BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0247.0008.p (331 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH0411 [K] COG2378 Predicted transcriptional regulator 165 9e-41 lin0464 [K] COG2378 Predicted transcriptional regulator 79 1e-14 lin0395 [K] COG2378 Predicted transcriptional regulator 65 2e-10 lin2535 [K] COG2378 Predicted transcriptional regulator 57 3e-08 lin0383 [K] COG2378 Predicted transcriptional regulator 51 3e-06 >BH0411 [K] COG2378 Predicted transcriptional regulator Length = 331 Score = 165 bits (418), Expect = 9e-41, Method: Compositional matrix adjust. Identities = 100/311 (32%), Positives = 157/311 (50%), Gaps = 4/311 (1%) Query: 1 MRADRXXXXXXXXQNRGKVTSRELAGTLEVSERTIFRDMEALSASGIPVLAERGREGGWM 60 M+ADR QN K+T+ +L L VS RTI RDM+ LSA GIP+++ERGR GGW Sbjct: 1 MKADRLLEIVALLQNHEKLTTHQLVDHLHVSSRTILRDMDTLSALGIPIVSERGRAGGWK 60 Query: 61 LTEGYRTSLTGMKPKEIGALQLSADPSILQDLGIHEDYTLATRKLEAAATANTFPSANYF 120 L + +R+ L+GM E+ AL + +L+DLGI + ++ N + + Sbjct: 61 LMDHFRSQLSGMSMTELKALFILPSDKVLKDLGIPTKGRDIRLNMLSSLQGNRKHAVRPY 120 Query: 121 NQRIHIDSEGWVPSKESFPFLSELQTALWEDRKVNISYLR-NGEVKNRKIGLLGLVAKQG 179 ++++ID+ W PSKE + +Q A++E++K+ I Y GE + R I LGLVAK Sbjct: 121 LEKVYIDTGTWKPSKERMEEFNVVQQAVFEEKKLYIVYENAKGEQRERLISPLGLVAKGS 180 Query: 180 VWYVIGE-HDGQFRTYRVSRIIACQKIDEAYTRPDDFELTSYWESSKVSFKSALPSYKAK 238 WYV+ G R +++SRI + + E +P+ F L +YW SK F LPSY+A Sbjct: 181 AWYVVATVETGDIRNFKLSRIKDSKLVREPIVKPETFSLATYWNESKEQFVQTLPSYEAT 240 Query: 239 -FXXXXXXXXXXXXERYVTVLSMEDSPGSAWLKVEAEFNTIEAACRVMLSLGPNVIVGEP 297 ++V + + W+ V F+ + +L G + + P Sbjct: 241 VLAHDSIIHRLTFTGKFVENIQV-GHRDDEWVTVNLCFHDEQEITEYVLGFGGRMKLVTP 299 Query: 298 EELRARVYKAA 308 + L R+ + A Sbjct: 300 KHLIGRIVQQA 310 >lin0464 [K] COG2378 Predicted transcriptional regulator Length = 310 Score = 78.6 bits (192), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 58/222 (26%), Positives = 103/222 (46%), Gaps = 17/222 (7%) Query: 1 MRADRXXXXXXXXQNRGKVTSRELAGTLEVSERTIFRDMEALSASGIPVLAERGREGGWM 60 M+ DR ++ +++++ELA EVS RTI+RD++A+ +G+P+ + G GG+ Sbjct: 1 MKVDRLMSIVLILLDKERISAQELADRFEVSLRTIYRDIDAIDLAGVPIRSTPGVGGGFE 60 Query: 61 LTEGYRTSLTGMKPKEIGALQLSADPSILQDLGIHEDYTLATRKLEAAATANTFPSANYF 120 + Y+ M K LSA IL L + + A A +F A+ Sbjct: 61 IMPDYK-----MDSKVFSTADLSA---ILMGLSSLSNMVRGDELINALAKIKSFIPADRA 112 Query: 121 NQ------RIHIDSEGWVPSKESFPFLSELQTALWEDRKVNISYL-RNGEVKNRKIGLLG 173 + +I+ID W + P + ++ AL E++ + Y+ G R + Sbjct: 113 KEIELKANQIYIDLSQWTGNNNIQPHVEIIKVALQENKLLTFEYIAHQGNKTVRIVEPYQ 172 Query: 174 LVAKQGVWYVIG--EHDGQFRTYRVSRIIACQKIDEAYTRPD 213 LV K WY+ G ++ FR +R+SR+ Q +++ +T D Sbjct: 173 LVMKSSHWYLYGYCQNRNDFRLFRLSRMSGLQILEDTFTLRD 214 >lin0395 [K] COG2378 Predicted transcriptional regulator Length = 306 Score = 64.7 bits (156), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 57/217 (26%), Positives = 96/217 (44%), Gaps = 12/217 (5%) Query: 1 MRADRXXXXXXXXQNRGKVTSRELAGTLEVSERTIFRDMEALSASGIPVLAERGREGGWM 60 M+ +R R V++ E+A EVS+RTIFRD++ LS + IP+ G +GG Sbjct: 1 MKIERLIGIIMLLLQRELVSASEMATMFEVSKRTIFRDIDTLSMANIPIYTIAGTKGGIG 60 Query: 61 LTEGYRTSLTGMKPKEIGALQLSADPSILQDLGIHEDYTLATRKLEAAATANTFP-SANY 119 + Y+ + ++ A+ S D G+ + + A K N S+ Sbjct: 61 IMPTYKVDKKLLTADDLTAIIASLD-------GMEQLLSSAETKKTLQKMKNMLEHSSEP 113 Query: 120 FNQRIHIDSEGWVPSKESFPFLSELQTALWEDRKVNISYL-RNGEVKNRKIGLLGLVAKQ 178 I +D KE + L A+ + + V +SY+ R G RK L+ + Sbjct: 114 PKSSISLDFSNLSMKKELNAKVESLYLAIKKHQLVELSYIDRTGNQTVRKTEPYHLLFRN 173 Query: 179 GVWYVIGE--HDGQFRTYRVSRIIACQKIDEAY-TRP 212 WY+ G FRT+++SRI+ + ++E + RP Sbjct: 174 RSWYLQGYSLERSDFRTFKMSRIVELKTLEETFEARP 210 >lin2535 [K] COG2378 Predicted transcriptional regulator Length = 298 Score = 57.4 bits (137), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 52/200 (26%), Positives = 92/200 (46%), Gaps = 28/200 (14%) Query: 18 KVTSRELAGTLEVSERTIFRDMEALSASGIPVLAERGREGGWMLTEGYRTSLTGMKPKEI 77 KV + ELA EVS RTI+RDM+ L +G PV+A G+ GG+ + + Y+ + +E Sbjct: 17 KVLASELAEKFEVSTRTIYRDMDTLLYAGFPVVALPGKNGGFTMLDTYKLATFTFSEEEK 76 Query: 78 GALQLSADPSILQDLGIHEDYTL----ATRKLEAAATANTFPSANYF------NQRIHID 127 L L+ L ++ L T + + P++NY R I+ Sbjct: 77 RIL--------LEALEARSEFMLNDSQETLREKITLLQTEKPTSNYIFFDSATQHRKQIE 128 Query: 128 SEGWVPSKESFPFLSELQTALWEDRKVNISYL-RNGEVKNRKIGLLGLVAKQGVWYV--I 184 +E V K ++ +Q A ++++I+Y+ +G NR+I L G WY+ Sbjct: 129 AE--VKRKIAY-----IQKAFTMKKQLDITYIAMDGTETNREISPQKLNLMDGSWYLEAY 181 Query: 185 GEHDGQFRTYRVSRIIACQK 204 R ++++RI + ++ Sbjct: 182 CHKRAAIRHFKLTRITSLKE 201 >lin0383 [K] COG2378 Predicted transcriptional regulator Length = 315 Score = 50.8 bits (120), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 47/218 (21%), Positives = 84/218 (38%), Gaps = 26/218 (11%) Query: 2 RADRXXXXXXXXQNRGKVTSRELAGTLEVSERTIFRDMEALSASGIPVLAERGREGGWML 61 +++R ++ E+ VS T RD+++L G+P+ +ERGR G + + Sbjct: 3 KSERLNDMMLFLNDKNTFQLSEIMAKYGVSRSTAIRDIKSLEEIGMPIYSERGRNGHYQV 62 Query: 62 TEGYRTSLTGMKPKEIGALQLS--------ADPSIL--QDLGIHEDYTLATRKLEAA-AT 110 S E+ AL S P L + L ++ L+ K+E T Sbjct: 63 LRNRLLSPIVFNIDEVFALYFSMLTLKAYETTPFHLSVEKLKTKFEHCLSAEKIEMLRKT 122 Query: 111 ANTFPSANYFNQRIHIDSEGWVPSKESFPFLSELQTALWEDRKVNISYLRNGEVKNRKIG 170 F S G++ FL + E++ I+Y +NG K + Sbjct: 123 EEVF-------------SLGYIKHNNQCEFLDIILQFTMEEKVCQINYDKNGTEKTYIVQ 169 Query: 171 LLGLVAKQGVWYVIGEH--DGQFRTYRVSRIIACQKID 206 + + G WYV + D + + +R RI+ ++ D Sbjct: 170 FYNISSAYGQWYVTSYNFKDKRMQVFRCDRILGLKESD 207 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.316 0.132 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 21,965,647 Number of extensions: 852436 Number of successful extensions: 2256 Number of sequences better than 1.0e-05: 6 Number of HSP's gapped: 2253 Number of HSP's successfully gapped: 6 Length of query: 331 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 224 Effective length of database: 26,037,693 Effective search space: 5832443232 Effective search space used: 5832443232 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 116 (49.3 bits)