BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0183.0008.p (615 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SP0662 [T] COG2972 Predicted signal transduction protein with a ... 164 3e-40 BH2727 [T] COG2972 Predicted signal transduction protein with a ... 155 2e-37 BH1909 [T] COG2972 Predicted signal transduction protein with a ... 143 1e-33 BH0792 [T] COG2972 Predicted signal transduction protein with a ... 142 1e-33 BS_yesM [T] COG2972 Predicted signal transduction protein with a... 137 4e-32 >SP0662 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 563 Score = 164 bits (416), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 139/573 (24%), Positives = 269/573 (46%), Gaps = 25/573 (4%) Query: 38 LIVLLALMIFVLSIHRIVFNQTLGRTSASSQQEVKLVSQSMKTVFQSVQNFSKFALINQD 97 L+V + + IF++ + + T S+SS E + S T+ Q+ + + Sbjct: 6 LLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGNSQTTISQTSHFIQSYIKKLET 65 Query: 98 TQNVLSRDT-----GADGDVSPLKSIHNTLAAMLETEPNIDSVIIESIGGDLYYTSNLTG 152 T L++ T + ++ I + +L+++ ++ +V++ + G + T + Sbjct: 66 TSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSDKDLKTVVLVTKSGQVISTDDSVQ 125 Query: 153 VTPQSLAIYPKDKIDAAKGGAVWVDTLKPSFLSGMTAKNMISVCRVIMSMEKGTPIGYIY 212 + S + A GA+ V L P+ S ++ +ISV + ++ KG +G + Sbjct: 126 MKTSSDMMAEDWYQKAIHQGAMPV--LTPARKSD--SQWVISVTQELVDA-KGANLGVLR 180 Query: 213 VNIDERTL-ARLYHNEQDNQNPTLVVNQEGVVISAYEAALVSRTVEDHSLARWVKSASGG 271 ++I TL A L + Q ++N+ + + + S + + ++ ++ + G Sbjct: 181 LDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQHTVYSSSSKMEAMKPYIDTGQGY 240 Query: 272 SRTERVGDKPYLVSLQRLDPYGWKVIHLVPTSELTNGYWKIALSIAVFGLISMLSAMVLS 331 + G K Y VS +++ W V+ + +L ++ ++ + S+L + L Sbjct: 241 TP----GHKSY-VSQEKIAGTDWTVLGVSSLEKLDQVRSQLLWTLLGASVTSLLVCLCLV 295 Query: 332 FVFARRLTRPLSELSEVIVEVGAGNFERRASAGSQDEVGRLGATFNEMVEHIQDLMLTIX 391 + +R PL +L E ++E+ +G RA E+ + FN M++ I LM+ I Sbjct: 296 WFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELREVTRQFNAMLDQIDQLMVAIR 355 Query: 392 XXXXXXXXXXXXXXYSQIKPHFLYNTLDTIRAMAVMTNAKEISSILKALGEFYRISLSNG 451 SQI PHFLYNTLDTI MA +++ + + K+L ++R++L+ G Sbjct: 356 SQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFHDSQRVVQVTKSLATYFRLALNQG 415 Query: 452 QELIAAAQEKRHLESYLYIQQIRF-KKLNYRISFEPGIESCQVPTMLLQPLVENAIHHGI 510 ++LI + E H+ YL+IQ+ R+ KL Y I+ ++ +P ++LQPLVENA++HGI Sbjct: 416 KDLICLSDEINHVRQYLFIQKQRYGDKLEYEINENVAFDNLVLPKLVLQPLVENALYHGI 475 Query: 511 RGMPDGGLCEITGSMERSGEERILCFIVRDNGKGMSEEEQRQIWLSSSEEGEYSFGLKNI 570 + G +++ + SG L + D+G G + S S+ GL+N+ Sbjct: 476 