BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0188.0058.p (221 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM1494 [E] COG1174 ABC-type proline/glycine betaine transport s... 211 7e-55 MTH812 [S] COG4066 Uncharacterized protein conserved in archaea 72 5e-13 MTH87_2 [R] COG3291 FOG: PKD repeat 72 5e-13 MTH864 [K] COG0640 Predicted transcriptional regulators 72 5e-13 MTH855_1 [S] COG1900 Uncharacterized conserved protein 72 5e-13 >STM1494 [E] COG1174 ABC-type proline/glycine betaine transport systems, permease component Length = 236 Score = 211 bits (537), Expect = 7e-55, Method: Compositional matrix adjust. Identities = 19/207 (9%), Positives = 40/207 (19%), Gaps = 2/207 (0%) Query: 1 VGQKVNPVGLRIGIIRDWESKWYAGKDFGTLLMEDVKIREYLKGKLKDSSVSRIEIERA- 59 + L I+ + L YL + + + Sbjct: 1 MHTLTLKRVLGFTIVILLLLALFIWGIGLETLKARQVDLLYLGQRHLMLVFTSMFFALLV 60 Query: 60 ASRVNVTIHTAKPGMVIGKGGAEVEVLRSAVTTIAGGKKVHININEIKHPELDAILVAES 119 + + V + A + I P + A+ +A Sbjct: 61 GIPSGILLSRPAAKGFAEYVMQIFNVGNTLPPL-AVLALAMVIIGIGDTPAIVALFLASL 119 Query: 120 IAQQLERRVSFRRALKQAIQRTMRSGAKGIKTQVGGRLGGAEIARSEGYSEGTVPLHTLR 179 + I+ G + L A G T Sbjct: 120 LPIVRNTYAGLCSVPASLIEAANGIGMTKWQRLRQVELPNAWPVMLSGIRIATAINVGTA 179 Query: 180 ADIDYGTAEAHTTYGRIGVKVWIYRGE 206 A ++ G+ + + Sbjct: 180 PLAFLIGASSYGELIFPGIYLNDFPTL 206 >MTH812 [S] COG4066 Uncharacterized protein conserved in archaea Length = 214 Score = 72.4 bits (176), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 7/192 (3%), Positives = 25/192 (13%), Gaps = 9/192 (4%) Query: 26 KDFGTLLMEDVKIREYLKGKLKDSSVSRIEIERAASRVNVTIHTAKPGMVIGKGGAEVEV 85 G + + S + VN+ + + Sbjct: 4 AFMGAYCYYHQQTEWARELGQAIISEKLDSLLDGNGTVNLEGLDDSIKKAYIGLVISMYI 63 Query: 86 LRSAVTTIAGGKKVHININEIKHPELDAILVAESIAQQLERRVSFRRALKQAIQRTMRSG 145 + I + + + ++ + + Sbjct: 64 ALEGPMAFVDILNYALVEGFIGLNMAAYATIIAYTSLLNITDDIKKFIIEHQTYISEDTA 123 Query: 146 AKGIKTQVGGRLGGAEIAR---SEGYSE--GTVPLHTLRADIDYGTAEAHTTYGRIGVKV 200 I+ + G + Sbjct: 124 HCLIQVLAYVLVRYGGEIFQPIGWCMRIGDGILTFRDHYL----PQEYWKYISIHRTWIY 179 Query: 201 WIYRGEVLPPAK 212 + Sbjct: 180 GYELRSYVGEDH 191 >MTH87_2 [R] COG3291 FOG: PKD repeat Length = 673 Score = 72.4 bits (176), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 18/192 (9%), Positives = 41/192 (21%), Gaps = 9/192 (4%) Query: 26 KDFGTLLMEDVKIREYLKGKLKDSSVSRIEIERAASRVNVTIHTAKPGMVIGKGGAEVEV 85 +E V + I + A V A E+ Sbjct: 4 NPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREM 63 Query: 86 LRSAVTTIAGGKKVHININEIKHPELDAILVAESIAQQLERRVSFRRALKQAIQRTMRSG 145 T+ + + I+ LD I + F + A+ + + G Sbjct: 64 KERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTEG 123 Query: 146 AKGIKTQVGGRLGGAEIAR---SEGYSE--GTVPLHTLRADIDYGTAEAHTTYGRIGVKV 200 + +L + S+ + R + Sbjct: 124 LIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGERDRI----FAHCYGLYDAHLKACN 179 Query: 201 WIYRGEVLPPAK 212 + +++ Sbjct: 180 VLDFDDLILLPT 191 >MTH864 [K] COG0640 Predicted transcriptional regulators Length = 258 Score = 72.4 bits (176), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 53/192 (27%), Positives = 95/192 (49%), Gaps = 9/192 (4%) Query: 26 KDFGTLLMEDVKIREYLKGKLKDSSVSRIEIERAASRVNVTIHTAKPGMVIGKGGAEVEV 85 KDF + +I EYL+ +L+ + ++++ V ++ +PGMVIG+GG V Sbjct: 4 KDFVVEGLRRTRIDEYLEKELERAGYGGMDVQVTPMGTMVVVYAERPGMVIGRGGKTVRA 63 Query: 86 LRSAVTTIAGGKKVHININEIKHPELDAILVAESIAQQLERRVSFRRALKQAIQRTMRSG 145 + + + + + E+ PEL+ ++A IA L+R + FRR ++R M +G Sbjct: 64 ITQKLKNKFDLENPQVEVKEVDVPELNPKIMAHKIAAMLQRGMHFRRVAYTTMRRIMAAG 123 Query: 146 AKGIKTQVGGRLGGAEIAR---SEGYSE--GTVPLHTLRADIDYGTAEAHTTYGRIGVKV 200 A+G++ + G++ GA A ++GY + G + +R G A G +GV V Sbjct: 124 AQGVEVTISGKIRGARSATAKFTDGYIKKCGEPSVKHVRE----GFATVQLKPGVLGVYV 179 Query: 201 WIYRGEVLPPAK 212 I +V+ P K Sbjct: 180 RIMPPDVVLPDK 191 >MTH855_1 [S] COG1900 Uncharacterized conserved protein Length = 258 Score = 72.4 bits (176), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 53/192 (27%), Positives = 95/192 (49%), Gaps = 9/192 (4%) Query: 26 KDFGTLLMEDVKIREYLKGKLKDSSVSRIEIERAASRVNVTIHTAKPGMVIGKGGAEVEV 85 KDF + +I EYL+ +L+ + ++++ V ++ +PGMVIG+GG V Sbjct: 4 KDFVVEGLRRTRIDEYLEKELERAGYGGMDVQVTPMGTMVVVYAERPGMVIGRGGKTVRA 63 Query: 86 LRSAVTTIAGGKKVHININEIKHPELDAILVAESIAQQLERRVSFRRALKQAIQRTMRSG 145 + + + + + E+ PEL+ ++A IA L+R + FRR ++R M +G Sbjct: 64 ITQKLKNKFDLENPQVEVKEVDVPELNPKIMAHKIAAMLQRGMHFRRVAYTTMRRIMAAG 123 Query: 146 AKGIKTQVGGRLGGAEIAR---SEGYSE--GTVPLHTLRADIDYGTAEAHTTYGRIGVKV 200 A+G++ + G++ GA A ++GY + G + +R G A G +GV V Sbjct: 124 AQGVEVTISGKIRGARSATAKFTDGYIKKCGEPSVKHVRE----GFATVQLKPGVLGVYV 179 Query: 201 WIYRGEVLPPAK 212 I +V+ P K Sbjct: 180 RIMPPDVVLPDK 191 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.316 0.134 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 16,621,807 Number of extensions: 660782 Number of successful extensions: 1335 Number of sequences better than 1.0e-05: 28 Number of HSP's gapped: 1333 Number of HSP's successfully gapped: 28 Length of query: 221 Length of database: 38,378,431 Length adjustment: 102 Effective length of query: 119 Effective length of database: 26,614,363 Effective search space: 3167109197 Effective search space used: 3167109197 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 114 (48.5 bits)