BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0249.0005.p (1032 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2013_3 [T] COG2972 Predicted signal transduction protein with ... 209 3e-53 BH1547_3 [T] COG2972 Predicted signal transduction protein with ... 201 6e-51 VC0622_1 [T] COG0642 Signal transduction histidine kinase 157 1e-37 BS_ywpD_2 [T] COG2972 Predicted signal transduction protein with... 156 2e-37 MA1149_2 [T] COG0642 Signal transduction histidine kinase 148 5e-35 >BH2013_3 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 216 Score = 209 bits (531), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 105/215 (48%), Positives = 141/215 (65%), Gaps = 2/215 (0%) Query: 817 ALTQLKTSIDDRLRMESAWLQSQIQPHFLFNTLNSIAALGMIDFNKMQTLLDEFSNYLRL 876 A+ +LK SI +RLRME+AWLQ+QIQPHFLFNTLN+IA+L ID +M LL++F +LR Sbjct: 2 AVIELKHSIQERLRMEAAWLQAQIQPHFLFNTLNTIASLSEIDTKRMAALLEKFGQFLRK 61 Query: 877 SFDFKNASPLVPLEHELSLVRSYVYIEKERFGSRLTVVWNIESGIDILIPPLSIQPLVEN 936 SFD +N LVP+ HEL+L SYVYIE+ERFG RL V W+ + + +PPLSIQPLVEN Sbjct: 62 SFDGQNIHSLVPITHELALTESYVYIEQERFGERLKVHWDKDEHVVCNLPPLSIQPLVEN 121 Query: 937 AIKHGLLSRNRGGTVSVNVCRLAEMVXXXXXXXXXXXXXXYLSQLLTYSNRSSSRSGIGL 996 A+KHG+L + GG V + + + E V L+ +LT + SGIG+ Sbjct: 122 ALKHGVLKKPEGGNVHIRIKKQEETVKIMITDDGVGMDKATLNNVLT--RKPDQVSGIGM 179 Query: 997 ININRRLMQQFGTGLDIQSSLDQGTCVSFQIPYQK 1031 +N + RL Q FG GL ++S +GT +SF +P K Sbjct: 180 LNTDLRLKQLFGKGLFVESQPGKGTSISFYVPLNK 214 >BH1547_3 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 218 Score = 201 bits (510), Expect = 6e-51, Method: Compositional matrix adjust. Identities = 106/214 (49%), Positives = 137/214 (64%), Gaps = 3/214 (1%) Query: 817 ALTQLKTSIDDRLRMESAWLQSQIQPHFLFNTLNSIAALGMIDFNKMQTLLDEFSNYLRL 876 ALT+ K SI D+LRME AWLQ+QIQPHFLFNTLN+I AL ID +MQ LL+ F+++L+ Sbjct: 2 ALTEAKQSIRDQLRMEGAWLQAQIQPHFLFNTLNAILALSEIDIKRMQKLLEVFADFLKN 61 Query: 877 SFDFKNASPLVPLEHELSLVRSYVYIEKERFGSRLTVVWNIESGIDILIPPLSIQPLVEN 936 F F N L P+E ELS V+SY+YIEKERF RL V W +E ++IP +IQPLVEN Sbjct: 62 KFTFTNLDELAPIEIELSTVQSYLYIEKERFAQRLNVRWEVEDCKALMIPLFTIQPLVEN 121 Query: 937 AIKHGLLSRNRGGTVSVNVCRLAEMVXXXXXXXXXXXXXXYLSQLLTYSNRSSSRSGIGL 996 A+KHG L+R+ GG +++ + V + LLT R S+RSGIGL Sbjct: 122 AVKHG-LNRSSGGEITIKIKNEDTYVKVTVTDNGVGMDENIVQHLLT--ERPSARSGIGL 178 Query: 997 ININRRLMQQFGTGLDIQSSLDQGTCVSFQIPYQ 1030 N + RL + +G GL I+S L GT VSF + Q Sbjct: 179 RNTDMRLKRHYGKGLHIESKLGVGTSVSFLVQKQ 212 >VC0622_1 [T] COG0642 Signal transduction histidine kinase Length = 769 Score = 157 bits (396), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 98/274 (35%), Positives = 147/274 (53%), Gaps = 4/274 (1%) Query: 425 KLQLEDKRKDEFLVNTSHELRNPLQGISTMLQVILDDQSHPVHPKQQERVEIIKKVSSRM 484 +LQL +K KDEFL TSHELR PL G+ + + ++ + P+ + +++II R+ Sbjct: 500 ELQLANKLKDEFLATTSHELRTPLHGMIGIAEALISGANGPISAAHKYQLDIIISSGQRL 559 Query: 485 SFMLDDLIDITRLKEQTIPLEIKPVRLQSVVSGVLDMIKVMLDGKPVQLRADIEDTFPAV 544 + ++DDL+D +++ + ++ V L S VL++ +L K +++ + + V Sbjct: 560 ATLVDDLLDYHKMRYGALDIQRCAVDLSSATRLVLELSHHLLGKKTLRIINQVSEQPVWV 619 Query: 545 QADEQRVIQILFNLLHNAVKFTDKGFITVRAVRKGPMAEVQVEDTGIGIPEEALLQIFHP 