BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0193.0007.p (224 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Cgl0399 [TK] COG0745 Response regulators consisting of a CheY-li... 148 8e-36 CC0294 [TK] COG0745 Response regulators consisting of a CheY-lik... 143 2e-34 MT0510 [TK] COG0745 Response regulators consisting of a CheY-lik... 143 2e-34 Rv0491 [TK] COG0745 Response regulators consisting of a CheY-lik... 142 3e-34 lin2062 [TK] COG0745 Response regulators consisting of a CheY-li... 142 3e-34 >Cgl0399 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 232 Score = 148 bits (373), Expect = 8e-36, Method: Compositional matrix adjust. Identities = 87/230 (37%), Positives = 130/230 (56%), Gaps = 12/230 (5%) Query: 1 MFNILVVEDDSKLRQLFCTVLTKNGYRAIPAVNGEDALTVLDKEYIDLIICDIMMPLMDG 60 M IL+VED+ L +L K G+ I A +G AL + ID+++ D+M+P M G Sbjct: 1 MTRILIVEDEESLADPLAFLLRKEGFDTIIAGDGPTALVEFSRNEIDIVLLDLMLPGMSG 60 Query: 61 YELTRTLRDXXXXLPVLMVTARETFADKQQGFLVGIDDYMVKPINVNEMLLRVGALLRRA 120 ++ + LR +PV+MVTAR++ DK G +G DDY+ KP + E++ R+ A+LRR Sbjct: 61 TDVCKELRSVST-VPVIMVTARDSEIDKVVGLELGADDYVTKPYSSRELIARIRAVLRRR 119 Query: 121 KI---------ISERRIEWGATILDYDALTVIQGQESILLPQKEFYLLYKLISYPNKIFT 171 + + ++ +E G +D D+ TV G E + +P KEF LL L+ ++ T Sbjct: 120 GVTETEAEELPLDDQILEGGRVRMDVDSHTVTVGGEPVSMPLKEFDLLEYLLRNAGRVLT 179 Query: 172 KQQLMDEIWGMDTESDEHTVVVHINRLRERFRE--STDFEIVTVRGLGYK 219 + QL+D IWG D D T+ VH+ RLR + E S +VTVRGLGYK Sbjct: 180 RGQLIDRIWGADYVGDTKTLDVHVKRLRSKIEEEPSRPRYLVTVRGLGYK 229 >CC0294 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 230 Score = 143 bits (360), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 87/220 (39%), Positives = 129/220 (58%), Gaps = 4/220 (1%) Query: 4 ILVVEDDSKLRQLFCTVLTKNGYRAIPAVNGEDALTVLDKEYIDLIICDIMMPLMDGYEL 63 +LVVED+ L L L K GYR A +GE+AL + ++ DL+I D M+P + G E+ Sbjct: 5 VLVVEDEDALATLLHYNLDKEGYRVGVAGDGEEALIMANERAPDLVILDWMLPKVSGIEV 64 Query: 64 TRTLRDXXXX--LPVLMVTARETFADKQQGFLVGIDDYMVKPINVNEMLLRVGALLRRAK 121 R LR +P++M+TAR D+ +G G DDY+VKP ++ E+ RV A+LRR + Sbjct: 65 CRRLRGRAETRNVPIIMLTARGEETDRIRGLDTGADDYVVKPFSMVELTARVRAVLRRIR 124 Query: 122 I-ISERRIEWGATILDYDALTVIQGQESILLPQKEFYLLYKLISYPNKIFTKQQLMDEIW 180 +++ RI G I+D A V + + I L EF LL L+ +P ++F+++QL+D +W Sbjct: 125 PGLADDRITVGDIIIDRVAHRVKRSGKEIHLGPTEFRLLDYLMQHPGRVFSREQLLDAVW 184 Query: 181 GMDTESDEHTVVVHINRLRERFRESTDFE-IVTVRGLGYK 219 G D + TV VHI RLR+ +TD + I TVR GY Sbjct: 185 GSDVYVEARTVDVHIGRLRKALNGTTDADPIRTVRSAGYS 224 >MT0510 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 230 Score = 143 bits (360), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 81/225 (36%), Positives = 126/225 (56%), Gaps = 7/225 (3%) Query: 1 MFNILVVEDDSKLRQLFCTVLTKNGYRAIPAVNGEDALTVLDKEYIDLIICDIMMPLMDG 60 M ++L+VED+ L +L K G+ A +G AL D+ D+++ D+M+P M G Sbjct: 4 MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG 63 Query: 61 YELTRTLRDXXXXLPVLMVTARETFADKQQGFLVGIDDYMVKPINVNEMLLRVGALLRRA 120 ++ + LR +PV+MVTAR++ DK G +G DDY+ KP + E++ R+ A+LRR