BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0247.0004.p
         (197 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BH1608 [R] COG1266 Predicted metal-dependent membrane protease        108   4e-24
BS_ypbD [R] COG1266 Predicted metal-dependent membrane protease        92   4e-19

>BH1608 [R] COG1266 Predicted metal-dependent membrane protease
          Length = 198

 Score =  108 bits (271), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 69/179 (38%), Positives = 100/179 (55%), Gaps = 4/179 (2%)

Query: 17  QQLTDKILLLNLYITQGLTLFIGLI---WILLQKRNPIHILNFPDSAQFVYWALGLAAIM 73
           +Q+TD+ LL+NLY++Q   L I  I   W        I IL F     FV    G A ++
Sbjct: 9   KQMTDRELLINLYLSQTSMLVIAFILGWWWFGSWDAYIDILRFEPFNIFVLGG-GAAVLV 67

Query: 74  LIVDFLLTHIVPEDSMDDGGINELLFGKRPLWHILVIAAIVSVCEELLFRGAVQHTFGLY 133
           + VD +L   VP++ MDDGGINE +F  R  +HI  ++ +V+V EE LFRG +Q   GL 
Sbjct: 68  VTVDIVLYRYVPKEWMDDGGINERVFRNRSTFHIAFLSLVVAVAEETLFRGIIQQQLGLV 127

Query: 134 WTSILFAVIHVRYLRHWIPTGWVFLSSYGLGYIYIHSGTLWAPILCHFIIDVFSGLVIR 192
             S++FA++H RYL   I    +   S+ LG +++ +G L   I  HF ID   G+ +R
Sbjct: 128 IASLVFALVHFRYLHKPILFISIVAISFLLGVLFLVTGNLLVTIFAHFCIDFLLGIFLR 186


>BS_ypbD [R] COG1266 Predicted metal-dependent membrane protease
          Length = 189

 Score = 92.4 bits (228), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 47/134 (35%), Positives = 78/134 (58%)

Query: 61  QFVYWALGLAAIMLIVDFLLTHIVPEDSMDDGGINELLFGKRPLWHILVIAAIVSVCEEL 120
           + +++ + +A I+++ D  +    P    DDGGIN+ +F KR + HI+ +  +++  EE+
Sbjct: 34  RIIWYGVSIAVIVILADMAVMKWFPSHLYDDGGINKKIFSKRSIPHIIFLTLLIAFAEEM 93

Query: 121 LFRGAVQHTFGLYWTSILFAVIHVRYLRHWIPTGWVFLSSYGLGYIYIHSGTLWAPILCH 180
           LFRG +Q   GL+  S++FA +H RYL  W+    V   S+ LG +Y  +G L+ P+  H
Sbjct: 94  LFRGVLQTHIGLWTASLIFAALHFRYLSKWLLFIMVTAISFLLGLMYEWTGNLFVPMTAH 153

Query: 181 FIIDVFSGLVIRYR 194
           FIID      IR+ 
Sbjct: 154 FIIDAVFACQIRFE 167


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.332    0.148    0.490 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 14,722,524
Number of extensions: 658061
Number of successful extensions: 1251
Number of sequences better than 1.0e-05: 3
Number of HSP's gapped: 1255
Number of HSP's successfully gapped: 3
Length of query: 197
Length of database: 38,378,431
Length adjustment: 101
Effective length of query: 96
Effective length of database: 26,729,697
Effective search space: 2566050912
Effective search space used: 2566050912
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 113 (48.1 bits)