BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0231.0085.p (707 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value all4225_2 [T] COG2200 FOG: EAL domain 271 2e-72 all1175_4 [T] COG2200 FOG: EAL domain 244 5e-64 all4897_4 [T] COG2200 FOG: EAL domain 239 1e-62 alr3170_3 [T] COG2200 FOG: EAL domain 239 2e-62 all0219_3 [T] COG2200 FOG: EAL domain 235 1e-61 >all4225_2 [T] COG2200 FOG: EAL domain Length = 260 Score = 271 bits (694), Expect = 2e-72, Method: Compositional matrix adjust. Identities = 130/248 (52%), Positives = 174/248 (70%), Gaps = 1/248 (0%) Query: 448 ERLKLENDLRRALERDEFYLVYQPQVQLETEEIVGMEALLRWNHPKRGLVSPVDFIPIAE 507 ERL LEN+L ALER+E + YQP + L+T++I +EAL+RW HP RGLVSP FIPIAE Sbjct: 1 ERLALENELHGALERNEIVVYYQPIIDLQTKQITAVEALVRWQHPTRGLVSPAKFIPIAE 60 Query: 508 ESGLIVPIGEWVLKTACLQNKMWQNAGYRPICVSINLSMRQFLQPNLAGKIDVILQDIGL 567 +GLIV IGEWVL+TACLQN+ WQ AG PI +S+NLS RQF + NL + I+Q+ GL Sbjct: 61 ANGLIVEIGEWVLRTACLQNRTWQLAGLPPIRMSVNLSARQFEESNLVELVSEIIQESGL 120 Query: 568 DPCYVDLEITE-SMTLDKETAFDQLNRLKRLGVFISIDDFGTGYSSLHYLKNMPIDRLKI 626 P Y++LE+TE S+ D + + L +L+ LGV++++DDFGTGYSSL+YLK P++ LKI Sbjct: 121 HPSYLELEVTESSLMTDIQRSVTILKQLRELGVWLALDDFGTGYSSLNYLKRFPVNMLKI 180 Query: 627 DRSFVSEVLEDSNNAAIVSTITSMAHHLKLKVTAEGVENXXXXXXXXXXXCHEGQGYLFS 686 DRSFV +V + ++AA+ + I ++A L+LK+TAEG+E C EGQGY F Sbjct: 181 DRSFVQDVCSNPDSAAVTNAIIALAKSLQLKITAEGIETQQQLSYLQKRGCQEGQGYYFG 240 Query: 687 KPIKAAEF 694 P A E Sbjct: 241 IPAPAKEI 248 >all1175_4 [T] COG2200 FOG: EAL domain Length = 261 Score = 244 bits (622), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 121/245 (49%), Positives = 163/245 (66%), Gaps = 1/245 (0%) Query: 448 ERLKLENDLRRALERDEFYLVYQPQVQLETEEIVGMEALLRWNHPKRGLVSPVDFIPIAE 507 E L LE LR ALE+ E + YQP+V + T +I GMEALLRW HP+ G+V+P FIPIAE Sbjct: 1 ELLTLEKSLRYALEKQELKVYYQPRVNILTGQITGMEALLRWQHPEMGIVAPSIFIPIAE 60 Query: 508 ESGLIVPIGEWVLKTACLQNKMWQNAGYRPICVSINLSMRQFLQPNLAGKIDVILQDIGL 567 E+GLI+PIGEWVL+TAC+QN+ WQ AG P+ +++NLS +QF QP L + IL + GL Sbjct: 61 ETGLIIPIGEWVLRTACMQNRAWQEAGLPPVQMAVNLSPKQFRQPTLLELVSAILAETGL 120 Query: 568 DPCYVDLEITESMTL-DKETAFDQLNRLKRLGVFISIDDFGTGYSSLHYLKNMPIDRLKI 626 P +++LEITES + D + L L+++GV I+IDDFGTG+SSL L+ +P+ LKI Sbjct: 121 APEFLELEITESTAIEDIDFTRSVLENLQQMGVDIAIDDFGTGHSSLSRLQLLPLHNLKI 180 Query: 627 DRSFVSEVLEDSNNAAIVSTITSMAHHLKLKVTAEGVENXXXXXXXXXXXCHEGQGYLFS 686 D SF+ + DS A IV I ++ L L++TAEGVE C + QG+LF Sbjct: 181 DGSFIKALTTDSKVAHIVKAIVTLGRSLGLRLTAEGVEKQEELDFLKSINCQDVQGFLFH 240 Query: 687 KPIKA 691 KP+ A Sbjct: 241 KPLSA 245 >all4897_4 [T] COG2200 FOG: EAL domain Length = 272 Score = 239 bits (610), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 123/261 (47%), Positives = 166/261 (63%), Gaps = 3/261 (1%) Query: 441 AMQMKAKERLKLENDLRRALERDEFYLVYQPQVQLETEEIVGMEALLRWNHPKRGLVSPV 500 +M +A + L+LE DLRRA+ER EF + YQP V LET +I+G EAL+RW HP+ GLVSP Sbjct: 3 SMYSQAAQLLQLEMDLRRAVERQEFQVHYQPIVSLETYKIIGFEALVRWQHPQHGLVSPE 62 Query: 501 DFIPIAEESGLIVPIGEWVLKTACLQNKMWQ--NAGYRPICVSINLSMRQFLQPNLAGKI 558 FI +AEE+GLIVPIG WVL+ AC Q + WQ + P+ +S+N+S +QF QPNL +I Sbjct: 63 RFISLAEETGLIVPIGYWVLREACRQMRAWQLEFTTHPPLTISVNISSKQFSQPNLIEEI 122 Query: 559 DVILQDIGLDPCYVDLEITESMTLDK-ETAFDQLNRLKRLGVFISIDDFGTGYSSLHYLK 