BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0244.0002.p
         (321 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

alr3751 [H] COG0276 Protoheme ferro-lyase (ferrochelatase)            110   4e-24

>alr3751 [H] COG0276 Protoheme ferro-lyase (ferrochelatase)
          Length = 346

 Score =  110 bits (274), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 18/340 (5%), Positives = 44/340 (12%), Gaps = 35/340 (10%)

Query: 7   KIGVLVMSYGTPESLEGVEAYYTHI-----------RRGHAP-----SPEQLKELKDRYE 50
              +   S        G   +                          +       +   +
Sbjct: 3   YHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQ 62

Query: 51  AIVGGVFPLRENTNRQVEALQAALNNGHAGEKVEFVCYQGLKHARPFIEDGVEAMAKDGI 110
            +                      +                      ++      A    
Sbjct: 63  GLTETY-VGNWLAKHGSREKLIIAS--KVSGPSR--NNDKGIRPDQALDRKNIREALHDS 117

Query: 111 THGVGIVLAPHYSVMSVGTYIKRA----KEKAEASGIEMAFVESYHLHPELIEVLSRRVS 166
              +       Y V                  +++           L         R + 
Sbjct: 118 LKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIG 177

Query: 167 AKLDLFEEAGAVREDVRVLFSAHSLPERILS-MGDPYRDQLLATSEAVAKQAGVRNWQ-F 224
              +              L   H LP  +         ++      A   Q        +
Sbjct: 178 VSNETAFGV----MRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAY 233

Query: 225 TWQSAGRTAEPWLGPDILETLHELSEAQVKYVLVAPVGFVSDHLEVLYDLDIEAQALASE 284
           +    G                  +               +    V              
Sbjct: 234 SCLGFGTLTG-KYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMA 292

Query: 285 LDM-RLMRIDSLNSDPAYMSVLSDVVRTAAGQ--FKVSQS 321
           L   R     +     A           +      +   +
Sbjct: 293 LAFVRRQPFVASTLLGATTMDQLKTNIESLHLELSEDVLA 332


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.317    0.132    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 22,814,296
Number of extensions: 978398
Number of successful extensions: 2255
Number of sequences better than 1.0e-05: 1
Number of HSP's gapped: 2253
Number of HSP's successfully gapped: 1
Length of query: 321
Length of database: 38,378,431
Length adjustment: 106
Effective length of query: 215
Effective length of database: 26,153,027
Effective search space: 5622900805
Effective search space used: 5622900805
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 116 (49.3 bits)