KEKEGQGHIKLSVQKQDSG----LVIRIEDDGVGFQDAGDS----SQSQLKRGGVGLQNV 527 Query: 571 QDRIQLRFGEAYGIVLSSEPGHGVEVKVRLPLI 603 R++L FG Y + + S P G +V++ + I Sbjct: 528 DQRLKLHFGANYHMKIDSRPQKGTKVEIYINRI 560 >BH2727 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 597 Score = 155 bits (391), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 117/422 (27%), Positives = 206/422 (48%), Gaps = 23/422 (5%) Query: 192 MISVCRVIMSMEKGTPIGYIYVNIDERTLARLYHNEQDNQNPTLVVNQEGVVISAYEAAL 251 MI +V++ G +Y++I ER L Y N L+VN EG +IS+ + + Sbjct: 178 MIVAAKVLLERSTENRYGIVYISIRERQLREFYEGYTTEGNKILIVNDEGQIISSNDQTM 237 Query: 252 VSRTVEDHSLARWVKSAS--GGSRTE-RVGDKPYLVSLQRLDPYGWKVIHLVPTSELTNG 308 + V D +L + S G T+ V DK Y++ + L + +I+LV ++ Sbjct: 238 IG--VTDQALLHASREMSELGLEYTDVHVFDKDYMILSEYLPTFNMYLINLVDKRMISEN 295 Query: 309 YWKIALSIAVFGLISMLSAMVLSFVFARRLTRPLSELSEVIVEVGAGNFERRASAGSQDE 368 + I +LS ++ F+ RR+T+ L+ + E I + +F+R A E Sbjct: 296 LLSKKEIYFIIIGIIVLSVFII-FILLRRMTKSLTNVVEQISNMAKYHFKRPLVASGGYE 354 Query: 369 VGRLGATFNEMVEHIQDLMLTIXXXXXXXXXXXXXXXYSQIKPHFLYNTLDTIRAMAVMT 428 ++ FN+M+ +Q+ + + QI PHFLYNTL +++ M Sbjct: 355 TEQIANAFNDMLRELQEYVDLVVETEQKQRKAELKALQHQINPHFLYNTLTSVKFMVQQG 414 Query: 429 NAKEISSILKALGEFYRISLSNGQELIAAAQEKRHLESYLYIQQIRFK---KLNYRISFE 485 + ++ + + AL + +L + E I QE ++ Y+ I Q R+ K++Y +S Sbjct: 415 DKEKAAETILALITLLQNALGHINETITVEQELTIIKKYVLINQARYGERIKVHYFVS-- 472 Query: 486 PGIESCQVPTMLLQPLVENAIHHGIRGMPDGGLCEITGSMERSGEERILCFIVRDNGKGM 545 P Q+P ++LQP +ENA H + G ++ +++ +E++L IV DNG GM Sbjct: 473 PECLPYQMPKLVLQPFIENAFFHAFNKKKE-GFIQVMAAVK---DEKLLFEIV-DNGDGM 527 Query: 546 SEEEQRQIWLSSSEEGE----YSFGLKNIQDRIQLRFGEAYGIVLSSEPGHGVEVKVRLP 601 E ++ LSS G+ + G++N+ +RIQL +G+ YG+ ++S G+G V V LP Sbjct: 528 DLE---KVSLSSRYHGKRQLFHGIGVRNVHERIQLLYGKDYGVEMTSNIGNGTVVHVILP 584 Query: 602 LI 603 L+ Sbjct: 585 LL 586 >BH1909 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 597 Score = 143 bits (360), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 120/447 (26%), Positives = 216/447 (48%), Gaps = 33/447 (7%) Query: 183 FLSGMTAKNM--ISVCRVIMSMEKGTPIGYIYVNIDERTLARLYHNEQDNQNPTLVVNQE 240 +L T KN +S+ + + +E G+ G + + +D R L R+ E T++V++ Sbjct: 162 YLEDETKKNQAYLSMVKRLNFLEYGSA-GVLVITVDPRKLDRILQQES---FTTMIVDER 217 Query: 241 GVVISAYEAALVSRTVED----HSLAR----WVKSASGGSRTERVGDKPYLVSLQRLDPY 292 + + + + + + + H + + + G ++ + D YL +LQ + Sbjct: 218 NRIAATNQREYIGKDLHEVIDFHEMIQEGPAIYEGKMNGEPSQIIVD--YL-TLQ-MSQS 273 Query: 293 GWKVIHLVPTSELTNGYWKIALSIAVFGLISMLSAMVLSFVFARRLTRPLSELSEVIVEV 352 K+I +V + ++++ A + M A++L F+ +++ LS LSE I +V