617 ILQD GL+ + LEITE++ ++ E+A L +L+++ + + +DDFG GYSSL YL Sbjct: 123 RKILQDTGLEASSLKLEITETVLMENHESATAMLLQLQQMNIQLHLDDFGIGYSSLSYLH 182 Query: 618 NMPIDRLKIDRSFVSEVLEDSNNAAIVSTITSMAHHLKLKVTAEGVENXXXXXXXXXXXC 677 P LKIDRSFV + D N IV I S+A L + V AEGVE C Sbjct: 183 RFPSSALKIDRSFVINLGADEKNLEIVQAIISLALSLNIDVIAEGVETMEQLRQLQIKKC 242 Query: 678 HEGQGYLFSKPIKAAEFETFF 698 QGY+FS+P+ + +T Sbjct: 243 KHAQGYIFSQPLDSQSVDTLI 263 >alr3170_3 [T] COG2200 FOG: EAL domain Length = 260 Score = 239 bits (609), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 119/245 (48%), Positives = 162/245 (66%), Gaps = 3/245 (1%) Query: 450 LKLENDLRRALERDEFYLVYQPQVQLETEEIVGMEALLRWNHPKRGLVSPVDFIPIAEES 509 L+LE DLR A+ R E Y+VYQP V + T +I G EAL+RW HP+RGL+SPV+FIP+AEE+ Sbjct: 3 LQLETDLRWAIARQELYVVYQPIVSVATGKITGFEALVRWQHPERGLISPVEFIPVAEET 62 Query: 510 GLIVPIGEWVLKTACLQNKMW--QNAGYRPICVSINLSMRQFLQPNLAGKIDVILQDIGL 567 GLI+ IG++VL+ +C Q K W + ++ + +++NLS +QF QP L +I+ +LQ+ L Sbjct: 63 GLIIQIGQFVLRESCQQLKQWHLEFPEFQHLSINVNLSGKQFSQPYLVEEIEQLLQEFDL 122 Query: 568 DPCYVDLEITESMTLDKE-TAFDQLNRLKRLGVFISIDDFGTGYSSLHYLKNMPIDRLKI 626 DP + LEITES + A L +LK LG+ + IDDFGTGYSSL YL PID LKI Sbjct: 123 DPSSIKLEITESAIMASPGQAATILQQLKTLGIQLCIDDFGTGYSSLAYLHCFPIDILKI 182 Query: 627 DRSFVSEVLEDSNNAAIVSTITSMAHHLKLKVTAEGVENXXXXXXXXXXXCHEGQGYLFS 686 DRSF + DS AI+ I ++A +L++ V AEGVE C + QGYLFS Sbjct: 183 DRSFTKRIDSDSEQLAIIRAIVTLASNLEMSVVAEGVETVNQLVQLQLLKCDQAQGYLFS 242 Query: 687 KPIKA 691 KP+ + Sbjct: 243 KPLSS 247 >all0219_3 [T] COG2200 FOG: EAL domain Length = 266 Score = 235 bits (600), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 123/253 (48%), Positives = 164/253 (64%), Gaps = 9/253 (3%) Query: 448 ERLKLENDLRRALERDEFYLVYQPQVQLETEEIVGMEALLRWNHPKRGLVSPVDFIPIAE 507 ERL+LENDLRRA+ER EF + YQP V L T I G EAL+RW HP++G+V P +F+PIA+ Sbjct: 1 ERLQLENDLRRAIERHEFLVYYQPIVSLTTGRITGFEALVRWLHPEQGIVFPEEFMPIAQ 60 Query: 508 ESGLIVPIGEWVLKTACLQNKMWQ--------NAGYRPICVSINLSMRQFLQPNLAGKID 559 E+GLI+PI WVL+ AC Q + WQ + +P+ +SINL +F Q L I+ Sbjct: 61 ETGLIIPIDAWVLREACRQTRQWQEQIPSLSTDLHKQPLSISINLCSSRFSQKKLLEDIN 120 Query: 560 VILQDIGLDPCYVDLEITESMTLDK-ETAFDQLNRLKRLGVFISIDDFGTGYSSLHYLKN 618 +LQD GLD + LEITES+ ++ E A LN+L+ LG+ ++IDDFGTGYSSL L N Sbjct: 121 QVLQDTGLDAQSLKLEITESVIMENGENATTMLNQLRNLGIELAIDDFGTGYSSLGRLHN 180 Query: 619 MPIDRLKIDRSFVSEVLEDSNNAAIVSTITSMAHHLKLKVTAEGVENXXXXXXXXXXXCH 678 PI+ LKID+SFVS ++ N IV TI +++ L + VTAEGVE C Sbjct: 181 FPINGLKIDQSFVSGRGVEAGNLHIVETIVTLSSKLGVDVTAEGVETPAQLQRLRELKCE 240 Query: 679 EGQGYLFSKPIKA 691 GQGY FS+P+ + Sbjct: 241 YGQGYFFSEPLDS 253 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.323 0.139 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 46,641,728 Number of extensions: 1853565 Number of successful extensions: 4503 Number of sequences better than 1.0e-05: 251 Number of HSP's gapped: 4199 Number of HSP's successfully gapped: 252 Length of query: 707 Length of database: 38,378,431 Length adjustment: 113 Effective length of query: 594 Effective length of database: 25,345,689 Effective search space: 15055339266 Effective search space used: 15055339266 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 119 (50.4 bits)