BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0188.0044.p (214 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_adk [F] COG0563 Adenylate kinase and related kinases 269 3e-72 BH0155 [F] COG0563 Adenylate kinase and related kinases 265 3e-71 lin2760 [F] COG0563 Adenylate kinase and related kinases 247 1e-65 CAC3112 [F] COG0563 Adenylate kinase and related kinases 230 9e-61 L140714 [F] COG0563 Adenylate kinase and related kinases 217 8e-57 >BS_adk [F] COG0563 Adenylate kinase and related kinases Length = 217 Score = 269 bits (687), Expect = 3e-72, Method: Compositional matrix adjust. Identities = 135/214 (63%), Positives = 170/214 (79%) Query: 1 VNILFMGPPGAGKGTQAAVVVKELGIPHISTGDAFRLAIKQGTPVGLKAKSYIDQGLLVP 60 +N++ MG PGAGKGTQ +V++ GIPHISTGD FR A+K+ TP+GL+AKSYID+G LVP Sbjct: 1 MNLVLMGLPGAGKGTQGERIVEDYGIPHISTGDMFRAAMKEETPLGLEAKSYIDKGELVP 60 Query: 61 DDVTIGIVEERLQQSDCEKGFLLDGFPRTLSQAEALEDILSRLNRSLDHVINLNVDRGLL 120 D+VTIGIV+ERL + DCE+GFLLDGFPRT++QAEALE+IL + +D+VIN+ VD+ +L Sbjct: 61 DEVTIGIVKERLGKDDCERGFLLDGFPRTVAQAEALEEILEEYGKPIDYVINIEVDKDVL 120 Query: 121 MARLTGRRICTVCGTSYHLIFNPPKQEGICDIDGGALYQRPDDNEESVGKRLDEYDNKTA 180 M RLTGRRIC+VCGT+YHL+FNPPK GICD DGG LYQR DDNEE+V KRL+ +T Sbjct: 121 MERLTGRRICSVCGTTYHLVFNPPKTPGICDKDGGELYQRADDNEETVSKRLEVNMKQTQ 180 Query: 181 PLLTFYDNKGLLRQVNGENEINVVTSEIVSLLRG 214 PLL FY KG L VNG+ +I V +++ LL G Sbjct: 181 PLLDFYSEKGYLANVNGQQDIQDVYADVKDLLGG 214 >BH0155 [F] COG0563 Adenylate kinase and related kinases Length = 217 Score = 265 bits (678), Expect = 3e-71, Method: Compositional matrix adjust. Identities = 126/214 (58%), Positives = 162/214 (75%) Query: 1 VNILFMGPPGAGKGTQAAVVVKELGIPHISTGDAFRLAIKQGTPVGLKAKSYIDQGLLVP 60 +N++ MG PGAGKGTQA ++++ GIPHISTGD FR A+K T +GLKAKSY+D G LVP Sbjct: 1 MNLILMGLPGAGKGTQAEKIIEKYGIPHISTGDMFRAAMKNETELGLKAKSYMDAGELVP 60 Query: 61 DDVTIGIVEERLQQSDCEKGFLLDGFPRTLSQAEALEDILSRLNRSLDHVINLNVDRGLL 120 D+VTIGIV +RL Q DC+ GFLLDGFPRT++QAEALEDIL+ L++ LD+VIN++V LL Sbjct: 61 DEVTIGIVRDRLSQDDCQNGFLLDGFPRTVAQAEALEDILASLDKKLDYVINIDVPEQLL 120 Query: 121 MARLTGRRICTVCGTSYHLIFNPPKQEGICDIDGGALYQRPDDNEESVGKRLDEYDNKTA 180 M RLTGRR+ G +YH+IFNPPK EGICD+DG L QR DD E+V KRL+ + Sbjct: 121 MDRLTGRRVSPTSGRTYHVIFNPPKVEGICDVDGSELIQRDDDKPETVKKRLEVNQKQAQ 180 Query: 181 PLLTFYDNKGLLRQVNGENEINVVTSEIVSLLRG 214 PL+ FY KG L+ +NG+ +I+ V +I LL+G Sbjct: 181 PLIDFYSEKGYLQNINGDQDISRVFEDINELLKG 214 >lin2760 [F] COG0563 Adenylate kinase and related kinases Length = 215 Score = 247 bits (630), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 121/212 (57%), Positives = 151/212 (71%) Query: 1 VNILFMGPPGAGKGTQAAVVVKELGIPHISTGDAFRLAIKQGTPVGLKAKSYIDQGLLVP 60 + ++ MG PGAGKGTQA +V++ IPHISTGD FR A+K T +G KAKS++D G LVP Sbjct: 1 MKLVLMGLPGAGKGTQAEQIVEKYNIPHISTGDMFRAAMKNNTELGKKAKSFMDNGDLVP 60 Query: 61 DDVTIGIVEERLQQSDCEKGFLLDGFPRTLSQAEALEDILSRLNRSLDHVINLNVDRGLL 120 D+VT GIV ERL + D + GFLLDGFPRT+ QAE LE+ILS L LD VIN+ VD+ +L Sbjct: 61 