BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0181.0003.p (588 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_yesM [T] COG2972 Predicted signal transduction protein with a... 160 8e-39 BH2110 [T] COG2972 Predicted signal transduction protein with a ... 137 6e-32 SP0662 [T] COG2972 Predicted signal transduction protein with a ... 136 9e-32 BH1122 [T] COG2972 Predicted signal transduction protein with a ... 123 1e-27 BH0792 [T] COG2972 Predicted signal transduction protein with a ... 122 1e-27 >BS_yesM [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 577 Score = 160 bits (404), Expect = 8e-39, Method: Compositional matrix adjust. Identities = 103/368 (27%), Positives = 176/368 (47%), Gaps = 23/368 (6%) Query: 215 ADQKLTADLIRYLDKHSPDSSTQHVISLGH-------KNYLVSSVKSSYLEWYLVDVVPL 267 ADQ + H P+++ + + G+ K Y +S ++SSY W +V+P Sbjct: 219 ADQGGNLVYTAHASAHVPEAAKETLKHPGYDLIKKNGKRYFISYLQSSYQNWSYYNVIPF 278 Query: 268 DRILGPISVSRNLFYVSMLLLFVVGISASILLYQNVQRPIKKLIKGLRRVQ----RGDYS 323 D++ IS + + LL F V + + ++ PI++L+ ++ VQ S Sbjct: 279 DQMFAKISFMKTVIGTCFLLFFCVVLLFGRKIANSITEPIEQLVTAMKSVQHSGIEAGVS 338 Query: 324 VRLHSEDHNEFSFLFYRFNDMSHQIQDLIENVFNEKIRAREATLKQLQAQINPHFLYNCL 383 + L +E L F M +I +L+E +++ +E LK LQAQINPHFLYN L Sbjct: 339 LSLPEHTQDEAGMLNRHFTVMMKRINELMEENVEKQLIIKETELKALQAQINPHFLYNTL 398 Query: 384 GFIINMAQMKDEEAVVSMAYNLSAYYRYTTRMERDTATLDDEVRLLVNYLDIQKLR-NGR 442 I +A+ ++ + M +L R + M++D T+ +E ++ +Y+ IQ+ R R Sbjct: 399 ESINWLAKANQQKQISKMVESLGFLLRNSIHMKKDIVTIQEEADIVRHYMTIQRFRFEER 458 Query: 443 IEYHIDIPQEMLSYSIPRLLLQPIVENSVIHGVGKSYSSGEIRISGECSGGCCRVYIDDD 502 +++ +DI E+ IP+L LQP+ EN++ + + IRI + + GC + ++D+ Sbjct: 459 LKFTLDIDDEVKHCLIPKLTLQPLAENAIQYALEPFTRPCAIRIQAKKAKGCVCITVEDN 518 Query: 503 GPGLSPEQQEALNRKMREPLQEEMGCGLWNTNQRLIHQFGNHSALHFTESPLGGFRTEIV 562 GPG+ E+ + G GLWN +R+ FG L G T IV Sbjct: 519 GPGMDGRILESTGGR---------GIGLWNIRERISLTFGEPYGLRIHSEHEKG--TRIV 567 Query: 563 WEIPAQEE 570 IP + E Sbjct: 568 ITIPCRNE 575 >BH2110 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 585 Score = 137 bits (344), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 97/328 (29%), Positives = 166/328 (50%), Gaps = 19/328 (5%) Query: 255 SYLE-WYLVDVVPLDRILGPISVSRNLFYV--SMLLLFVVGISASILLYQNVQRPIKKLI 311 +YLE W + + + IL + SR + S+ LLF + +L+ +++ + +++ Sbjct: 259 NYLEGWRVAGTISENEILEELYKSREFIVILASINLLFPTLLI--VLISKSIHSRLLRVL 316 Query: 312 KGLRRVQRGDYSVRLHSEDHNEFSFLFYRFNDMSHQIQDLIENVFNEKI-------RARE 364 K ++R+++ + + D +E L FN MS I LI V+ I R ++ Sbjct: 317 KHMKRMKKQKFDIINFPGDKDEIGELTNEFNKMSQTINRLINEVYASNIEKKDLQLREKQ 376 Query: 365 ATLKQLQAQINPHFLYNCLGFIINMAQMKDEEAVVSMAYNLSAYYRYTTRMERDTATLDD 424 A L LQ+QINPHFL+N