BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0244.0010.p (247 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0289 [TK] COG0745 Response regulators consisting of a CheY-li... 177 1e-44 SA0017 [TK] COG0745 Response regulators consisting of a CheY-lik... 171 1e-42 STM1655 [LKJ] COG0513 Superfamily II DNA and RNA helicases 170 2e-42 TM1655 [TK] COG0745 Response regulators consisting of a CheY-lik... 170 2e-42 CAC0321 [TK] COG0745 Response regulators consisting of a CheY-li... 169 3e-42 >CAC0289 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 235 Score = 177 bits (450), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 93/231 (40%), Positives = 139/231 (60%), Gaps = 5/231 (2%) Query: 10 KILLVDDEKGILTLLEITLKKERYHNISSCTTGEQALFFIKNHTYDLILLDVMLGDANGF 69 KILLVDDE+ IL LL LKKE + N+ + T G + + + ++I+LD+ML D +GF Sbjct: 8 KILLVDDEESILKLLTTVLKKEGFSNVITSTNGMDGVKKCRENAPEIIILDIMLPDIDGF 67 Query: 70 ELCREIRKHTDTPIFFITSCASDFDKLTGLGIGGDDYITKPFNPLEVIARIKALFRRQSL 129 E+ R+IR + PI F+++ + D DK+ GLG+G DDYITKPF+P EV R+KA +R + Sbjct: 68 EVFRQIRNFSSVPIMFLSAKSEDTDKIIGLGLGADDYITKPFSPKEVALRVKAHLKRIEM 127 Query: 130 TQASSSGNPEGAGNKEYNYGRFILRPADASLIVNGESVECTAKELELLSFFCRNPNRIYT 189 + S + N E E+ F + +I N +S AKEL LL + N N I + Sbjct: 128 VKKSLT-NRENIIKTEH----FTIDFEKGEIIKNDKSTILRAKELLLLKYLVENKNIILS 182 Query: 190 TSQIYELVWGSPGYGYEKTVTIHISKIRKKLDDNPKAPELIINLRGIGYKF 240 +I VW GY+ T+ +HI K+R+KL+D+P P+ I+ ++G+GYK Sbjct: 183 KEKIVNAVWEDDYVGYDNTIMVHIRKLRQKLEDDPSNPKYILTVKGLGYKL 233 >SA0017 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 235 Score = 171 bits (432), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 87/231 (37%), Positives = 134/231 (58%), Gaps = 5/231 (2%) Query: 8 AEKILLVDDEKGILTLLEITLKKERYHNISSCTTGEQALFFIKNHTYDLILLDVMLGDAN 67 A K+++VDDEK I +LE LKKE Y ++ G A+ I D++LLD+ML + Sbjct: 4 ARKVVVVDDEKPIADILEFNLKKEGY-DVYCAYDGNDAVDLIYEEEPDIVLLDIMLPGRD 62 Query: 68 GFELCREIRKHTDTPIFFITSCASDFDKLTGLGIGGDDYITKPFNPLEVIARIKALFRRQ 127 G E+CRE+RK + PI +T+ S+ DK+ GL +G DDY+TKPF+ E+IAR+KA RR Sbjct: 63 GMEVCREVRKKYEMPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLRRH 122 Query: 128 SLTQASSSGNPEGAGNKEYNYGRFILRPADASLIVNGESVECTAKELELLSFFCRNPNRI 187 A +GN E ++ P S+ GE +E T +E EL + ++ ++ Sbjct: 123 YSQPAQDTGNV----TNEITIKDIVIYPDAYSIKKRGEDIELTHREFELFHYLSKHMGQV 178 Query: 188 YTTSQIYELVWGSPGYGYEKTVTIHISKIRKKLDDNPKAPELIINLRGIGY 238 T + + VWG +G +TV + I ++R+K++D+P PE I+ RG+GY Sbjct: 179 MTREHLLQTVWGYDYFGDVRTVDVTIRRLREKIEDDPSHPEYIVTRRGVGY 229 >STM1655 [LKJ] COG0513 Superfamily II DNA and RNA helicases Length = 457 Score = 170 bits (431), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 17/243 (6%), Positives = 44/243 (18%), Gaps = 13/243 (5%) Query: 9 EKILLVDDEKGILTLLEITLKKERYHNISSCTTGEQALFFIKNHTYDLILLDVMLGDANG 68 L E G L + + ++ QA + L + Sbjct: 12 AAQLNNLTELGYLEMTPVQAAALPVI-LAGNDVRVQARTGSGKTAAFGLGLLHRIDVTLF 70 Query: 69 FELCREIR---KHTDTPIFFITSCASDFDKLTGLGIGGDDYITKPFNPLEVIARIKALFR 125 + + D + A L + G + L+ I Sbjct: 71 QTQALVLCPTRELADQVAGELRRLARFLPNTKILTLCGGQPFGAQRDSLQHAPHIIVATP 