BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0217.0003.p (237 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin2062 [TK] COG0745 Response regulators consisting of a CheY-li... 191 7e-49 SA1323 [TK] COG0745 Response regulators consisting of a CheY-lik... 191 8e-49 BS_resD [TK] COG0745 Response regulators consisting of a CheY-li... 182 3e-46 SA0017 [TK] COG0745 Response regulators consisting of a CheY-lik... 171 9e-43 lin2644 [TK] COG0745 Response regulators consisting of a CheY-li... 167 2e-41 >lin2062 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 238 Score = 191 bits (486), Expect = 7e-49, Method: Compositional matrix adjust. Identities = 98/235 (41%), Positives = 148/235 (62%), Gaps = 6/235 (2%) Query: 4 IVVVDDDLFILQLLSEYLRKEAYEVTSFSSGANLVEYVRSEEPECLILDIMMPGIDGLSL 63 ++VVDD+ I +LL YL +E Y + S G + + E ++LD+MMPG DG+ + Sbjct: 7 VLVVDDEDRIRRLLKMYLERENYRIEEASDGDQALNMALNNNYEVILLDLMMPGKDGIEV 66 Query: 64 LTELRSFTEIPIIMISARGEESDRIHGLELGCSDFLSKPFNPRELVGRVKAMLRLYRMGN 123 ELR + P++M++A+GEE++R+ G E+G D++ KPF+PRE+V RVKA+LR + Sbjct: 67 CRELREYKSTPVVMLTAKGEEANRVQGFEVGADDYIVKPFSPREVVLRVKAVLRRAKQ-- 124 Query: 124 GASGDSAAPIKPDHICHAGNLKIYADYRRVTVDGTDISLTSREFELLLFLASHIERPFGR 183 S + AA P I +LKI + RV VDG +I LT +E++LL +LA ++ F R Sbjct: 125 --SSEEAAGGTPGDIITFPHLKIDNEAHRVIVDGKEIGLTPKEYDLLYYLAKSPDKVFDR 182 Query: 184 EQLIQHVWNYDFFGDVRVVDDLVKRIRKKLAE--HGSTLLINTVWGFGYKAAVSK 236 E L++ VW Y+FFGD+R +D VKR+R+KL + + +I TVWG GYK V + Sbjct: 183 ESLLKEVWRYEFFGDLRTIDTHVKRLREKLHDVSEDAARMIVTVWGLGYKFEVPE 237 >SA1323 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 241 Score = 191 bits (485), Expect = 8e-49, Method: Compositional matrix adjust. Identities = 96/236 (40%), Positives = 148/236 (62%), Gaps = 6/236 (2%) Query: 2 GTIVVVDDDLFILQLLSEYLRKEAYEVTSFSSGANLVEYVRSEEPECLILDIMMPGIDGL 61 I++VDD+ I +LL YL +E++E+ S+G E C++LD+M+P +DG+ Sbjct: 3 NEILIVDDEDRIRRLLKMYLERESFEIHEASNGQEAYELAMENNYACILLDLMLPEMDGI 62 Query: 62 SLLTELRSFTEIPIIMISARGEESDRIHGLELGCSDFLSKPFNPRELVGRVKAMLRLYRM 121 + T+LR + PIIM++A+GEE++R+ G E G D++ KPF+PRE+V RVKA+L R Sbjct: 63 QVATKLREHKQTPIIMLTAKGEETNRVEGFESGADDYIVKPFSPREVVLRVKALL---RR 119 Query: 122 GNGASGDSAAPIKPDHICHAGNLKIYADYRRVTVDGTDISLTSREFELLLFLASHIERPF 181 + + + P D + +L+I D RV D +++LT +E+ELL++LA + F Sbjct: 120 TQSTTVEQSEPHARD-VIEFKHLEIDNDAHRVLADNQEVNLTPKEYELLIYLAKTPNKVF 178 Query: 182 GREQLIQHVWNYDFFGDVRVVDDLVKRIRKKLAEHGSTL--LINTVWGFGYKAAVS 235 REQL++ VW+Y+F+GD+R VD VKR+R+KL S +I TVWG GYK V Sbjct: 179 DREQLLKEVWHYEFYGDLRTVDTHVKRLREKLNRVSSEAAHMIQTVWGVGYKFEVK 234 >BS_resD [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 240 Score = 182 bits (463), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 97/233 (41%), Positives = 145/233 (62%), Gaps = 6/233 (2%) Query: 4 IVVVDDDLFILQLLSEYLRKEAYEVTSFSSGANLVEYVRSEEPECLILDIMMPGIDGLSL 63 I+VVDD+ I +LL YL +E Y + +G + + ++LD+MMPG DG+ + Sbjct: 9 ILVVDDEARIRRLLRMYLERENYAIDEAENGDEAIAKGLEANYDLILLDLMMPGTDGIEV 68 Query: 64 LTELRSFTEIPIIMISARGEESDRIHGLELGCSDFLSKPFNPRELVGRVKAMLRLYRMGN 123 ++R PIIM++A+GEE++R+ G E G D++ KPF+PRE+V RVKA+LR R