BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0249.0011.p (240 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin0584 [K] COG2188 Transcriptional regulators 132 4e-31 lin0901 [K] COG2188 Transcriptional regulators 130 1e-30 BH3917 [K] COG2188 Transcriptional regulators 124 2e-28 BS_ydhQ [K] COG2188 Transcriptional regulators 122 6e-28 SP2020 [K] COG2188 Transcriptional regulators 117 1e-26 >lin0584 [K] COG2188 Transcriptional regulators Length = 242 Score = 132 bits (332), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 80/242 (33%), Positives = 138/242 (57%), Gaps = 17/242 (7%) Query: 2 SQFVYKQIIDDLKMKIFAGQFA-DMRLPDERSLSETYQVSRSSIKRALMKMENSGIIFKK 60 +Q Y I ++++ +I + + +PDE +L++ + SR ++K+AL + G++++K Sbjct: 4 NQTKYSFIAEEIRKRIMNHAYPLNQPIPDEITLAKEFDCSRMTMKKALEVLVLEGLLYRK 63 Query: 61 RGSGTFI-------NPLYIKNESIFNYEGTNLGVTDNFQMDGKKPKVKVLNFEVIRPTEE 113 RG GTFI + L I N+ + + T L +DGKK KV+ F+VI PTEE Sbjct: 64 RGHGTFIIKSALDADRLQIHNQEVNGF--TKL-------LDGKKVISKVIEFKVIFPTEE 114 Query: 114 LQRDLFLQPHDFVYKIIRLRLFDDEPFMIETGYIPIKIVQNLDQTIIEGSIFHYLEESRN 173 + L ++ +Y I+R+RL DEP+++E Y+P+ ++ ++Q I+EGSI+ Y+++ N Sbjct: 115 IAERLHIEMETPIYDILRVRLVKDEPYVLEHTYMPVGVIPGINQQILEGSIYSYIQDDLN 174 Query: 174 LAVTKSFLSIFAEPSGTHDQELLHLQDNEPVGIMEGIFFLDNGTPFEFSHMRFHYKYLKF 233 L + S+ I A+ + DQ+ L ++PV +E +L+NG FEFS R Y F Sbjct: 175 LKIASSYKQIRADKATLLDQQYLDCASDDPVVEVEQTVYLNNGLAFEFSRSRHRYDKFVF 234 Query: 234 NT 235 T Sbjct: 235 TT 236 >lin0901 [K] COG2188 Transcriptional regulators Length = 237 Score = 130 bits (328), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 76/232 (32%), Positives = 132/232 (56%), Gaps = 10/232 (4%) Query: 6 YKQIIDDLKMKIFAGQFA-DMRLPDERSLSETYQVSRSSIKRALMKMENSGIIFKKRGSG 64 Y+ I +++ KI G + + LPD+ SLS Y SR +IK+A + G+++++RG+G Sbjct: 4 YELIAAEIREKINNGTYPPESILPDQVSLSRAYDCSRMTIKKAFDVLALEGLVYRQRGAG 63 Query: 65 TFI--NPLYIKNE-SIFNYEGTNLGVTDNFQMDGKKPKVKVLNFEVIRPTEELQRDLFLQ 121 TF+ N L K + S+ +Y+G + DN + + K++ F++ P E+ Q L ++ Sbjct: 64 TFVMKNALANKQDASLRDYDGLTKMMGDN------RIRSKIIAFDIAFPDEKTQEQLLIK 117 Query: 122 PHDFVYKIIRLRLFDDEPFMIETGYIPIKIVQNLDQTIIEGSIFHYLEESRNLAVTKSFL 181 VYK+IRLRL D EP+++E +P +V L + I+ SI+ YL+++ L ++ +F Sbjct: 118 ADQPVYKLIRLRLLDGEPYVLEHTTMPADLVPGLTREILHHSIYAYLQDTLGLVLSGAFR 177 Query: 182 SIFAEPSGTHDQELLHLQDNEPVGIMEGIFFLDNGTPFEFSHMRFHYKYLKF 233 I A+ +DQE L +++PV +E + +L +G P E+S R Y F Sbjct: 178 KINADKPSEYDQEYLACGEHDPVLEVEQVVYLKDGRPVEYSRSRHRYDTRSF 229 >BH3917 [K] COG2188 Transcriptional regulators Length = 261 Score = 124 bits (310), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 78/234 (33%), Positives = 125/234 (53%), Gaps = 7/234 (2%) Query: 6 YKQIIDDLKMKIFAGQF-ADMRLPDERSLSETYQVSRSSIKRALMKMENSGIIFKKRGSG 64 Y+ I ++K +I + D +PDE SLS+ + SR ++KRAL + G++++KRG G Sbjct: 27 YEAISMEIKKRIKENDYPVDQPIPDEISLSKEFGCSRMTMKRALDILVMEGLLYRKRGHG 86 Query: 65 TFI--NPLYIKNESIFNYEGTNLGVTDNFQMDGKKPKVKVLNFEVIRPTEELQRDLFLQP 122 TFI + ++ ++ E L N D K+ KV+ F V P EE+ L + Sbjct: 87 TFIVQSAIHTSRVNVLTNEVKGLS---NLLKD-KQVTSKVIQFNVEFPAEEVAAHLAIDQ 142 Query: 123 HDFVYKIIRLRLFDDEPFMIETGYIPIKIVQNLDQTIIEGSIFHYLEESRNLAVTKSFLS 182 VY IIRLRL D EP++IE Y+P ++ ++ ++ GSI+ YL + L + S Sbjct: 143 KTPVYHIIRLRLVDGEPYVIEKTYMPTPLIPGINDEVLHGSIYSYLIDKLGLTIAGSHRK 202 Query: 183 IFAEPSGTHDQELLHLQDNEPVGIMEGIFFLDNGTPFEFSHMRFHYKYLKFNTF 236 I A + + E LH + ++P+ +E + FL+NG PFE+S R Y + T Sbjct: 203 IRACKAEALEIEHLHCEADDPILEVEHVGFLNNGVPFEYSFSRHRYDKFEVTTI 256 >BS_ydhQ [K] COG2188 Transcriptional regulators Length = 418 Score = 122 bits (305), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 8/224 (3%), Positives = 34/224 (15%), Gaps = 3/224 (1%) Query: 6 YKQIIDDLKMKIFAGQFA-DMRLPDERSLSETYQVSRSSIKRALMKMENSGIIFKKRGSG 64 + + R+ Sbjct: 4 DAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENTVVTGAGWLKVATGGIAKCT 63 Query: 65 TFINPLYIKNESIFNYEGTNLGVTDNFQMDGKKPKVKVLNFEVIRPTEELQRDLFLQPHD 124 + N + + + + L + Sbjct: 64 QYGNNGTLSVSDGAIATDIVQSEGG--AISLSTLATVNGRHPEGEFSVDKGYACGLLLEN 121 Query: 125 FVYKIIRLRLFDDEPFMIETGYIPIKIVQNLDQTIIEGSIFHYLEESRNLAVTKSFLSIF 184 + ++ + + G + + + G + Y + Sbjct: 122 GGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGELLVYPGGEASNCEINQGGVFM 181 Query: 185 AEPSGTHDQELLHLQDNEPVGIMEGIFFLDNGTPFEFSHMRFHY 228 + +N + I + ++ + Sbjct: 182 LAGKASDTLLAGGTMNNLGGEDSDTIVENGSIYRLGTDGLQLYS 225 >SP2020 [K] COG2188 Transcriptional regulators Length = 242 Score = 117 bits (293), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 69/230 (30%), Positives = 124/230 (53%), Gaps = 1/230 (0%) Query: 9 IIDDLKMKIFAGQFA-DMRLPDERSLSETYQVSRSSIKRALMKMENSGIIFKKRGSGTFI 67 I ++++ KI ++ + +LPDE +L++ + SR +IK+AL + + G+IF+KRG GTF+ Sbjct: 8 IYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTIKKALDLLVSEGLIFRKRGQGTFV 67 Query: 68 NPLYIKNESIFNYEGTNLGVTDNFQMDGKKPKVKVLNFEVIRPTEELQRDLFLQPHDFVY 127 + E G+T + ++++F++ E L L + VY Sbjct: 68 LSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRIIHFKLEFANEFLAEKLQVALQSPVY 127 Query: 128 KIIRLRLFDDEPFMIETGYIPIKIVQNLDQTIIEGSIFHYLEESRNLAVTKSFLSIFAEP 187 I RLR+ D +P+++E Y+ ++ + + I++ SI++Y+E L + + + A Sbjct: 128 NIYRLRIIDGKPYVLEQTYMSTDVIPGITEDILQKSIYNYIEGKLGLHIASATKILRASS 187 Query: 188 SGTHDQELLHLQDNEPVGIMEGIFFLDNGTPFEFSHMRFHYKYLKFNTFV 237 S ++Q L L EPV +E + +LDNGTPFE+S R Y +FN+F Sbjct: 188 SSENEQHYLQLLPTEPVFEVEQVAYLDNGTPFEYSISRHRYDLFEFNSFA 237 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.323 0.141 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 17,240,165 Number of extensions: 652615 Number of successful extensions: 1567 Number of sequences better than 1.0e-05: 83 Number of HSP's gapped: 1519 Number of HSP's successfully gapped: 83 Length of query: 240 Length of database: 38,378,431 Length adjustment: 103 Effective length of query: 137 Effective length of database: 26,499,029 Effective search space: 3630366973 Effective search space used: 3630366973 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 114 (48.5 bits)