BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0184.0008.p (341 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH1928 [K] COG1609 Transcriptional regulators 189 7e-48 TM1200 [K] COG1609 Transcriptional regulators 186 4e-47 VC1721 [K] COG1609 Transcriptional regulators 184 1e-46 HI1635 [K] COG1609 Transcriptional regulators 181 2e-45 RSc1014 [K] COG1609 Transcriptional regulators 177 2e-44 >BH1928 [K] COG1609 Transcriptional regulators Length = 335 Score = 189 bits (479), Expect = 7e-48, Method: Compositional matrix adjust. Identities = 110/334 (32%), Positives = 184/334 (55%), Gaps = 5/334 (1%) Query: 6 MVSIKDVAKHAGVSISAVSKTLNGYSDVSEATRRKILQAAQELNYSPNMLAKNLKHKVTK 65 M +I D+AK G SI+ VSK LN Y+DVS+ R+K++ A E+ Y P+ A+ L K + Sbjct: 1 MATIYDIAKKTGYSITTVSKVLNNYTDVSDKARKKVMDAVTEMGYFPSSSARMLTTKKSW 60 Query: 66 TIALIISNFEKANGKDGVVFQIISGVYAAATRYGYEVVIYTRSLSEQQDKSYWQFCNDHK 125 TI ++ + +I R+GY+++ + + + K+Y + Sbjct: 61 TIGVVFVESAGIGMEHPFFSSVIENFKKNVERFGYDLLFASNQIGNEA-KTYLEHFRYRG 119 Query: 126 IAGVVISGLRTTDPYFEELIDSDIPSVVIDAETIGPHAGSVITDNLEAARLAVQYLISKG 185 + G+V+ DP E+L+ +DIPSVVID ++ G A V +DN + LAV YL+S G Sbjct: 120 VDGIVVVCSLLNDPEVEKLMKADIPSVVIDLDSKGSSA--VYSDNEYGSELAVDYLVSLG 177 Query: 186 HQEIGMVNGHRYATVSIKREQGYREALEEAGLTFIPSRVVEADF-TEEGAYELTEGFISA 244 H+ I ++G + V ++R +G+++A+++ L+ +V+ F T EG E + Sbjct: 178 HRSIAHISGDQGLFVGVQRLKGFKDAIQKLNLSISDEYIVDGGFFTYEGGQRAMEALLRN 237 Query: 245 NPRLTAVFVASDLMAIGVMKRITELGLRVPEDISLMGFDDIVLCSYTTPKLSTIRQDFVG 304 R TAV+ A DLMA+G + I + GL VPED S++GFDDI + YT P L+TIRQ+ Sbjct: 238 RVRPTAVYAAGDLMALGAIDTIRKHGLSVPEDFSIVGFDDIQMIRYTAPALTTIRQNTDL 297 Query: 305 LGYAALEQVVKMLERNTPGYNKI-LPFSIVDRET 337 +G A ++ + N + +P ++++R++ Sbjct: 298 IGKTAANLLLDQINENEKQSLSVKIPVTLIERDS 331 >TM1200 [K] COG1609 Transcriptional regulators Length = 333 Score = 186 bits (473), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 101/314 (32%), Positives = 180/314 (57%), Gaps = 7/314 (2%) Query: 3 KPVMVSIKDVAKHAGVSISAVSKTLNGYSDVSEATRRKILQAAQELNYSPNMLAKNLKHK 62 K V+I+D+A+ AGVSI+ VS+ LN D+SE TRRKIL+ AQEL Y N A +L+ K Sbjct: 2 KKKYVTIRDIAEKAGVSINTVSRALNNKPDISEETRRKILKIAQELGYVKNATASSLRSK 61 Query: 63 VTKTIALIISNFEKANGKDGVVFQIISGVYAAATRYGYEVVIY-TRSLSEQQDKSYWQFC 121 T + +II A+ + +++ G+ AA+ +YGY++++ T + E ++K+ + Sbjct: 62 QTNIVGVII-----ADSANPFYAEVLKGIEAASRKYGYQIMLMNTERIYENEEKA-IEVL 115 Query: 122 NDHKIAGVVISGLRTTDPYFEELIDSDIPSVVIDAETIGPHAGSVITDNLEAARLAVQYL 181 ++ G++I+ ++ + LI+ +P V++ + +D ++ LA ++L Sbjct: 116 LQRRVDGLLITPVQDRSDDIKTLIERKVPFVIVGRHFEELEVDEIHSDEVKGGYLATRHL 