289 Effective search space used: 946607289 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 109 (46.6 bits)