BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0212.0009.p (311 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH1544 [E] COG0019 Diaminopimelate decarboxylase 352 4e-97 SA1232 [E] COG0019 Diaminopimelate decarboxylase 275 9e-74 sll0504 [E] COG0019 Diaminopimelate decarboxylase 261 7e-70 Cgl1154 [E] COG0019 Diaminopimelate decarboxylase 246 4e-65 aq_1208 [E] COG0019 Diaminopimelate decarboxylase 152 7e-37 >BH1544 [E] COG0019 Diaminopimelate decarboxylase Length = 439 Score = 352 bits (904), Expect = 4e-97, Method: Compositional matrix adjust. Identities = 171/298 (57%), Positives = 213/298 (71%), Gaps = 1/298 (0%) Query: 2 ELHMLQAIALRKEVTVNILLRVTPGVEAHAHHAYASTGQTDSKFGFDIGNGXXXXXXXXX 61 EL +L I +K T NILLR+TPGVEAH H Y STGQ DSKFGFD+ +G Sbjct: 135 ELDLLADICEQKRATANILLRITPGVEAHTHD-YISTGQEDSKFGFDLVSGQATLAVKKA 193 Query: 62 XXQSNLQLLGVHSHIGSQIFETEGFELAVERIAGFTRKVKEELGVEFPVVNLGGGFGIRY 121 ++ LLGVHSHIGSQIFET GF +AVE+I +E+ G E V+NLGGGFGIRY Sbjct: 194 LAVDSIHLLGVHSHIGSQIFETTGFVMAVEKIFEHLVTWREDHGFEPSVLNLGGGFGIRY 253 Query: 122 VEGDTPLQVSEYVAAITGAVKTHFTGISEKLPQIWVEPGRSIVGDAGTTLYTVGTNKEIP 181 +EGDTP V +YV + AVK +P+IW+EPGRS+VGDAGTTLYT+G+ KEIP Sbjct: 254 IEGDTPRPVGDYVKEMIRAVKQQIAEHEMSMPEIWIEPGRSLVGDAGTTLYTIGSRKEIP 313 Query: 182 GVRKYVAVDGGMTDNPRPALYESKYEALLANRAAEPNEETVSIAGKCCESGDMLIWDVEL 241 VR Y++VDGGM+DN RPALY+++YE LANR E S+AGKCCESGDMLIWD+ L Sbjct: 314 NVRHYLSVDGGMSDNLRPALYQAEYEGALANRVNEQPVGMFSVAGKCCESGDMLIWDLPL 373 Query: 242 PKVESGDLLAVACTGAYNYSMASNYNRIRRPAVVFVQNGQSDLVVRRESHQDIIANDI 299 P+ D+LAV CTGAY YSMA+NYNRI RP VVFV++G + LV++RE ++D++ D+ Sbjct: 374 PEANHEDILAVFCTGAYGYSMANNYNRIPRPPVVFVEDGDAQLVIQRERYEDLVRLDM 431 >SA1232 [E] COG0019 Diaminopimelate decarboxylase Length = 421 Score = 275 bits (702), Expect = 9e-74, Method: Compositional matrix adjust. Identities = 141/284 (49%), Positives = 195/284 (68%), Gaps = 7/284 (2%) Query: 16 TVNILLRVTPGVEAHAHHAYASTGQTDSKFGFDIGNGXXXXXXXXXXXQSNLQLLGVHSH 75 TV ++LRV PGVEAH H + TGQ DSKFG I G +L+L GVH H Sbjct: 142 TVQVVLRVNPGVEAHTHE-FIQTGQEDSKFGLSIQYGLAKKAIDKVQQSKHLKLKGVHCH 200 Query: 76 IGSQIFETEGFELAVERIAGFTRKVKEELGVEFPVVNLGGGFGIRYVEGDTPLQVSEYVA 135 IGSQI TE F +E R +KE+ G++ ++NLGGGFGI+YVEGD + + Sbjct: 201 IGSQIEGTEAF---IETAKIVLRWLKEQ-GIQVELLNLGGGFGIKYVEGDESFPIESGIK 256 Query: 136 AITGAVKTHFTGISEKLPQIWVEPGRSIVGDAGTTLYTVGTNKEIPGVRKYVAVDGGMTD 195 IT A+K+ + P+I +EPGRSIVG+AG