130 Query: 126 RQSLTQASSSGNPEG--AGNKEYNYGRFILRPADASLIVNGESVECTAKELELLSFFCRN 183 + L R + ++++ + Sbjct: 131 GRLLDHLQKETVSLDALHILVMDEADRMLDM-------GFSDAIDEVIRFAPATRQTLLF 183 Query: 184 PNRIYTTSQIYELVWGSPGYGYEKTVTIHISKIRKKLDDNPKAPELIINLRGIGYKFVPP 243 E + I ++ + ++ + + Sbjct: 184 SATWPEAIAAISGRVQQQPIRIEIDTVDALPAIEQQFFETSAHEKISLLQTLLSQHQPAS 243 Query: 244 VKE 246 Sbjct: 244 CVV 246 >TM1655 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 247 Score = 170 bits (431), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 92/243 (37%), Positives = 144/243 (59%), Gaps = 13/243 (5%) Query: 9 EKILLVDDEKGILTLLEITLKKERYHNISSCTTGEQALFFIKNHTYDLILLDVMLGDANG 68 +KIL+VDD+ IL L+ L KE Y + GE+AL + D+ ++D+ML +G Sbjct: 12 KKILVVDDDPAILELVGYNLSKEGYE-VLKAYDGEEALKIANDEDVDMFIVDIMLPGIDG 70 Query: 69 FELCREIR---KHTDTPIFFITSCASDFDKLTGLGIGGDDYITKPFNPLEVIARIKALFR 125 FEL R+IR K+ +TP+ F+++ +FDK+ GL +G DDYITKPF+ E++AR+KA+FR Sbjct: 71 FELVRKIRSMEKYKNTPVIFLSAKGEEFDKVLGLELGADDYITKPFSVRELLARVKAIFR 130 Query: 126 RQSLTQASSSGNPEG--AGNKEYNYGRFILRPADASLIVNGESVECTAKELELLSFFCRN 183 R S S P+ A + E + ++ ++ V G+ V T E ELL F N Sbjct: 131 RLSTATQSKEERPKKIIAKDLEIDVEKYEVK-------VRGKKVNLTPLEFELLRFLAEN 183 Query: 184 PNRIYTTSQIYELVWGSPGYGYEKTVTIHISKIRKKLDDNPKAPELIINLRGIGYKFVPP 243 ++++ + + +WG YG +TV +HI ++R K++++P P+ II +RG GYKF P Sbjct: 184 EGKVFSRDVLLDKLWGYDYYGDTRTVDVHIRRLRTKIEEDPSNPKYIITVRGKGYKFRDP 243 Query: 244 VKE 246 KE Sbjct: 244 GKE 246 >CAC0321 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 230 Score = 169 bits (428), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 86/232 (37%), Positives = 140/232 (60%), Gaps = 5/232 (2%) Query: 9 EKILLVDDEKGILTLLEITLKKERYHNISSCTTGEQALFFIKNHTYDLILLDVMLGDANG 68 +KIL+++DE I L + L+ + + +G+ L K Y+LI+LD+ML + +G Sbjct: 2 KKILIIEDETSIAELEKDYLELSNFK-VDIEVSGKTGLEAAKEKNYELIILDLMLPEIDG 60 Query: 69 FELCREIRKHTDTPIFFITSCASDFDKLTGLGIGGDDYITKPFNPLEVIARIKALFRRQS 128 FE+C++IRK +TPI +++ D DK+ GLG+G DDY+TKPF+P E++AR+KA R Sbjct: 61 FEICKQIRKIKNTPILMVSAKKEDIDKIRGLGLGADDYMTKPFSPSELVARVKAHISRYE 120 Query: 129 LTQASSSGNPEGAGNKEYNYGRFILRPADASLIVNGESVECTAKELELLSFFCRNPNRIY 188 SS+ N + E + A + VNG+ + TAKE +LL F +NP+R++ Sbjct: 121 RLVNSSNKNL----DDEIEIRGLNINKASRKVFVNGKESQFTAKEFDLLVFLAQNPDRVF 176 Query: 189 TTSQIYELVWGSPGYGYEKTVTIHISKIRKKLDDNPKAPELIINLRGIGYKF 240 + ++++ +WG +G TVT+HI KIR+K++ + PE I + G GY+F Sbjct: 177 SKEELFDKIWGMDSFGEIATVTVHIKKIREKIEKDTSNPEYIETVWGAGYRF 228 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.139 0.411 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 18,997,008 Number of extensions: 741898 Number of successful extensions: 2320 Number of sequences better than 1.0e-05: 352 Number of HSP's gapped: 1999 Number of HSP's successfully gapped: 352 Length of query: 247 Length of database: 38,378,431 Length adjustment: 104 Effective length of query: 143 Effective length of database: 26,383,695 Effective search space: 3772868385 Effective search space used: 3772868385 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 114 (48.5 bits)