Sbjct: 274 ELKIISIVTKEHIMKDAKRLSIMGATVTMGGMAVAVLLIVHFSWLISKRLSHLSERINQV 333 Query: 353 GAGNFERRASAGSQDEVGRLGATFNEMVEHIQDLMLTIXXX-------XXXXXXXXXXXX 405 +G+ + + +DE+G+L FN+MV +++ L+ + Sbjct: 334 ASGDLKTKIVVDGKDEIGQLSVQFNQMVANLRSLIHQVHETNRQKRLLEKSQNEIKLKML 393 Query: 406 YSQIKPHFLYNTLDTIRAMAVMTNAKEISSILKALGEFYRISLSNGQELIAAAQEKRHLE 465 SQI PHFL+NTL++IR + M EI+ ++K LG+ R SL I E + Sbjct: 394 ASQINPHFLFNTLESIRMKSHMKGETEIAKVVKQLGKLMRKSLEVTGHHIPLRNELDMVR 453 Query: 466 SYLYIQQIRF-KKLNYRISFEPGIESCQVPTMLLQPLVENAIHHGIRGMPDGGLCEITGS 524 YL IQ R+ +L+Y + +P E ++ +++QPLVENA+ HG+ DGG I+ Sbjct: 454 CYLEIQTFRYGDRLHYELYIDPQSEMVEILPLIIQPLVENAVIHGLERTEDGGTVTISTI 513 Query: 525 MERSGEERILCFIVRDNGKGMSEE--EQRQIWLSSSEEGE-YSFGLKNIQDRIQLRFGEA 581 + +G + L IV D+G GM EE E Q L +E + GL N+ R+QL +G+ Sbjct: 514 V--NGND--LTVIVNDDGCGMDEEKLEAIQNMLHHPQEVDGNKIGLLNVHKRLQLTYGKT 569 Query: 582 YGIVLSSEPGHGVEVKVRLPLIMQADE 608 G+++ S G G V+ + I D+ Sbjct: 570 SGLIIESAKGKGTCVRFTISQIRGDDD 596 >BH0792 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 587 Score = 142 bits (359), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 97/337 (28%), Positives = 172/337 (51%), Gaps = 14/337 (4%) Query: 274 TERVGDKPYLVSLQRLDPYGWKVIHLVPTSELTNGYWKIALSIAVFGLISMLS--AMVLS 331 T+++ + YL+ G+ V +VP SEL+ + I +F LI +L+ ++ L Sbjct: 247 TQQLVNNRYLIQSSIEPSTGFMVASIVPRSELSQLF---HYKITMFLLILLLTVVSIALP 303 Query: 332 FVFARRLTRPLSELSEVIVEVGAGNFERRASAGS-QDEVGRLGATFNEMVEHIQDLMLTI 390 +V R +++L + + EV +G R G+ D++ + TFNE ++ ++D + + Sbjct: 304 YVSLRGYLTRVNDLVQTMKEVQSGQLSVRIETGNVDDDLAMISNTFNETLDELEDYIEKV 363 Query: 391 XXXXXXXXXXXXXXXYSQIKPHFLYNTLDTIRAMAVMTNAKEISSILKALGEFYRISLSN 450 SQI PHFLYNTL+ IR ++ + + ++ L +R SL + Sbjct: 364 YFSKLKQTEAELANLQSQINPHFLYNTLEAIRMKSLSEGGRTTAKMIVQLSYLFRYSLKS 423 Query: 451 GQELIAAAQEKRHLESYLYIQQIRF-KKLNYRISFEPGIESCQVPTMLLQPLVENAIHHG 509 +L+ E +H+E Y+ + IRF +L ++++ E + VP +LQPL+EN + HG Sbjct: 424 A-DLVTIGDELQHVEQYVELFNIRFPNQLTFQVAVEEKHKHYVVPPFILQPLIENFLIHG 482 Query: 510 IRGMPDGGLCEITGSMERSGEERILCFIVRDNGKGMSEEEQRQI--WLSSSEEGEYSFGL 567 + D I +E+ L + DNGKG+ ++ +I LS +E +S GL Sbjct: 483 FKRERDDNQINIIIQ----EKEQTLQIQIMDNGKGIPRKKVEEINERLSMTENSSHSIGL 538 Query: 568 KNIQDRIQLRFGEAYGIVLSSEPGHGVEVKVRLPLIM 604 N+ R++LR+GE +G+ + SEP V +R P+I+ Sbjct: 539 FNVNQRLRLRYGERFGVSVQSEPDVCTIVTIRTPMII 575 >BS_yesM [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 577 Score = 137 bits (346), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 144/592 (24%), Positives = 276/592 (46%), Gaps = 50/592 (8%) Query: 30 