TLY VGT KEIP + KYV++DGGM+D Sbjct: 257 DITDAIKSEIKVLGIDAPEIGIEPGRSIVGEAGVTLYEVGTIKEIPEINKYVSIDGGMSD 316 Query: 196 NPRPALYESKYEALLANRAAEPNEETVSIAGKCCESGDMLIWDVELP-KVESGDLLAVAC 254 + R ALY++KY+ALL NR E + ++V+IAGK CESGD++I D +LP V+ GD LA+ Sbjct: 317 HIRTALYDAKYQALLVNRNEEAD-DSVTIAGKLCESGDIIIKDAKLPSSVKRGDYLAILS 375 Query: 255 TGAYNYSMASNYNRIRRPAVVFVQNGQSDLVVRRESHQDIIAND 298 TGAY+YSMASNYN++++P+V F+++G++ V++R+S + +I ND Sbjct: 376 TGAYHYSMASNYNQMQKPSVFFLKDGKAREVIKRQSLRQLIIND 419 >sll0504 [E] COG0019 Diaminopimelate decarboxylase Length = 469 Score = 261 bits (668), Expect = 7e-70, Method: Compositional matrix adjust. Identities = 140/307 (45%), Positives = 188/307 (61%), Gaps = 10/307 (3%) Query: 1 VELHMLQAIALRKEVTVNILLRVTPGVEAHAHHAYASTGQTDSKFGFDIGNGXXXXXXXX 60 +EL L +A V I+LR+TPG+E H H Y TG DSKFGFD Sbjct: 168 LELETLTKLAADSGAPVKIMLRLTPGIECHTHE-YIKTGHLDSKFGFD--PNQLEAVFTY 224 Query: 61 XXXQSNLQLLGVHSHIGSQIFETEGF-ELAVERIAGFTRKVKEELGVEFPVVNLGGGFGI 119 Q +L LG+H+HIGSQIFE + +L + FT+ + G+ +N+GGG GI Sbjct: 225 IAQQPSLHCLGLHAHIGSQIFERQPHKDLGEVLVQWFTKGLT--YGLPLTELNIGGGLGI 282 Query: 120 RYVEGDTPLQVSEY--VAAITGAVKTHFTGISEKLPQIWVEPGRSIVGDAGTTLYTVGTN 177 Y E D P + E+ VAAI+ A I P++ EPGRS+VG A T Y VG Sbjct: 283 CYTESDDPPSIEEWAQVAAISVAKACDRQNI--PYPKLIAEPGRSLVGSACVTAYRVGGR 340 Query: 178 KEIPGVRKYVAVDGGMTDNPRPALYESKYEALLANRAAEPNEETVSIAGKCCESGDMLIW 237 K +P +R Y++VDGGM+DNPRP Y+S Y LANR + ETV++AGK CESGD+L+ Sbjct: 341 KVVPNIRTYISVDGGMSDNPRPITYQSVYRVALANRMNDEITETVTVAGKHCESGDILVK 400 Query: 238 DVELPKVESGDLLAVACTGAYNYSMASNYNRIRRPAVVFVQNGQSDLVVRRESHQDIIAN 297 DV LP E GD++ VA TGAYN+SMASNYNR+ RPA V V GQ++L+++RE++ D++ Sbjct: 401 DVALPAAEPGDIMVVAATGAYNHSMASNYNRLGRPAAVLVNQGQANLILQRETYTDLLRQ 460 Query: 298 DIVPARI 304 D +P R+ Sbjct: 461 DCLPNRL 467 >Cgl1154 [E] COG0019 Diaminopimelate decarboxylase Length = 445 Score = 246 bits (627), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 131/300 (43%), Positives = 185/300 (61%), Gaps = 6/300 (2%) Query: 2 ELHMLQAIALRKEVTVNILLRVTPGVEAHAHHAYASTGQTDSKFGFDIGNGXXXXXXXXX 61 EL +L +A + ++L+RV PG+EAH H + +T D KFGF + +G Sbjct: 144 ELELLDYVAAGEGKIQDVLIRVKPGIEAHTHE-FIATSHEDQKFGFSLASGSAFEAAKAA 202 Query: 62 XXQSNLQLLGVHSHIGSQIFETEGFELAVERIAGFTRKVKEELGVEFPVVNLGGGFGIRY 121 NL L+G+H H+GSQ+F+ EGF+LA ER+ G ++ ELGV P ++LGGG+GI Y Sbjct: 203 NNAENLNLVGLHCHVGSQVFDAEGFKLAAERVLGLYSQIHSELGVALPELDLGGGYGIAY 262 Query: 122 