L I + +K E+ + N++ +R + +D T+ D Sbjct: 377 AQLSALQSQINPHFLFNALETIRMRSMIKGEKETAKIIQNMAKIFRNSLTWGKDWVTVRD 436 Query: 425 EVRLLVNYLDIQKLRNG-RIEYHIDIPQEMLSYSIPRLLLQPIVENSVIHGVGKSYSSGE 483 E+ L++ +L+IQK R G ++EY +DI +E Y IP ++ P VEN+ IHG+ G Sbjct: 437 ELCLIICFLEIQKYRFGDKMEYELDIDEEAYDYIIPNMVFLPFVENASIHGIESVKEKGI 496 Query: 484 IRISGECSGGCCRVYIDDDGPGLSPEQQEALNRKMREPLQEEMG--CGLWNTNQRLIHQF 541 I+I E + G I D+G G+ E+ +L ++ +E MG G+ N RL + Sbjct: 497 IQIRVEKNDGEIVYEISDNGAGMDEEKLASLIETLKN--EENMGENVGIKNVYYRLKLHY 554 Query: 542 GNHSALHFTESPLGGFRTEIVWEIPAQE 569 NH P G +I ++PA++ Sbjct: 555 KNHFDFSINSRPGQGTTVQI--KLPAEK 580 >SP0662 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 563 Score = 136 bits (343), Expect = 9e-32, Method: Compositional matrix adjust. Identities = 113/402 (28%), Positives = 192/402 (47%), Gaps = 30/402 (7%) Query: 171 GSDL-VVEASFSSENIQNMLDTYKTGGQGDPFLYHKGETPILNRTADQKLTADLIRYLDK 229 G++L V+ S E ++ L+ + G QG F+ ++ + + Q ++ Sbjct: 173 GANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYH---PQHTVYSSSSKMEA 229 Query: 230 HSPDSSTQHVISLGHKNYLVSSVKSSYLEWYLVDVVPLDRILGPISVSRNLFYVSMLLLF 289 P T + GHK+Y VS K + +W ++ V L++ L + S LL Sbjct: 230 MKPYIDTGQGYTPGHKSY-VSQEKIAGTDWTVLGVSSLEK-LDQVR--------SQLLWT 279 Query: 290 VVGISASILL------YQNVQR---PIKKLIKGLRRVQRGDYSVRLHSEDHNEFSFLFYR 340 ++G S + LL + +++R P+K L + + + G ++R E + + Sbjct: 280 LLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELREVTRQ 339 Query: 341 FNDMSHQIQDLIENVFNEKIRAREATLKQLQAQINPHFLYNCLGFIINMAQMKDEEAVVS 400 FN M QI L+ + +++ R+ L+ L +QINPHFLYN L II MA+ D + VV Sbjct: 340 FNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFHDSQRVVQ 399 Query: 401 MAYNLSAYYRYTTRMERDTATLDDEVRLLVNYLDIQKLRNG-RIEYHIDIPQEMLSYSIP 459 + +L+ Y+R +D L DE+ + YL IQK R G ++EY I+ + +P Sbjct: 400 VTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINENVAFDNLVLP 459 Query: 460 RLLLQPIVENSVIHGVGKSYSSGEIRISGECSGGCCRVYIDDDGPGLSPEQQEALNRKMR 519 +L+LQP+VEN++ HG+ + G I++S + + I+DDG G + ++ R Sbjct: 460 KLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQDAGDSSQSQLKR 519 Query: 520 EPLQEEMGCGLWNTNQRLIHQFGNHSALHFTESPLGGFRTEI 561 G GL N +QRL FG + + P G + EI Sbjct: 520 G------GVGLQNVDQRLKLHFGANYHMKIDSRPQKGTKVEI 555 >BH1122 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 586 Score = 123 bits (308), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 94/306 (30%), Positives = 136/306 (44%), Gaps = 9/306 (2%) Query: 258 EWYLVDVVPLDRILGPISVSRNLFYVSMLLLFVVGISASILLYQNVQRPIKKLIKGLRRV 317 EW L V P + + + ++ VV + + L + PI +L L + Sbjct: 269 EWTLKQVTPYSELTEGSRRMAAILVIIGAIMIVVALLVTYSLTKKFTTPIYELKNVLSKY 328 Query: 318 QRGDYSVRLHSEDHNEFSFLFYRFNDMSHQIQDLIENVFNEKIRAREATLKQLQAQINPH 