175 Query: 182 ISKGHQEIGMVNGHRYATVSIKREQGYREALEEAGLTFIPSRVVEADFTEEGAYELTEGF 241 I +G + I M++G+ + + + R +GYR+AL+E G+ F ++E D E Y Sbjct: 176 IERGRKNIIMISGYLFKSAAYMRLEGYRKALKEYGIPFSEKMIIETDIDIESGYRAMREA 235 Query: 242 ISANPRLTAVFVASDLMAIGVMKRITELGLRVPEDISLMGFDDIVLCSYTTPKLSTIRQD 301 I AVF +DL+A GV+K + E G R+PED++++G+DDIV S+ P L+T+R Sbjct: 236 IEKGLEFEAVFCYNDLLAFGVIKALKECGYRIPEDVAVVGYDDIVYSSFICPSLTTVRIK 295 Query: 302 FVGLGYAALEQVVK 315 +G+ A +++ Sbjct: 296 KFEMGFEAFRMLLQ 309 >VC1721 [K] COG1609 Transcriptional regulators Length = 336 Score = 184 bits (468), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 105/337 (31%), Positives = 192/337 (56%), Gaps = 11/337 (3%) Query: 6 MVSIKDVAKHAGVSISAVSKTLNGYSDVSEATRRKILQAAQELNYSPNMLAKNLKHKVTK 65 M +IKDVA+ AGVS + VS +N V+E T+ K+++A ++LNY+P+ +A++LK T+ Sbjct: 1 MATIKDVARLAGVSTTTVSHVINKTRFVAETTQEKVMEAVKQLNYAPSAVARSLKCNTTR 60 Query: 66 TIALIISNFEKANGKDGVVFQIISGVYAAATRYGYEVVIYTRSLSEQQDKSYWQFCNDHK 125 TI ++++ + ++I GV + R GY +++ ++ + Y + + + Sbjct: 61 TIGMLVTQ-----STNLFFSEVIDGVESYCYRQGYTLILCNTGGIYEKQRDYIRMLAEKR 115 Query: 126 IAGVVISGLRTTDPYFEELIDS--DIPSVVIDAETIGPHAGSVITDNLEAARLAVQYLIS 183 + G+++ T ++++D+ DIP VV+D HA +I ++ E LA +YL Sbjct: 116 VDGILVMCSDLTQE-LQDMLDAHKDIPKVVMDWGPETSHADKIIDNSEEGGYLATKYLTD 174 Query: 184 KGHQEIGMVNGHRYATVSIKREQGYREALEEAGLTFIPSRVVEADFTEEGAYELTEGFIS 243 +GH EI ++GH +R QG+R A+ EA LT ++E +F + A + I+ Sbjct: 175 RGHTEIACLSGHFVKAACQERIQGFRRAMAEAKLTVNEDWILEGNFECDTAVLAADKIIA 234 Query: 244 ANPRLTAVFVASDLMAIGVMKRITELGLRVPEDISLMGFDDIVLCSYTTPKLSTIRQDFV 303 + R TAVF +D MA+G+M R+ + G+R+PED+S++G+D+I L Y +P L+T+ Q Sbjct: 235 MDKRPTAVFCFNDTMALGLMSRLQQKGIRIPEDMSVIGYDNIELAEYFSPPLTTVHQPKR 294 Query: 304 GLGYAALEQVVKMLERNTPGYNKILPF--SIVDRETI 338 +G A E +++ + ++ +I IV+R+T+ Sbjct: 295 RVGKNAFEILLERI-KDKEHERRIFEMHPEIVERDTV 330 >HI1635 [K] COG1609 Transcriptional regulators Length = 336 Score = 181 bits (459), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 113/332 (34%), Positives = 181/332 (54%), Gaps = 14/332 (4%) Query: 6 MVSIKDVAKHAGVSISAVSKTLNGYSDVSEATRRKILQAAQELNYSPNMLAKNLKHKVTK 65 M +IKDVAK AGVS + VS +N V++ T +L A ++LNYSP+ +A++LK TK Sbjct: 1 MATIKDVAKMAGVSTTTVSHVINKTRFVAKDTEEAVLSAIKQLNYSPSAVARSLKVNTTK 60 Query: 66 TIALIISNFEKANGKDGVVFQIISGVYAAATRYGYEVVIYTRSLSEQQDKSYWQFCNDHK 125 +I +I++ E +II V R GY + T + ++ K++ + + Sbjct: 61 SIGMIVTTSEAP-----YFAEIIHSVEEHCYRQGYSLFCVTHKMDPEKVKNHLEMLAKKR 115 Query: 126 IAGVVISGLRTTDPYFEELID-SDIPSVVIDAETIGPHAGSVITDN--LEAARLAVQYLI 182 + G+++ T + L S IP VV+D GP+A + + D+ + LA ++LI Sbjct: 116 VDGLLVMCSEYTQDSLDLLSSFSTIPMVVMDW---GPNANTDVIDDHSFDGGYLATKHLI 172 Query: 183 SKGHQEIGMVNGHRYATVSIKREQGYREALEEAGLTFIPSRVVEADFTEEGAYELTEGFI 242 GH++IG++ G T + R +G+ +A+EEA LT PS V+E F E YE + Sbjct: 173 ECGHKKIGIICGELNKTTARTRYEGFEKAMEEAKLTINPSWVLEGAFEPEDGYECMNRLL 232 Query: 243 SANPRLTAVFVASDLMAIGVMKRITELGLRVPEDISLMGFDDIVLCSYTTPKLSTIRQDF 302 + TA+F +D+MA+G + +TE GLRVPED+S++G+DDI + P L+TI Q Sbjct: 233 TQEKLPTALFCCNDVMALGAISALTEKGLRVPEDMSIIGYDDIHASRFYAPPLTTIHQSK 292 Query: 303 VGLGYAALEQVVKMLERNTPGYNKILPFSIVD 334 + LG A+ +LER T + +S +D Sbjct: 293 LRLGRQAINI---LLERITHKDEGVQQYSRID 321 >RSc1014 [K] COG1609 Transcriptional regulators Length = 347 Score = 177 bits (449), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 103/324 (31%), Positives = 174/324 (53%), Gaps = 5/324 (1%) Query: 6 MVSIKDVAKHAGVSISAVSKTLNGYSDVSEATRRKILQAAQELNYSPNMLAKNLKHKVTK 65 M +IKDVA AGVS + VS +N V+ TR+++ +A + Y P+ +A++LKH+ T+ Sbjct: 1 MATIKDVAALAGVSFTTVSHVINNTRPVNSETRKRVEEAIRATRYVPSAVARSLKHRTTR 60 Query: 66 TIALIISNFEKANGKDGVVFQIISGVYAAATRYGYEVVIYTRSLSEQQDKSYWQFCNDHK 125 TI +++ N + + I V AAA GY V++ ++ + Y + + + Sbjct: 61 TIGVLVPT--ATNPYFAELARGIEDVCAAA---GYSVILCNSDDDPRKQRDYLRVLMEKR 115 Query: 126 IAGVVISGLRTTDPYFEELIDSDIPSVVIDAETIGPHAGSVITDNLEAARLAVQYLISKG 185 + G+++S + + L +S +P V++D T G A V D+ E A LA ++L+ G Sbjct: 116 VDGLIVSSAGPDNALLDALGESALPVVMVDRPTEGILADQVQIDHEEGAYLATRHLLELG 175 Query: 186 HQEIGMVNGHRYATVSIKREQGYREALEEAGLTFIPSRVVEADFTEEGAYELTEGFISAN 245 H+ I ++G +V+ R G+ AL EAG+ +RV E DFT G Y ++ Sbjct: 176 HRRIACISGPSTLSVTAGRLAGFHRALREAGVPEHAARVAEGDFTSPGGYRAARELLTTG 235 Query: 246 PRLTAVFVASDLMAIGVMKRITELGLRVPEDISLMGFDDIVLCSYTTPKLSTIRQDFVGL 305 TA+F ++DLM IG ++ ELG+ VP+++S++GFDDI L Y P LST+ Q L Sbjct: 236 ETPTAIFASNDLMGIGALRAAAELGIAVPKELSIIGFDDIELSRYVYPALSTVGQSIRQL 295 Query: 306 GYAALEQVVKMLERNTPGYNKILP 329 G +++ L + ++ +P Sbjct: 296 GETTASTLLEHLTDHAARHHHEIP 319 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.134 0.374 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 23,831,263 Number of extensions: 925295 Number of successful extensions: 4765 Number of sequences better than 1.0e-05: 181 Number of HSP's gapped: 4490 Number of HSP's successfully gapped: 183 Length of query: 341 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 234 Effective length of database: 26,037,693 Effective search space: 6092820162 Effective search space used: 6092820162 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 116 (49.3 bits)