VEGDTPLQVSEYVAAITGAVKTHFTGISEKLPQIWVEPGRSIVGDAGTTLYTVGTNKEI- 180 + PL V+E + + AV + P + VEPGR+I G + T+Y VGT K++ Sbjct: 263 TAAEEPLNVAEVASDLLTAVGKMAAELGIDAPTVLVEPGRAIAGPSTVTIYEVGTTKDVH 322 Query: 181 ---PGVRKYVAVDGGMTDNPRPALYESKYEALLANRAAEPNEETVSIAGKCCESGDMLIW 237 R+Y+AVDGGM+DN RPALY S+Y+A + +R AE + + I G CESGD+LI Sbjct: 323 VDDDKTRRYIAVDGGMSDNIRPALYGSEYDARVVSRFAEGDPVSTRIVGSHCESGDILIN 382 Query: 238 DVELPK-VESGDLLAVACTGAYNYSMASNYNRIRRPAVVFVQNGQSDLVVRRESHQDIIA 296 D P + SGD LA+A TGAY Y+M+S YN RPAVV V+ G S L++RRE+ DI++ Sbjct: 383 DEIYPSDITSGDFLALAATGAYCYAMSSRYNAFTRPAVVSVRAGSSRLMLRRETLDDILS 442 >aq_1208 [E] COG0019 Diaminopimelate decarboxylase Length = 420 Score = 152 bits (384), Expect = 7e-37, Method: Compositional matrix adjust. Identities = 98/297 (32%), Positives = 154/297 (51%), Gaps = 19/297 (6%) Query: 2 ELHMLQAIALRKEVTVNILLRVTPGVEAHAHHAYASTGQTDSKFGFDIGNGXXXXXXXXX 61 EL +L IA + I +RV P V+ H Y +TG SKFG DI Sbjct: 134 ELDVLNEIAGKLGKKARIAIRVNPDVDPKTH-PYIATGMQKSKFGVDIREAQKEYEYASK 192 Query: 62 XXQSNLQLLGVHSHIGSQIFETEGFELAVERIAGFTRKVKEELGVEFPVVNLGGGFGIRY 121 NL+++G+H HIGSQI + + AVE++ + ++ G + +++GGG GI+Y Sbjct: 193 L--ENLEIVGIHCHIGSQILDISPYREAVEKVVSLYESLTQK-GFDIKYLDIGGGLGIKY 249 Query: 122 VEGD---TPLQVSEYVAAITGAVKTHFTGISEKLPQIWVEPGRSIVGDAGTTLYTVGTNK 178 D P +++ + + VK +I +EPGRSI+G+AG + V K Sbjct: 250 KPEDKEPAPQDLADLLKDLLENVKA----------KIILEPGRSIMGNAGILITQVQFLK 299 Query: 179 EIPGVRKYVAVDGGMTDNPRPALYESKYEALLANRAAEPNEETVSIAGKCCESGDMLIWD 238 + G + ++ VD GM D RP++Y + Y ++ E + I G CE+GD L D Sbjct: 300 D-KGSKHFIIVDAGMNDLIRPSIYNA-YHHIIPVETKERKKVVADIVGPICETGDFLALD 357 Query: 239 VELPKVESGDLLAVACTGAYNYSMASNYNRIRRPAVVFVQNGQSDLVVRRESHQDII 295 E+ +V+ G+ LAV GAY ++M+S+YN R A V V+NG L+ +RE++ I+ Sbjct: 358 REIEEVQRGEYLAVLSAGAYGFAMSSHYNMRPRAAEVLVENGSVKLIRKRENYDYIV 414 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.135 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 22,991,601 Number of extensions: 1007798 Number of successful extensions: 1739 Number of sequences better than 1.0e-05: 37 Number of HSP's gapped: 1629 Number of HSP's successfully gapped: 37 Length of query: 311 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 205 Effective length of database: 26,153,027 Effective search space: 5361370535 Effective search space used: 5361370535 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 116 (49.3 bits)