377 D S L S+ NEF LF + + + +L ++ + R REA +K LQA INPH Sbjct: 329 PDQDLSGELPSDYRNEFGELFEGYKGLIRRNNELYRSLHRQYKRQREAEIKALQANINPH 388 Query: 378 FLYNCLGFIINMAQMKDEEAVVSMAYNLSAYYRYTTRMERDTATLDDEVRLLVNYLDIQK 437 FLYN L + MA K + + M NL R L+ EV L YL IQK Sbjct: 389 FLYNTLDQLNWMAIEKGDRTMSHMLENLGQMLRIGLSNGESILPLEKEVEYLKYYLKIQK 448 Query: 438 LRNG-RIEYHIDIPQEMLSYSIPRLLLQPIVENSVIHGVGKSYSSGEIRISGECSGGCCR 496 L+ G R+ Y +D+P + Y IP+L LQP VEN IHG + GE+ I Sbjct: 449 LKMGERLTYTVDVPVMLYRYLIPKLTLQPFVENCFIHGF-QDGRDGEVVIRAMEDQNHIV 507 Query: 497 VYIDDDGPGLSPEQQEALNRKMREPLQEEMGCGLWNTNQRLIHQFGNHSALHFTESPLGG 556 + I D+G G P + M G G+ N +RL F ++++H T GG Sbjct: 508 MTIQDNGIGFQPVTTKRSKLDMG-------GYGIRNVMERLDVYFDRYASVHVTGDEQGG 560 Query: 557 FRTEIV 562 +I+ Sbjct: 561 TLVKII 566 >BH0792 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 587 Score = 122 bits (307), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 81/314 (25%), Positives = 154/314 (49%), Gaps = 4/314 (1%) Query: 242 LGHKNYLVSSVKSSYLEWYLVDVVPLDRILGPISVSRNLFYVSMLLLFVVGISASILLYQ 301 L + YL+ S + + +VP + +F + +LLL VV I+ + + Sbjct: 250 LVNNRYLIQSSIEPSTGFMVASIVPRSELSQLFHYKITMFLL-ILLLTVVSIALPYVSLR 308 Query: 302 NVQRPIKKLIKGLRRVQRGDYSVRLHSED-HNEFSFLFYRFNDMSHQIQDLIENVFNEKI 360 + L++ ++ VQ G SVR+ + + ++ + + FN+ +++D IE V+ K+ Sbjct: 309 GYLTRVNDLVQTMKEVQSGQLSVRIETGNVDDDLAMISNTFNETLDELEDYIEKVYFSKL 368 Query: 361 RAREATLKQLQAQINPHFLYNCLGFIINMAQMKDEEAVVSMAYNLSAYYRYTTRMERDTA 420 + EA L LQ+QINPHFLYN L I + + M LS +RY+ + D Sbjct: 369 KQTEAELANLQSQINPHFLYNTLEAIRMKSLSEGGRTTAKMIVQLSYLFRYSLK-SADLV 427 Query: 421 TLDDEVRLLVNYLDIQKLR-NGRIEYHIDIPQEMLSYSIPRLLLQPIVENSVIHGVGKSY 479 T+ DE++ + Y+++ +R ++ + + + ++ Y +P +LQP++EN +IHG + Sbjct: 428 TIGDELQHVEQYVELFNIRFPNQLTFQVAVEEKHKHYVVPPFILQPLIENFLIHGFKRER 487 Query: 480 SSGEIRISGECSGGCCRVYIDDDGPGLSPEQQEALNRKMREPLQEEMGCGLWNTNQRLIH 539 +I I + ++ I D+G G+ ++ E +N ++ GL+N NQRL Sbjct: 488 DDNQINIIIQEKEQTLQIQIMDNGKGIPRKKVEEINERLSMTENSSHSIGLFNVNQRLRL 547 Query: 540 QFGNHSALHFTESP 553 ++G + P Sbjct: 548 RYGERFGVSVQSEP 561 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.135 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 41,570,933 Number of extensions: 1763596 Number of successful extensions: 15313 Number of sequences better than 1.0e-05: 24 Number of HSP's gapped: 15271 Number of HSP's successfully gapped: 24 Length of query: 588 Length of database: 38,378,431 Length adjustment: 112 Effective length of query: 476 Effective length of database: 25,461,023 Effective search space: 12119446948 Effective search space used: 12119446948 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 119 (50.4 bits)