Sbjct: 64 TDVCKQLR-ARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRG 122 Query: 121 ----KIISERRIEWGATILDYDALTVIQGQESILLPQKEFYLLYKLISYPNKIFTKQQLM 176 +S+ +E G +D + V ++I LP KEF LL L+ ++ T+ QL+ Sbjct: 123 GDDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLI 182 Query: 177 DEIWGMDTESDEHTVVVHINRLRERFRE--STDFEIVTVRGLGYK 219 D +WG D D T+ VH+ RLR + + +VTVRGLGYK Sbjct: 183 DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYK 227 >Rv0491 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 227 Score = 142 bits (359), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 81/225 (36%), Positives = 126/225 (56%), Gaps = 7/225 (3%) Query: 1 MFNILVVEDDSKLRQLFCTVLTKNGYRAIPAVNGEDALTVLDKEYIDLIICDIMMPLMDG 60 M ++L+VED+ L +L K G+ A +G AL D+ D+++ D+M+P M G Sbjct: 1 MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG 60 Query: 61 YELTRTLRDXXXXLPVLMVTARETFADKQQGFLVGIDDYMVKPINVNEMLLRVGALLRRA 120 ++ + LR +PV+MVTAR++ DK G +G DDY+ KP + E++ R+ A+LRR Sbjct: 61 TDVCKQLR-ARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRG 119 Query: 121 ----KIISERRIEWGATILDYDALTVIQGQESILLPQKEFYLLYKLISYPNKIFTKQQLM 176 +S+ +E G +D + V ++I LP KEF LL L+ ++ T+ QL+ Sbjct: 120 GDDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLI 179 Query: 177 DEIWGMDTESDEHTVVVHINRLRERFRE--STDFEIVTVRGLGYK 219 D +WG D D T+ VH+ RLR + + +VTVRGLGYK Sbjct: 180 DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYK 224 >lin2062 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 238 Score = 142 bits (359), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 88/227 (38%), Positives = 132/227 (58%), Gaps = 12/227 (5%) Query: 4 ILVVEDDSKLRQLFCTVLTKNGYRAIPAVNGEDALTVLDKEYIDLIICDIMMPLMDGYEL 63 +LVV+D+ ++R+L L + YR A +G+ AL + ++I+ D+MMP DG E+ Sbjct: 7 VLVVDDEDRIRRLLKMYLERENYRIEEASDGDQALNMALNNNYEVILLDLMMPGKDGIEV 66 Query: 64 TRTLRDXXXXLPVLMVTARETFADKQQGFLVGIDDYMVKPINVNEMLLRVGALLRRAKII 123 R LR+ PV+M+TA+ A++ QGF VG DDY+VKP + E++LRV A+LRRAK Sbjct: 67 CRELREYKST-PVVMLTAKGEEANRVQGFEVGADDYIVKPFSPREVVLRVKAVLRRAKQS 125 Query: 124 SERR--------IEWGATILDYDALTVIQGQESILLPQKEFYLLYKLISYPNKIFTKQQL 175 SE I + +D +A VI + I L KE+ LLY L P+K+F ++ L Sbjct: 126 SEEAAGGTPGDIITFPHLKIDNEAHRVIVDGKEIGLTPKEYDLLYYLAKSPDKVFDRESL 185 Query: 176 MDEIWGMDTESDEHTVVVHINRLRERFRESTDFE---IVTVRGLGYK 219 + E+W + D T+ H+ RLRE+ + ++ IVTV GLGYK Sbjct: 186 LKEVWRYEFFGDLRTIDTHVKRLREKLHDVSEDAARMIVTVWGLGYK 232 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.324 0.142 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 15,175,468 Number of extensions: 573267 Number of successful extensions: 3381 Number of sequences better than 1.0e-05: 435 Number of HSP's gapped: 3024 Number of HSP's successfully gapped: 435 Length of query: 224 Length of database: 38,378,431 Length adjustment: 103 Effective length of query: 121 Effective length of database: 26,499,029 Effective search space: 3206382509 Effective search space used: 3206382509 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 114 (48.5 bits)