604 AD QR+ Q+L+NL+ NA+K+T +G I + A VQV DTG GIP E L IF P Sbjct: 620 SADPQRLEQVLYNLIGNAIKYTSEGKIVISATYIDDKVRVQVVDTGQGIPAEQLEHIFEP 679 Query: 605 YEQADNHFKRASGGFGLGLSICRQLVELHGGTITAESSLGEKTLFRFTLPLGDGNPAEED 664 QA + R G GLGLSI RQL+EL GT+ S T F FTLPL +EE+ Sbjct: 680 LIQAGHDASRYRQGAGLGLSISRQLIELMHGTLYVSSQPMVGTTFSFTLPLA----SEEE 735 Query: 665 FQPSSLTNLSVPLDEIAAAAEPPVERGISPNESG 698 + LT L +E P + + NE G Sbjct: 736 IAQARLTELPHFQAPEVLDSELPEQSNLPENEHG 769 >BS_ywpD_2 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 218 Score = 156 bits (394), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 86/200 (43%), Positives = 122/200 (61%), Gaps = 7/200 (3%) Query: 830 RMESAWLQSQIQPHFLFNTLNSIAALGMIDFNKMQTLLDEFSNYLRLSFDFKNASPLVPL 889 RME A+LQSQI+PHFL+N LN+I +L +D K + + +EF+NYLR+SFDF+N S + Sbjct: 6 RMEMAFLQSQIKPHFLYNVLNTIISLTHLDIEKAREVTEEFTNYLRMSFDFQNTSAISSF 65 Query: 890 EHELSLVRSYVYIEKERFGSRLTVVWNIESGIDILIPPLSIQPLVENAIKHGLLSRNRGG 949 HELS++ SY+ IEK RF +RL V+++I+ ID ++PPL IQPLVENA+ HG+ + GG Sbjct: 66 RHELSIINSYLSIEKTRFSNRLEVLFDIDEDIDFILPPLMIQPLVENAVLHGVSKKRGGG 125 Query: 950 TVSVNVCRLA--EMVXXXXXXXXXXXXXXYLSQLLTYSNRSSSRSGIGLININRRLMQQF 1007 + + + + E + L T +RS +GL NIN+RL Sbjct: 126 WIKLTAKKQSKNEYHIKVEDNGPGITPEKQIDLLSTDFDRS-----VGLKNINQRLKHFC 180 Query: 1008 GTGLDIQSSLDQGTCVSFQI 1027 G+ L I S+ D GT VS I Sbjct: 181 GSELMISSTPDAGTSVSMLI 200 >MA1149_2 [T] COG0642 Signal transduction histidine kinase Length = 279 Score = 148 bits (373), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 83/255 (32%), Positives = 143/255 (56%), Gaps = 7/255 (2%) Query: 421 LLAGKLQLE--DKRKDEFLVNTSHELRNPLQGISTMLQVILDDQSHPVHPKQQERVEIIK 478 +L K+ E ++ K F+VN SHELR PL + ++L + + P++ KQ+ E I Sbjct: 7 MLQAKMAAEAANRAKINFIVNMSHELRTPLNAVIGFSDLLLSETAGPLNEKQKRYTENIS 66 Query: 479 KVSSRMSFMLDDLIDITRLKEQTIPLEIKPVRLQSVVSGVLDMIKVMLDGKPVQLRADIE 538 K S + +++D++DI+RL+ I L + V + V+ V ++ + K +++ +E Sbjct: 67 KSGSHLLDVINDVLDISRLELGNIELYYETVDIPGVIEEVRRVLSSLSAEKNIRIEYKVE 126 Query: 539 DTFPAVQADEQRVIQILFNLLHNAVKF-TDKGFITVRAVRKGPMAEVQVEDTGIGIPEEA 597 + D + QIL+NLL+NA+KF ++ G + ++A +G M E+ V+D GIGI E Sbjct: 127 QGLKTIDVDRVKFKQILYNLLNNAIKFSSEDGKVNIKARSEGDMVEISVKDEGIGINEAD 186 Query: 598 LLQIFHPYEQADNHFKRASGGFGLGLSICRQLVELHGGTITAESSLGEKTLFRFTLPLGD 657 ++F P+ Q D R GG GLGL++ ++ VELHGG + E+S G+ + F F +P Sbjct: 187 YARVFLPFVQIDESISRKHGGVGLGLALVKRFVELHGGQVWVEASPGKGSTFTFRIP--- 243 Query: 658 GNPAEEDFQPSSLTN 672 E++ + +TN Sbjct: 244 -KRPEKEIKEKEVTN 257 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.137 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 68,400,108 Number of extensions: 2764259 Number of successful extensions: 6927 Number of sequences better than 1.0e-05: 666 Number of HSP's gapped: 6354 Number of HSP's successfully gapped: 667 Length of query: 1032 Length of database: 38,378,431 Length adjustment: 116 Effective length of query: 916 Effective length of database: 24,999,687 Effective search space: 22899713292 Effective search space used: 22899713292 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 121 (51.2 bits)