Sbjct: 69 CRQIREKKATPIIMLTAKGEEANRVQGFEAGTDDYIVKPFSPREVVLRVKALLR--RASQ 126 Query: 124 GASGDSAAPIKPDHICHAGNLKIYADYRRVTVDGTDISLTSREFELLLFLASHIERPFGR 183 + ++ P K ++ +L I D RVT DGT++SLT + +ELL FLA ++ + R Sbjct: 127 TSYFNANTPTK--NVLVFSHLSIDHDAHRVTADGTEVSLTPKVYELLYFLAKTPDKVYDR 184 Query: 184 EQLIQHVWNYDFFGDVRVVDDLVKRIRKKLAEHG--STLLINTVWGFGYKAAV 234 E+L++ VW Y+FFGD+R VD VKR+R+KL + + I TVWG GYK V Sbjct: 185 EKLLKEVWQYEFFGDLRTVDTHVKRLREKLNKVSPEAAKKIVTVWGVGYKFEV 237 >SA0017 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 235 Score = 171 bits (433), Expect = 9e-43, Method: Compositional matrix adjust. Identities = 95/229 (41%), Positives = 138/229 (60%), Gaps = 8/229 (3%) Query: 4 IVVVDDDLFILQLLSEYLRKEAYEVTSFSSGANLVEYVRSEEPECLILDIMMPGIDGLSL 63 +VVVDD+ I +L L+KE Y+V G + V+ + EEP+ ++LDIM+PG DG+ + Sbjct: 7 VVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYEEEPDIVLLDIMLPGRDGMEV 66 Query: 64 LTELRSFTEIPIIMISARGEESDRIHGLELGCSDFLSKPFNPRELVGRVKAMLRL-YRMG 122 E+R E+PIIM++A+ E D++ GLELG D+++KPF+ REL+ RVKA LR Y Sbjct: 67 CREVRKKYEMPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLRRHYSQP 126 Query: 123 NGASGDSAAPIKPDHICHAGNLKIYADYRRVTVDGTDISLTSREFELLLFLASHIERPFG 182 +G+ I ++ IY D + G DI LT REFEL +L+ H+ + Sbjct: 127 AQDTGNVTNEIT------IKDIVIYPDAYSIKKRGEDIELTHREFELFHYLSKHMGQVMT 180 Query: 183 REQLIQHVWNYDFFGDVRVVDDLVKRIRKKLAEHGS-TLLINTVWGFGY 230 RE L+Q VW YD+FGDVR VD ++R+R+K+ + S I T G GY Sbjct: 181 REHLLQTVWGYDYFGDVRTVDVTIRRLREKIEDDPSHPEYIVTRRGVGY 229 >lin2644 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 236 Score = 167 bits (422), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 92/230 (40%), Positives = 138/230 (60%), Gaps = 4/230 (1%) Query: 4 IVVVDDDLFILQLLSEYLRKEAYEVTSFSSGANLVEYVRSEEPECLILDIMMPGIDGLSL 63 I+VVDD+ I+ LL + K ++V + G E SE+P+ ++LD+M+P +DG+ + Sbjct: 4 ILVVDDEASIVTLLQFNIEKAGFDVVTAEDGRTGYELALSEKPDLIVLDLMLPEMDGIEV 63 Query: 64 LTELRS-FTEIPIIMISARGEESDRIHGLELGCSDFLSKPFNPRELVGRVKAMLRLYRMG 122 +LR +PI+M++A+ EE D+I GLELG D+++KPF+PRE+V R+KA+LR R Sbjct: 64 TKKLRQDKVGVPILMLTAKDEELDKIIGLELGADDYMTKPFSPREVVARIKAILR--RTE 121 Query: 123 NGASGDSAAPIKPDHICHAGNLKIYADYRRVTVDGTDISLTSREFELLLFLASHIERPFG 182 A + G+LKI D V + + LT +EFELLLFLA+H + F Sbjct: 122 GKAEVTEEKTEDTEATILIGDLKILPDSYEVYLQDDLLDLTPKEFELLLFLANHRGKVFS 181 Query: 183 REQLIQHVWNYDFFGDVRVVDDLVKRIRKKLA-EHGSTLLINTVWGFGYK 231 R+QL+ VWNYD+ G+ R+VD V +R K+ + I T+ GFGYK Sbjct: 182 RDQLLDTVWNYDYVGETRIVDVHVSHLRDKIELDTKQPKYIKTIRGFGYK 231 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.323 0.141 0.413 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 17,409,663 Number of extensions: 667919 Number of successful extensions: 2478 Number of sequences better than 1.0e-05: 464 Number of HSP's gapped: 2075 Number of HSP's successfully gapped: 465 Length of query: 237 Length of database: 38,378,431 Length adjustment: 103 Effective length of query: 134 Effective length of database: 26,499,029 Effective search space: 3550869886 Effective search space used: 3550869886 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 114 (48.5 bits)