BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0190.0005.p
         (592 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

MA0247 [R] COG2304 Uncharacterized protein containing a von Will...    70   1e-11

>MA0247 [R] COG2304 Uncharacterized protein containing a von Willebrand
           factor type A (vWA) domain
          Length = 589

 Score = 70.1 bits (170), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 54/193 (27%), Positives = 89/193 (46%), Gaps = 27/193 (13%)

Query: 33  IDAVLLIDVSNSMNKSDKNNIAGEAMKMFIDMLSAQGDKVGIVAYTDKVQREKALLQIGS 92
           +D V  ID S SM  +D + +   A K F+D + +  D  G+V++ D +     L     
Sbjct: 81  MDVVFAIDSSGSMQSNDPSGLRKTAAKSFVDKMDSSRDTAGVVSWDDSIDFSLPLTN--- 137

Query: 93  AADKQDLKDFIDGLDRGAYTDIAVGMEEAVKVLENGSDPGHE---PMIVMLADGNNDLNE 149
             D   +K  ID +D    T++ VG+EEA+ +L+  ++P  E    +I+ L DG      
Sbjct: 138 --DFPLVKTNIDSVDSSGSTNLNVGLEEAIDILD--ANPRTENSVEVIIFLTDGQGTY-- 191

Query: 150 ATGRTQSQSDQELDAAVETAKQKGYPVYTIGLNADGKLNKEILAGLSNKTSGKAFITDSA 209
                       L +  + A  KGY +Y+IGL   G +N   L  ++  T G  + +  A
Sbjct: 192 ------------LHSTAQEAADKGYVIYSIGL---GGVNPTPLQDMATTTGGAYYSSPDA 236

Query: 210 DDLPQILSEIFAD 222
             L  I  +IF++
Sbjct: 237 TSLQAIFDDIFSE 249


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.312    0.131    0.352 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 39,373,945
Number of extensions: 1602642
Number of successful extensions: 4063
Number of sequences better than 1.0e-05: 1
Number of HSP's gapped: 4064
Number of HSP's successfully gapped: 1
Length of query: 592
Length of database: 38,378,431
Length adjustment: 112
Effective length of query: 480
Effective length of database: 25,461,023
Effective search space: 12221291040
Effective search space used: 12221291040
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 119 (50.4 bits)