RKILISNILIVLLALM-----IFVLSIHRIVFNQTLGRTSASSQQEVKLVSQSMKTVFQS 84 R++ I + L V L+L+ +FV S + F+ + S + +++ S+ ++ + Sbjct: 10 RRMKIKDKLFVFLSLIMAVSFLFVYSGVQYAFHVYDEQIYRKSSEVLRMSSERIEDELKK 69 Query: 85 VQNFSKFALINQDTQNVLSRDTGADG-DVSPLKS-IHNTLAAMLETEPNIDSV-IIESIG 141 +++ S + ++ Q +LS D D +K + + LA E IDS+ +I++ G Sbjct: 70 IEDVSYEIITDEQIQRILSMQNRDDTYDQYQMKQELWDQLAGYASDEKYIDSIHVIDARG 129 Query: 142 GDLYYTSNLTGVTPQSLA-IYPKDKIDAAKGGAVWVDTLKPSFLSGMTAKNMISVCRVIM 200 + S+ + + Q ++ + K A G +W+ TL S ++A+ + S ++ + Sbjct: 130 SEYSAGSSSSDLLQQEQEEVFKRAK--AKSGRNLWM-TLGGSDPVLISARQIRSYHQLSL 186 Query: 201 SMEKGTPIGYIYVNIDERTLAR-LYHNEQDNQNPTLVVNQEG-VVISAYEAALVSRTVED 258 + +G + + ++ + + R + + D+ ++ +Q G +V +A+ +A V Sbjct: 187 N-----GLGMVLIQVNVKQMIRDVPKDWGDSVGDIMIADQGGNLVYTAHASAHVPEA--- 238 Query: 259 HSLARWVKSASGGSRTERVGDKPYLVSLQRLDPYGWKVIHLVPTSELTNGYWKIALSIAV 318 A+ G ++ G K Y +S + W +++P ++ + KI+ V Sbjct: 239 ---AKETLKHPGYDLIKKNG-KRYFISYLQSSYQNWSYYNVIPFDQM---FAKISFMKTV 291 Query: 319 FGLISMLSAMVLSFVFARRL----TRPLSELSEVIVEVGAGNFERRASAG----SQDEVG 370 G +L V+ +F R++ T P+ +L + V E S +QDE G Sbjct: 292 IGTCFLLFFCVV-LLFGRKIANSITEPIEQLVTAMKSVQHSGIEAGVSLSLPEHTQDEAG 350 Query: 371 RLGATFNEMVEHIQDLMLTIXXXXXXXXXXXXXXXYSQIKPHFLYNTLDTIRAMAVMTNA 430 L F M++ I +LM +QI PHFLYNTL++I +A Sbjct: 351 MLNRHFTVMMKRINELMEENVEKQLIIKETELKALQAQINPHFLYNTLESINWLAKANQQ 410 Query: 431 KEISSILKALGEFYRISLSNGQELIAAAQEKRHLESYLYIQQIRF-KKLNYRISFEPGIE 489 K+IS ++++LG R S+ ++++ +E + Y+ IQ+ RF ++L + + + ++ Sbjct: 411 KQISKMVESLGFLLRNSIHMKKDIVTIQEEADIVRHYMTIQRFRFEERLKFTLDIDDEVK 470 Query: 490 SCQVPTMLLQPLVENAIHHGIRGMPDGGLCEITGSMERSGEERILCFIVRDNGKGMSEEE 549 C +P + LQPL ENAI + + P C I +++ + +C V DNG GM Sbjct: 471 HCLIPKLTLQPLAENAIQYALE--PFTRPCAIRIQAKKA--KGCVCITVEDNGPGMDG-- 524 Query: 550 QRQIWLSSSEEGEYSFGLKNIQDRIQLRFGEAYGIVLSSEPGHGVEVKVRLP 601 +I S+ G GL NI++RI L FGE YG+ + SE G + + +P Sbjct: 525 --RILESTGGRG---IGLWNIRERISLTFGEPYGLRIHSEHEKGTRIVITIP 571 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.134 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 40,366,933 Number of extensions: 1585799 Number of successful extensions: 14565 Number of sequences better than 1.0e-05: 30 Number of HSP's gapped: 14513 Number of HSP's successfully gapped: 30 Length of query: 615 Length of database: 38,378,431 Length adjustment: 112 Effective length of query: 503 Effective length of database: 25,461,023 Effective search space: 12806894569 Effective search space used: 12806894569 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 119 (50.4 bits)