DEVTNGIVRERLAEDDAKNGFLLDGFPRTVEQAEELENILSDLGTELDAVINIEVDKDVL 120 Query: 121 MARLTGRRICTVCGTSYHLIFNPPKQEGICDIDGGALYQRPDDNEESVGKRLDEYDNKTA 180 M RLTGR IC CG +YH I+NPPK G CD+DGG LYQR DD +E+V RL+ +T Sbjct: 121 MKRLTGRWICRTCGKTYHEIYNPPKVPGKCDLDGGELYQREDDKKETVENRLNVNMKQTK 180 Query: 181 PLLTFYDNKGLLRQVNGENEINVVTSEIVSLL 212 PLL FY KG L +NGE +IN V ++ +L Sbjct: 181 PLLDFYSEKGKLHSINGEQDINDVFVDVEKIL 212 >CAC3112 [F] COG0563 Adenylate kinase and related kinases Length = 215 Score = 230 bits (587), Expect = 9e-61, Method: Compositional matrix adjust. Identities = 106/212 (50%), Positives = 153/212 (72%) Query: 1 VNILFMGPPGAGKGTQAAVVVKELGIPHISTGDAFRLAIKQGTPVGLKAKSYIDQGLLVP 60 + I+ +GPPGAGKGTQA ++ E IPHISTGD FR I T +G+KAK Y+D+GLLVP Sbjct: 1 MKIILLGPPGAGKGTQAKLISSEFSIPHISTGDIFRANISGKTELGMKAKGYMDKGLLVP 60 Query: 61 DDVTIGIVEERLQQSDCEKGFLLDGFPRTLSQAEALEDILSRLNRSLDHVINLNVDRGLL 120 D++TI IV++R+ + DC+ GFLLDGFPRT++QAEAL+ L +D + ++V R + Sbjct: 61 DELTIDIVKDRISKDDCKSGFLLDGFPRTVNQAEALDKFLVGRKEKIDCALLIDVPREKI 120 Query: 121 MARLTGRRICTVCGTSYHLIFNPPKQEGICDIDGGALYQRPDDNEESVGKRLDEYDNKTA 180 R+TGRR+C+ CG SYH+ +NP K EGICD+ G + QR DD+E++V +RLD YD +T Sbjct: 121 FNRMTGRRVCSKCGASYHIEYNPTKVEGICDLCGSPVVQRKDDSEDTVKERLDVYDRQTE 180 Query: 181 PLLTFYDNKGLLRQVNGENEINVVTSEIVSLL 212 PL+ +Y N+ +L+ V+G +I+ V +I ++L Sbjct: 181 PLVVYYRNEAVLKSVDGTQDIDKVFEDIRNVL 212 >L140714 [F] COG0563 Adenylate kinase and related kinases Length = 215 Score = 217 bits (553), Expect = 8e-57, Method: Compositional matrix adjust. Identities = 113/214 (52%), Positives = 148/214 (69%), Gaps = 2/214 (0%) Query: 1 VNILFMGPPGAGKGTQAAVVVKELGIPHISTGDAFRLAIKQGTPVGLKAKSYIDQGLLVP 60 +N+L MG PGAGKGTQA +VK G+ HISTGD FR A+K T +G AKS+ID+G LVP Sbjct: 1 MNLLIMGLPGAGKGTQAEFIVKNYGVNHISTGDMFRAAMKNETEMGKLAKSFIDKGELVP 60 Query: 61 DDVTIGIVEERLQQSDCE-KGFLLDGFPRTLSQAEALEDILSRLNRSLDHVINLNVDRGL 119 D+VT GIV+ERL Q D + GFLLDG+PRT+ QA AL+ +L L LD V+N+ V+ + Sbjct: 61 DEVTNGIVKERLAQDDIKASGFLLDGYPRTIDQAHALDTMLEELGIKLDAVVNIVVNPDI 120 Query: 120 LMARLTGRRICTVCGTSYHLIFNPPKQEGICDIDGGA-LYQRPDDNEESVGKRLDEYDNK 178 L+ RL+GR IC CG +YH IFNP K EG+CD+ G LYQR DD E+V RLD + Sbjct: 121 LVDRLSGRYICRNCGATYHKIFNPTKVEGVCDVCGSHDLYQRADDVPETVKNRLDVNIKE 180 Query: 179 TAPLLTFYDNKGLLRQVNGENEINVVTSEIVSLL 212 +AP++ Y GL++ + GE EI+ VT +I +L Sbjct: 181 SAPIIEHYTELGLVKNIEGEQEISQVTEDIKKVL 214 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.140 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 16,855,753 Number of extensions: 710887 Number of successful extensions: 4148 Number of sequences better than 1.0e-05: 24 Number of HSP's gapped: 4130 Number of HSP's successfully gapped: 24 Length of query: 214 Length of database: 38,378,431 Length adjustment: 102 Effective length of query: 112 Effective length of database: 26,614,363 Effective search space: 2980808656 Effective search space used: 2980808656 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 113 (48.1 bits)